JP2005500992A - アレルギーおよび喘息の治療用新規化合物 - Google Patents

アレルギーおよび喘息の治療用新規化合物 Download PDF

Info

Publication number
JP2005500992A
JP2005500992A JP2002577880A JP2002577880A JP2005500992A JP 2005500992 A JP2005500992 A JP 2005500992A JP 2002577880 A JP2002577880 A JP 2002577880A JP 2002577880 A JP2002577880 A JP 2002577880A JP 2005500992 A JP2005500992 A JP 2005500992A
Authority
JP
Japan
Prior art keywords
ige
fab
antibody
cells
mab
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2002577880A
Other languages
English (en)
Japanese (ja)
Inventor
ラフア，シルビア
ルー，ケネス・エイチ
シユペル，ボルフガング・エル
バレント，ペーター
クラフト，デイートリツヒ
バレンタ，ルドルフ
ヘイボン，エリク
アドリアンソン，ヨナス
グレンルンド，ハンス
Original Assignee
フアルマシア・ダイアグノステイクス・アー・ベー
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by フアルマシア・ダイアグノステイクス・アー・ベー filed Critical フアルマシア・ダイアグノステイクス・アー・ベー
Publication of JP2005500992A publication Critical patent/JP2005500992A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/16—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from plants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/42—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • C07K16/4283—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an allotypic or isotypic determinant on Ig
    • C07K16/4291—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an allotypic or isotypic determinant on Ig against IgE
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/54—F(ab')2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55—Fab or Fab'
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Pulmonology (AREA)
  • Botany (AREA)
  • Dermatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2002577880A 2001-03-28 2002-03-28 アレルギーおよび喘息の治療用新規化合物 Pending JP2005500992A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE0101093A SE0101093D0 (sv) 2001-03-28 2001-03-28 Novel compound for treatment of allergy and asthma
PCT/SE2002/000636 WO2002079257A1 (en) 2001-03-28 2002-03-28 Novel compound for treatment of allergy and asthma

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2013166370A Division JP2014012683A (ja) 2001-03-28 2013-08-09 アレルギーおよび喘息の治療用新規化合物

Publications (1)

Publication Number Publication Date
JP2005500992A true JP2005500992A (ja) 2005-01-13

Family

ID=20283563

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2002577880A Pending JP2005500992A (ja) 2001-03-28 2002-03-28 アレルギーおよび喘息の治療用新規化合物
JP2013166370A Pending JP2014012683A (ja) 2001-03-28 2013-08-09 アレルギーおよび喘息の治療用新規化合物

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2013166370A Pending JP2014012683A (ja) 2001-03-28 2013-08-09 アレルギーおよび喘息の治療用新規化合物

Country Status (7)

Country Link
US (2) US6986889B2 (https=)
EP (1) EP1373322A1 (https=)
JP (2) JP2005500992A (https=)
AU (1) AU2002251624B8 (https=)
CA (1) CA2441048C (https=)
SE (1) SE0101093D0 (https=)
WO (1) WO2002079257A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6884877B2 (en) 2001-10-03 2005-04-26 Florida State University Research Foundation, Inc. Purified linear epitopes from cashew nuts, nucleic acids encoding therefor, and associated methods
EP1941275B1 (en) 2005-09-29 2013-07-24 Medimmune, Inc. Method of identifying membrane lg specific antibodies and use thereof for targeting immunoglobulin-producing precursor cells
WO2015013668A1 (en) * 2013-07-26 2015-01-29 Ke Zhang Anti-immunoglobulin e antibodies and methods of use thereof
US20240182599A1 (en) * 2022-10-07 2024-06-06 Abwiz Bio, Inc. Anti-ige antibodies

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05199895A (ja) * 1991-12-24 1993-08-10 Snow Brand Milk Prod Co Ltd 抗ヒトＩｇＥ モノクローナル抗体
WO2000063252A1 (en) * 1999-04-14 2000-10-26 Novartis Ag Anti-idiotypic antibodies against antibodies which inhibit the binding of immunoglobuline to its high affinity receptor

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5449760A (en) * 1987-12-31 1995-09-12 Tanox Biosystems, Inc. Monoclonal antibodies that bind to soluble IGE but do not bind IGE on IGE expressing B lymphocytes or basophils
US5530101A (en) * 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
US6037453A (en) * 1995-03-15 2000-03-14 Genentech, Inc. Immunoglobulin variants
WO2000072879A1 (en) * 1999-05-26 2000-12-07 Tanox, Inc. TREATING ALLERGIC DISEASES WITH IMMUNOTHERAPY AND IgE ANTAGONISTS

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05199895A (ja) * 1991-12-24 1993-08-10 Snow Brand Milk Prod Co Ltd 抗ヒトＩｇＥ モノクローナル抗体
WO2000063252A1 (en) * 1999-04-14 2000-10-26 Novartis Ag Anti-idiotypic antibodies against antibodies which inhibit the binding of immunoglobuline to its high affinity receptor

Also Published As

Publication number Publication date
JP2014012683A (ja) 2014-01-23
AU2002251624B2 (en) 2008-09-04
US6986889B2 (en) 2006-01-17
AU2002251624A2 (en) 2008-05-01
US20030035796A1 (en) 2003-02-20
CA2441048C (en) 2011-12-13
SE0101093D0 (sv) 2001-03-28
CA2441048A1 (en) 2002-10-10
EP1373322A1 (en) 2004-01-02
WO2002079257A1 (en) 2002-10-10
AU2002251624B8 (en) 2008-10-02
USRE42324E1 (en) 2011-05-03

Similar Documents

Publication Publication Date Title
JP2021087432A (ja) トランスサイレチン（ｔｔｒ）アミロイドーシスに対する抗体療法及びそのためのヒト由来抗体
US6515110B1 (en) Multivalent antigen-binding proteins
US5869620A (en) Multivalent antigen-binding proteins
JP3925663B2 (ja) 抗Ｆａｓリガンド抗体および該抗体を用いた測定法
EP3753951A1 (en) Anti-b7-h4 antibody, antigen-binding fragment thereof and pharmaceutical use thereof
US20060063715A1 (en) Multivalent antigen-binding proteins
AU2003293096B9 (en) Humanized antibodies against monocyte chemotactic proteins
JP2014012683A (ja) アレルギーおよび喘息の治療用新規化合物
WO2022063281A1 (zh) 结合人il-33的抗体、其制备方法和用途
JPH05260990A (ja) モノクローナル抗体
WO2024113122A1 (en) An anti-il-8 antibody
CN115298216A (zh) 抗体或其抗原结合片段、其制备方法及医药用途
Laffer et al. A molecular model of type I allergy: Identification and characterization of a nonanaphylactic anti-human IgE antibody fragment that blocks the IgE-FcϵRI interaction and reacts with receptor-bound IgE
EP4023677A9 (en) Monoclonal antibody which targets tfpi
CN113366021A (zh) 糖基化Apo J特异性抗体及其用途
EP1101772B1 (en) Antibody specific to interleukin 18 precursor
CN112646029B (zh) 成熟脑源性神经营养因子的抗体及其应用和诊断试剂盒
AU2002251624A1 (en) Novel compound for treatment of allergy and asthma
Arilla et al. Quantification in mass units of group 1 grass allergens by a monoclonal antibody‐based sandwich ELISA
JP2003130880A (ja) 異常型プリオン免疫測定用試薬及びキット並びにそれを用いた異常型プリオンの免疫測定方法
JP3337523B2 (ja) β−Ｎ−アセチルグルコサミニダ−ゼのサンドイッチ免疫測定法、および該測定法に用いるモノクロ−ナル抗体
US20250313650A1 (en) Chi3l1 binding antibodies and antigen binding fragments thereof
CN118812704B (zh) 一种抗新型冠状病毒的四价中和抗体及其应用
Habibi-Anbouhi et al. Development and characterization of a new antipeptide monoclonal antibody directed to human CD20 antigen
KR20200049388A (ko) 페스트균의 f1 캡슐 단백질에 특이적으로 결합하는 단일클론항체, 상기 항체를 생산하는 하이브리도마 세포주 및 이의 용도

Legal Events

Date Code Title Description
A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20041025

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20080722

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20081015

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20081022

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20090122

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20100126

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20100525

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20100601

A911 Transfer to examiner for re-examination before appeal (zenchi)

Free format text: JAPANESE INTERMEDIATE CODE: A911

Effective date: 20100803

A912 Re-examination (zenchi) completed and case transferred to appeal board

Free format text: JAPANESE INTERMEDIATE CODE: A912

Effective date: 20101203

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20120510

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20120515

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20130501

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20130508

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20130809