JP2005515778A5 - - Google Patents
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- Publication number
- JP2005515778A5 JP2005515778A5 JP2003564211A JP2003564211A JP2005515778A5 JP 2005515778 A5 JP2005515778 A5 JP 2005515778A5 JP 2003564211 A JP2003564211 A JP 2003564211A JP 2003564211 A JP2003564211 A JP 2003564211A JP 2005515778 A5 JP2005515778 A5 JP 2005515778A5
- Authority
- JP
- Japan
- Prior art keywords
- organism
- tissue
- nucleic acid
- target nucleic
- acid prepared
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000036826 Excretion Effects 0.000 claims 2
- 230000029142 excretion Effects 0.000 claims 2
- 239000012530 fluid Substances 0.000 claims 2
- 150000007523 nucleic acids Chemical class 0.000 claims 2
- 108020004707 nucleic acids Proteins 0.000 claims 2
- 210000001519 tissues Anatomy 0.000 claims 2
- 201000011510 cancer Diseases 0.000 claims 1
- 230000010094 cellular senescence Effects 0.000 claims 1
Claims (2)
- 生物体から得られた組織または身体排泄物もしくは液から調製された該標的核酸を含む試料を用いて該生物体における癌を診断するための請求項18記載の方法。
- 生物体から得られた組織または身体排泄物もしくは液から調製された該標的核酸を含む試料を用いて該生物体における細胞老化を診断するための請求項18記載の方法。
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US35359102P | 2002-01-31 | 2002-01-31 | |
PCT/US2003/002844 WO2003064615A2 (en) | 2002-01-31 | 2003-01-31 | Amplifying repetitive nucleic acid sequences |
Publications (3)
Publication Number | Publication Date |
---|---|
JP2005515778A JP2005515778A (ja) | 2005-06-02 |
JP2005515778A5 true JP2005515778A5 (ja) | 2006-03-23 |
JP4515767B2 JP4515767B2 (ja) | 2010-08-04 |
Family
ID=27663226
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2003564211A Expired - Fee Related JP4515767B2 (ja) | 2002-01-31 | 2003-01-31 | 非標的核酸依存性増幅の低減:反復核酸配列の増幅 |
Country Status (10)
Country | Link |
---|---|
US (2) | US7695904B2 (ja) |
EP (1) | EP1476561B1 (ja) |
JP (1) | JP4515767B2 (ja) |
CN (1) | CN100473723C (ja) |
AT (1) | ATE534746T1 (ja) |
AU (1) | AU2003208902B2 (ja) |
CA (1) | CA2474468C (ja) |
ES (1) | ES2379375T3 (ja) |
HK (1) | HK1072275A1 (ja) |
WO (1) | WO2003064615A2 (ja) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1585974B1 (en) * | 2003-01-24 | 2013-02-27 | University of Utah | Methods of predicting mortality risk by determining telomere length |
US8084443B2 (en) | 2007-10-01 | 2011-12-27 | Longhorn Vaccines & Diagnostics Llc | Biological specimen collection and transport system and methods of use |
US9481912B2 (en) | 2006-09-12 | 2016-11-01 | Longhorn Vaccines And Diagnostics, Llc | Compositions and methods for detecting and identifying nucleic acid sequences in biological samples |
US8097419B2 (en) | 2006-09-12 | 2012-01-17 | Longhorn Vaccines & Diagnostics Llc | Compositions and method for rapid, real-time detection of influenza A virus (H1N1) swine 2009 |
US8652782B2 (en) * | 2006-09-12 | 2014-02-18 | Longhorn Vaccines & Diagnostics, Llc | Compositions and methods for detecting, identifying and quantitating mycobacterial-specific nucleic acids |
US8080645B2 (en) | 2007-10-01 | 2011-12-20 | Longhorn Vaccines & Diagnostics Llc | Biological specimen collection/transport compositions and methods |
US9683256B2 (en) | 2007-10-01 | 2017-06-20 | Longhorn Vaccines And Diagnostics, Llc | Biological specimen collection and transport system |
US11041215B2 (en) | 2007-08-24 | 2021-06-22 | Longhorn Vaccines And Diagnostics, Llc | PCR ready compositions and methods for detecting and identifying nucleic acid sequences |
CA2697373C (en) | 2007-08-27 | 2019-05-21 | Longhorn Vaccines & Diagnostics, Llc | Immunogenic compositions and methods |
US10004799B2 (en) | 2007-08-27 | 2018-06-26 | Longhorn Vaccines And Diagnostics, Llc | Composite antigenic sequences and vaccines |
US11041216B2 (en) | 2007-10-01 | 2021-06-22 | Longhorn Vaccines And Diagnostics, Llc | Compositions and methods for detecting and quantifying nucleic acid sequences in blood samples |
CN101230403B (zh) * | 2008-02-21 | 2010-12-29 | 浙江理工大学 | 解析染色体端粒g-末端序列的方法 |
EP2342360B1 (en) | 2008-10-17 | 2016-01-06 | Geron Corporation | Method for identification of sensitivity of a patient to telomerase inhibition therapy |
CN107083444B (zh) | 2008-12-22 | 2023-03-14 | 犹他大学研究基金会 | 单色多重定量pcr |
US20110207128A1 (en) * | 2010-02-16 | 2011-08-25 | Cawthon Richard M | Methods and kits for determining biological age and longevity based on gene expression profiles |
JP2011223940A (ja) * | 2010-04-21 | 2011-11-10 | Asahi Breweries Ltd | 偽陰性を排除するpcr検査方法およびそれに使用するプライマー |
JP6273198B2 (ja) | 2011-03-28 | 2018-01-31 | ジェロン・コーポレーションGeron Corporation | 定量的pcrによる、ホルマリン固定パラフィン包埋(ffpe)試料におけるテロメア長測定 |
JP5288387B1 (ja) * | 2011-10-13 | 2013-09-11 | 学校法人東京女子医科大学 | テロメア配列増幅用プライマー |
WO2013101290A1 (en) * | 2011-12-29 | 2013-07-04 | Qiagen | Methods of using telomeres as markers for aging |
WO2013112916A1 (en) | 2012-01-26 | 2013-08-01 | Longhorn Vaccines And Diagnostics, Llc | Composite antigenic sequences and vaccines |
US20130310269A1 (en) * | 2012-05-04 | 2013-11-21 | Austin So | Hot-start digital pcr |
US9200327B2 (en) | 2012-11-30 | 2015-12-01 | Geron Corporation | Diagnostic markers for treating cell proliferative disorders with telomerase inhibitors |
KR102174763B1 (ko) | 2012-11-30 | 2020-11-06 | 제론 코포레이션 | 텔로머라제 억제자로 세포 증식성 질환 치료용 진단 마커 |
EP2971154A4 (en) * | 2013-03-14 | 2017-03-01 | Ibis Biosciences, Inc. | Nucleic acid control panels |
US10093970B2 (en) | 2013-03-15 | 2018-10-09 | New York University | Method for single cell analysis of telomere length using pre-amplification and multiple-copy reference sequence |
JP2016512696A (ja) * | 2013-03-15 | 2016-05-09 | アーノルド, ライル, ジェイ.ARNOLD, Lyle, J. | アセンブラ配列を利用する断片化された標的核酸の増幅方法 |
CA2912216A1 (en) | 2013-05-22 | 2014-11-27 | Telomere Diagnostics, Inc. | Measures of short telomere abundance |
GB201418144D0 (en) * | 2014-10-14 | 2014-11-26 | Univ Cardiff | High throughput sequencing |
JP2018501799A (ja) * | 2014-12-30 | 2018-01-25 | テロメア ダイアグノスティクス インコーポレイテッド | マルチプレックス定量的pcr |
WO2016183292A1 (en) | 2015-05-14 | 2016-11-17 | Longhorn Vaccines And Diagnostics, Llc | Rapid methods for the extraction of nucleic acids from biological samples |
US10577643B2 (en) * | 2015-10-07 | 2020-03-03 | Illumina, Inc. | Off-target capture reduction in sequencing techniques |
US10186789B1 (en) | 2018-04-13 | 2019-01-22 | Rustcraft Industries LLC | Keyed cable and connector system |
CN112029841B (zh) | 2019-06-03 | 2024-02-09 | 香港中文大学 | 定量端粒长度和基因组基序的方法 |
CN113862339B (zh) * | 2021-12-01 | 2022-03-22 | 广州滴纳生物科技有限公司 | 核酸组合产品、检测试剂盒和扩增靶核酸的方法 |
CN117230169B (zh) * | 2023-11-13 | 2024-02-13 | 元码基因科技(北京)股份有限公司 | 用于长片段端粒序列测序的接头、预文库及其构建方法 |
CN117248003B (zh) * | 2023-11-13 | 2024-04-12 | 元码基因科技(北京)股份有限公司 | 用于完整端粒扩增子测序的组合物、预文库及其构建方法 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6020124A (en) | 1992-04-27 | 2000-02-01 | Trustees Of Dartmouth College | Detection of soluble gene sequences in biological fluids |
US5489508A (en) | 1992-05-13 | 1996-02-06 | University Of Texas System Board Of Regents | Therapy and diagnosis of conditions related to telomere length and/or telomerase activity |
US5512441A (en) * | 1994-11-15 | 1996-04-30 | American Health Foundation | Quantative method for early detection of mutant alleles and diagnostic kits for carrying out the method |
US5741677A (en) | 1995-06-07 | 1998-04-21 | Geron Corporation | Methods for measuring telomere length |
JP3718892B2 (ja) * | 1996-02-05 | 2005-11-24 | 三菱化学株式会社 | ヒト・テロメラーゼ活性の測定方法 |
JP4013333B2 (ja) | 1998-06-05 | 2007-11-28 | 株式会社B&Cラボラトリーズ | 皮膚の老化度の測定方法および測定用キット |
US6436677B1 (en) * | 2000-03-02 | 2002-08-20 | Promega Corporation | Method of reverse transcription |
-
2003
- 2003-01-31 AT AT03707624T patent/ATE534746T1/de active
- 2003-01-31 JP JP2003564211A patent/JP4515767B2/ja not_active Expired - Fee Related
- 2003-01-31 CN CNB038048671A patent/CN100473723C/zh not_active Expired - Fee Related
- 2003-01-31 ES ES03707624T patent/ES2379375T3/es not_active Expired - Lifetime
- 2003-01-31 EP EP03707624A patent/EP1476561B1/en not_active Expired - Lifetime
- 2003-01-31 CA CA2474468A patent/CA2474468C/en not_active Expired - Lifetime
- 2003-01-31 AU AU2003208902A patent/AU2003208902B2/en not_active Ceased
- 2003-01-31 WO PCT/US2003/002844 patent/WO2003064615A2/en active Application Filing
- 2003-01-31 US US10/355,626 patent/US7695904B2/en active Active
-
2005
- 2005-04-26 HK HK05103554.7A patent/HK1072275A1/xx not_active IP Right Cessation
-
2010
- 2010-02-04 US US12/700,475 patent/US8048631B2/en not_active Expired - Fee Related
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