BR0207321A - Implantes com fk506 - Google Patents

Implantes com fk506

Info

Publication number
BR0207321A
BR0207321A BR0207321-8A BR0207321A BR0207321A BR 0207321 A BR0207321 A BR 0207321A BR 0207321 A BR0207321 A BR 0207321A BR 0207321 A BR0207321 A BR 0207321A
Authority
BR
Brazil
Prior art keywords
covalent
fixed form
active agent
chemically bound
physically fixed
Prior art date
Application number
BR0207321-8A
Other languages
English (en)
Inventor
Stephan Winendt
Randolf Von Oepen
Bernd Kuttler
Gerhard Lang
Original Assignee
Jomed Gmbh
Fujisawa Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2001107339 external-priority patent/DE10107339A1/de
Priority claimed from DE2001127011 external-priority patent/DE10127011A1/de
Priority claimed from DE2001127330 external-priority patent/DE10127330A1/de
Application filed by Jomed Gmbh, Fujisawa Pharmaceutical Co filed Critical Jomed Gmbh
Publication of BR0207321A publication Critical patent/BR0207321A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06—Blood vessels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02—Inorganic materials
    • A61L27/04—Metals or alloys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/416—Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/606—Coatings

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Vascular Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Surgery (AREA)
  • Cardiology (AREA)
  • Inorganic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pulmonology (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Glass Compositions (AREA)

Abstract

"IMPLANTES COM FK506". A invenção refere-se a implantes, em particular intracavernoso ou intravascular, preferivelmente para o tratamento ou profilaxia de constrições vascular periférica ou cornária ou oclusões vasculares, em particular de constrições e estenoses ou restenoses, preferivelmente para a profilaxia de restenose, que compreende FK506 na forma química covalentemente ligada ou não covalentemente ligada ou fisicamente imobilizada, processos para a produção dos mesmos e ao uso dos mesmos.
BR0207321-8A 2001-02-16 2002-02-18 Implantes com fk506 BR0207321A (pt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE2001107339 DE10107339A1 (de) 2001-02-16 2001-02-16 Stent für koronaren und peripheren Einsatz
DE2001127011 DE10127011A1 (de) 2001-06-05 2001-06-05 Implantate mit FK506
DE2001127330 DE10127330A1 (de) 2001-06-06 2001-06-06 Implantate mit FK506 (b)
PCT/EP2002/001707 WO2002065947A2 (de) 2001-02-16 2002-02-18 Implante mit fk506 zur restenosebehandlung und -prophylaxe

Publications (1)

Publication Number Publication Date
BR0207321A true BR0207321A (pt) 2004-02-10

Family

ID=27214297

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0207321-8A BR0207321A (pt) 2001-02-16 2002-02-18 Implantes com fk506

Country Status (13)

Country Link
US (2) US8187320B2 (pt)
EP (2) EP1842569A3 (pt)
JP (1) JP4290985B2 (pt)
KR (2) KR100994543B1 (pt)
CN (1) CN100469394C (pt)
AT (1) ATE368482T1 (pt)
AU (2) AU2002233342B2 (pt)
BR (1) BR0207321A (pt)
CA (1) CA2435306C (pt)
DE (1) DE50210591D1 (pt)
IL (2) IL156887A0 (pt)
NZ (1) NZ540000A (pt)
WO (1) WO2002065947A2 (pt)

Cited By (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7931683B2 (en) 2007-07-27 2011-04-26 Boston Scientific Scimed, Inc. Articles having ceramic coated surfaces
US7938855B2 (en) 2007-11-02 2011-05-10 Boston Scientific Scimed, Inc. Deformable underlayer for stent
US7942926B2 (en) 2007-07-11 2011-05-17 Boston Scientific Scimed, Inc. Endoprosthesis coating
US7976915B2 (en) 2007-05-23 2011-07-12 Boston Scientific Scimed, Inc. Endoprosthesis with select ceramic morphology
US7981150B2 (en) 2006-11-09 2011-07-19 Boston Scientific Scimed, Inc. Endoprosthesis with coatings
US8002823B2 (en) 2007-07-11 2011-08-23 Boston Scientific Scimed, Inc. Endoprosthesis coating
US8029554B2 (en) 2007-11-02 2011-10-04 Boston Scientific Scimed, Inc. Stent with embedded material
US8067054B2 (en) 2007-04-05 2011-11-29 Boston Scientific Scimed, Inc. Stents with ceramic drug reservoir layer and methods of making and using the same
US8066763B2 (en) 1998-04-11 2011-11-29 Boston Scientific Scimed, Inc. Drug-releasing stent with ceramic-containing layer
US8071156B2 (en) 2009-03-04 2011-12-06 Boston Scientific Scimed, Inc. Endoprostheses
US8187620B2 (en) 2006-03-27 2012-05-29 Boston Scientific Scimed, Inc. Medical devices comprising a porous metal oxide or metal material and a polymer coating for delivering therapeutic agents
US8216632B2 (en) 2007-11-02 2012-07-10 Boston Scientific Scimed, Inc. Endoprosthesis coating
US8221822B2 (en) 2007-07-31 2012-07-17 Boston Scientific Scimed, Inc. Medical device coating by laser cladding
US8231980B2 (en) 2008-12-03 2012-07-31 Boston Scientific Scimed, Inc. Medical implants including iridium oxide
US8287937B2 (en) 2009-04-24 2012-10-16 Boston Scientific Scimed, Inc. Endoprosthese
US8353949B2 (en) 2006-09-14 2013-01-15 Boston Scientific Scimed, Inc. Medical devices with drug-eluting coating
US8431149B2 (en) 2007-03-01 2013-04-30 Boston Scientific Scimed, Inc. Coated medical devices for abluminal drug delivery
US8449603B2 (en) 2008-06-18 2013-05-28 Boston Scientific Scimed, Inc. Endoprosthesis coating
US8574615B2 (en) 2006-03-24 2013-11-05 Boston Scientific Scimed, Inc. Medical devices having nanoporous coatings for controlled therapeutic agent delivery
US8771343B2 (en) 2006-06-29 2014-07-08 Boston Scientific Scimed, Inc. Medical devices with selective titanium oxide coatings
US8815273B2 (en) 2007-07-27 2014-08-26 Boston Scientific Scimed, Inc. Drug eluting medical devices having porous layers
US8815275B2 (en) 2006-06-28 2014-08-26 Boston Scientific Scimed, Inc. Coatings for medical devices comprising a therapeutic agent and a metallic material
US8900292B2 (en) 2007-08-03 2014-12-02 Boston Scientific Scimed, Inc. Coating for medical device having increased surface area
US8920491B2 (en) 2008-04-22 2014-12-30 Boston Scientific Scimed, Inc. Medical devices having a coating of inorganic material
US8932346B2 (en) 2008-04-24 2015-01-13 Boston Scientific Scimed, Inc. Medical devices having inorganic particle layers
US9284409B2 (en) 2007-07-19 2016-03-15 Boston Scientific Scimed, Inc. Endoprosthesis having a non-fouling surface

Families Citing this family (102)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6774278B1 (en) * 1995-06-07 2004-08-10 Cook Incorporated Coated implantable medical device
US7611533B2 (en) * 1995-06-07 2009-11-03 Cook Incorporated Coated implantable medical device
KR100994543B1 (ko) 2001-02-16 2010-11-16 아스텔라스세이야쿠 가부시키가이샤 Ｆｋ506을 포함하는 이식편
US6613083B2 (en) † 2001-05-02 2003-09-02 Eckhard Alt Stent device and method
WO2003002243A2 (en) 2001-06-27 2003-01-09 Remon Medical Technologies Ltd. Method and device for electrochemical formation of therapeutic species in vivo
US20050065595A1 (en) * 2001-09-03 2005-03-24 David Chaplin Implants containing combretastatin a-4
GB0121980D0 (en) 2001-09-11 2001-10-31 Cathnet Science Holding As Expandable stent
US7309350B2 (en) 2001-12-03 2007-12-18 Xtent, Inc. Apparatus and methods for deployment of vascular prostheses
US8080048B2 (en) 2001-12-03 2011-12-20 Xtent, Inc. Stent delivery for bifurcated vessels
US7182779B2 (en) 2001-12-03 2007-02-27 Xtent, Inc. Apparatus and methods for positioning prostheses for deployment from a catheter
US7147656B2 (en) 2001-12-03 2006-12-12 Xtent, Inc. Apparatus and methods for delivery of braided prostheses
US7351255B2 (en) 2001-12-03 2008-04-01 Xtent, Inc. Stent delivery apparatus and method
US7137993B2 (en) 2001-12-03 2006-11-21 Xtent, Inc. Apparatus and methods for delivery of multiple distributed stents
US20040186551A1 (en) 2003-01-17 2004-09-23 Xtent, Inc. Multiple independent nested stent structures and methods for their preparation and deployment
US7892273B2 (en) 2001-12-03 2011-02-22 Xtent, Inc. Custom length stent apparatus
US7294146B2 (en) 2001-12-03 2007-11-13 Xtent, Inc. Apparatus and methods for delivery of variable length stents
US20030135266A1 (en) 2001-12-03 2003-07-17 Xtent, Inc. Apparatus and methods for delivery of multiple distributed stents
US20040133270A1 (en) * 2002-07-08 2004-07-08 Axel Grandt Drug eluting stent and methods of manufacture
DE10244847A1 (de) * 2002-09-20 2004-04-01 Ulrich Prof. Dr. Speck Medizinische Vorrichtung zur Arzneimittelabgabe
DE60226236T3 (de) * 2002-09-20 2011-12-15 Abbott Laboratories Vascular Enterprises Ltd. Mit einer rauhen Oberfläche versehener Stent und sein Herstellungsverfahren
RU2005118750A (ru) * 2002-11-15 2006-03-20 Новартис АГ (CH) Органические соединения
US8685428B2 (en) * 2002-12-10 2014-04-01 Advanced Cardiovascular Systems, Inc. Therapeutic composition and a method of coating implantable medical devices
ATE538820T1 (de) 2003-02-21 2012-01-15 Sorin Biomedica Cardio Srl Verfahren zur herstellung eines stents und entsprechender stent
EP1603485A4 (en) * 2003-02-26 2011-03-30 Medivas Llc BIOACTIVE STENTS AND METHOD OF USE THEREOF
US20040236414A1 (en) * 2003-05-23 2004-11-25 Brar Balbir S. Devices and methods for treatment of stenotic regions
US7241308B2 (en) 2003-06-09 2007-07-10 Xtent, Inc. Stent deployment systems and methods
US7326236B2 (en) 2003-12-23 2008-02-05 Xtent, Inc. Devices and methods for controlling and indicating the length of an interventional element
ITTO20040056A1 (it) * 2004-02-05 2004-05-05 Sorin Biomedica Cardio Spa Stent per l'erogazione endoliminale di principi o agenti attivi
US8399609B2 (en) 2004-03-05 2013-03-19 Regenerx Biopharmaceuticals, Inc. Treating or preventing extracellular matrix build-up
US7323006B2 (en) 2004-03-30 2008-01-29 Xtent, Inc. Rapid exchange interventional devices and methods
AU2005231458A1 (en) * 2004-04-05 2005-10-20 Medivas, Llc Bioactive stents for type II diabetics and methods for use thereof
US8317859B2 (en) 2004-06-28 2012-11-27 J.W. Medical Systems Ltd. Devices and methods for controlling expandable prostheses during deployment
US20050288766A1 (en) 2004-06-28 2005-12-29 Xtent, Inc. Devices and methods for controlling expandable prostheses during deployment
US7919110B2 (en) * 2005-01-25 2011-04-05 Boston Scientific Scimed, Inc. Medical device drug release regions containing non-covalently bound polymers
US9452001B2 (en) * 2005-02-22 2016-09-27 Tecres S.P.A. Disposable device for treatment of infections of human limbs
US20060222627A1 (en) * 2005-03-30 2006-10-05 Andrew Carter Optimizing pharmacodynamics of therapeutic agents for treating vascular tissue
US9034025B2 (en) 2005-05-23 2015-05-19 Ostial Corporation Balloon catheters and methods for use
US8118852B2 (en) * 2005-07-13 2012-02-21 Cook Medical Technologies Llc Introducer for self-expandable medical device
US8702777B2 (en) * 2005-08-22 2014-04-22 Incept, Llc Steep-taper flared stents and apparatus and methods for delivering them
US8192483B2 (en) 2005-10-06 2012-06-05 Kaneka Corporation Stent to be placed in the living body
EP1933785B1 (en) * 2005-10-14 2015-04-22 Abbott Laboratories Compositions, systems, kits, and methods of administering rapamycin analogs with paclitaxel using medical devices
US8840660B2 (en) 2006-01-05 2014-09-23 Boston Scientific Scimed, Inc. Bioerodible endoprostheses and methods of making the same
US8089029B2 (en) 2006-02-01 2012-01-03 Boston Scientific Scimed, Inc. Bioabsorbable metal medical device and method of manufacture
WO2007109621A2 (en) * 2006-03-20 2007-09-27 Xtent, Inc. Apparatus and methods for deployment of linked prosthetic segments
US20070224234A1 (en) * 2006-03-22 2007-09-27 Mark Steckel Medical devices having biodegradable polymeric regions
DE102006016598A1 (de) * 2006-04-06 2007-11-15 Heraeus Kulzer Gmbh Beschichtete Vaskulärimplantate
US8048150B2 (en) 2006-04-12 2011-11-01 Boston Scientific Scimed, Inc. Endoprosthesis having a fiber meshwork disposed thereon
US8052743B2 (en) 2006-08-02 2011-11-08 Boston Scientific Scimed, Inc. Endoprosthesis with three-dimensional disintegration control
US8088789B2 (en) 2006-09-13 2012-01-03 Elixir Medical Corporation Macrocyclic lactone compounds and methods for their use
WO2008033956A2 (en) 2006-09-13 2008-03-20 Elixir Medical Corporation Macrocyclic lactone compounds and methods for their use
US10695327B2 (en) 2006-09-13 2020-06-30 Elixir Medical Corporation Macrocyclic lactone compounds and methods for their use
CA2663271A1 (en) 2006-09-15 2008-03-20 Boston Scientific Limited Bioerodible endoprostheses and methods of making the same
JP2010503491A (ja) * 2006-09-15 2010-02-04 ボストン サイエンティフィック リミテッド 生物学的安定性無機層を有する生浸食性エンドプロスシーシス
EP2081616B1 (en) 2006-09-15 2017-11-01 Boston Scientific Scimed, Inc. Bioerodible endoprostheses and methods of making the same
WO2008034013A2 (en) 2006-09-15 2008-03-20 Boston Scientific Limited Medical devices and methods of making the same
CA2663762A1 (en) 2006-09-18 2008-03-27 Boston Scientific Limited Endoprostheses
US20080294236A1 (en) * 2007-05-23 2008-11-27 Boston Scientific Scimed, Inc. Endoprosthesis with Select Ceramic and Polymer Coatings
US20080181928A1 (en) * 2006-12-22 2008-07-31 Miv Therapeutics, Inc. Coatings for implantable medical devices for liposome delivery
ATE488259T1 (de) 2006-12-28 2010-12-15 Boston Scient Ltd Bioerodierbare endoprothesen und herstellungsverfahren dafür
US20080199510A1 (en) 2007-02-20 2008-08-21 Xtent, Inc. Thermo-mechanically controlled implants and methods of use
US8070797B2 (en) 2007-03-01 2011-12-06 Boston Scientific Scimed, Inc. Medical device with a porous surface for delivery of a therapeutic agent
US8486132B2 (en) 2007-03-22 2013-07-16 J.W. Medical Systems Ltd. Devices and methods for controlling expandable prostheses during deployment
US8052745B2 (en) 2007-09-13 2011-11-08 Boston Scientific Scimed, Inc. Endoprosthesis
US20090076591A1 (en) * 2007-09-19 2009-03-19 Boston Scientific Scimed, Inc. Stent Design Allowing Extended Release of Drug and/or Enhanced Adhesion of Polymer to OD Surface
CN101918050A (zh) * 2007-10-10 2010-12-15 Miv治疗有限公司 用于植入式医疗器械的脂质涂层
US7833266B2 (en) * 2007-11-28 2010-11-16 Boston Scientific Scimed, Inc. Bifurcated stent with drug wells for specific ostial, carina, and side branch treatment
US9101503B2 (en) 2008-03-06 2015-08-11 J.W. Medical Systems Ltd. Apparatus having variable strut length and methods of use
US7998192B2 (en) 2008-05-09 2011-08-16 Boston Scientific Scimed, Inc. Endoprostheses
US8236046B2 (en) 2008-06-10 2012-08-07 Boston Scientific Scimed, Inc. Bioerodible endoprosthesis
US7951193B2 (en) * 2008-07-23 2011-05-31 Boston Scientific Scimed, Inc. Drug-eluting stent
US7985252B2 (en) 2008-07-30 2011-07-26 Boston Scientific Scimed, Inc. Bioerodible endoprosthesis
US12076258B2 (en) 2008-09-25 2024-09-03 Advanced Bifurcation Systems Inc. Selective stent crimping
US11298252B2 (en) 2008-09-25 2022-04-12 Advanced Bifurcation Systems Inc. Stent alignment during treatment of a bifurcation
US8821562B2 (en) 2008-09-25 2014-09-02 Advanced Bifurcation Systems, Inc. Partially crimped stent
AU2009296415B2 (en) 2008-09-25 2015-11-19 Advanced Bifurcation Systems Inc. Partially crimped stent
US8828071B2 (en) 2008-09-25 2014-09-09 Advanced Bifurcation Systems, Inc. Methods and systems for ostial stenting of a bifurcation
US8382824B2 (en) 2008-10-03 2013-02-26 Boston Scientific Scimed, Inc. Medical implant having NANO-crystal grains with barrier layers of metal nitrides or fluorides
US8267992B2 (en) 2009-03-02 2012-09-18 Boston Scientific Scimed, Inc. Self-buffering medical implants
US9265633B2 (en) 2009-05-20 2016-02-23 480 Biomedical, Inc. Drug-eluting medical implants
US8888840B2 (en) * 2009-05-20 2014-11-18 Boston Scientific Scimed, Inc. Drug eluting medical implant
US20110319987A1 (en) * 2009-05-20 2011-12-29 Arsenal Medical Medical implant
WO2010135433A1 (en) * 2009-05-20 2010-11-25 Arsenal Medical, Inc. Medical implant
NZ597307A (en) * 2009-06-02 2014-04-30 Concept Medical Inc Rejuvenating coronary artery by improving blood flow with the help of insertion of nano-balls (encapsulated nanoparticles) containing therapeutic agents by non implantable device for tissues and thereby providing in tissue release to address the required cell cycle
KR101060607B1 (ko) 2009-07-09 2011-08-31 전남대학교산학협력단 티탄산화물 박막코팅을 이용한 약물방출 스텐트의 제조방법
US8668732B2 (en) 2010-03-23 2014-03-11 Boston Scientific Scimed, Inc. Surface treated bioerodible metal endoprostheses
CN103037816B (zh) 2010-03-24 2018-12-28 高级分支系统股份有限公司 用于处理分叉部的系统和方法
AU2011232360B2 (en) 2010-03-24 2015-10-08 Advanced Bifurcation Systems Inc. Methods and systems for treating a bifurcation with provisional side branch stenting
CA2794078A1 (en) 2010-03-24 2011-09-29 Advanced Bifurcation Systems, Inc. Stent alignment during treatment of a bifurcation
WO2012109382A2 (en) 2011-02-08 2012-08-16 Advanced Bifurcation Systems, Inc. Multi-stent and multi-balloon apparatus for treating bifurcations and methods of use
EP3777780B1 (en) 2011-02-08 2024-04-24 Advanced Bifurcation Systems Inc. System for treating a bifurcation with a fully crimped stent
US9005270B2 (en) * 2012-03-27 2015-04-14 Medtronic Vascular, Inc. High metal to vessel ratio stent and method
KR101649305B1 (ko) 2015-03-03 2016-08-18 한국전기연구원 표면에 요철이 형성된 의료용 스텐트 및 그 제조방법
WO2018226991A1 (en) 2017-06-07 2018-12-13 Shifamed Holdings, Llc Intravascular fluid movement devices, systems, and methods of use
US11529318B2 (en) * 2017-06-23 2022-12-20 University of Pittsburgh—of the Commonwealth System of Higher Education Devices and methods for local delivery of tacrolimus
CN111556763B (zh) 2017-11-13 2023-09-01 施菲姆德控股有限责任公司 血管内流体运动装置、系统
EP4085965A1 (en) 2018-02-01 2022-11-09 Shifamed Holdings, LLC Intravascular blood pumps and methods of use and manufacture
JP2022540616A (ja) 2019-07-12 2022-09-16 シファメド・ホールディングス・エルエルシー 血管内血液ポンプならびに製造および使用の方法
US11654275B2 (en) 2019-07-22 2023-05-23 Shifamed Holdings, Llc Intravascular blood pumps with struts and methods of use and manufacture
WO2021041505A1 (en) * 2019-08-26 2021-03-04 Forman, Mervyn B. Medical devices for continuous delivery of therapeutic agents
WO2021062270A1 (en) 2019-09-25 2021-04-01 Shifamed Holdings, Llc Catheter blood pumps and collapsible pump housings
EP4034192A4 (en) 2019-09-25 2023-11-29 Shifamed Holdings, LLC INTRAVASCULAR BLOOD PUMP SYSTEMS AND METHODS OF USE AND CONTROL THEREOF
KR102532990B1 (ko) 2021-01-28 2023-05-15 경북대학교 산학협력단 레이저를 이용한 의료용 스텐트 제조방법

Family Cites Families (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0431046B1 (en) 1988-08-24 1995-05-03 SLEPIAN, Marvin J. Biodegradable polymeric endoluminal sealing
US5477864A (en) * 1989-12-21 1995-12-26 Smith & Nephew Richards, Inc. Cardiovascular guidewire of enhanced biocompatibility
IL94138A (en) * 1990-04-19 1997-03-18 Instent Inc Device for the treatment of constricted fluid conducting ducts
US5411552A (en) * 1990-05-18 1995-05-02 Andersen; Henning R. Valve prothesis for implantation in the body and a catheter for implanting such valve prothesis
US5443498A (en) 1991-10-01 1995-08-22 Cook Incorporated Vascular stent and method of making and implanting a vacsular stent
US5464450A (en) 1991-10-04 1995-11-07 Scimed Lifesystems Inc. Biodegradable drug delivery vascular stent
US5500013A (en) 1991-10-04 1996-03-19 Scimed Life Systems, Inc. Biodegradable drug delivery vascular stent
PT100944B (pt) 1991-10-10 2000-02-29 Alza Corp Dispositivo para o fornecimento osmotico de farmacos com paredes de materiais hidrofobicos
US5449382A (en) 1992-11-04 1995-09-12 Dayton; Michael P. Minimally invasive bioactivated endoprosthesis for vessel repair
US5443458A (en) 1992-12-22 1995-08-22 Advanced Cardiovascular Systems, Inc. Multilayered biodegradable stent and method of manufacture
JPH0767895A (ja) 1993-06-25 1995-03-14 Sumitomo Electric Ind Ltd 抗菌性人工血管及び抗菌性手術用縫合糸
US5519042A (en) * 1994-01-13 1996-05-21 Hoechst Aktiengesellschaft Method of treating hyperproliferative vascular disease
US5891108A (en) 1994-09-12 1999-04-06 Cordis Corporation Drug delivery stent
GB2308546B (en) * 1994-10-26 1999-06-02 Novartis Ag Topical macrolide compositions
WO1996026682A1 (en) 1995-02-27 1996-09-06 Instent, Inc. Hollow stent
US6099562A (en) 1996-06-13 2000-08-08 Schneider (Usa) Inc. Drug coating with topcoat
CA2178541C (en) * 1995-06-07 2009-11-24 Neal E. Fearnot Implantable medical device
US6132765A (en) * 1996-04-12 2000-10-17 Uroteq Inc. Drug delivery via therapeutic hydrogels
KR0176334B1 (ko) 1996-08-19 1999-04-01 박원훈 내인체 감염성 삽입금속표면의 코팅방법 및 그 치료기술
ZA9710342B (en) * 1996-11-25 1998-06-10 Alza Corp Directional drug delivery stent and method of use.
US5997517A (en) * 1997-01-27 1999-12-07 Sts Biopolymers, Inc. Bonding layers for medical device surface coatings
US5843172A (en) 1997-04-15 1998-12-01 Advanced Cardiovascular Systems, Inc. Porous medicated stent
US5836966A (en) 1997-05-22 1998-11-17 Scimed Life Systems, Inc. Variable expansion force stent
KR100244164B1 (ko) * 1997-07-15 2000-03-02 김용옥 수용성 고분자-타크로리무스 접합체 화합물 및 그의 제조 방법
DE19744135C1 (de) * 1997-09-29 1999-03-25 Schering Ag Beschichtete medizinische Implantate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Restenoseprophylaxe
US5972027A (en) 1997-09-30 1999-10-26 Scimed Life Systems, Inc Porous stent drug delivery system
US6153252A (en) * 1998-06-30 2000-11-28 Ethicon, Inc. Process for coating stents
IL125336A0 (en) * 1998-07-14 1999-03-12 Yissum Res Dev Co Compositions for inhibition and treatment of restinosis
US20020038146A1 (en) 1998-07-29 2002-03-28 Ulf Harry Expandable stent with relief cuts for carrying medicines and other materials
AUPP584198A0 (en) * 1998-09-14 1998-10-08 Fujisawa Pharmaceutical Co., Ltd. New use
US6358276B1 (en) 1998-09-30 2002-03-19 Impra, Inc. Fluid containing endoluminal stent
US6245104B1 (en) 1999-02-28 2001-06-12 Inflow Dynamics Inc. Method of fabricating a biocompatible stent
DE19855421C2 (de) * 1998-11-02 2001-09-20 Alcove Surfaces Gmbh Implantat
US6214042B1 (en) 1998-11-10 2001-04-10 Precision Vascular Systems, Inc. Micro-machined stent for vessels, body ducts and the like
EP1057460A1 (en) 1999-06-01 2000-12-06 Numed, Inc. Replacement valve assembly and method of implanting same
AU1366701A (en) 1999-09-23 2001-04-24 Clarence C. Lee Antimicrobial and anti-inflammatory endovascular (cardiovascular) stent
ATE425738T1 (de) 1999-11-17 2009-04-15 Boston Scient Ltd Miniaturisierte vorrichtungen zur abgabe von molekulen in einer tragerflussigkeit
US6776796B2 (en) 2000-05-12 2004-08-17 Cordis Corportation Antiinflammatory drug and delivery device
US6709451B1 (en) 2000-07-14 2004-03-23 Norman Noble, Inc. Channeled vascular stent apparatus and method
US6758859B1 (en) 2000-10-30 2004-07-06 Kenny L. Dang Increased drug-loading and reduced stress drug delivery device
US6471980B2 (en) 2000-12-22 2002-10-29 Avantec Vascular Corporation Intravascular delivery of mycophenolic acid
US7077859B2 (en) 2000-12-22 2006-07-18 Avantec Vascular Corporation Apparatus and methods for variably controlled substance delivery from implanted prostheses
CN1360951A (zh) * 2000-12-28 2002-07-31 微创医疗器械(上海)有限公司 一种具有防再狭窄涂层的血管支架
US6752829B2 (en) 2001-01-30 2004-06-22 Scimed Life Systems, Inc. Stent with channel(s) for containing and delivering a biologically active material and method for manufacturing the same
KR100994543B1 (ko) 2001-02-16 2010-11-16 아스텔라스세이야쿠 가부시키가이샤 Ｆｋ506을 포함하는 이식편
US6613083B2 (en) * 2001-05-02 2003-09-02 Eckhard Alt Stent device and method
US6685745B2 (en) 2001-05-15 2004-02-03 Scimed Life Systems, Inc. Delivering an agent to a patient's body
KR20040076278A (ko) * 2002-01-10 2004-08-31 노파르티스 아게 라파마이신 및 그의 유도체를 포함하는, 혈관 질환의 예방및 치료를 위한 약물 전달 시스템
US20040133270A1 (en) 2002-07-08 2004-07-08 Axel Grandt Drug eluting stent and methods of manufacture

Cited By (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8066763B2 (en) 1998-04-11 2011-11-29 Boston Scientific Scimed, Inc. Drug-releasing stent with ceramic-containing layer
US8574615B2 (en) 2006-03-24 2013-11-05 Boston Scientific Scimed, Inc. Medical devices having nanoporous coatings for controlled therapeutic agent delivery
US8187620B2 (en) 2006-03-27 2012-05-29 Boston Scientific Scimed, Inc. Medical devices comprising a porous metal oxide or metal material and a polymer coating for delivering therapeutic agents
US8815275B2 (en) 2006-06-28 2014-08-26 Boston Scientific Scimed, Inc. Coatings for medical devices comprising a therapeutic agent and a metallic material
US8771343B2 (en) 2006-06-29 2014-07-08 Boston Scientific Scimed, Inc. Medical devices with selective titanium oxide coatings
US8353949B2 (en) 2006-09-14 2013-01-15 Boston Scientific Scimed, Inc. Medical devices with drug-eluting coating
US7981150B2 (en) 2006-11-09 2011-07-19 Boston Scientific Scimed, Inc. Endoprosthesis with coatings
US8431149B2 (en) 2007-03-01 2013-04-30 Boston Scientific Scimed, Inc. Coated medical devices for abluminal drug delivery
US8067054B2 (en) 2007-04-05 2011-11-29 Boston Scientific Scimed, Inc. Stents with ceramic drug reservoir layer and methods of making and using the same
US7976915B2 (en) 2007-05-23 2011-07-12 Boston Scientific Scimed, Inc. Endoprosthesis with select ceramic morphology
US8002823B2 (en) 2007-07-11 2011-08-23 Boston Scientific Scimed, Inc. Endoprosthesis coating
US7942926B2 (en) 2007-07-11 2011-05-17 Boston Scientific Scimed, Inc. Endoprosthesis coating
US9284409B2 (en) 2007-07-19 2016-03-15 Boston Scientific Scimed, Inc. Endoprosthesis having a non-fouling surface
US8815273B2 (en) 2007-07-27 2014-08-26 Boston Scientific Scimed, Inc. Drug eluting medical devices having porous layers
US7931683B2 (en) 2007-07-27 2011-04-26 Boston Scientific Scimed, Inc. Articles having ceramic coated surfaces
US8221822B2 (en) 2007-07-31 2012-07-17 Boston Scientific Scimed, Inc. Medical device coating by laser cladding
US8900292B2 (en) 2007-08-03 2014-12-02 Boston Scientific Scimed, Inc. Coating for medical device having increased surface area
US8216632B2 (en) 2007-11-02 2012-07-10 Boston Scientific Scimed, Inc. Endoprosthesis coating
US8029554B2 (en) 2007-11-02 2011-10-04 Boston Scientific Scimed, Inc. Stent with embedded material
US7938855B2 (en) 2007-11-02 2011-05-10 Boston Scientific Scimed, Inc. Deformable underlayer for stent
US8920491B2 (en) 2008-04-22 2014-12-30 Boston Scientific Scimed, Inc. Medical devices having a coating of inorganic material
US8932346B2 (en) 2008-04-24 2015-01-13 Boston Scientific Scimed, Inc. Medical devices having inorganic particle layers
US8449603B2 (en) 2008-06-18 2013-05-28 Boston Scientific Scimed, Inc. Endoprosthesis coating
US8231980B2 (en) 2008-12-03 2012-07-31 Boston Scientific Scimed, Inc. Medical implants including iridium oxide
US8071156B2 (en) 2009-03-04 2011-12-06 Boston Scientific Scimed, Inc. Endoprostheses
US8287937B2 (en) 2009-04-24 2012-10-16 Boston Scientific Scimed, Inc. Endoprosthese

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US20040117008A1 (en) 2004-06-17
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EP1372753A2 (de) 2004-01-02
KR20090130879A (ko) 2009-12-24
JP2004531299A (ja) 2004-10-14
CN1547490A (zh) 2004-11-17
CN100469394C (zh) 2009-03-18
CA2435306A1 (en) 2002-08-29
NZ540000A (en) 2007-05-31
DE50210591D1 (de) 2007-09-13
WO2002065947A2 (de) 2002-08-29
CA2435306C (en) 2010-12-21
AU2002233342B2 (en) 2007-10-25
KR100994543B1 (ko) 2010-11-16
WO2002065947A3 (de) 2003-09-18
EP1842569A2 (de) 2007-10-10
EP1372753B1 (de) 2007-08-01
ATE368482T1 (de) 2007-08-15
KR20040011463A (ko) 2004-02-05
JP4290985B2 (ja) 2009-07-08
US20120239139A1 (en) 2012-09-20
IL156887A (en) 2009-09-01
AU2008200300B2 (en) 2011-04-21
AU2008200300A1 (en) 2008-02-14
IL156887A0 (en) 2004-02-08

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