JP2005507635A5 - - Google Patents

Download PDF

Info

Publication number
JP2005507635A5
JP2005507635A5 JP2002564963A JP2002564963A JP2005507635A5 JP 2005507635 A5 JP2005507635 A5 JP 2005507635A5 JP 2002564963 A JP2002564963 A JP 2002564963A JP 2002564963 A JP2002564963 A JP 2002564963A JP 2005507635 A5 JP2005507635 A5 JP 2005507635A5
Authority
JP
Japan
Prior art keywords
antibody
human
antigen
seq
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2002564963A
Other languages
English (en)
Japanese (ja)
Other versions
JP2005507635A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2002/004024 external-priority patent/WO2002064634A2/en
Publication of JP2005507635A publication Critical patent/JP2005507635A/ja
Publication of JP2005507635A5 publication Critical patent/JP2005507635A5/ja
Pending legal-status Critical Current

Links

JP2002564963A 2001-02-12 2002-02-11 Fcα受容体(CD89)に対するヒトモノクローナル抗体 Pending JP2005507635A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US26807501P 2001-02-12 2001-02-12
US33895601P 2001-11-05 2001-11-05
PCT/US2002/004024 WO2002064634A2 (en) 2001-02-12 2002-02-11 Human monoclonal antibodies to fc alpha receptor (cd89)

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2009187733A Division JP2010004888A (ja) 2001-02-12 2009-08-13 Fcα受容体(CD89)に対するヒトモノクローナル抗体

Publications (2)

Publication Number Publication Date
JP2005507635A JP2005507635A (ja) 2005-03-24
JP2005507635A5 true JP2005507635A5 (https=) 2005-12-22

Family

ID=26952868

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2002564963A Pending JP2005507635A (ja) 2001-02-12 2002-02-11 Fcα受容体(CD89)に対するヒトモノクローナル抗体
JP2009187733A Withdrawn JP2010004888A (ja) 2001-02-12 2009-08-13 Fcα受容体(CD89)に対するヒトモノクローナル抗体

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2009187733A Withdrawn JP2010004888A (ja) 2001-02-12 2009-08-13 Fcα受容体(CD89)に対するヒトモノクローナル抗体

Country Status (12)

Country Link
US (1) US7192582B2 (https=)
EP (1) EP1370588A2 (https=)
JP (2) JP2005507635A (https=)
KR (1) KR100890088B1 (https=)
CN (1) CN1312181C (https=)
AU (1) AU2002240338C1 (https=)
CA (1) CA2437814C (https=)
IL (2) IL157274A0 (https=)
MX (1) MXPA03007144A (https=)
NZ (1) NZ527977A (https=)
WO (1) WO2002064634A2 (https=)
ZA (1) ZA200305996B (https=)

Families Citing this family (62)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7192584B2 (en) * 1991-03-18 2007-03-20 Centocor, Inc. Methods of treating psoriasis with anti-TNF antibodies
US7754208B2 (en) 2001-01-17 2010-07-13 Trubion Pharmaceuticals, Inc. Binding domain-immunoglobulin fusion proteins
JP2005508838A (ja) * 2001-03-23 2005-04-07 アフトン コーポレーション 膵癌の組合せ治療
US20090191232A1 (en) * 2001-05-04 2009-07-30 Gevas Philip C Combination therapy for the treatment of tumors
JP2004536835A (ja) * 2001-07-09 2004-12-09 アフトン コーポレーション 肝臓、肺および食道の癌性ならびに前癌性状態の治療および防止
US20060165675A1 (en) * 2002-08-02 2006-07-27 Richman-Eisenstat Janice Beth Modulation of mesenchymal cells via iga-receptors
JP4689597B2 (ja) * 2003-03-28 2011-05-25 レセプター バイオロジックス インク. ガストリンホルモン免疫アッセイ
AR045563A1 (es) 2003-09-10 2005-11-02 Warner Lambert Co Anticuerpos dirigidos a m-csf
EP1570858A1 (en) * 2004-03-05 2005-09-07 Institut National De La Sante Et De La Recherche Medicale (Inserm) Monovalent ligand of the FCalphaRi receptor as an anti-inflammatory agent
EP1730193A2 (en) * 2004-03-29 2006-12-13 Receptor Biologix, Inc. Monoclonal antibodies to gastrin hormone
KR101333168B1 (ko) 2004-09-22 2013-11-28 리셉터 바이오로직스 인크 프로가스트린에 대한 모노클로날 항체
CA2606081C (en) 2005-04-26 2013-09-17 Markus M. Heiss Combination of the application of antibodies for immunostimulation together with glucocorticoids
HRP20140338T1 (hr) 2005-07-25 2014-06-20 Emergent Product Development Seattle, Llc Smanjenje broja b-stanica upotrebom molekula koje se specifiäśno vežu na cd37 i cd20
WO2007146968A2 (en) 2006-06-12 2007-12-21 Trubion Pharmaceuticals, Inc. Single-chain multivalent binding proteins with effector function
KR101491700B1 (ko) 2007-08-23 2015-02-11 가부시키가이샤 엘에스아이 메디엔스 비특이반응 억제제
EP2365003A1 (en) 2008-04-11 2011-09-14 Emergent Product Development Seattle, LLC CD37 immunotherapeutic and combination with bifunctional chemotherapeutic thereof
EP2127666A1 (en) * 2008-05-28 2009-12-02 Drug Discovery Factory B.V. Method for the treatment or prophylaxis of chronic inflammatory diseases
WO2011088219A2 (en) * 2010-01-13 2011-07-21 The Uab Research Foundation Therapeutics and processes for treatment of immune disorders
EP3165540A1 (en) 2010-04-13 2017-05-10 Celldex Therapeutics, Inc. Antibodies that bind human cd27 and uses thereof
WO2012021512A2 (en) 2010-08-10 2012-02-16 Ecole Polytechnique Federale De Lausanne Erythrocyte-binding therapeutics
US9517257B2 (en) 2010-08-10 2016-12-13 Ecole Polytechnique Federale De Lausanne (Epfl) Erythrocyte-binding therapeutics
US9850296B2 (en) 2010-08-10 2017-12-26 Ecole Polytechnique Federale De Lausanne (Epfl) Erythrocyte-binding therapeutics
TW201302793A (zh) 2010-09-03 2013-01-16 Glaxo Group Ltd 新穎之抗原結合蛋白
EP2465536A1 (en) * 2010-12-14 2012-06-20 CSL Behring AG CD89 activation in therapy
EP3575794A1 (en) * 2012-02-10 2019-12-04 Seattle Genetics, Inc. Detection and treatment of cd30+ cancers
EP2636684A1 (en) 2012-03-09 2013-09-11 CSL Behring AG Prevention of infection
EP2636681A1 (en) 2012-03-09 2013-09-11 CSL Behring AG Process for enriching IgA
ES2751976T3 (es) 2012-03-09 2020-04-02 Csl Behring Ag Composiciones que comprenden inmunoglobulinas de tipo secretor
KR102717969B1 (ko) 2014-02-21 2024-10-15 에꼴 뽈리떼끄닉 뻬데랄 드 로잔느 (으뻬에프엘) 글리코타겟팅 치료제
US10946079B2 (en) 2014-02-21 2021-03-16 Ecole Polytechnique Federale De Lausanne Glycotargeting therapeutics
US10046056B2 (en) 2014-02-21 2018-08-14 École Polytechnique Fédérale De Lausanne (Epfl) Glycotargeting therapeutics
US10953101B2 (en) 2014-02-21 2021-03-23 École Polytechnique Fédérale De Lausanne (Epfl) Glycotargeting therapeutics
CA2980642C (en) * 2015-03-25 2022-09-20 Fraunhofer-Gesellschaft Zur Forderung Der Angewandten Forschung E.V. Anti-cd89 cytotoxic complex
UY36751A (es) 2015-06-26 2017-01-31 Novartis Ag Anticuerpos de factor xi y métodos de uso
EP3352760B1 (en) 2015-09-21 2026-03-11 Aptevo Research and Development LLC Cd3 binding polypeptides
TW201802121A (zh) 2016-05-25 2018-01-16 諾華公司 抗因子XI/XIa抗體之逆轉結合劑及其用途
EP3904880A1 (fr) * 2016-09-30 2021-11-03 Centre national de la recherche scientifique Marqueurs membranaires
US12188935B2 (en) 2016-09-30 2025-01-07 Centre National De La Recherche Scientifique Method for the evaluation of antiretroviral therapy (ART) effectiveness in HIV-1 CD4+CD89+ cellular reservoirs
US10610104B2 (en) 2016-12-07 2020-04-07 Progenity, Inc. Gastrointestinal tract detection methods, devices and systems
IL267538B2 (en) 2016-12-23 2024-05-01 Novartis Ag Antibodies against factor XI and methods for use in preventing, treating, managing or reducing the risk of thromboembolic disorder or stroke in a patient
US20210138213A1 (en) 2017-03-30 2021-05-13 Progenity, Inc. Treatment of a disease of the gastrointestinal tract with an immune modulatory agent released using an ingestible device
WO2018232230A1 (en) 2017-06-15 2018-12-20 Cancer Advances Inc. Compositions and methods for inducing humoral and cellular immunities against tumors and cancer
US12150978B2 (en) 2017-06-15 2024-11-26 Cancer Advances Inc. Compositions and methods for preventing tumors and cancer
US11253579B2 (en) 2017-06-16 2022-02-22 The University Of Chicago Compositions and methods for inducing immune tolerance
JP7009517B2 (ja) 2017-06-21 2022-01-25 ギリアード サイエンシーズ, インコーポレイテッド Hiv gp120およびcd3を標的とする多重特異性抗体
US11459393B2 (en) 2018-04-17 2022-10-04 Celldex Therapeutics, Inc. Anti-CD27 and anti-PD-L1 antibodies and bispecific constructs
EA202092723A1 (ru) 2018-05-09 2021-04-09 Зе Юниверсити Оф Чикаго Композиции и способы, касающиеся иммунной толерантности
WO2019246312A1 (en) 2018-06-20 2019-12-26 Progenity, Inc. Treatment of a disease of the gastrointestinal tract with an immunomodulator
US12227565B2 (en) 2018-06-20 2025-02-18 Biora Therapeutics, Inc. Method of formulating a pharmaceutical composition comprising administering an immune modulator to the small intestine
US20220249814A1 (en) 2018-11-19 2022-08-11 Progenity, Inc. Methods and devices for treating a disease with biotherapeutics
CN121197633A (zh) 2019-12-13 2025-12-26 比特比德科有限责任公司 用于将治疗剂递送至胃肠道的可摄取装置
JP7754841B2 (ja) * 2020-04-21 2025-10-15 ジェイジェイピー バイオロジクス エスピー.ゼット オー.オー. ヒト化抗ヒトcd89抗体及びその使用
JP2023545099A (ja) 2020-10-08 2023-10-26 アフィメド ゲーエムベーハー 三重特異性バインダー
KR102766045B1 (ko) * 2020-11-06 2025-02-10 고려대학교 산학협력단 Fc 알파 수용체 결합력이 향상된 항체
KR102855679B1 (ko) * 2020-11-06 2025-09-04 고려대학교 산학협력단 Fc 알파 수용체 결합 항체
CN116419928A (zh) * 2020-11-06 2023-07-11 高丽大学校产学协力团 Fcα受体结合抗体
KR102853685B1 (ko) * 2020-11-06 2025-09-01 고려대학교 산학협력단 Fc 알파 수용체 결합력이 증진된 항체
CA3216098A1 (en) 2021-07-30 2023-02-02 Uwe Reusch Duplexbodies
WO2024218512A1 (en) 2023-04-19 2024-10-24 Centessa Pharmaceuticals (Uk) Limited Activatable bispecific anti-cd89 and anti-pd-l1 proteins and uses thereof
CN117890576A (zh) * 2023-12-12 2024-04-16 深圳市陆为生物技术有限公司 一种检测CD89-IgA免疫复合物的试剂、方法及其应用
WO2025218725A1 (zh) * 2024-04-18 2025-10-23 徕特康(苏州)生物制药有限公司 靶向cd20和cd89的髓细胞衔接子抗体及其用途
WO2026002175A1 (zh) * 2024-06-27 2026-01-02 无锡徕特康生物科技有限公司 靶向ilt7和cd89的髓细胞衔接子抗体及其用途

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05504677A (ja) 1989-10-20 1993-07-22 トラスティーズ オブ ダートマス カレッジ IgAレセプターに特異的なモノクロナール抗体
US6018031A (en) * 1989-10-20 2000-01-25 Trustees Of Dartmouth College Binding agents specific for IgA receptor
US5859205A (en) * 1989-12-21 1999-01-12 Celltech Limited Humanised antibodies
US5198342A (en) * 1990-07-05 1993-03-30 Immunex Corporation DNA encoding IgA Fc receptors
US6300129B1 (en) 1990-08-29 2001-10-09 Genpharm International Transgenic non-human animals for producing heterologous antibodies
ATE300615T1 (de) 1990-08-29 2005-08-15 Genpharm Int Transgene mäuse fähig zur produktion heterologer antikörper
CA2161351C (en) 1993-04-26 2010-12-21 Nils Lonberg Transgenic non-human animals capable of producing heterologous antibodies
US5922845A (en) * 1996-07-11 1999-07-13 Medarex, Inc. Therapeutic multispecific compounds comprised of anti-Fcα receptor antibodies
DE60036388D1 (de) * 1999-07-30 2007-10-25 Medarex Inc Therapeutische verbindungen bestehend aus fc rezeptor bindenden wirkstoffen
ATE553131T1 (de) 2000-05-08 2012-04-15 Celldex Res Corp Humane monoklonale antikörper gegen dendritische zellen

Similar Documents

Publication Publication Date Title
JP2005507635A5 (https=)
US12324842B2 (en) Compositions and methods for making antibody conjugates
US20230295340A1 (en) Muc1* antibodies
IL157274A (en) 89CD monoclonal antibodies of human origin, their segments that bind to antigens, hybridomas and transpectomas that produce them, transgenic cells that express them, couplings of biospecific and multispecific molecules, immunotoxins and preparations containing them, methods for their production and methods for detection
JP7461950B2 (ja) Cd3抗体およびその医薬用途
JP6273219B2 (ja) 天然の免疫グロブリン形式を有する容易に単離される二重特異性抗体
EP3353213B1 (en) Anti-mesothelin antibody and composition comprising the same
JP2003516718A5 (https=)
CA2892059C (en) Bispecific antibody
CN112851808B (zh) Igf-1r抗体及其作为定位载体用于治疗癌症的用途
TWI854953B (zh) 抗cd3抗體及含有該抗體的分子、及其製造方法
RU2013142600A (ru) Белки, связывающие специфический мембранный антиген простаты, и соответствующие композиции и способы
CN112969476B (zh) 多特异性蛋白分子
JP2018509907A5 (https=)
SI2511301T1 (en) Human antibodies to ERBB 2
JP2009297037A5 (https=)
US20230080842A1 (en) Tetravalent symmetric bispecific antibodies
RU2017134592A (ru) Антитела к muc16 и их применение
CN102459346A (zh) 制造异源多聚体分子的方法
JP2008520186A (ja) 哺乳類eag1イオンチャネルタンパク質に対する新規の抗体
ME02842B (me) Potpuno ljudska antitijela specifična za cadm1
WO2021097800A1 (en) Anti-pd-l1/anti-b7-h3 multispecific antibodies and uses thereof
WO2024175093A1 (en) Antibodies, antigen-binding fragments and methods of use
WO2022166876A1 (zh) 特异性识别磷脂酰肌醇蛋白聚糖3的单克隆抗体及其应用
US20220354962A1 (en) Rapid production of bispecific antibodies from off-the-shelf iggs with high yield and purity