JP2005507641A5 - - Google Patents
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- JP2005507641A5 JP2005507641A5 JP2002578470A JP2002578470A JP2005507641A5 JP 2005507641 A5 JP2005507641 A5 JP 2005507641A5 JP 2002578470 A JP2002578470 A JP 2002578470A JP 2002578470 A JP2002578470 A JP 2002578470A JP 2005507641 A5 JP2005507641 A5 JP 2005507641A5
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- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US26638601P | 2001-02-02 | 2001-02-02 | |
US60/266,386 | 2001-02-02 | ||
US26878501P | 2001-02-14 | 2001-02-14 | |
US60/268,785 | 2001-02-14 | ||
PCT/US2002/003055 WO2002079468A2 (en) | 2001-02-02 | 2002-02-01 | A method of increasing complementarity in a heteroduplex polynucleotide |
Publications (3)
Publication Number | Publication Date |
---|---|
JP2005507641A JP2005507641A (ja) | 2005-03-24 |
JP2005507641A5 true JP2005507641A5 (ja) | 2005-12-22 |
JP4689940B2 JP4689940B2 (ja) | 2011-06-01 |
Family
ID=26951797
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2002578470A Expired - Fee Related JP4689940B2 (ja) | 2001-02-02 | 2002-02-01 | ヘテロ二本鎖の相補性を増大させる方法 |
Country Status (8)
Country | Link |
---|---|
US (4) | US20020146732A1 (ja) |
EP (1) | EP1358322B1 (ja) |
JP (1) | JP4689940B2 (ja) |
AT (1) | ATE447019T1 (ja) |
AU (1) | AU2002314712C1 (ja) |
CA (1) | CA2436214C (ja) |
DE (1) | DE60234159D1 (ja) |
WO (1) | WO2002079468A2 (ja) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7838219B2 (en) * | 2001-02-02 | 2010-11-23 | Novici Biotech Llc | Method of increasing complementarity in a heteroduplex |
US20110111413A1 (en) * | 2001-02-02 | 2011-05-12 | Padgett Hal S | Method of optimizing codon usage through dna shuffling |
CA2436214C (en) | 2001-02-02 | 2012-12-04 | Large Scale Biology Corporation | A method of increasing complementarity in a heteroduplex polynucleotide |
EP1281757A1 (en) * | 2001-07-31 | 2003-02-05 | Direvo Biotech AG | Method for the production of nucleic acids consisting of stochastically combined parts of source nucleic acids |
US7078211B2 (en) * | 2002-02-01 | 2006-07-18 | Large Scale Biology Corporation | Nucleic acid molecules encoding endonucleases and methods of use thereof |
DE10223057A1 (de) * | 2002-05-24 | 2003-12-11 | Basf Ag | Verfahren zur Erzeugung von Polynukleotidmolekülen |
WO2004016811A2 (en) * | 2002-08-19 | 2004-02-26 | Danmarks Tekniske Universitet (Dtu) | Methods and kit for genes shuffling using tagged primers |
US20040132054A1 (en) * | 2002-08-22 | 2004-07-08 | Direvo Biotech Ag | Method for the selective combinatorial randomization of polynucleotides |
US7429596B2 (en) * | 2003-06-20 | 2008-09-30 | The Regents Of The University Of California | 1H-pyrrolo [2,3-D] pyrimidine derivatives and methods of use thereof |
US20090053261A1 (en) * | 2005-09-08 | 2009-02-26 | Lindbo John A | Modified tobacco mosaic virus particles as scaffolds for display of protein antigens for vaccine applications |
US20060029612A1 (en) * | 2004-04-15 | 2006-02-09 | Large Scale Biology Corporation | Prevention and treatment of recurrent respiratory papillomatosis |
KR20070073917A (ko) * | 2004-10-21 | 2007-07-10 | 뉴 잉글랜드 바이오랩스, 인크 | 개선된 증폭을 위한 핵산 복구 |
EP2069536B1 (en) * | 2006-08-01 | 2014-11-05 | Gen-Probe Incorporated | Methods of nonspecific target capture of nucleic acids |
JP2010514452A (ja) * | 2006-12-29 | 2010-05-06 | アプライド バイオシステムズ インコーポレイテッド | ヘテロ二重鎖による濃縮 |
WO2008094512A2 (en) * | 2007-01-29 | 2008-08-07 | The Ohio Sate University Research Foundation | System for expression of genes in plants from a virus-based expression vector |
CN103945931B (zh) | 2011-09-26 | 2017-03-22 | 基因技术股份公司 | 高效的小体积核酸合成 |
SG10201606285YA (en) | 2012-02-01 | 2016-09-29 | Synthetic Genomics Inc | Materials and methods for the synthesis of error-minimized nucleic acid molecules |
EP2834357B1 (en) | 2012-04-04 | 2017-12-27 | Life Technologies Corporation | Tal-effector assembly platform, customized services, kits and assays |
US10563240B2 (en) | 2013-03-14 | 2020-02-18 | Life Technologies Corporation | High efficiency, small volume nucleic acid synthesis |
GB2526369B (en) | 2014-05-23 | 2019-06-26 | Itt Mfg Enterprises Llc | Electrical connector |
US20160017394A1 (en) | 2014-07-15 | 2016-01-21 | Life Technologies Corporation | Compositions and methods for nucleic acid assembly |
LT3557262T (lt) | 2014-12-09 | 2022-11-10 | Life Technologies Corporation | Didelio efektyvumo nukleorūgščių sintezė mažame tūryje |
WO2017007925A1 (en) | 2015-07-07 | 2017-01-12 | Thermo Fisher Scientific Geneart Gmbh | Enzymatic synthesis of nucleic acid sequences |
EP3359669B1 (en) | 2015-10-06 | 2020-05-13 | Pierce Biotechnology, Inc. | Devices and methods for producing proteins |
US20210147830A1 (en) | 2018-06-29 | 2021-05-20 | Thermo Fisher Scientific Geneart Gmbh | High throughput assembly of nucleic acid molecules |
GB201905303D0 (en) | 2019-04-15 | 2019-05-29 | Thermo Fisher Scient Geneart Gmbh | Multiplex assembly of nucleic acid molecules |
CN115244189A (zh) | 2020-03-06 | 2022-10-25 | 生命科技股份有限公司 | 高序列保真度核酸合成及组装 |
Family Cites Families (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3546806C2 (ja) * | 1985-03-30 | 1991-03-28 | Marc Genf/Geneve Ch Ballivet | |
US4994368A (en) * | 1987-07-23 | 1991-02-19 | Syntex (U.S.A.) Inc. | Amplification method for polynucleotide assays |
US4994366A (en) * | 1988-04-28 | 1991-02-19 | Jac Creative Foods, Inc. | Shrimp analog forming process |
US5556750A (en) * | 1989-05-12 | 1996-09-17 | Duke University | Methods and kits for fractionating a population of DNA molecules based on the presence or absence of a base-pair mismatch utilizing mismatch repair systems |
US5459039A (en) * | 1989-05-12 | 1995-10-17 | Duke University | Methods for mapping genetic mutations |
US5556747A (en) * | 1990-07-09 | 1996-09-17 | E. R. Squibb & Sons, Inc. | Method for site-directed mutagenesis |
DE4112440C1 (ja) | 1991-04-16 | 1992-10-22 | Diagen Institut Fuer Molekularbiologische Diagnostik Gmbh, 4000 Duesseldorf, De | |
US5795747A (en) * | 1991-04-16 | 1998-08-18 | Evotec Biosystems Gmbh | Process for manufacturing new biopolymers |
AU3919293A (en) * | 1992-03-27 | 1993-11-08 | University Of Maryland At Baltimore | Detection of gene mutations with mismatch repair enzymes |
ATE198774T1 (de) * | 1993-11-01 | 2001-02-15 | Amersham Pharm Biotech Inc | Methode zur analyse und manipulation von dna mit hilfe der reparatursystemebei fehelerhaften basenpaarungen |
US6165793A (en) * | 1996-03-25 | 2000-12-26 | Maxygen, Inc. | Methods for generating polynucleotides having desired characteristics by iterative selection and recombination |
WO1996040902A1 (en) * | 1995-06-07 | 1996-12-19 | Trevigen, Inc. | Nucleic acid repair enzyme methods for point mutation detection and in vitro mutagenesis |
US6057103A (en) * | 1995-07-18 | 2000-05-02 | Diversa Corporation | Screening for novel bioactivities |
US6171820B1 (en) * | 1995-12-07 | 2001-01-09 | Diversa Corporation | Saturation mutagenesis in directed evolution |
WO1997021837A1 (en) * | 1995-12-15 | 1997-06-19 | Amersham Life Science, Inc. | Methods for the detection and removal of mutant sequences that arise during enzymatic amplification using mismatch repair systems |
US7115413B2 (en) | 1996-04-01 | 2006-10-03 | Mixis France S.A. | Meiotic recombination in vivo of partially homologous DNA sequences |
CA2256526C (en) | 1996-06-05 | 2007-04-24 | Fox Chase Cancer Center | Mismatch endonucleases and uses thereof in identifying mutations in targeted polynucleotide strands |
US5869245A (en) * | 1996-06-05 | 1999-02-09 | Fox Chase Cancer Center | Mismatch endonuclease and its use in identifying mutations in targeted polynucleotide strands |
FR2772048B1 (fr) | 1997-12-04 | 2001-12-21 | Biomethodes | Procede de clonage par digestion multiple, vecteurs pour sa mise en oeuvre et ses applications |
EP2270234B1 (en) * | 1997-12-08 | 2013-03-06 | California Institute of Technology | Method for creating polynucleotide and polypeptide sequences |
MXPA00007891A (es) * | 1998-02-11 | 2002-09-18 | Maxygen Inc | Diseno de vector de vacuna genetica. |
US6846655B1 (en) * | 1998-06-29 | 2005-01-25 | Phylos, Inc. | Methods for generating highly diverse libraries |
AU761570B2 (en) * | 1998-06-29 | 2003-06-05 | Bristol-Myers Squibb Company | Methods for generating highly diverse libraries |
US6376246B1 (en) * | 1999-02-05 | 2002-04-23 | Maxygen, Inc. | Oligonucleotide mediated nucleic acid recombination |
FR2789696A1 (fr) | 1999-02-12 | 2000-08-18 | Biomethodes | Procede de mutagenese d'un fragment d'acide nucleique par clonage et polymerisation-ligation |
FR2793807B1 (fr) | 1999-05-20 | 2003-05-16 | Biomethodes | Methode d'insertion d'un fragment d'acide nucleique dans un vecteur, ses applications et les kits pour sa mise en oeuvre |
DE19953854C2 (de) | 1999-11-09 | 2002-01-17 | Max Planck Gesellschaft | Verfahren zur Herstellung von Biopolymeren mit veränderten Eigenschaften |
EP1257671B1 (en) | 2000-02-22 | 2015-01-14 | Fox Chase Cancer Center | Nucleic acid molecule encoding a mismatch endonuclease and methods of use thereof |
US6391557B1 (en) * | 2000-02-22 | 2002-05-21 | Fox Chase Cancer Center | Nucleic acid molecule encoding a mismatch endonuclease and methods of use thereof |
CA2405520A1 (en) * | 2000-05-23 | 2001-11-29 | California Institute Of Technology | Gene recombination and hybrid protein development |
FR2813314B1 (fr) | 2000-08-25 | 2004-05-07 | Biomethodes | Procede de mutagenese dirigee massive |
EP1335989A4 (en) * | 2000-09-21 | 2005-01-26 | Merck & Co Inc | METHOD FOR GENERATING RECOMBINANT POLYNUCLEOTIDES |
US6783941B2 (en) * | 2000-12-06 | 2004-08-31 | Novozymes A/S | Method for producing a polynucleotide library in vitro by mismatch repair of heteroduplexes |
CA2436214C (en) * | 2001-02-02 | 2012-12-04 | Large Scale Biology Corporation | A method of increasing complementarity in a heteroduplex polynucleotide |
US7078211B2 (en) * | 2002-02-01 | 2006-07-18 | Large Scale Biology Corporation | Nucleic acid molecules encoding endonucleases and methods of use thereof |
DE10248258A1 (de) | 2002-10-16 | 2004-05-06 | Biopsytec Analytik Gmbh | Mutierte Nukleinsäure einer Cel I-Endonuklease und Verfahren zur Herstellung des rekombinanten vollständigen Cel I-Proteins |
-
2002
- 2002-02-01 CA CA2436214A patent/CA2436214C/en not_active Expired - Fee Related
- 2002-02-01 US US10/066,390 patent/US20020146732A1/en not_active Abandoned
- 2002-02-01 EP EP02741635A patent/EP1358322B1/en not_active Expired - Lifetime
- 2002-02-01 AT AT02741635T patent/ATE447019T1/de not_active IP Right Cessation
- 2002-02-01 DE DE60234159T patent/DE60234159D1/de not_active Expired - Lifetime
- 2002-02-01 AU AU2002314712A patent/AU2002314712C1/en not_active Ceased
- 2002-02-01 WO PCT/US2002/003055 patent/WO2002079468A2/en active Application Filing
- 2002-02-01 JP JP2002578470A patent/JP4689940B2/ja not_active Expired - Fee Related
- 2002-07-25 US US10/205,772 patent/US7235386B2/en not_active Expired - Fee Related
- 2002-07-25 US US10/206,030 patent/US7217514B2/en not_active Expired - Lifetime
-
2007
- 2007-06-25 US US11/768,157 patent/US7833759B2/en not_active Expired - Fee Related