JP2005511644A - 核酸およびカチオン性アミノグリコシドの組成物ならびにそれを使用および調製する方法 - Google Patents

核酸およびカチオン性アミノグリコシドの組成物ならびにそれを使用および調製する方法 Download PDF

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JP2005511644A
JP2005511644A JP2003547414A JP2003547414A JP2005511644A JP 2005511644 A JP2005511644 A JP 2005511644A JP 2003547414 A JP2003547414 A JP 2003547414A JP 2003547414 A JP2003547414 A JP 2003547414A JP 2005511644 A JP2005511644 A JP 2005511644A
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nucleic acid
composition
cationic
aminoglycoside
cell
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Japanese (ja)
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JP2005511644A5 (OSRAM
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イゴール ゴンダ
ディーパ デッシュパンデ
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アラダイム コーポレーション
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2003547414A 2001-11-21 2002-11-15 核酸およびカチオン性アミノグリコシドの組成物ならびにそれを使用および調製する方法 Pending JP2005511644A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/990,181 US20030096774A1 (en) 2001-11-21 2001-11-21 Compositions of nucleic acids and cationic aminoglycosides and methods of using and preparing the same
PCT/US2002/036529 WO2003045965A2 (en) 2001-11-21 2002-11-15 Compositions of nucleic acids and cationic aminoglycosides and methods of using and preparing the same

Publications (2)

Publication Number Publication Date
JP2005511644A true JP2005511644A (ja) 2005-04-28
JP2005511644A5 JP2005511644A5 (OSRAM) 2006-03-23

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ID=25535873

Family Applications (1)

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JP2003547414A Pending JP2005511644A (ja) 2001-11-21 2002-11-15 核酸およびカチオン性アミノグリコシドの組成物ならびにそれを使用および調製する方法

Country Status (6)

Country Link
US (2) US20030096774A1 (OSRAM)
EP (1) EP1453845A4 (OSRAM)
JP (1) JP2005511644A (OSRAM)
AU (1) AU2002363928A1 (OSRAM)
CA (1) CA2467677A1 (OSRAM)
WO (1) WO2003045965A2 (OSRAM)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009536612A (ja) * 2006-04-06 2009-10-15 トランセイブ， インク． 脂質を用いた薬物製剤の高速送達とその処置方法
WO2016025627A1 (en) * 2014-08-12 2016-02-18 The Regents Of The University Of California Multifunctional membrane-active aminoglycoside-peptide conjugates

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US20060165606A1 (en) 1997-09-29 2006-07-27 Nektar Therapeutics Pulmonary delivery particles comprising water insoluble or crystalline active agents
US8404217B2 (en) 2000-05-10 2013-03-26 Novartis Ag Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use
US7871598B1 (en) 2000-05-10 2011-01-18 Novartis Ag Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
US7368102B2 (en) 2001-12-19 2008-05-06 Nektar Therapeutics Pulmonary delivery of aminoglycosides
WO2003075889A1 (en) * 2002-03-05 2003-09-18 Transave, Inc. An inhalation system for prevention and treatment of intracellular infections
US7718189B2 (en) * 2002-10-29 2010-05-18 Transave, Inc. Sustained release of antiinfectives
KR101301653B1 (ko) * 2002-10-29 2013-08-30 트랜세이브, 인코포레이티드 항감염제의 지속적인 방출
WO2005060573A2 (en) * 2003-12-15 2005-07-07 University Of Medicine And Dentistry Of New Jersey Pna-neamine conjugates and methods for producing and using the same
US20080226605A1 (en) * 2005-05-19 2008-09-18 Dev Priya Arya Methods and Compositions Facilitating Entry of Compounds Into Cells
JP5324223B2 (ja) 2005-12-08 2013-10-23 トランセイブ， インク． 肺感染症を治療する抗感染薬の脂質ベースの組成物及びその使用法
CN101646462A (zh) 2007-03-30 2010-02-10 大塚制药株式会社 药物转运控制用经肺给药脂质体
US20100196455A1 (en) 2007-05-04 2010-08-05 Transave, Inc. Compositions of Multicationic Drugs for Reducing Interactions with Polyanionic Biomolecules and Methods of Use Thereof
US9333214B2 (en) 2007-05-07 2016-05-10 Insmed Incorporated Method for treating pulmonary disorders with liposomal amikacin formulations
US9119783B2 (en) 2007-05-07 2015-09-01 Insmed Incorporated Method of treating pulmonary disorders with liposomal amikacin formulations
US9114081B2 (en) 2007-05-07 2015-08-25 Insmed Incorporated Methods of treating pulmonary disorders with liposomal amikacin formulations
US9271933B2 (en) * 2007-11-27 2016-03-01 Rutgers, The State University Of New Jersey Graft copolymer polyelectrolyte complexes for drug delivery
US9789194B2 (en) 2007-11-27 2017-10-17 Rutgers, The State University Of New Jersey Graft copolymer polyelectrolyte complexes for drug delivery
US8979797B2 (en) * 2010-12-16 2015-03-17 Ams Research Corporation High pressure delivery system and method for treating pelvic disorder using large molecule therapeutics
PL2852391T3 (pl) 2012-05-21 2022-04-11 Insmed Incorporated Układy do leczenia infekcji płuc
MX2015006681A (es) 2012-11-29 2016-04-06 Insmed Inc Formulaciones de vancomicina estabilizadas.
CN103272238B (zh) * 2013-06-08 2015-04-15 北京大学 基于dna与氨基糖苷类分子复合物的生物材料
SMT202000516T1 (it) 2014-05-15 2020-11-10 Insmed Inc Metodi per trattamento di infezioni micobatteriche polmonati non tubercolari
WO2019191627A1 (en) 2018-03-30 2019-10-03 Insmed Incorporated Methods for continuous manufacture of liposomal drug products
WO2019213398A1 (en) 2018-05-02 2019-11-07 Insmed Incorporated Methods for the manufacture of liposomal drug formulations
DE102018113243A1 (de) 2018-06-04 2019-12-05 BIOCHEM Zusatzstoffe Handels- und Produktionsgesellschaft mbH Verfahren zur Herstellung einer Zusammensetzung enthaltend zumindest eine Metall-Aminosäure-Verbindung sowie Zusammensetzung erhältlich durch ein derartiges Verfahren

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Publication number Priority date Publication date Assignee Title
US4400375A (en) * 1981-11-23 1983-08-23 Eli Lilly And Company Tobramycin-double stranded RNA complex suitable for inducing interferon
US5469854A (en) * 1989-12-22 1995-11-28 Imarx Pharmaceutical Corp. Methods of preparing gas-filled liposomes
US5756353A (en) * 1991-12-17 1998-05-26 The Regents Of The University Of California Expression of cloned genes in the lung by aerosol-and liposome-based delivery
PT669929E (pt) * 1992-11-13 2007-04-30 Immunex Corp Ligando de elk, uma citoquina
US6015686A (en) * 1993-09-15 2000-01-18 Chiron Viagene, Inc. Eukaryotic layered vector initiation systems
US6070575A (en) * 1998-11-16 2000-06-06 Aradigm Corporation Aerosol-forming porous membrane with certain pore structure

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009536612A (ja) * 2006-04-06 2009-10-15 トランセイブ， インク． 脂質を用いた薬物製剤の高速送達とその処置方法
WO2016025627A1 (en) * 2014-08-12 2016-02-18 The Regents Of The University Of California Multifunctional membrane-active aminoglycoside-peptide conjugates

Also Published As

Publication number Publication date
EP1453845A4 (en) 2005-11-09
AU2002363928A8 (en) 2003-06-10
US20030096774A1 (en) 2003-05-22
AU2002363928A1 (en) 2003-06-10
WO2003045965A2 (en) 2003-06-05
US20050019926A1 (en) 2005-01-27
EP1453845A2 (en) 2004-09-08
CA2467677A1 (en) 2003-06-05
WO2003045965A3 (en) 2004-01-08

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