JP2005508146A5 - - Google Patents
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- Publication number
- JP2005508146A5 JP2005508146A5 JP2003506308A JP2003506308A JP2005508146A5 JP 2005508146 A5 JP2005508146 A5 JP 2005508146A5 JP 2003506308 A JP2003506308 A JP 2003506308A JP 2003506308 A JP2003506308 A JP 2003506308A JP 2005508146 A5 JP2005508146 A5 JP 2005508146A5
- Authority
- JP
- Japan
- Prior art keywords
- polypeptide
- seq
- amino acid
- acid sequence
- antibody
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 229920001184 polypeptide Polymers 0.000 claims description 154
- 102000004196 processed proteins & peptides Human genes 0.000 claims description 154
- 108090000765 processed proteins & peptides Proteins 0.000 claims description 154
- 239000012634 fragment Substances 0.000 claims description 40
- 108091033319 polynucleotide Proteins 0.000 claims description 40
- 239000002157 polynucleotide Substances 0.000 claims description 40
- 102000040430 polynucleotide Human genes 0.000 claims description 40
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims description 36
- 125000003275 alpha amino acid group Chemical group 0.000 claims description 32
- 239000000203 mixture Substances 0.000 claims description 12
- 241000588621 Moraxella Species 0.000 claims description 10
- 239000000427 antigen Substances 0.000 claims description 9
- 102000036639 antigens Human genes 0.000 claims description 9
- 108091007433 antigens Proteins 0.000 claims description 9
- 238000000034 method Methods 0.000 claims description 9
- 239000012472 biological sample Substances 0.000 claims description 8
- 206010062204 Moraxella infection Diseases 0.000 claims description 7
- 208000031548 Moraxellaceae Infections Diseases 0.000 claims description 7
- 239000008194 pharmaceutical composition Substances 0.000 claims description 6
- 238000004519 manufacturing process Methods 0.000 claims description 4
- 125000001360 methionine group Chemical group N[C@@H](CCSC)C(=O)* 0.000 claims description 4
- 206010010741 Conjunctivitis Diseases 0.000 claims description 3
- 206010011224 Cough Diseases 0.000 claims description 3
- 201000008197 Laryngitis Diseases 0.000 claims description 3
- 206010033078 Otitis media Diseases 0.000 claims description 3
- 201000010550 acute laryngitis Diseases 0.000 claims description 3
- 239000003814 drug Substances 0.000 claims description 3
- 206010023332 keratitis Diseases 0.000 claims description 3
- 201000009890 sinusitis Diseases 0.000 claims description 3
- 239000002671 adjuvant Substances 0.000 claims description 2
- 238000012258 culturing Methods 0.000 claims description 2
- 239000003085 diluting agent Substances 0.000 claims description 2
- 239000003937 drug carrier Substances 0.000 claims description 2
- 230000002163 immunogen Effects 0.000 claims 14
- 239000002773 nucleotide Substances 0.000 claims 14
- 125000003729 nucleotide group Chemical group 0.000 claims 14
- 150000001413 amino acids Chemical class 0.000 claims 8
- 230000001939 inductive effect Effects 0.000 claims 8
- 241000588655 Moraxella catarrhalis Species 0.000 claims 4
- 230000028993 immune response Effects 0.000 claims 4
- 208000015181 infectious disease Diseases 0.000 claims 4
- 230000000069 prophylactic effect Effects 0.000 claims 3
- 230000005847 immunogenicity Effects 0.000 claims 2
- 230000003248 secreting effect Effects 0.000 claims 2
- 230000001225 therapeutic effect Effects 0.000 claims 2
- 238000001514 detection method Methods 0.000 claims 1
- 238000003745 diagnosis Methods 0.000 claims 1
- 230000002458 infectious effect Effects 0.000 claims 1
- 238000000926 separation method Methods 0.000 claims 1
- 108091028043 Nucleic acid sequence Proteins 0.000 description 8
- 230000000295 complement effect Effects 0.000 description 6
- 230000002265 prevention Effects 0.000 description 5
- 125000000539 amino acid group Chemical group 0.000 description 2
- 108020004414 DNA Proteins 0.000 description 1
- 208000013116 chronic cough Diseases 0.000 description 1
- 238000002405 diagnostic procedure Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US29840301P | 2001-06-18 | 2001-06-18 | |
| US33009501P | 2001-10-19 | 2001-10-19 | |
| PCT/CA2002/000911 WO2002102836A2 (en) | 2001-06-18 | 2002-06-18 | Moraxella (branhamella) catarrhalis antigens |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005508146A JP2005508146A (ja) | 2005-03-31 |
| JP2005508146A5 true JP2005508146A5 (enExample) | 2009-12-03 |
Family
ID=26970641
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003506308A Ceased JP2005508146A (ja) | 2001-06-18 | 2002-06-18 | モラクセラ（ブランハメラ）カタラーリス抗原 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20050080233A1 (enExample) |
| EP (2) | EP1399563B1 (enExample) |
| JP (1) | JP2005508146A (enExample) |
| CN (1) | CN1582336A (enExample) |
| AT (1) | ATE421586T1 (enExample) |
| CA (1) | CA2455254A1 (enExample) |
| DE (1) | DE60230984D1 (enExample) |
| WO (1) | WO2002102836A2 (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110540594B (zh) * | 2018-12-20 | 2021-05-11 | 湖北工业大学 | 基于卡他莫拉菌表面蛋白的乳胶微球免疫层析试纸的制备方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4425437A (en) | 1979-11-05 | 1984-01-10 | Genentech, Inc. | Microbial polypeptide expression vehicle |
| US4431739A (en) | 1979-11-05 | 1984-02-14 | Genentech, Inc. | Transformant bacterial culture capable of expressing heterologous protein |
| US4338397A (en) | 1980-04-11 | 1982-07-06 | President And Fellows Of Harvard College | Mature protein synthesis |
| GB9817824D0 (en) * | 1998-08-14 | 1998-10-14 | Smithkline Beecham Biolog | Novel compounds |
| AU1824101A (en) * | 1999-06-18 | 2001-01-09 | Elitra Pharmaceuticals, Inc. | Nucleotide sequences of moraxella catarrhalis genome |
-
2002
- 2002-06-18 EP EP02742581A patent/EP1399563B1/en not_active Expired - Lifetime
- 2002-06-18 CA CA002455254A patent/CA2455254A1/en not_active Abandoned
- 2002-06-18 AT AT02742581T patent/ATE421586T1/de not_active IP Right Cessation
- 2002-06-18 EP EP09150805A patent/EP2166096A3/en not_active Withdrawn
- 2002-06-18 DE DE60230984T patent/DE60230984D1/de not_active Expired - Fee Related
- 2002-06-18 WO PCT/CA2002/000911 patent/WO2002102836A2/en not_active Ceased
- 2002-06-18 CN CNA02812216XA patent/CN1582336A/zh active Pending
- 2002-06-18 JP JP2003506308A patent/JP2005508146A/ja not_active Ceased
- 2002-06-18 US US10/481,248 patent/US20050080233A1/en not_active Abandoned
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