JP2008521783A5 - - Google Patents
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- Publication number
- JP2008521783A5 JP2008521783A5 JP2007542113A JP2007542113A JP2008521783A5 JP 2008521783 A5 JP2008521783 A5 JP 2008521783A5 JP 2007542113 A JP2007542113 A JP 2007542113A JP 2007542113 A JP2007542113 A JP 2007542113A JP 2008521783 A5 JP2008521783 A5 JP 2008521783A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- tnfα
- fragment
- antibody according
- signaling via
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 108060008682 Tumor Necrosis Factor Proteins 0.000 claims 4
- 102000000852 Tumor Necrosis Factor-alpha Human genes 0.000 claims 4
- 239000012634 fragment Substances 0.000 claims 4
- 230000011664 signaling Effects 0.000 claims 4
- 208000023275 Autoimmune disease Diseases 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 208000027866 inflammatory disease Diseases 0.000 claims 2
- 102000008394 Immunoglobulin Fragments Human genes 0.000 claims 1
- 108010021625 Immunoglobulin Fragments Proteins 0.000 claims 1
- 230000001363 autoimmune Effects 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 239000012636 effector Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 238000011321 prophylaxis Methods 0.000 claims 1
- 238000011282 treatment Methods 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0425972.7A GB0425972D0 (en) | 2004-11-25 | 2004-11-25 | Biological products |
| PCT/GB2005/004511 WO2006056779A2 (en) | 2004-11-25 | 2005-11-24 | ANTI-TNF ALPHA ANTIBODIES WHICH SELECTIVELY INHIBIT TNF ALPHA SIGNALLING THROUGH THE p55R |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008521783A JP2008521783A (ja) | 2008-06-26 |
| JP2008521783A5 true JP2008521783A5 (cg-RX-API-DMAC7.html) | 2009-01-08 |
Family
ID=33561379
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007542113A Abandoned JP2008521783A (ja) | 2004-11-25 | 2005-11-24 | ｐ５５Ｒを介するＴＮＦαシグナル伝達を選択的に抑制する抗ＴＮＦα抗体 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US9840556B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP1817344B9 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2008521783A (cg-RX-API-DMAC7.html) |
| ES (1) | ES2553129T3 (cg-RX-API-DMAC7.html) |
| GB (1) | GB0425972D0 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2006056779A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0523954D0 (en) * | 2005-11-24 | 2006-01-04 | Ucb Celltech | Bioassays |
| WO2007060411A1 (en) * | 2005-11-24 | 2007-05-31 | Ucb Pharma S.A. | Anti-tnf alpha antibodies which selectively inhibit tnf alpha signalling through the p55r |
| WO2008045140A1 (en) | 2006-05-19 | 2008-04-17 | Alder Biopharmaceuticals, Inc. | Culture method for obtaining a clonal population of antigen-specific b cells |
| WO2011026128A2 (en) | 2009-08-31 | 2011-03-03 | Life Technologies Corporation | Flowcells and methods of filling and using same |
| WO2011095174A1 (en) | 2010-02-08 | 2011-08-11 | Aarhus Universitet | Human herpes virus 6 and 7 u20 polypeptide and polynucleotides for use as a medicament or diagnosticum |
| GB201522394D0 (en) * | 2015-12-18 | 2016-02-03 | Ucb Biopharma Sprl | Antibodies |
| EP4467565A3 (en) | 2016-12-21 | 2025-03-12 | Amgen Inc. | Anti-tnf alpha antibody formulations |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2055168A1 (en) | 1990-11-21 | 1992-05-22 | Walter Fiers | Tnf-muteins |
| GB9109645D0 (en) * | 1991-05-03 | 1991-06-26 | Celltech Ltd | Recombinant antibodies |
| SK376492A3 (en) | 1992-04-02 | 1995-06-07 | Hoffmann La Roche | Tnf - muteins and method of their production |
| CA2119089A1 (en) | 1993-03-29 | 1994-09-30 | David Banner | Tumor necrosis factor muteins |
| US5606023A (en) | 1994-05-24 | 1997-02-25 | Thomas Jefferson University | Mutant tumor necrosis factor proteins |
| JP2002515459A (ja) | 1998-05-18 | 2002-05-28 | アプライド・リサーチ・システムズ・エイアールエス・ホールディング・ナムローゼ・フェンノートシャップ | 喘息および他のアレルギー性症状を治療するための方法およびｔｎｆ−ｒｉｉ（ｐ７５）アゴニストを含む組成物の使用 |
| DE19957065B4 (de) * | 1999-11-26 | 2005-01-05 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Screening-Verfahren für Arzneistoffe |
| GB0013810D0 (en) * | 2000-06-06 | 2000-07-26 | Celltech Chiroscience Ltd | Biological products |
| UA81743C2 (uk) * | 2000-08-07 | 2008-02-11 | Центокор, Инк. | МОНОКЛОНАЛЬНЕ АНТИТІЛО ЛЮДИНИ, ЩО СПЕЦИФІЧНО ЗВ'ЯЗУЄТЬСЯ З ФАКТОРОМ НЕКРОЗУ ПУХЛИН АЛЬФА (ФНПα), ФАРМАЦЕВТИЧНА КОМПОЗИЦІЯ, ЩО ЙОГО МІСТИТЬ, ТА СПОСІБ ЛІКУВАННЯ РЕВМАТОЇДНОГО АРТРИТУ |
| ATE524196T1 (de) * | 2001-10-16 | 2011-09-15 | Macrogenics West Inc | An das krebsassoziierte antigen cd46 bindende antikörper und verwendungsverfahren dafür |
| AU2003217912A1 (en) * | 2002-03-01 | 2003-09-16 | Xencor | Antibody optimization |
| WO2003083061A2 (en) | 2002-03-26 | 2003-10-09 | Centocor, Inc. | Anti-tnf antibodies, compositions, methods and uses |
| US7285269B2 (en) * | 2002-12-02 | 2007-10-23 | Amgen Fremont, Inc. | Antibodies directed to tumor necrosis factor |
-
2004
- 2004-11-25 GB GBGB0425972.7A patent/GB0425972D0/en not_active Ceased
-
2005
- 2005-11-24 ES ES05807990.6T patent/ES2553129T3/es not_active Expired - Lifetime
- 2005-11-24 JP JP2007542113A patent/JP2008521783A/ja not_active Abandoned
- 2005-11-24 WO PCT/GB2005/004511 patent/WO2006056779A2/en not_active Ceased
- 2005-11-24 US US11/791,498 patent/US9840556B2/en active Active
- 2005-11-24 EP EP05807990.6A patent/EP1817344B9/en not_active Expired - Lifetime