JP2005514071A5 - - Google Patents
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- Publication number
- JP2005514071A5 JP2005514071A5 JP2003560222A JP2003560222A JP2005514071A5 JP 2005514071 A5 JP2005514071 A5 JP 2005514071A5 JP 2003560222 A JP2003560222 A JP 2003560222A JP 2003560222 A JP2003560222 A JP 2003560222A JP 2005514071 A5 JP2005514071 A5 JP 2005514071A5
- Authority
- JP
- Japan
- Prior art keywords
- stem cells
- cells
- vector
- progenitor
- monolayer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 claims 16
- 210000000130 stem cell Anatomy 0.000 claims 12
- 239000002609 medium Substances 0.000 claims 4
- 102100031573 Hematopoietic progenitor cell antigen CD34 Human genes 0.000 claims 3
- 101000777663 Homo sapiens Hematopoietic progenitor cell antigen CD34 Proteins 0.000 claims 3
- 239000002356 single layer Substances 0.000 claims 3
- 230000026683 transduction Effects 0.000 claims 3
- 238000010361 transduction Methods 0.000 claims 3
- 102100031585 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 Human genes 0.000 claims 2
- 102000004127 Cytokines Human genes 0.000 claims 2
- 108090000695 Cytokines Proteins 0.000 claims 2
- 101000777636 Homo sapiens ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 Proteins 0.000 claims 2
- 210000004556 brain Anatomy 0.000 claims 2
- 210000002889 endothelial cell Anatomy 0.000 claims 2
- 230000003394 haemopoietic effect Effects 0.000 claims 2
- 108010017213 Granulocyte-Macrophage Colony-Stimulating Factor Proteins 0.000 claims 1
- 102100039620 Granulocyte-macrophage colony-stimulating factor Human genes 0.000 claims 1
- 102000000646 Interleukin-3 Human genes 0.000 claims 1
- 108010002386 Interleukin-3 Proteins 0.000 claims 1
- 102000004889 Interleukin-6 Human genes 0.000 claims 1
- 108090001005 Interleukin-6 Proteins 0.000 claims 1
- 241000700605 Viruses Species 0.000 claims 1
- 210000001185 bone marrow Anatomy 0.000 claims 1
- 210000004027 cell Anatomy 0.000 claims 1
- 210000004700 fetal blood Anatomy 0.000 claims 1
- 108700014844 flt3 ligand Proteins 0.000 claims 1
- 239000001963 growth medium Substances 0.000 claims 1
- 238000000338 in vitro Methods 0.000 claims 1
- 229940076264 interleukin-3 Drugs 0.000 claims 1
- 229940100601 interleukin-6 Drugs 0.000 claims 1
- 238000002955 isolation Methods 0.000 claims 1
- 208000032839 leukemia Diseases 0.000 claims 1
- 210000004925 microvascular endothelial cell Anatomy 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 230000001177 retroviral effect Effects 0.000 claims 1
- 230000002463 transducing effect Effects 0.000 claims 1
- 210000003556 vascular endothelial cell Anatomy 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US34186801P | 2001-12-21 | 2001-12-21 | |
| PCT/US2002/040719 WO2003060138A1 (en) | 2001-12-21 | 2002-12-20 | In increasing gene transfer efficiency by pre-incubation with endothelial cells |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005514071A JP2005514071A (ja) | 2005-05-19 |
| JP2005514071A5 true JP2005514071A5 (https=) | 2006-04-13 |
Family
ID=23339354
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003560222A Pending JP2005514071A (ja) | 2001-12-21 | 2002-12-20 | 内皮細胞との前培養による遺伝子導入効率の上昇 |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP1463821A4 (https=) |
| JP (1) | JP2005514071A (https=) |
| AU (1) | AU2002360674A1 (https=) |
| WO (1) | WO2003060138A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE602006014814D1 (de) * | 2005-04-21 | 2010-07-22 | Massachusetts Inst Technology | Materialien und verfahren zur änderung einer immunreaktion auf exogene und endogene immunogene, einschliesslich genidentischer und nicht-genidentischer zellen, gewebe oder organe |
| CN101735979B (zh) * | 2009-12-31 | 2014-04-30 | 浙江中赢控股集团有限公司 | 体外扩增造血干细胞和前体细胞的方法 |
| ES2747951T3 (es) * | 2013-10-24 | 2020-03-12 | Ospedale San Raffaele Srl | Método |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5811297A (en) * | 1996-03-07 | 1998-09-22 | Amba Biosciences, Llc | Immortalized hematopoietic cell lines, cell system thereof with stromal cells, in vitro, ex vivo and in vivo uses, & in vitro generation of dendritic cells and macrophages |
| JP2004523202A (ja) * | 2000-06-09 | 2004-08-05 | ウニベルジテートスクリーニクム シャリテー メディツィニーシェ ファクルテート デル フンボルト−ウニベルジテート ツー ベルリン，アカデミッシェ ファーバルツング−フォルシュン | 遺伝子修飾ｔ細胞、該細胞の製造方法および該細胞の使用 |
| WO2002078449A2 (en) * | 2001-04-02 | 2002-10-10 | Advanced Cell Technology, Inc. | Method for facilitating the production of differentiated cell types and tissues from embryonic and adult pluripotent and multipotent cells |
-
2002
- 2002-12-20 AU AU2002360674A patent/AU2002360674A1/en not_active Abandoned
- 2002-12-20 EP EP02795952A patent/EP1463821A4/en not_active Withdrawn
- 2002-12-20 WO PCT/US2002/040719 patent/WO2003060138A1/en not_active Ceased
- 2002-12-20 JP JP2003560222A patent/JP2005514071A/ja active Pending
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