JP2005502344A5 - - Google Patents
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- Publication number
- JP2005502344A5 JP2005502344A5 JP2003523647A JP2003523647A JP2005502344A5 JP 2005502344 A5 JP2005502344 A5 JP 2005502344A5 JP 2003523647 A JP2003523647 A JP 2003523647A JP 2003523647 A JP2003523647 A JP 2003523647A JP 2005502344 A5 JP2005502344 A5 JP 2005502344A5
- Authority
- JP
- Japan
- Prior art keywords
- polypeptide
- seq
- polynucleotide
- isolated
- sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 108090000765 processed proteins & peptides Proteins 0.000 claims description 54
- 102000004196 processed proteins & peptides Human genes 0.000 claims description 52
- 210000004027 cell Anatomy 0.000 claims description 9
- 229920001184 polypeptide Polymers 0.000 claims 50
- 108091033319 polynucleotide Proteins 0.000 claims 33
- 102000040430 polynucleotide Human genes 0.000 claims 33
- 239000002157 polynucleotide Substances 0.000 claims 33
- 150000001875 compounds Chemical class 0.000 claims 9
- 238000000670 ligand binding assay Methods 0.000 claims 9
- 230000001747 exhibiting effect Effects 0.000 claims 8
- 239000000203 mixture Substances 0.000 claims 4
- 230000000694 effects Effects 0.000 claims 3
- 108020001507 fusion proteins Proteins 0.000 claims 3
- 102000037865 fusion proteins Human genes 0.000 claims 3
- 238000004519 manufacturing process Methods 0.000 claims 3
- 239000012528 membrane Substances 0.000 claims 3
- 238000000034 method Methods 0.000 claims 3
- 239000013604 expression vector Substances 0.000 claims 2
- 239000012634 fragment Substances 0.000 claims 2
- 238000012286 ELISA Assay Methods 0.000 claims 1
- 108060003951 Immunoglobulin Proteins 0.000 claims 1
- 230000004913 activation Effects 0.000 claims 1
- 210000000170 cell membrane Anatomy 0.000 claims 1
- 230000000295 complement effect Effects 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- 238000001514 detection method Methods 0.000 claims 1
- 239000001963 growth medium Substances 0.000 claims 1
- 102000018358 immunoglobulin Human genes 0.000 claims 1
- 230000005764 inhibitory process Effects 0.000 claims 1
- 238000002372 labelling Methods 0.000 claims 1
- 108020004999 messenger RNA Proteins 0.000 claims 1
- 238000012216 screening Methods 0.000 claims 1
- 238000010561 standard procedure Methods 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 description 3
- 108090000623 proteins and genes Proteins 0.000 description 3
- 101000604540 Homo sapiens PRKCA-binding protein Proteins 0.000 description 1
- 102100038730 PRKCA-binding protein Human genes 0.000 description 1
- 210000004899 c-terminal region Anatomy 0.000 description 1
- 210000002569 neuron Anatomy 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US31511101P | 2001-08-27 | 2001-08-27 | |
| PCT/EP2002/009518 WO2003018798A2 (en) | 2001-08-27 | 2002-08-26 | G-protein coupled receptor and dna sequences thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005502344A JP2005502344A (ja) | 2005-01-27 |
| JP2005502344A5 true JP2005502344A5 (https=) | 2006-01-05 |
Family
ID=23222935
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003523647A Pending JP2005502344A (ja) | 2001-08-27 | 2002-08-26 | 新規ｇタンパク質共役受容体およびそのｄｎａ配列 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US20050106659A1 (https=) |
| EP (1) | EP1423519A2 (https=) |
| JP (1) | JP2005502344A (https=) |
| AU (1) | AU2002331181A1 (https=) |
| WO (1) | WO2003018798A2 (https=) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012019168A2 (en) | 2010-08-06 | 2012-02-09 | Moderna Therapeutics, Inc. | Engineered nucleic acids and methods of use thereof |
| RU2013120302A (ru) | 2010-10-01 | 2014-11-20 | Модерна Терапьютикс, Инк. | Сконструированные нуклеиновые кислоты и способы их применения |
| EP2691101A2 (en) | 2011-03-31 | 2014-02-05 | Moderna Therapeutics, Inc. | Delivery and formulation of engineered nucleic acids |
| US9464124B2 (en) | 2011-09-12 | 2016-10-11 | Moderna Therapeutics, Inc. | Engineered nucleic acids and methods of use thereof |
| RU2648950C2 (ru) | 2011-10-03 | 2018-04-02 | Модерна Терапьютикс, Инк. | Модифицированные нуклеозиды, нуклеотиды и нуклеиновые кислоты и их применение |
| CN104114572A (zh) | 2011-12-16 | 2014-10-22 | 现代治疗公司 | 经修饰的核苷、核苷酸和核酸组合物 |
| AU2013243948A1 (en) | 2012-04-02 | 2014-10-30 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of proteins associated with human disease |
| US9572897B2 (en) | 2012-04-02 | 2017-02-21 | Modernatx, Inc. | Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins |
| US9254311B2 (en) | 2012-04-02 | 2016-02-09 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of proteins |
| US9283287B2 (en) | 2012-04-02 | 2016-03-15 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of nuclear proteins |
| WO2014081507A1 (en) | 2012-11-26 | 2014-05-30 | Moderna Therapeutics, Inc. | Terminally modified rna |
| US8980864B2 (en) | 2013-03-15 | 2015-03-17 | Moderna Therapeutics, Inc. | Compositions and methods of altering cholesterol levels |
| US10023626B2 (en) | 2013-09-30 | 2018-07-17 | Modernatx, Inc. | Polynucleotides encoding immune modulating polypeptides |
| JP2016538829A (ja) | 2013-10-03 | 2016-12-15 | モデルナ セラピューティクス インコーポレイテッドＭｏｄｅｒｎａ Ｔｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ． | 低密度リポタンパク質受容体をコードするポリヌクレオチド |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4946778A (en) * | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| US5011912A (en) * | 1986-12-19 | 1991-04-30 | Immunex Corporation | Hybridoma and monoclonal antibody for use in an immunoaffinity purification system |
| US5541087A (en) * | 1994-09-14 | 1996-07-30 | Fuji Immunopharmaceuticals Corporation | Expression and export technology of proteins as immunofusins |
| AU1208200A (en) * | 1998-10-15 | 2000-05-01 | Genetics Institute Inc. | Secreted expressed sequence tags (sests) |
| US20020038013A1 (en) * | 2000-02-04 | 2002-03-28 | Gregory Donoho | Novel human membrane proteins and polynucleotides encoding the same |
| US20030078407A1 (en) * | 2000-10-19 | 2003-04-24 | Smith Kelli E. | DNA encoding orphan SNORF53 receptor |
-
2002
- 2002-08-26 WO PCT/EP2002/009518 patent/WO2003018798A2/en not_active Ceased
- 2002-08-26 JP JP2003523647A patent/JP2005502344A/ja active Pending
- 2002-08-26 EP EP02767430A patent/EP1423519A2/en not_active Ceased
- 2002-08-26 AU AU2002331181A patent/AU2002331181A1/en not_active Abandoned
- 2002-08-26 US US10/485,006 patent/US20050106659A1/en not_active Abandoned
-
2007
- 2007-06-13 US US11/762,237 patent/US20070238135A1/en not_active Abandoned
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