JP2005519636A - Posh核酸、ポリペプチド及び関連する方法、関連する用途 - Google Patents

Posh核酸、ポリペプチド及び関連する方法、関連する用途 Download PDF

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Publication number
JP2005519636A
JP2005519636A JP2004503917A JP2004503917A JP2005519636A JP 2005519636 A JP2005519636 A JP 2005519636A JP 2004503917 A JP2004503917 A JP 2004503917A JP 2004503917 A JP2004503917 A JP 2004503917A JP 2005519636 A JP2005519636 A JP 2005519636A
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Japan
Prior art keywords
posh
polypeptide
virus
nucleic acid
seq
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JP2004503917A
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Japanese (ja)
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JP2005519636A5 (https=
Inventor
アルロイ,アイリス
グリーナー,ツヴィッカ
トゥヴィア,シュムエル
ベン−アブラハム,ダニー
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Proteologics Inc
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Proteologics Inc
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/93Ligases (6)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y603/00Ligases forming carbon-nitrogen bonds (6.3)
    • C12Y603/02Acid—amino-acid ligases (peptide synthases)(6.3.2)
    • C12Y603/02019Ubiquitin-protein ligase (6.3.2.19), i.e. ubiquitin-conjugating enzyme

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Enzymes And Modification Thereof (AREA)
JP2004503917A 2001-11-09 2002-11-12 Posh核酸、ポリペプチド及び関連する方法、関連する用途 Pending JP2005519636A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US34584601P 2001-11-09 2001-11-09
US36453002P 2002-03-15 2002-03-15
PCT/US2002/036366 WO2003095971A2 (en) 2001-11-09 2002-11-12 Posh nucleic acids, polypeptides and related methods

Publications (2)

Publication Number Publication Date
JP2005519636A true JP2005519636A (ja) 2005-07-07
JP2005519636A5 JP2005519636A5 (https=) 2006-01-05

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ID=26994569

Family Applications (1)

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JP2004503917A Pending JP2005519636A (ja) 2001-11-09 2002-11-12 Posh核酸、ポリペプチド及び関連する方法、関連する用途

Country Status (10)

Country Link
US (4) US7250250B2 (https=)
EP (1) EP1310552B1 (https=)
JP (1) JP2005519636A (https=)
AT (1) ATE364690T1 (https=)
AU (1) AU2002365160C1 (https=)
CA (1) CA2465973C (https=)
DE (1) DE60220621T2 (https=)
IL (2) IL161764A0 (https=)
NZ (1) NZ532908A (https=)
WO (1) WO2003095971A2 (https=)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008092911A (ja) * 2006-10-16 2008-04-24 Univ Of Tokyo タンパク質結合検出方法
WO2009028062A1 (ja) * 2007-08-30 2009-03-05 Mitsui Engineering & Shipbuilding Co., Ltd. Fret検出方法および装置
US12059413B2 (en) 2016-11-02 2024-08-13 The Research Foundation For The State University Of New York Methods of inhibiting viruses using compositions targeting TSG101-ubiquitin interaction

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE602004025708D1 (de) 2003-07-11 2010-04-08 Proteologics Inc Ubiquitin-ligase-hemmer und verwandte verfahren
US20060188890A1 (en) * 2003-10-31 2006-08-24 Proteologics, Inc. Ubiquitin-based protein interaction assays and related compositions
US20060194262A1 (en) * 2004-10-15 2006-08-31 Shuichan Xu P27 ubiquitination assay and methods of use
AU2005311680A1 (en) * 2004-12-01 2006-06-08 Proteologics, Inc. Ubiquitin ligase assays and related reagents
US8691971B2 (en) 2008-09-23 2014-04-08 Scott G. Petersen Self delivering bio-labile phosphate protected pro-oligos for oligonucleotide based therapeutics and mediating RNA interference
WO2015023824A2 (en) * 2013-08-14 2015-02-19 The Curators Of The University Of Missouri Cell permeable inhibitors of the scaffold protein plenty of sh3 domains (posh) or sh3rfl
CN106754883B (zh) * 2016-12-30 2019-10-29 中山大学 一种一步、无缝、非同源、多片段的基因拼接改造方法及其试剂盒
CN112764372A (zh) * 2020-12-25 2021-05-07 天津大学 基于vpx架构的多通道信号采集系统

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000008181A2 (en) * 1998-08-07 2000-02-17 Onyx Pharmaceuticals, Inc. Chp polypeptide, a ligand of pak65
AU6158799A (en) * 1998-10-13 2000-05-01 Onyx Pharmaceuticals, Inc. Novel cell signaling polypeptides and nucleic acids
WO2000027865A1 (en) 1998-11-06 2000-05-18 The Brigham And Women's Hospital, Inc. CHARACTERIZATION OF NOVEL GENE cbl-SL
EP1074617A3 (en) 1999-07-29 2004-04-21 Research Association for Biotechnology Primers for synthesising full-length cDNA and their use
WO2001018542A2 (en) 1999-09-03 2001-03-15 Millennium Pharmaceuticals, Inc. Identification, assessment, prevention, and therapy of ovarian cancer
CA2395872A1 (en) 2000-01-31 2001-08-02 Human Genome Sciences, Inc. Nucleic acids, proteins, and antibodies
CA2399776A1 (en) 2000-02-03 2001-08-09 Hyseq, Inc. Novel nucleic acids and polypeptides
WO2001060860A2 (en) 2000-02-17 2001-08-23 Millennium Predictive Medicine, Inc. Genes differentially expressed in human prostate cancer and their use
AU2001238347A1 (en) 2000-02-28 2001-09-12 Hyseq, Inc. Novel nucleic acids and polypeptides
US20030165831A1 (en) 2000-03-21 2003-09-04 John Lee Novel genes, compositions, kits, and methods for identification, assessment, prevention, and therapy of ovarian cancer
WO2001071042A2 (en) 2000-03-23 2001-09-27 Pe Corporation (Ny) Detection kits, such as nucleic acid arrays, for detecting the expression of 10,000 or more drosophila genes and uses thereof
WO2001077288A2 (en) 2000-04-06 2001-10-18 Genetics Institute, Llc. Polynucleotides encoding novel secreted proteins
AU2001263006A1 (en) 2000-05-18 2001-11-26 Hyseq, Inc. Novel nucleic acids and polypeptides
US7105293B2 (en) 2000-09-19 2006-09-12 Whitehead Institute For Biomedical Research Genetic markers for tumors
AU2002229113A8 (en) 2000-10-20 2009-03-26 Univ Massachusetts Glucose transport-related genes and uses thereof
CA2426540A1 (en) 2000-10-20 2002-07-25 Biocardia, Inc. Leukocyte expression profiling
AU2002241520A1 (en) 2000-11-28 2003-03-03 University Of Cincinnati Blood assessment of injury
WO2002077235A2 (en) 2000-12-21 2002-10-03 Incyte Genomics, Inc. Intracellular signaling molecules
WO2002053719A2 (en) * 2001-01-04 2002-07-11 Incyte Genomics, Inc. Cytoskeleton-associated proteins
JP2005503760A (ja) 2001-01-24 2005-02-10 プロテイン デザイン ラブス, インコーポレイテッド 乳癌の診断方法、組成物および乳癌のモジュレーターのスクリーニング方法
US6743619B1 (en) 2001-01-30 2004-06-01 Nuvelo Nucleic acids and polypeptides
JP2004536575A (ja) 2001-02-28 2004-12-09 コンドロジーン・インコーポレイテッド 変形性関節症に関連する組成物および方法
CA2447183A1 (en) * 2001-03-28 2002-10-10 Incyte Genomics, Inc. Molecules for disease detection and treatment
US20040236091A1 (en) 2001-03-28 2004-11-25 Chicz Roman M. Translational profiling
WO2002085285A2 (en) 2001-04-18 2002-10-31 Wyeth Methods and reagents for regulating bone and cartilage formation
EP1392871A4 (en) 2001-05-22 2006-04-19 Gene Logic Inc MODELING MOLECULAR TOXICITY
WO2003022987A2 (en) 2001-07-26 2003-03-20 Eos Biotechnology, Inc. Methods of diagnosis of hepatitis c infection, compositions and methods of screening for modulators of hepatitis c infection
WO2003033646A2 (en) 2001-07-31 2003-04-24 Proteologics, Inc. Compositions and methods for the modulation of viral maturation
CA2459219A1 (en) 2001-09-17 2003-03-27 Protein Design Labs, Inc. Methods of diagnosis of cancer compositions and methods of screening for modulators of cancer
IL160905A0 (en) 2001-10-31 2004-08-31 Pfizer Prod Inc Therapeutics and diagnostics for disorders of erythropoiesis
WO2003039490A2 (en) 2001-11-09 2003-05-15 Office Of Technology Licensing Stanford University Compositions and methods for diagnosing and treating mental disorders
US20040096828A1 (en) * 2002-01-04 2004-05-20 Lu Dyung Aina M Cytoskeleton-associated proteins

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008092911A (ja) * 2006-10-16 2008-04-24 Univ Of Tokyo タンパク質結合検出方法
WO2009028062A1 (ja) * 2007-08-30 2009-03-05 Mitsui Engineering & Shipbuilding Co., Ltd. Fret検出方法および装置
KR101152615B1 (ko) 2007-08-30 2012-06-07 미쯔이 죠센 가부시키가이샤 형광공명에너지이동 검출 방법 및 장치
US8614099B2 (en) 2007-08-30 2013-12-24 Mitsui Engineering & Shipbuilding Co., Ltd. FRET detection method and device
US12059413B2 (en) 2016-11-02 2024-08-13 The Research Foundation For The State University Of New York Methods of inhibiting viruses using compositions targeting TSG101-ubiquitin interaction

Also Published As

Publication number Publication date
NZ532908A (en) 2008-04-30
WO2003095971A2 (en) 2003-11-20
DE60220621D1 (de) 2007-07-26
AU2002365160B2 (en) 2008-10-30
CA2465973C (en) 2013-04-16
DE60220621T2 (de) 2008-03-06
CA2465973A1 (en) 2003-11-20
ATE364690T1 (de) 2007-07-15
US20080187538A1 (en) 2008-08-07
EP1310552A3 (en) 2003-10-08
EP1310552B1 (en) 2007-06-13
AU2002365160A1 (en) 2003-11-11
HK1055996A1 (en) 2004-01-30
US20060035213A1 (en) 2006-02-16
US7250250B2 (en) 2007-07-31
EP1310552A2 (en) 2003-05-14
US7429643B2 (en) 2008-09-30
IL161764A0 (en) 2005-11-20
US20060019240A1 (en) 2006-01-26
US7268227B2 (en) 2007-09-11
US20040025196A1 (en) 2004-02-05
IL161764A (en) 2010-12-30
WO2003095971A3 (en) 2005-04-28
AU2002365160C1 (en) 2009-08-13

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