JP2005519635A - 活性クロマチンエレメントを含むdnaマイクロアレイおよびそれを用いた包括的プロファイリング - Google Patents

活性クロマチンエレメントを含むdnaマイクロアレイおよびそれを用いた包括的プロファイリング Download PDF

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JP2005519635A
JP2005519635A JP2004503602A JP2004503602A JP2005519635A JP 2005519635 A JP2005519635 A JP 2005519635A JP 2004503602 A JP2004503602 A JP 2004503602A JP 2004503602 A JP2004503602 A JP 2004503602A JP 2005519635 A JP2005519635 A JP 2005519635A
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dna
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profile
cell
active chromatin
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JP2005519635A5 (enExample
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マッカーサー,マイケル
スタマトヤンノポウロス,ジョン,エー.
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レギュローム コーポレーション
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/102Mutagenizing nucleic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034Isolating an individual clone by screening libraries
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034Isolating an individual clone by screening libraries
    • C12N15/1072Differential gene expression library synthesis, e.g. subtracted libraries, differential screening
    • CCHEMISTRY; METALLURGY
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    • C12N2830/00Vector systems having a special element relevant for transcription
    • C12N2830/80Vector systems having a special element relevant for transcription from vertebrates
    • C12N2830/85Vector systems having a special element relevant for transcription from vertebrates mammalian
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    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6834Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips

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  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
JP2004503602A 2001-05-11 2002-05-13 活性クロマチンエレメントを含むdnaマイクロアレイおよびそれを用いた包括的プロファイリング Pending JP2005519635A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US29003601P 2001-05-11 2001-05-11
PCT/US2002/015032 WO2003095608A2 (en) 2001-05-11 2002-05-13 Dna microarrays comprising active chromatin elements and comprehensive profiling therewith

Publications (2)

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JP2005519635A true JP2005519635A (ja) 2005-07-07
JP2005519635A5 JP2005519635A5 (enExample) 2006-01-05

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JP2004503602A Pending JP2005519635A (ja) 2001-05-11 2002-05-13 活性クロマチンエレメントを含むdnaマイクロアレイおよびそれを用いた包括的プロファイリング

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US (1) US20030170689A1 (enExample)
EP (1) EP1407053A4 (enExample)
JP (1) JP2005519635A (enExample)
AU (1) AU2002367838A1 (enExample)
CA (1) CA2460679A1 (enExample)
WO (1) WO2003095608A2 (enExample)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6610489B2 (en) * 2000-04-28 2003-08-26 Sangamo Biosciences, Inc. Pharmacogenomics and identification of drug targets by reconstruction of signal transduction pathways based on sequences of accessible regions
US20040014086A1 (en) * 2001-05-11 2004-01-22 Regulome Corporation Regulome arrays
CA2450814A1 (en) * 2001-07-02 2003-07-17 The Board Of Trustees Of The Leland Stanford Junior University Microarrays for cell phenotyping and manipulation
US20110151438A9 (en) 2001-11-19 2011-06-23 Affymetrix, Inc. Methods of Analysis of Methylation
US20050003369A1 (en) * 2002-10-10 2005-01-06 Affymetrix, Inc. Method for depleting specific nucleic acids from a mixture
WO2005118873A2 (en) * 2004-05-28 2005-12-15 Cemines, Inc. Compositions and methods for detecting open chromatin and for genome-wide chromatin state profiling
GB0419419D0 (en) * 2004-09-01 2004-10-06 Medical Res Council Method
CA2607327A1 (en) * 2005-04-29 2006-11-09 The Regents Of The University Of California Antibodies against histone modifications for clinical diagnosis and prognosis of cancer
US20060292585A1 (en) * 2005-06-24 2006-12-28 Affymetrix, Inc. Analysis of methylation using nucleic acid arrays
US7901882B2 (en) 2006-03-31 2011-03-08 Affymetrix, Inc. Analysis of methylation using nucleic acid arrays
WO2008024473A2 (en) * 2006-08-24 2008-02-28 University Of Massachusetts Medical School Mapping of genomic interactions
US8076070B2 (en) * 2008-08-06 2011-12-13 University Of Southern California Genome-wide chromosome conformation capture
US10526641B2 (en) * 2014-08-01 2020-01-07 Dovetail Genomics, Llc Tagging nucleic acids for sequence assembly
WO2016154540A1 (en) 2015-03-26 2016-09-29 Dovetail Genomics Llc Physical linkage preservation in dna storage
US10975417B2 (en) 2016-02-23 2021-04-13 Dovetail Genomics, Llc Generation of phased read-sets for genome assembly and haplotype phasing
CN109477101B (zh) 2016-05-13 2022-11-18 多弗泰尔基因组学有限责任公司 从保存的样品中回收长范围连锁信息
US20190234874A1 (en) * 2016-07-19 2019-08-01 Altius Institute For Biomedical Sciences Methods for fluorescence imaging microscopy
CN106987629B (zh) * 2017-03-31 2021-01-15 上海市第一妇婴保健院 一种在单细胞水平上检测基因组上核小体排布的方法
AU2018304396B2 (en) 2017-07-19 2025-01-23 Altius Institute For Biomedical Sciences Methods and compositions for viral Nano-FISH
EP3803404A4 (en) 2018-06-06 2022-03-23 Ramot at Tel-Aviv University Ltd. MULTI-SAMPLE ARRAY CHIP FOR QUANTIFICATION OF DNA CHANGE
GB2581152A (en) * 2019-02-05 2020-08-12 Univ Oxford Innovation Ltd Production of 3C library
CN112973592B (zh) * 2019-12-16 2022-12-09 天津大学 一种基于阵列式喷墨打印的高通量dna合成装置与方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5610053A (en) * 1993-04-07 1997-03-11 The United States Of America As Represented By The Department Of Health And Human Services DNA sequence which acts as a chromatin insulator element to protect expressed genes from cis-acting regulatory sequences in mammalian cells
US6165709A (en) * 1997-02-28 2000-12-26 Fred Hutchinson Cancer Research Center Methods for drug target screening
US5972608A (en) * 1997-08-27 1999-10-26 University Of Massachusetts Assays and reagents for chromatin remodeling enzymes and their modulators

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Publication number Publication date
US20030170689A1 (en) 2003-09-11
AU2002367838A1 (en) 2003-11-11
CA2460679A1 (en) 2003-11-20
WO2003095608A2 (en) 2003-11-20
EP1407053A2 (en) 2004-04-14
EP1407053A4 (en) 2004-09-29
WO2003095608A3 (en) 2004-02-12

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