JP2005511748A5 - - Google Patents
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- Publication number
- JP2005511748A5 JP2005511748A5 JP2003551152A JP2003551152A JP2005511748A5 JP 2005511748 A5 JP2005511748 A5 JP 2005511748A5 JP 2003551152 A JP2003551152 A JP 2003551152A JP 2003551152 A JP2003551152 A JP 2003551152A JP 2005511748 A5 JP2005511748 A5 JP 2005511748A5
- Authority
- JP
- Japan
- Prior art keywords
- prior
- art
- compounds described
- compounds
- phosphodiesterases
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 150000001875 compounds Chemical class 0.000 description 3
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 102000004861 Phosphoric Diester Hydrolases Human genes 0.000 description 1
- 108090001050 Phosphoric Diester Hydrolases Proteins 0.000 description 1
- 210000001744 T-lymphocyte Anatomy 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000002209 hydrophobic effect Effects 0.000 description 1
- 239000003446 ligand Substances 0.000 description 1
- UEZVMMHDMIWARA-UHFFFAOYSA-M phosphonate Chemical compound [O-]P(=O)=O UEZVMMHDMIWARA-UHFFFAOYSA-M 0.000 description 1
- 230000035755 proliferation Effects 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0115971A FR2833266B1 (fr) | 2001-12-11 | 2001-12-11 | Nouveaux derives phosphonates, leur procede de preparation, leur utilisation comme modulateurs de l'activite des lymphocytes tgamma9 delta2 |
| PCT/FR2002/004190 WO2003050128A1 (fr) | 2001-12-11 | 2002-12-05 | PHOSPHONATES UTILES COMME MODULATEURS DE L'ACTIVITE DES LYMPHOCYTES t-GAMMA-9-DELTA-2 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005511748A JP2005511748A (ja) | 2005-04-28 |
| JP2005511748A5 true JP2005511748A5 (enExample) | 2010-04-08 |
Family
ID=8870319
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003551152A Pending JP2005511748A (ja) | 2001-12-11 | 2002-12-05 | T−ガンマ−9−デルタ−2リンパ球の活性のモジュレーターとして有用なホスホネート |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US20060241087A1 (enExample) |
| EP (1) | EP1453840A1 (enExample) |
| JP (1) | JP2005511748A (enExample) |
| AU (1) | AU2002366577A1 (enExample) |
| FR (1) | FR2833266B1 (enExample) |
| WO (1) | WO2003050128A1 (enExample) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0212666D0 (en) * | 2002-05-31 | 2002-07-10 | Secr Defence | Immunogenic sequences |
| BRPI0417088A (pt) * | 2003-12-02 | 2007-03-13 | Innate Pharma | ativador de célula t gama delta, composição farmacêutica, uso do ativador de célula t gama delta, composição de vacina, métodos para preparar um composto, e para ativar uma célula t gama delta, célula t gama delta, e, uso da mesma |
| US20070134273A1 (en) * | 2004-02-10 | 2007-06-14 | Francois Romagne | Composition and method for the treatment of carcinoma |
| US20070218086A1 (en) * | 2004-04-26 | 2007-09-20 | Innate Pharma, S.A. | Adjuvant Composition and Methods for Its Use |
| WO2006067635A2 (en) * | 2004-12-20 | 2006-06-29 | Innate Pharma S.A. | USE OF Ϝδ T LYMPHOCYTE ACTIVATORS AS VACCINE ADJUVANT |
| BRPI0608926A2 (pt) * | 2005-03-22 | 2010-11-03 | Innate Pharma | ativador de células t gamadelta, composição farmacêutica, uso de um ativador de células t gamadelta, composição de vacina, método de ativação de uma célula t gamadelta, célula t gamadelta, e, uso de uma célula t gamadelta |
| GB2443591B (en) * | 2005-09-07 | 2010-04-28 | Secr Defence | Adjuvanted vaccine |
| WO2007039635A2 (en) * | 2005-10-06 | 2007-04-12 | Innate Pharma | Phosphoantigen salts of organic bases and methods for their crystallization |
| WO2008012538A2 (en) | 2006-07-25 | 2008-01-31 | The Secretary Of State For Defence | Live vaccine strains of francisella |
| EP2083830A1 (en) | 2006-11-17 | 2009-08-05 | Innate Pharma | Improved methods of using phosphoantigen for the treatment of cancer |
| GB0906234D0 (en) | 2009-04-14 | 2009-05-20 | Secr Defence | Vaccine |
| CN111432891B (zh) | 2017-12-11 | 2024-01-02 | 宝洁公司 | 含膦酰基-磷酸根基团和阴离子基团的聚合物 |
| EP3723701B1 (en) | 2017-12-11 | 2025-08-06 | The Procter & Gamble Company | Method of making phosphono-phosphate containing compounds |
| WO2019118419A1 (en) * | 2017-12-11 | 2019-06-20 | The Procter & Gamble Company | Compositions comprising multi-valent cations and phosphono-phosphate containing polymers |
| WO2019118416A1 (en) * | 2017-12-11 | 2019-06-20 | The Procter & Gamble Company | Phosphono-phosphate containing compounds and polymers |
| MX391985B (es) * | 2017-12-11 | 2025-03-21 | Procter & Gamble | Composiciones para el cuidado bucal que comprenden polimeros que contienen grupo fosfono-fosfato y anionico |
| MX390467B (es) | 2017-12-11 | 2025-03-20 | Procter & Gamble | Composiciones para el cuidado bucal que comprenden polimeros que contienen grupos fosfonato y anionicos |
| JP7065513B2 (ja) * | 2018-06-29 | 2022-05-12 | 国立研究開発法人産業技術総合研究所 | 有機リン化合物 |
| EP3856206A1 (en) | 2018-09-27 | 2021-08-04 | Phosphogam, Inc. | Methods and compositions for the expansion and use of allogeneic gamma/delta-t cells |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR6914868D0 (pt) * | 1969-01-23 | 1973-03-20 | & Co Inc Merck | Processos quimicos |
| ZA774977B (en) * | 1976-09-06 | 1978-06-28 | Sab Soc Etudes Applic Biolog | Process for the preparation of 1,2-expoxypropyl-phosphonic acid derivatives |
| US4924024A (en) * | 1988-01-11 | 1990-05-08 | E. R. Squibb & Sons, Inc. | Phosphorus-containing squalene synthetase inhibitors, new intermediates and method |
| US5177239A (en) * | 1989-07-18 | 1993-01-05 | E. R. Squibb & Sons, Inc. | Method for preparing a phosphonic acid ester |
| US5298655A (en) * | 1991-09-27 | 1994-03-29 | Merck & Co., Inc. | Farnesyl pyrophosphate analogs |
| US5827838A (en) * | 1992-10-06 | 1998-10-27 | Nederlandse Organisatie Voor Toegepast-Natuurwetenschappelijk Onderzoek Tno & Rijksuniversteit Te Leiden | Method for the treatment of diseases related with protein isoprenylation |
| US5463181A (en) * | 1993-02-23 | 1995-10-31 | Merrell Dow Pharmaceuticals Inc. | Farnesyl: protein transferase inhibitors as anticancer agents |
| WO1994019357A1 (en) * | 1993-02-23 | 1994-09-01 | Merrell Dow Pharmaceuticals Inc. | Farnesyl:protein transferase inhibitors as anticancer agents |
| US5574025A (en) * | 1994-10-26 | 1996-11-12 | Merck & Co., Inc. | Inhibitors of prenyl-protein transferases |
| IT1276162B1 (it) * | 1995-11-23 | 1997-10-27 | Baldacci Lab Spa | Geranilgeranil-derivati,procedimento per la loro preparazione e relative composizioni farmaceutiche |
| FR2782721B1 (fr) * | 1998-09-01 | 2000-11-03 | Inst Nat Sante Rech Med | Nouveaux composes phosphohalohydrines, procede de fabrication et applications |
| FR2782722B1 (fr) * | 1998-09-01 | 2001-01-12 | Inst Nat Sante Rech Med | Nouveaux composes phosphoepoxydes, procede de fabrication et applications |
| JP4025019B2 (ja) * | 1999-01-21 | 2007-12-19 | 中外製薬株式会社 | 2−メチル−3−ブテニル−1−ピロリン酸の塩およびリンパ球処理剤 |
| FR2791981B1 (fr) * | 1999-04-06 | 2001-07-20 | Inst Nat Sante Rech Med | Composes inhibant selectivement les lymphocytes tgamma9delta2, et leurs applications |
| EP1169996A1 (de) * | 2000-07-06 | 2002-01-09 | Ernst Mühlbauer Kg | Phosphonsäuren enthaltendes Dentalmaterial |
| DE10201458A1 (de) | 2001-04-11 | 2002-10-17 | Adelbert Bacher | Intermediate und Enzyme des Mevalonat-unabhängigen Isoprenoidbiosyntheseweg |
| WO2003009855A2 (de) * | 2001-07-20 | 2003-02-06 | Bioagency Ag | Organo-phosphorverbindungen zur aktivierung von gamma/delta-t-zellen |
-
2001
- 2001-12-11 FR FR0115971A patent/FR2833266B1/fr not_active Expired - Fee Related
-
2002
- 2002-12-05 WO PCT/FR2002/004190 patent/WO2003050128A1/fr not_active Ceased
- 2002-12-05 AU AU2002366577A patent/AU2002366577A1/en not_active Abandoned
- 2002-12-05 JP JP2003551152A patent/JP2005511748A/ja active Pending
- 2002-12-05 EP EP02804596A patent/EP1453840A1/fr not_active Ceased
- 2002-12-05 US US10/498,313 patent/US20060241087A1/en not_active Abandoned
-
2010
- 2010-01-14 US US12/656,049 patent/US8017596B2/en not_active Expired - Fee Related
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