JP2005503146A5 - - Google Patents
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- Publication number
- JP2005503146A5 JP2005503146A5 JP2003520762A JP2003520762A JP2005503146A5 JP 2005503146 A5 JP2005503146 A5 JP 2005503146A5 JP 2003520762 A JP2003520762 A JP 2003520762A JP 2003520762 A JP2003520762 A JP 2003520762A JP 2005503146 A5 JP2005503146 A5 JP 2005503146A5
- Authority
- JP
- Japan
- Prior art keywords
- cell composition
- mesenchymal
- synovial fluid
- mesenchymal cells
- prepared
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 210000004027 cell Anatomy 0.000 description 39
- 239000000203 mixture Substances 0.000 description 23
- 238000000034 method Methods 0.000 description 21
- 210000001179 synovial fluid Anatomy 0.000 description 14
- 210000002901 mesenchymal stem cell Anatomy 0.000 description 5
- 230000007547 defect Effects 0.000 description 4
- 241001465754 Metazoa Species 0.000 description 3
- 210000001519 tissue Anatomy 0.000 description 3
- 102000004127 Cytokines Human genes 0.000 description 2
- 108090000695 Cytokines Proteins 0.000 description 2
- 102000010834 Extracellular Matrix Proteins Human genes 0.000 description 2
- 108010037362 Extracellular Matrix Proteins Proteins 0.000 description 2
- 210000000577 adipose tissue Anatomy 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000000988 bone and bone Anatomy 0.000 description 2
- 210000001185 bone marrow Anatomy 0.000 description 2
- 210000000845 cartilage Anatomy 0.000 description 2
- 238000004113 cell culture Methods 0.000 description 2
- 230000004069 differentiation Effects 0.000 description 2
- 210000002744 extracellular matrix Anatomy 0.000 description 2
- 239000003102 growth factor Substances 0.000 description 2
- 238000002347 injection Methods 0.000 description 2
- 239000007924 injection Substances 0.000 description 2
- 241001653121 Glenoides Species 0.000 description 1
- 239000005482 chemotactic factor Substances 0.000 description 1
- 230000035605 chemotaxis Effects 0.000 description 1
- 238000012258 culturing Methods 0.000 description 1
- 238000010353 genetic engineering Methods 0.000 description 1
- 239000007943 implant Substances 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10139783A DE10139783C1 (de) | 2001-08-14 | 2001-08-14 | Zellzusammensetzungen zur Behandlung von Osteoarthrose, sowie Verfahren zu deren Herstellung |
| PCT/EP2002/009080 WO2003015803A1 (de) | 2001-08-14 | 2002-08-13 | Zellzusammensetzungen zur behandlung von osteoarthrose, sowie verfahren zu deren herstellung |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005503146A JP2005503146A (ja) | 2005-02-03 |
| JP2005503146A5 true JP2005503146A5 (enExample) | 2006-01-05 |
Family
ID=7695336
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003520762A Pending JP2005503146A (ja) | 2001-08-14 | 2002-08-13 | 変形性関節症の治療に用いるための細胞組成物と、その製造方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20040241144A1 (enExample) |
| EP (1) | EP1418927A1 (enExample) |
| JP (1) | JP2005503146A (enExample) |
| DE (1) | DE10139783C1 (enExample) |
| WO (1) | WO2003015803A1 (enExample) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10333901A1 (de) * | 2003-07-21 | 2005-03-10 | Transtissue Technologies Gmbh | Verwendung von Chemokinen zur Rekrutierung von humanen mesenchymalen Vorläuferzellen zur Regeneration von Gelenkdefekten |
| KR101598947B1 (ko) * | 2004-09-24 | 2016-03-08 | 메소블라스트, 아이엔씨. | 간엽 전구세포의 증식 및/또는 생존성 증강 방법 |
| DE102005030614B4 (de) * | 2005-06-30 | 2014-05-08 | Biotissue Ag | Zellfreies Transplantat, dessen Verwendung, Verfahren zu dessen Herstellung, dabei hergestellte Matrix mit Gel und Verfahren zur Herstellung dieser Matrix mit Gel |
| EP1957633B1 (en) | 2005-10-13 | 2013-12-18 | Anthrogenesis Corporation | Immunomodulation using placental stem cells |
| US9598669B2 (en) | 2005-12-29 | 2017-03-21 | Anthrogenesis Corporation | Composition for collecting placental stem cells and methods of using the composition |
| WO2007079184A2 (en) * | 2005-12-29 | 2007-07-12 | Anthrogenesis Corporation | Co-culture of placental stem cells and stem cells from a second source |
| EP2471903B1 (en) | 2005-12-29 | 2018-02-14 | Anthrogenesis Corporation | Placental stem cell populations |
| NZ571127A (en) | 2006-03-07 | 2012-01-12 | Geeta Shroff | Compositions comprising human embryonic stem cells and their derivatives, methods of use, and methods of preparation |
| US7993918B2 (en) | 2006-08-04 | 2011-08-09 | Anthrogenesis Corporation | Tumor suppression using placental stem cells |
| DE102006047346A1 (de) | 2006-10-06 | 2008-04-10 | Transtissue Technologies Gmbh | Matrix-Gel-Transplantat ohne Zellen |
| JP2010518812A (ja) | 2007-02-12 | 2010-06-03 | アンスロジェネシス コーポレーション | 接着性胎盤幹細胞由来の肝細胞および軟骨細胞、ならびにｃｄ３４＋、ｃｄ４５−胎盤幹細胞の濃縮細胞集団 |
| PL2120977T3 (pl) | 2007-02-12 | 2013-12-31 | Anthrogenesis Corp | Leczenie chorób zapalnych z zastosowaniem łożyskowych komórek macierzystych |
| US8263065B2 (en) | 2007-09-28 | 2012-09-11 | Anthrogenesis Corporation | Tumor suppression using human placental perfusate and human placenta-derived intermediate natural killer cells |
| DK2329012T3 (da) | 2008-08-20 | 2020-08-24 | Celularity Inc | Behandling af slagtilfælde under anvendelse af isolerede placentaceller |
| EP3172963B1 (en) | 2008-08-20 | 2019-02-06 | Celularity, Inc. | Improved cell composition and methods of making the same |
| DK2331109T3 (da) | 2008-08-22 | 2013-09-08 | Anthrogenesis Corp | Fremgangsmåder og sammensætninger til behandling af knogledefekter med placentale cellepopulationer |
| RU2562154C2 (ru) | 2008-11-19 | 2015-09-10 | Антродженезис Корпорейшн | Амниотические адгезивные клетки |
| KR20120115602A (ko) | 2010-01-26 | 2012-10-18 | 안트로제네시스 코포레이션 | 태반 줄기 세포를 사용한 골 관련 암의 치료 |
| PT2556145T (pt) | 2010-04-07 | 2016-10-25 | Anthrogenesis Corp | Angiogénese usando células estaminais placentárias |
| EP2555783A1 (en) | 2010-04-08 | 2013-02-13 | Anthrogenesis Corporation | Treatment of sarcoidosis using placental stem cells |
| KR20230096132A (ko) | 2010-07-13 | 2023-06-29 | 셀룰래리티 인코포레이티드 | 천연 킬러 세포의 생성 방법 |
| US8969315B2 (en) | 2010-12-31 | 2015-03-03 | Anthrogenesis Corporation | Enhancement of placental stem cell potency using modulatory RNA molecules |
| US9040035B2 (en) | 2011-06-01 | 2015-05-26 | Anthrogenesis Corporation | Treatment of pain using placental stem cells |
| AU2012323963B2 (en) * | 2011-10-13 | 2017-10-12 | Solventum Intellectual Properties Company | Stimulation of cartilage repair using reduced pressure treatment |
| CN103961373A (zh) * | 2013-02-04 | 2014-08-06 | 西比曼生物科技（上海）有限公司 | 异体间质血管层细胞和异体间充质祖细胞在预防或治疗骨性关节炎中的应用 |
| JP2016506968A (ja) | 2013-02-05 | 2016-03-07 | アントフロゲネシス コーポレーション | 胎盤由来のナチュラルキラー細胞 |
| US20210047621A1 (en) | 2018-03-12 | 2021-02-18 | Universidade Do Porto | Compositions for use in the treatment of musculoskeletal conditions and methods for producing the same leveraging the synergistic activity of two different types of mesenchymal stromal/stem cells |
| CN108815187A (zh) * | 2018-07-20 | 2018-11-16 | 深圳市第二人民医院 | 一种包含人关节液外泌体的制剂及其使用方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5486359A (en) * | 1990-11-16 | 1996-01-23 | Osiris Therapeutics, Inc. | Human mesenchymal stem cells |
| CA2288690A1 (en) * | 1997-05-13 | 1998-11-19 | Osiris Therapeutics, Inc. | Osteoarthritis cartilage regeneration using human mesenchymal stem cells |
| US6835377B2 (en) * | 1998-05-13 | 2004-12-28 | Osiris Therapeutics, Inc. | Osteoarthritis cartilage regeneration |
| DE60143517D1 (de) * | 2000-04-25 | 2011-01-05 | Osiris Therapeutics Inc | Wiederherstellung der gelenken mit mesenchymalen stammzellen |
| US6800298B1 (en) * | 2000-05-11 | 2004-10-05 | Clemson University | Biological lubricant composition and method of applying lubricant composition |
-
2001
- 2001-08-14 DE DE10139783A patent/DE10139783C1/de not_active Expired - Fee Related
-
2002
- 2002-08-13 WO PCT/EP2002/009080 patent/WO2003015803A1/de not_active Ceased
- 2002-08-13 US US10/486,956 patent/US20040241144A1/en not_active Abandoned
- 2002-08-13 EP EP02764845A patent/EP1418927A1/de not_active Withdrawn
- 2002-08-13 JP JP2003520762A patent/JP2005503146A/ja active Pending
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