JP2005519047A5 - - Google Patents
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- Publication number
- JP2005519047A5 JP2005519047A5 JP2003554708A JP2003554708A JP2005519047A5 JP 2005519047 A5 JP2005519047 A5 JP 2005519047A5 JP 2003554708 A JP2003554708 A JP 2003554708A JP 2003554708 A JP2003554708 A JP 2003554708A JP 2005519047 A5 JP2005519047 A5 JP 2005519047A5
- Authority
- JP
- Japan
- Prior art keywords
- ylsulfamate
- trien
- catalyst
- producing
- oxoestradi
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 claims 8
- BDAGIHXWWSANSR-UHFFFAOYSA-N methanoic acid Natural products OC=O BDAGIHXWWSANSR-UHFFFAOYSA-N 0.000 claims 6
- 239000003054 catalyst Substances 0.000 claims 4
- 238000004519 manufacturing process Methods 0.000 claims 4
- OSWFIVFLDKOXQC-UHFFFAOYSA-N 4-(3-methoxyphenyl)aniline Chemical compound COC1=CC=CC(C=2C=CC(N)=CC=2)=C1 OSWFIVFLDKOXQC-UHFFFAOYSA-N 0.000 claims 3
- ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical group CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 claims 3
- 239000003153 chemical reaction reagent Substances 0.000 claims 3
- WRJWRGBVPUUDLA-UHFFFAOYSA-N chlorosulfonyl isocyanate Chemical compound ClS(=O)(=O)N=C=O WRJWRGBVPUUDLA-UHFFFAOYSA-N 0.000 claims 3
- 235000019253 formic acid Nutrition 0.000 claims 3
- QAHVHSLSRLSVGS-UHFFFAOYSA-N sulfamoyl chloride Chemical compound NS(Cl)(=O)=O QAHVHSLSRLSVGS-UHFFFAOYSA-N 0.000 claims 3
- 238000006243 chemical reaction Methods 0.000 claims 2
- DNXHEGUUPJUMQT-UHFFFAOYSA-N (+)-estrone Natural products OC1=CC=C2C3CCC(C)(C(CC4)=O)C4C3CCC2=C1 DNXHEGUUPJUMQT-UHFFFAOYSA-N 0.000 claims 1
- DNXHEGUUPJUMQT-CBZIJGRNSA-N Estrone Chemical compound OC1=CC=C2[C@H]3CC[C@](C)(C(CC4)=O)[C@@H]4[C@@H]3CCC2=C1 DNXHEGUUPJUMQT-CBZIJGRNSA-N 0.000 claims 1
- FXHOOIRPVKKKFG-UHFFFAOYSA-N N,N-Dimethylacetamide Chemical compound CN(C)C(C)=O FXHOOIRPVKKKFG-UHFFFAOYSA-N 0.000 claims 1
- 238000009825 accumulation Methods 0.000 claims 1
- 150000001298 alcohols Chemical class 0.000 claims 1
- -1 carboxamide compound Chemical class 0.000 claims 1
- 229960003399 estrone Drugs 0.000 claims 1
- 150000004678 hydrides Chemical class 0.000 claims 1
- 150000002989 phenols Chemical class 0.000 claims 1
- 239000002904 solvent Substances 0.000 claims 1
- IIACRCGMVDHOTQ-UHFFFAOYSA-N sulfamic acid Chemical class NS(O)(=O)=O IIACRCGMVDHOTQ-UHFFFAOYSA-N 0.000 claims 1
- 238000005849 sulfamoylation reaction Methods 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US34187701P | 2001-12-21 | 2001-12-21 | |
| PCT/EP2002/014487 WO2003053992A2 (en) | 2001-12-21 | 2002-12-18 | Industrially applicable process for the sulfamoylation of alcohols and phenols |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005519047A JP2005519047A (ja) | 2005-06-30 |
| JP2005519047A5 true JP2005519047A5 (https=) | 2005-12-22 |
| JP4347696B2 JP4347696B2 (ja) | 2009-10-21 |
Family
ID=23339393
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003554708A Expired - Fee Related JP4347696B2 (ja) | 2001-12-21 | 2002-12-18 | アルコール及びフェノールのスルファモイル化のための産業的適用方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US7067683B2 (https=) |
| EP (1) | EP1456224B1 (https=) |
| JP (1) | JP4347696B2 (https=) |
| AT (1) | ATE317369T1 (https=) |
| AU (1) | AU2002358755A1 (https=) |
| DE (1) | DE60209149T2 (https=) |
| DK (1) | DK1456224T3 (https=) |
| ES (1) | ES2256576T3 (https=) |
| PT (1) | PT1456224E (https=) |
| WO (1) | WO2003053992A2 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2256576T3 (es) | 2001-12-21 | 2006-07-16 | Schering Aktiengesellschaft | Proceso aplicable industrialmente para la sulfamoilacion de alcoholes y fenoles. |
| WO2009042013A1 (en) | 2007-08-02 | 2009-04-02 | Millennium Pharmaceuticals, Inc. | Process for the synthesis of e1 activating enzyme inhibitors |
| ES2915065T3 (es) | 2008-07-31 | 2022-06-20 | Firmenich Incorporated | Procedimientos para hacer potenciadores del sabor dulce |
| BR112021002261A2 (pt) | 2018-08-07 | 2021-05-04 | Firmenich Incorporated | 2,2-dióxidos de 4-amino-1h-benzo[c][1,2,6]tiadiazina 5-substituídos e formulações e usos dos mesmos |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT94305B (pt) * | 1989-06-12 | 1997-02-28 | Robins Co Inc A H | Processo para a preparacao de compostos tendo um ou mais radicais aminossulfoniloxi uteis como produtos farmaceuticos |
| JP5042411B2 (ja) * | 1999-04-30 | 2012-10-03 | ステリックス リミテッド | 抗腫瘍剤としてのエストロン誘導体の使用 |
| ES2256576T3 (es) | 2001-12-21 | 2006-07-16 | Schering Aktiengesellschaft | Proceso aplicable industrialmente para la sulfamoilacion de alcoholes y fenoles. |
-
2002
- 2002-12-18 ES ES02793067T patent/ES2256576T3/es not_active Expired - Lifetime
- 2002-12-18 JP JP2003554708A patent/JP4347696B2/ja not_active Expired - Fee Related
- 2002-12-18 AT AT02793067T patent/ATE317369T1/de active
- 2002-12-18 WO PCT/EP2002/014487 patent/WO2003053992A2/en not_active Ceased
- 2002-12-18 AU AU2002358755A patent/AU2002358755A1/en not_active Abandoned
- 2002-12-18 DK DK02793067T patent/DK1456224T3/da active
- 2002-12-18 EP EP02793067A patent/EP1456224B1/en not_active Expired - Lifetime
- 2002-12-18 PT PT02793067T patent/PT1456224E/pt unknown
- 2002-12-18 DE DE60209149T patent/DE60209149T2/de not_active Expired - Lifetime
- 2002-12-23 US US10/326,262 patent/US7067683B2/en not_active Expired - Fee Related
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