JP2005503383A5 - - Google Patents
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- Publication number
- JP2005503383A5 JP2005503383A5 JP2003520752A JP2003520752A JP2005503383A5 JP 2005503383 A5 JP2005503383 A5 JP 2005503383A5 JP 2003520752 A JP2003520752 A JP 2003520752A JP 2003520752 A JP2003520752 A JP 2003520752A JP 2005503383 A5 JP2005503383 A5 JP 2005503383A5
- Authority
- JP
- Japan
- Prior art keywords
- adrenal
- pharmaceutical composition
- hydrocortisone
- disease
- caused
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- JYGXADMDTFJGBT-VWUMJDOOSA-N hydrocortisone Chemical compound O=C1CC[C@]2(C)[C@H]3[C@@H](O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 JYGXADMDTFJGBT-VWUMJDOOSA-N 0.000 claims 20
- 230000001919 adrenal effect Effects 0.000 claims 12
- 229960000890 hydrocortisone Drugs 0.000 claims 10
- 239000008194 pharmaceutical composition Substances 0.000 claims 10
- 230000004064 dysfunction Effects 0.000 claims 8
- 206010010356 Congenital anomaly Diseases 0.000 claims 6
- 208000026872 Addison Disease Diseases 0.000 claims 4
- 206010020880 Hypertrophy Diseases 0.000 claims 4
- 208000025302 chronic primary adrenal insufficiency Diseases 0.000 claims 4
- 208000020576 Adrenal disease Diseases 0.000 claims 2
- 206010001367 Adrenal insufficiency Diseases 0.000 claims 2
- ITRJWOMZKQRYTA-RFZYENFJSA-N Cortisone acetate Chemical compound C1CC2=CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@@](C(=O)COC(=O)C)(O)[C@@]1(C)CC2=O ITRJWOMZKQRYTA-RFZYENFJSA-N 0.000 claims 2
- 206010036049 Polycystic ovaries Diseases 0.000 claims 2
- 208000017515 adrenocortical insufficiency Diseases 0.000 claims 2
- 229960003290 cortisone acetate Drugs 0.000 claims 2
- 230000003111 delayed effect Effects 0.000 claims 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
- 201000010065 polycystic ovary syndrome Diseases 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 230000002459 sustained effect Effects 0.000 claims 1
- 238000013268 sustained release Methods 0.000 claims 1
- 239000012730 sustained-release form Substances 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0119848.0A GB0119848D0 (en) | 2001-08-15 | 2001-08-15 | Delayed and sustained drug release |
| PCT/GB2002/003631 WO2003015793A1 (en) | 2001-08-15 | 2002-08-08 | Delayed and sustained drug release |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005503383A JP2005503383A (ja) | 2005-02-03 |
| JP2005503383A5 true JP2005503383A5 (cg-RX-API-DMAC7.html) | 2006-01-05 |
Family
ID=9920405
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003520752A Pending JP2005503383A (ja) | 2001-08-15 | 2002-08-08 | 遅らせかつ持続された薬剤放出 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20050037074A1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP1416938A1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2005503383A (cg-RX-API-DMAC7.html) |
| CA (1) | CA2493349A1 (cg-RX-API-DMAC7.html) |
| GB (1) | GB0119848D0 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2003015793A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR036741A1 (es) * | 2001-10-05 | 2004-09-29 | Combinatorx Inc | Combinaciones para el tratamiento de los trastornos inmunoinflamatorios |
| TW200517114A (en) * | 2003-10-15 | 2005-06-01 | Combinatorx Inc | Methods and reagents for the treatment of immunoinflammatory disorders |
| GB0400031D0 (en) * | 2004-01-03 | 2004-02-04 | Univ Sheffield | Depression treatment |
| SE0401031D0 (sv) | 2004-04-22 | 2004-04-22 | Duocort Ab | A new glucocorticoid replacement therapy |
| US20080003213A1 (en) * | 2006-05-22 | 2008-01-03 | Jan Lessem | Methods and compositions for the treatment of diseases or conditions associated with increased C-reactive protein, interleukin-6, or interferon-gamma levels |
| GB0623740D0 (en) * | 2006-11-28 | 2007-01-10 | Diurnal Ltd | Treatment of disease |
| CA2737131A1 (en) * | 2007-09-19 | 2009-03-26 | Zalicus Inc. | Therapeutic regimens for the treatment of immunoinflammatory disorders |
| US20110189293A1 (en) * | 2007-12-17 | 2011-08-04 | CombinatoRx, Incoporated | Therapeutic regimens for the treatment of immunoinflammatory disorders |
| GB0817120D0 (en) * | 2008-09-19 | 2008-10-29 | Diurnal Ltd | Treatment of adrenal insufficiency |
| JP2012522816A (ja) * | 2009-04-07 | 2012-09-27 | デュオコート ファーマ エービー | 改良されたグルココルチコイド療法 |
| EP2571505B1 (en) | 2010-05-20 | 2016-07-06 | Shire Viropharma Incorporated | Posology and administration of glucocorticoid based compositions |
| GB201202433D0 (en) | 2012-02-13 | 2012-03-28 | Diurnal Ltd | Controlled drug release |
| JP6754533B2 (ja) | 2015-03-30 | 2020-09-16 | コーセプト セラピューティクス， インコーポレイテッド | 副腎機能不全を処置するための糖質コルチコイドと組み合わせた糖質コルチコイドレセプターアンタゴニストの使用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5792476A (en) * | 1996-12-19 | 1998-08-11 | Abigo Medical Ab | Sustained release glucocorticoid pharmaceutical composition |
| US5788987A (en) * | 1997-01-29 | 1998-08-04 | Poli Industria Chimica Spa | Methods for treating early morning pathologies |
| DE19718012C1 (de) * | 1997-04-29 | 1998-10-08 | Jenapharm Gmbh | Verfahren zur Herstellung peroral anwendbarer fester Arzneiformen mit gesteuerter Wirkstoffabgabe |
| DE10012555A1 (de) * | 2000-03-15 | 2001-09-20 | Merck Patent Gmbh | Glucocorticoide in einer Modified Release-Formulierung |
-
2001
- 2001-08-15 GB GBGB0119848.0A patent/GB0119848D0/en not_active Ceased
-
2002
- 2002-08-08 WO PCT/GB2002/003631 patent/WO2003015793A1/en not_active Ceased
- 2002-08-08 US US10/486,700 patent/US20050037074A1/en not_active Abandoned
- 2002-08-08 CA CA002493349A patent/CA2493349A1/en not_active Abandoned
- 2002-08-08 JP JP2003520752A patent/JP2005503383A/ja active Pending
- 2002-08-08 EP EP02751394A patent/EP1416938A1/en not_active Withdrawn
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