JP2005508983A5 - - Google Patents

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Publication number
JP2005508983A5
JP2005508983A5 JP2003541843A JP2003541843A JP2005508983A5 JP 2005508983 A5 JP2005508983 A5 JP 2005508983A5 JP 2003541843 A JP2003541843 A JP 2003541843A JP 2003541843 A JP2003541843 A JP 2003541843A JP 2005508983 A5 JP2005508983 A5 JP 2005508983A5
Authority
JP
Japan
Prior art keywords
methyl
drug
dione
rheumatic
dmard
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2003541843A
Other languages
English (en)
Japanese (ja)
Other versions
JP2005508983A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2002/012415 external-priority patent/WO2003039552A1/en
Publication of JP2005508983A publication Critical patent/JP2005508983A/ja
Publication of JP2005508983A5 publication Critical patent/JP2005508983A5/ja
Pending legal-status Critical Current

Links

JP2003541843A 2001-11-09 2002-11-07 Ｐｄｅ４又はｐｄｅ３／４阻害剤及び抗リウマチ薬の複合薬 Pending JP2005508983A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01000607 2001-11-09
PCT/EP2002/012415 WO2003039552A1 (en) 2001-11-09 2002-11-07 Combination of pde4 or pde3/4 inhibitor and an anti-rheumatic drug

Publications (2)

Publication Number Publication Date
JP2005508983A JP2005508983A (ja) 2005-04-07
JP2005508983A5 true JP2005508983A5 (https=) 2006-01-05

Family

ID=8176085

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2003541843A Pending JP2005508983A (ja) 2001-11-09 2002-11-07 Ｐｄｅ４又はｐｄｅ３／４阻害剤及び抗リウマチ薬の複合薬

Country Status (6)

Country Link
US (2) US20030092706A1 (https=)
EP (1) EP1448202A1 (https=)
JP (1) JP2005508983A (https=)
AU (1) AU2002300754B2 (https=)
CA (1) CA2399840C (https=)
WO (1) WO2003039552A1 (https=)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7718644B2 (en) * 2004-01-22 2010-05-18 The Trustees Of Columbia University In The City Of New York Anti-arrhythmic and heart failure drugs that target the leak in the ryanodine receptor (RyR2) and uses thereof
MY140561A (en) 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
PT1511516E (pt) * 2002-05-28 2009-02-20 Nycomed Gmbh Preparação farmacêutica para aplicação tópica
US6727272B1 (en) * 2002-07-15 2004-04-27 Unitech Pharmaceuticals, Inc. Leflunomide analogs for treating rheumatoid arthritis
UA82323C2 (uk) * 2002-08-09 2008-04-10 Меда Фарма Гмбх & Ко. Кг Нова комбінація глюкокортикоїду та pde-інгібітору для лікування респіраторних захворювань, алергічних захворювань, астми та хронічних обструктивних легеневих захворювань
ES2335498T3 (es) 2003-03-10 2010-03-29 Nycomed Gmbh Nuevo proceso para la preparacion de reflumilast.
JP2007536350A (ja) * 2004-05-10 2007-12-13 ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング 肺気腫の予防又は治療のためのロフルミラストの使用
CA2589808A1 (en) * 2004-11-02 2006-05-11 Dainippon Sumitomo Pharma Co., Ltd. Combination drug for treating autoimmune disease
EP2363128B1 (en) * 2005-03-11 2016-02-17 Vertex Pharmaceuticals Incorporated Indole modulators of ATP-binding cassette transporters
US8663694B2 (en) * 2005-03-16 2014-03-04 Takeda Gmbh Taste masked dosage form containing roflumilast
KR100838702B1 (ko) * 2007-02-08 2008-06-16 한국화학연구원 1-[1-(3,4-디알콕시아릴)-피리딜메틸]-1ｈ-피라졸 화합물의제조방법
WO2010091381A2 (en) * 2009-02-09 2010-08-12 Callisto Pharmaceuticals, Inc. An intermittent dosing strategy for treating rheumatoid arthrtis
WO2013016718A1 (en) * 2011-07-28 2013-01-31 Cellworks Research India Private Limited Compositions, process of preparation of said compositions and method of treating inflammatory diseases
BR112015019276A2 (pt) 2013-02-19 2017-07-18 Pfizer compostos de azabenzimidazol como inibidores de isoenzimas de pde4 para o tratamento de distúrbios do snc e outros distúrbios
WO2016012896A1 (en) 2014-07-24 2016-01-28 Pfizer Inc. Pyrazolopyrimidine compounds
MD20170011A2 (ro) 2014-08-06 2017-08-31 Pfizer Inc. Compuşi imidazopiridazinici
US11977085B1 (en) 2023-09-05 2024-05-07 Elan Ehrlich Date rape drug detection device and method of using same

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000053182A2 (en) * 1999-03-10 2000-09-14 Byk Gulden Lomberg Chemische Fabrik Gmbh 3-cyclopropylmethoxy-4-difluoromethoxy-n-(3,5-dichloropyrid-4-yl)benzamide in the treatment of multiple sclerosis

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