JP2005507635A - Fcα受容体(CD89)に対するヒトモノクローナル抗体 - Google Patents

Fcα受容体(CD89)に対するヒトモノクローナル抗体 Download PDF

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JP2005507635A
JP2005507635A JP2002564963A JP2002564963A JP2005507635A JP 2005507635 A JP2005507635 A JP 2005507635A JP 2002564963 A JP2002564963 A JP 2002564963A JP 2002564963 A JP2002564963 A JP 2002564963A JP 2005507635 A JP2005507635 A JP 2005507635A
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antibody
human
antigen
cells
binding
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JP2005507635A5 (enExample
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デブラ ハドソン,
デ ウィンケン, ヤン ファン
ダイク, マルクス, エー. ファン
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ER Squibb and Sons LLC
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Medarex LLC
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    • C07ORGANIC CHEMISTRY
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    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/283Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against Fc-receptors, e.g. CD16, CD32, CD64
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    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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    • A61K47/68Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6835Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
    • A61K47/6875Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody being a hybrid immunoglobulin
    • A61K47/6879Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody being a hybrid immunoglobulin the immunoglobulin having two or more different antigen-binding sites, e.g. bispecific or multispecific immunoglobulin
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    • C07K2317/00Immunoglobulins specific features
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    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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    • C07K2319/00Fusion polypeptide
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    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70503Immunoglobulin superfamily, e.g. VCAMs, PECAM, LFA-3
    • G01N2333/70535Fc-receptors, e.g. CD16, CD32, CD64 (CD2314/705F)

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JP2002564963A 2001-02-12 2002-02-11 Fcα受容体(CD89)に対するヒトモノクローナル抗体 Pending JP2005507635A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US26807501P 2001-02-12 2001-02-12
US33895601P 2001-11-05 2001-11-05
PCT/US2002/004024 WO2002064634A2 (en) 2001-02-12 2002-02-11 Human monoclonal antibodies to fc alpha receptor (cd89)

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JP2009187733A Division JP2010004888A (ja) 2001-02-12 2009-08-13 Fcα受容体(CD89)に対するヒトモノクローナル抗体

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JP2005507635A true JP2005507635A (ja) 2005-03-24
JP2005507635A5 JP2005507635A5 (enExample) 2005-12-22

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JP2002564963A Pending JP2005507635A (ja) 2001-02-12 2002-02-11 Fcα受容体(CD89)に対するヒトモノクローナル抗体
JP2009187733A Withdrawn JP2010004888A (ja) 2001-02-12 2009-08-13 Fcα受容体(CD89)に対するヒトモノクローナル抗体

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US (1) US7192582B2 (enExample)
EP (1) EP1370588A2 (enExample)
JP (2) JP2005507635A (enExample)
KR (1) KR100890088B1 (enExample)
CN (1) CN1312181C (enExample)
AU (1) AU2002240338C1 (enExample)
CA (1) CA2437814C (enExample)
IL (2) IL157274A0 (enExample)
MX (1) MXPA03007144A (enExample)
NZ (1) NZ527977A (enExample)
WO (1) WO2002064634A2 (enExample)
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US7592430B2 (en) 2003-09-10 2009-09-22 Amgen Fremont Antibodies to M-CSF
JP2013531970A (ja) * 2010-04-13 2013-08-15 セルデックス・セラピューティクス・インコーポレイテッド ヒトcd27に結合する抗体およびその使用
JP2019530872A (ja) * 2016-09-30 2019-10-24 セントレ ナショナル デ ラ レセルシュ シャンティフィク 膜マーカー
US11332537B2 (en) 2018-04-17 2022-05-17 Celldex Therapeutics, Inc. Anti-CD27 and anti-PD-L1 antibodies and bispecific constructs
JP2023523919A (ja) * 2020-04-21 2023-06-08 ジェイジェイピー バイオロジクス エスピー.ゼット オー.オー. ヒト化抗ヒトcd89抗体及びその使用
US12188935B2 (en) 2016-09-30 2025-01-07 Centre National De La Recherche Scientifique Method for the evaluation of antiretroviral therapy (ART) effectiveness in HIV-1 CD4+CD89+ cellular reservoirs

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US7754208B2 (en) 2001-01-17 2010-07-13 Trubion Pharmaceuticals, Inc. Binding domain-immunoglobulin fusion proteins
JP2005508838A (ja) * 2001-03-23 2005-04-07 アフトン コーポレーション 膵癌の組合せ治療
US20090191232A1 (en) * 2001-05-04 2009-07-30 Gevas Philip C Combination therapy for the treatment of tumors
AU2002326356A1 (en) * 2001-07-09 2003-01-29 Aphton Corporation Treatment and prevention of cancerous and pre-cancerous conditions of the liver, lung and esophagus
US20060165675A1 (en) * 2002-08-02 2006-07-27 Richman-Eisenstat Janice Beth Modulation of mesenchymal cells via iga-receptors
WO2004088326A2 (en) * 2003-03-28 2004-10-14 Aphton Corporation Gastrin hormone immunoassays
US20060020119A1 (en) * 2004-03-29 2006-01-26 Stephen Grimes Monoclonal antibodies to gastrin hormone
EP1570858A1 (en) * 2004-03-05 2005-09-07 Institut National De La Sante Et De La Recherche Medicale (Inserm) Monovalent ligand of the FCalphaRi receptor as an anti-inflammatory agent
EP1794586B1 (en) 2004-09-22 2013-01-30 Cancer Advances, Inc., Monoclonal antibodies to progastrin
ES2417065T3 (es) 2005-04-26 2013-08-05 Trion Pharma Gmbh Combinación de anticuerpos con glucocorticoides para el tratamiento del cáncer
EP2295080A3 (en) 2005-07-25 2011-06-22 Emergent Product Development Seattle, LLC B-cell reduction using CD37-specific and CD20-specific binding molecules
CN105837690A (zh) 2006-06-12 2016-08-10 新兴产品开发西雅图有限公司 具有效应功能的单链多价结合蛋白
AU2008289857B2 (en) 2007-08-23 2014-06-05 Phc Corporation Use of non-specific reaction inhibitor
PT2132228E (pt) 2008-04-11 2011-10-11 Emergent Product Dev Seattle Imunoterapia de cd37 e sua combinação com um quimioterápico bifuncional
EP2127666A1 (en) * 2008-05-28 2009-12-02 Drug Discovery Factory B.V. Method for the treatment or prophylaxis of chronic inflammatory diseases
WO2011088219A2 (en) * 2010-01-13 2011-07-21 The Uab Research Foundation Therapeutics and processes for treatment of immune disorders
US9850296B2 (en) 2010-08-10 2017-12-26 Ecole Polytechnique Federale De Lausanne (Epfl) Erythrocyte-binding therapeutics
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