JP2005515244A5 - - Google Patents
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- Publication number
- JP2005515244A5 JP2005515244A5 JP2003561613A JP2003561613A JP2005515244A5 JP 2005515244 A5 JP2005515244 A5 JP 2005515244A5 JP 2003561613 A JP2003561613 A JP 2003561613A JP 2003561613 A JP2003561613 A JP 2003561613A JP 2005515244 A5 JP2005515244 A5 JP 2005515244A5
- Authority
- JP
- Japan
- Prior art keywords
- active ingredient
- leishmaniasis
- miltefosine
- perifosine
- dose
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000004480 active ingredient Substances 0.000 claims 16
- 239000003814 drug Substances 0.000 claims 14
- PQLXHQMOHUQAKB-UHFFFAOYSA-N miltefosine Chemical compound CCCCCCCCCCCCCCCCOP([O-])(=O)OCC[N+](C)(C)C PQLXHQMOHUQAKB-UHFFFAOYSA-N 0.000 claims 13
- 229960003775 miltefosine Drugs 0.000 claims 13
- SZFPYBIJACMNJV-UHFFFAOYSA-N perifosine Chemical compound CCCCCCCCCCCCCCCCCCOP([O-])(=O)OC1CC[N+](C)(C)CC1 SZFPYBIJACMNJV-UHFFFAOYSA-N 0.000 claims 8
- 229950010632 perifosine Drugs 0.000 claims 8
- 208000004554 Leishmaniasis Diseases 0.000 claims 5
- 238000012423 maintenance Methods 0.000 claims 4
- 238000011321 prophylaxis Methods 0.000 claims 4
- 241000124008 Mammalia Species 0.000 claims 3
- 208000015181 infectious disease Diseases 0.000 claims 3
- 206010011668 Cutaneous leishmaniasis Diseases 0.000 claims 2
- 206010047505 Visceral leishmaniasis Diseases 0.000 claims 2
- 230000003474 anti-emetic effect Effects 0.000 claims 2
- 229940125714 antidiarrheal agent Drugs 0.000 claims 2
- 239000003793 antidiarrheal agent Substances 0.000 claims 2
- 239000002111 antiemetic agent Substances 0.000 claims 2
- 229940125683 antiemetic agent Drugs 0.000 claims 2
- 201000000626 mucocutaneous leishmaniasis Diseases 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 229910019142 PO4 Inorganic materials 0.000 claims 1
- 230000037396 body weight Effects 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 claims 1
- 239000010452 phosphate Substances 0.000 claims 1
- 229920006395 saturated elastomer Polymers 0.000 claims 1
- 238000009738 saturating Methods 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10203195A DE10203195A1 (de) | 2002-01-25 | 2002-01-25 | Verwendung von Alkylphosphocholinen in der Präventivbehandlung von Protozoenerkrankungen |
| PCT/EP2003/000072 WO2003061669A1 (de) | 2002-01-25 | 2003-01-07 | Verwendung von alkylphosphocholinen in der präventivbehandlung von protozoenerkrankungen |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005515244A JP2005515244A (ja) | 2005-05-26 |
| JP2005515244A5 true JP2005515244A5 (https=) | 2006-01-05 |
Family
ID=7713213
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003561613A Pending JP2005515244A (ja) | 2002-01-25 | 2003-01-07 | 原虫症の予防的処置のためのアルキルホスホコリンの使用 |
Country Status (16)
| Country | Link |
|---|---|
| EP (1) | EP1467742A1 (https=) |
| JP (1) | JP2005515244A (https=) |
| CN (1) | CN1622811A (https=) |
| AR (1) | AR038224A1 (https=) |
| AU (1) | AU2003236787B2 (https=) |
| BR (1) | BR0307021A (https=) |
| CA (1) | CA2470185A1 (https=) |
| CO (1) | CO5601024A2 (https=) |
| DE (1) | DE10203195A1 (https=) |
| IL (2) | IL162492A0 (https=) |
| MX (1) | MXPA04007193A (https=) |
| NZ (1) | NZ548040A (https=) |
| PE (1) | PE20030732A1 (https=) |
| TW (1) | TWI339582B (https=) |
| WO (1) | WO2003061669A1 (https=) |
| ZA (1) | ZA200404690B (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT501545B1 (de) * | 2005-02-23 | 2007-10-15 | Obwaller Andreas Dr | Reinigungsmittel für kontaktlinsen |
| CA2632449A1 (en) * | 2005-12-19 | 2007-06-28 | Aeterna Zentaris Gmbh | Alkyl phospholipid derivatives with reduced cytotoxicity and uses thereof |
| EP1800684A1 (en) * | 2005-12-20 | 2007-06-27 | Zentaris GmbH | Novel alkyl phospholipid derivatives and uses thereof |
| CN104473941A (zh) * | 2014-12-20 | 2015-04-01 | 长沙佰顺生物科技有限公司 | 一种含有米替福新的药物制剂及其制备方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4132345A1 (de) * | 1991-09-27 | 1993-04-01 | Max Planck Gesellschaft | Ether-lysolecithine und alkylphosphocholine in liposomen |
| DE4132344A1 (de) * | 1991-09-27 | 1993-04-01 | Max Planck Gesellschaft | Verfahren zur herstellung eines arzneimittels zur oralen oder topischen verabreichung bei der behandlung von leishmaniasis |
| BR9306040A (pt) * | 1992-03-06 | 1997-11-18 | Statens Seruminstitut | Tratamento e profilaxia de doenças provocadas por parasitos ou bactérias |
| ES2175663T3 (es) * | 1998-01-22 | 2002-11-16 | Zentaris Ag | Composiciones farmaceuticas solidas que contienen miltefosina para administracion oral en el tratamiento de la leshmaniasis. |
| DE10020812C2 (de) * | 2000-04-20 | 2003-06-26 | Robert Koch Inst | Verwendung von Naphthindazol-4,9-chinonen als Antiparasitika |
| AU2002232400A1 (en) * | 2000-11-06 | 2002-05-15 | U.S. Army Medical Research And Materiel Command | Reversed amidines and methods of using for treating, preventing, or inhibiting leishmaniasis |
-
2002
- 2002-01-25 DE DE10203195A patent/DE10203195A1/de not_active Withdrawn
-
2003
- 2003-01-07 IL IL16249203A patent/IL162492A0/xx unknown
- 2003-01-07 CN CNA038027062A patent/CN1622811A/zh active Pending
- 2003-01-07 CA CA002470185A patent/CA2470185A1/en not_active Abandoned
- 2003-01-07 EP EP03731619A patent/EP1467742A1/de not_active Ceased
- 2003-01-07 JP JP2003561613A patent/JP2005515244A/ja active Pending
- 2003-01-07 AU AU2003236787A patent/AU2003236787B2/en not_active Expired
- 2003-01-07 MX MXPA04007193A patent/MXPA04007193A/es active IP Right Grant
- 2003-01-07 WO PCT/EP2003/000072 patent/WO2003061669A1/de not_active Ceased
- 2003-01-07 NZ NZ548040A patent/NZ548040A/en not_active IP Right Cessation
- 2003-01-07 BR BR0307021-2A patent/BR0307021A/pt not_active Application Discontinuation
- 2003-01-13 TW TW092100614A patent/TWI339582B/zh not_active IP Right Cessation
- 2003-01-20 PE PE2003000061A patent/PE20030732A1/es not_active Application Discontinuation
- 2003-01-24 AR ARP030100214A patent/AR038224A1/es unknown
-
2004
- 2004-06-14 ZA ZA200404690A patent/ZA200404690B/en unknown
- 2004-06-14 IL IL162492A patent/IL162492A/en active IP Right Grant
- 2004-07-23 CO CO04070642A patent/CO5601024A2/es not_active Application Discontinuation
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