JP2005523309A5 - - Google Patents

Info

Publication number

JP2005523309A5

JP2005523309A5 JP2003583368A JP2003583368A JP2005523309A5 JP 2005523309 A5 JP2005523309 A5 JP 2005523309A5 JP 2003583368 A JP2003583368 A JP 2003583368A JP 2003583368 A JP2003583368 A JP 2003583368A JP 2005523309 A5 JP2005523309 A5 JP 2005523309A5

Authority

JP

Japan

Prior art keywords

dosage form

antibiotic

product

max

dosage

Prior art date

2002-12-20

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Withdrawn

Links

• Espacenet
• Global Dossier
• Discuss

• 239000002552 dosage form Substances 0.000 claims 54
• 230000003115 biocidal effect Effects 0.000 claims 32
• 239000003242 anti bacterial agent Substances 0.000 claims 10
• 229940088710 antibiotic agent Drugs 0.000 claims 8
• 210000002966 serum Anatomy 0.000 claims 6
• ULGZDMOVFRHVEP-RWJQBGPGSA-N Erythromycin Chemical compound O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 ULGZDMOVFRHVEP-RWJQBGPGSA-N 0.000 claims 4
• MYSWGUAQZAJSOK-UHFFFAOYSA-N ciprofloxacin Chemical compound C12=CC(N3CCNCC3)=C(F)C=C2C(=O)C(C(=O)O)=CN1C1CC1 MYSWGUAQZAJSOK-UHFFFAOYSA-N 0.000 claims 4
• 230000003111 delayed effect Effects 0.000 claims 4
• SGKRLCUYIXIAHR-AKNGSSGZSA-N (4s,4ar,5s,5ar,6r,12ar)-4-(dimethylamino)-1,5,10,11,12a-pentahydroxy-6-methyl-3,12-dioxo-4a,5,5a,6-tetrahydro-4h-tetracene-2-carboxamide Chemical compound C1=CC=C2[C@H](C)[C@@H]([C@H](O)[C@@H]3[C@](C(O)=C(C(N)=O)C(=O)[C@H]3N(C)C)(O)C3=O)C3=C(O)C2=C1O SGKRLCUYIXIAHR-AKNGSSGZSA-N 0.000 claims 2
• 229930186147 Cephalosporin Natural products 0.000 claims 2
• -1 Fururokiniron Chemical compound 0.000 claims 2
• GSDSWSVVBLHKDQ-JTQLQIEISA-N Levofloxacin Chemical compound C([C@@H](N1C2=C(C(C(C(O)=O)=C1)=O)C=C1F)C)OC2=C1N1CCN(C)CC1 GSDSWSVVBLHKDQ-JTQLQIEISA-N 0.000 claims 2
• 229930182555 Penicillin Natural products 0.000 claims 2
• JGSARLDLIJGVTE-MBNYWOFBSA-N Penicillin G Chemical compound N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)CC1=CC=CC=C1 JGSARLDLIJGVTE-MBNYWOFBSA-N 0.000 claims 2
• 239000004098 Tetracycline Substances 0.000 claims 2
• 229960003022 amoxicillin Drugs 0.000 claims 2
• LSQZJLSUYDQPKJ-NJBDSQKTSA-N amoxicillin Chemical compound C1([C@@H](N)C(=O)N[C@H]2[C@H]3SC([C@@H](N3C2=O)C(O)=O)(C)C)=CC=C(O)C=C1 LSQZJLSUYDQPKJ-NJBDSQKTSA-N 0.000 claims 2
• 229960005090 cefpodoxime Drugs 0.000 claims 2
• WYUSVOMTXWRGEK-HBWVYFAYSA-N cefpodoxime Chemical compound N([C@H]1[C@@H]2N(C1=O)C(=C(CS2)COC)C(O)=O)C(=O)C(=N/OC)\C1=CSC(N)=N1 WYUSVOMTXWRGEK-HBWVYFAYSA-N 0.000 claims 2
• 229960001668 cefuroxime Drugs 0.000 claims 2
• JFPVXVDWJQMJEE-IZRZKJBUSA-N cefuroxime Chemical compound N([C@@H]1C(N2C(=C(COC(N)=O)CS[C@@H]21)C(O)=O)=O)C(=O)\C(=N/OC)C1=CC=CO1 JFPVXVDWJQMJEE-IZRZKJBUSA-N 0.000 claims 2
• 229940124587 cephalosporin Drugs 0.000 claims 2
• 150000001780 cephalosporins Chemical class 0.000 claims 2
• 229960003405 ciprofloxacin Drugs 0.000 claims 2
• 229960002626 clarithromycin Drugs 0.000 claims 2
• AGOYDEPGAOXOCK-KCBOHYOISA-N clarithromycin Chemical compound O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@](C)([C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)OC)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 AGOYDEPGAOXOCK-KCBOHYOISA-N 0.000 claims 2
• 229960001585 dicloxacillin Drugs 0.000 claims 2
• YFAGHNZHGGCZAX-JKIFEVAISA-N dicloxacillin Chemical compound N([C@@H]1C(N2[C@H](C(C)(C)S[C@@H]21)C(O)=O)=O)C(=O)C1=C(C)ON=C1C1=C(Cl)C=CC=C1Cl YFAGHNZHGGCZAX-JKIFEVAISA-N 0.000 claims 2
• 229960003722 doxycycline Drugs 0.000 claims 2
• 229960003276 erythromycin Drugs 0.000 claims 2
• 239000012729 immediate-release (IR) formulation Substances 0.000 claims 2
• 229960003376 levofloxacin Drugs 0.000 claims 2
• 229960000282 metronidazole Drugs 0.000 claims 2
• VAOCPAMSLUNLGC-UHFFFAOYSA-N metronidazole Chemical compound CC1=NC=C([N+]([O-])=O)N1CCO VAOCPAMSLUNLGC-UHFFFAOYSA-N 0.000 claims 2
• LSQZJLSUYDQPKJ-UHFFFAOYSA-N p-Hydroxyampicillin Natural products O=C1N2C(C(O)=O)C(C)(C)SC2C1NC(=O)C(N)C1=CC=C(O)C=C1 LSQZJLSUYDQPKJ-UHFFFAOYSA-N 0.000 claims 2
• 229940049954 penicillin Drugs 0.000 claims 2
• 229960002180 tetracycline Drugs 0.000 claims 2
• 229930101283 tetracycline Natural products 0.000 claims 2
• 235000019364 tetracycline Nutrition 0.000 claims 2
• 150000003522 tetracyclines Chemical class 0.000 claims 2
• 208000035143 Bacterial infection Diseases 0.000 claims 1
• 208000022362 bacterial infectious disease Diseases 0.000 claims 1
• 239000003782 beta lactam antibiotic agent Substances 0.000 claims 1
• 239000003814 drug Substances 0.000 claims 1
• 229940079593 drug Drugs 0.000 claims 1
• 239000002132 β-lactam antibiotic Substances 0.000 claims 1
• 229940124586 β-lactam antibiotics Drugs 0.000 claims 1