JP2005506307A5 - - Google Patents
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- Publication number
- JP2005506307A5 JP2005506307A5 JP2002586990A JP2002586990A JP2005506307A5 JP 2005506307 A5 JP2005506307 A5 JP 2005506307A5 JP 2002586990 A JP2002586990 A JP 2002586990A JP 2002586990 A JP2002586990 A JP 2002586990A JP 2005506307 A5 JP2005506307 A5 JP 2005506307A5
- Authority
- JP
- Japan
- Prior art keywords
- receptor binding
- group
- hydrogen
- binding molecules
- conr
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 229910052739 hydrogen Inorganic materials 0.000 claims 50
- 239000001257 hydrogen Substances 0.000 claims 50
- 150000002431 hydrogen Chemical class 0.000 claims 36
- 102000005962 receptors Human genes 0.000 claims 30
- 108020003175 receptors Proteins 0.000 claims 30
- 125000000008 (C1-C10) alkyl group Chemical group 0.000 claims 22
- 150000001875 compounds Chemical class 0.000 claims 19
- 125000000172 C5-C10 aryl group Chemical group 0.000 claims 16
- 235000014633 carbohydrates Nutrition 0.000 claims 16
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 16
- 125000005647 linker group Chemical group 0.000 claims 16
- 108010073466 Bombesin Receptors Proteins 0.000 claims 14
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 14
- 108060003370 Neurotensin receptor Proteins 0.000 claims 14
- 102000017922 Neurotensin receptor Human genes 0.000 claims 14
- 108050001286 Somatostatin Receptor Proteins 0.000 claims 14
- 102000011096 Somatostatin receptor Human genes 0.000 claims 14
- 108010085012 Steroid Receptors Proteins 0.000 claims 14
- 125000000217 alkyl group Chemical group 0.000 claims 14
- 102000005969 steroid hormone receptors Human genes 0.000 claims 14
- 108090001085 Cholecystokinin Receptors Proteins 0.000 claims 10
- 102000004859 Cholecystokinin Receptors Human genes 0.000 claims 10
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 8
- 125000003118 aryl group Chemical group 0.000 claims 6
- 239000011203 carbon fibre reinforced carbon Substances 0.000 claims 6
- 101800001982 Cholecystokinin Proteins 0.000 claims 4
- 102100025841 Cholecystokinin Human genes 0.000 claims 4
- 125000004183 alkoxy alkyl group Chemical group 0.000 claims 4
- 229910052799 carbon Inorganic materials 0.000 claims 4
- 229940107137 cholecystokinin Drugs 0.000 claims 4
- IZTQOLKUZKXIRV-YRVFCXMDSA-N sincalide Chemical compound C([C@@H](C(=O)N[C@@H](CCSC)C(=O)NCC(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC=1C=CC=CC=1)C(N)=O)NC(=O)[C@@H](N)CC(O)=O)C1=CC=C(OS(O)(=O)=O)C=C1 IZTQOLKUZKXIRV-YRVFCXMDSA-N 0.000 claims 4
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims 2
- 125000003545 alkoxy group Chemical group 0.000 claims 2
- 150000001720 carbohydrates Chemical class 0.000 claims 2
- 230000008878 coupling Effects 0.000 claims 2
- 238000010168 coupling process Methods 0.000 claims 2
- 238000005859 coupling reaction Methods 0.000 claims 2
- 229940079593 drug Drugs 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 229940088597 hormone Drugs 0.000 claims 2
- 239000005556 hormone Substances 0.000 claims 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 2
- 102000039446 nucleic acids Human genes 0.000 claims 2
- 108020004707 nucleic acids Proteins 0.000 claims 2
- 150000007523 nucleic acids Chemical class 0.000 claims 2
- 239000000816 peptidomimetic Substances 0.000 claims 2
- 102000004196 processed proteins & peptides Human genes 0.000 claims 2
- 108090000765 processed proteins & peptides Proteins 0.000 claims 2
- 108700028722 receptor-Ck Proteins 0.000 claims 2
- 238000002405 diagnostic procedure Methods 0.000 claims 1
- 238000001126 phototherapy Methods 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/849,163 US6485704B1 (en) | 2001-05-04 | 2001-05-04 | Azo compound for type I pototherapy |
| PCT/US2002/012217 WO2002089858A1 (en) | 2001-05-04 | 2002-04-18 | Azo compounds for type i phototherapy |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005506307A JP2005506307A (ja) | 2005-03-03 |
| JP2005506307A5 true JP2005506307A5 (https=) | 2005-12-22 |
Family
ID=25305212
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002586990A Pending JP2005506307A (ja) | 2001-05-04 | 2002-04-18 | １型光線治療用のアゾ化合物 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US6485704B1 (https=) |
| EP (1) | EP1390080A4 (https=) |
| JP (1) | JP2005506307A (https=) |
| CA (1) | CA2445068C (https=) |
| WO (1) | WO2002089858A1 (https=) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7230088B2 (en) * | 2001-07-03 | 2007-06-12 | Mallinckrodt, Inc. | Compounds for dual photodiagnosis and therapy |
| US6939532B2 (en) * | 2000-01-18 | 2005-09-06 | Mallinckrodt, Inc. | Versatile hydrophilic dyes |
| US7790144B2 (en) * | 2000-01-18 | 2010-09-07 | Mallinckrodt Inc. | Receptor-avid exogenous optical contrast and therapeutic agents |
| US20080233050A1 (en) * | 2000-01-18 | 2008-09-25 | Mallinckrodt Inc. | Diagnostic and therapeutic optical agents |
| US20030017164A1 (en) | 2001-07-03 | 2003-01-23 | Mallinckrodt Inc. | Dye-azide compounds for dual phototherapy |
| US6747151B2 (en) * | 2001-05-04 | 2004-06-08 | Mallinckrodt, Inc. | Azo compounds for type I phototherapy |
| US20030031627A1 (en) * | 2001-07-31 | 2003-02-13 | Mallinckrodt Inc. | Internal image antibodies for optical imaging and therapy |
| US20060239923A1 (en) * | 2003-01-13 | 2006-10-26 | Bracco Imaging S.P.A. | Gastrin releasing peptide compounds |
| US7611692B2 (en) * | 2003-01-13 | 2009-11-03 | Bracco Imaging S.P.A. | Gastrin releasing peptide compounds |
| US8420050B2 (en) | 2003-01-13 | 2013-04-16 | Bracco Imaging S.P.A. | Gastrin releasing peptide compounds |
| US7922998B2 (en) * | 2003-01-13 | 2011-04-12 | Bracco Imaging S.P.A. | Gastrin releasing peptide compounds |
| US7226577B2 (en) * | 2003-01-13 | 2007-06-05 | Bracco Imaging, S. P. A. | Gastrin releasing peptide compounds |
| US7850947B2 (en) | 2003-01-13 | 2010-12-14 | Bracco Imaging S.P.A. | Gastrin releasing peptide compounds |
| US20100022449A1 (en) * | 2006-03-09 | 2010-01-28 | Mallinckrodt Inc. | Receptor-avid exogenous optical contrast and therapeutic agents |
| JP2009531332A (ja) * | 2006-03-23 | 2009-09-03 | ライフ テクノロジーズ コーポレーション | 癌細胞株のインビボイメージングのための方法及び試薬 |
| CA2698639A1 (en) * | 2008-11-24 | 2010-05-24 | Mallinckrodt Inc. | Azo and diaza derivatives and uses thereof in phototherapy |
| US8731655B2 (en) | 2009-05-12 | 2014-05-20 | Mallinckrodt Llc | Compounds containing acyclic N-N bonds for phototherapy |
| US9186349B2 (en) | 2009-05-12 | 2015-11-17 | Mallinckrodt Llc | Diaza heterocyclic compounds for phototherapy |
| US8829020B2 (en) | 2009-07-16 | 2014-09-09 | Mallinckrodt Llc | Compounds and compositions for use in phototherapy and in treatment of ocular neovascular disease and cancers |
| CN118894875A (zh) * | 2024-07-10 | 2024-11-05 | 南京工业大学 | 具有高光热转换效率的近红外二区氟硼甲瓒染料分子及其制备方法、应用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5518888A (en) | 1993-10-26 | 1996-05-21 | Thomas Jefferson University | ST receptor binding compounds and methods of using the same |
| US5605809A (en) | 1994-10-28 | 1997-02-25 | Oncoimmunin, Inc. | Compositions for the detection of proteases in biological samples and methods of use thereof |
| EP1082138B1 (en) * | 1998-06-05 | 2004-08-25 | The Board Of Regents, The University Of Texas System | Texaphyrin conjugates and uses thereof |
| US6190641B1 (en) * | 2000-01-18 | 2001-02-20 | Mallinckrodt Inc. | Indocyanine dyes |
-
2001
- 2001-05-04 US US09/849,163 patent/US6485704B1/en not_active Expired - Fee Related
-
2002
- 2002-04-18 EP EP02769275A patent/EP1390080A4/en not_active Withdrawn
- 2002-04-18 WO PCT/US2002/012217 patent/WO2002089858A1/en not_active Ceased
- 2002-04-18 JP JP2002586990A patent/JP2005506307A/ja active Pending
- 2002-04-18 CA CA2445068A patent/CA2445068C/en not_active Expired - Fee Related
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