JP2005320339A5 - - Google Patents

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Publication number
JP2005320339A5
JP2005320339A5 JP2005156477A JP2005156477A JP2005320339A5 JP 2005320339 A5 JP2005320339 A5 JP 2005320339A5 JP 2005156477 A JP2005156477 A JP 2005156477A JP 2005156477 A JP2005156477 A JP 2005156477A JP 2005320339 A5 JP2005320339 A5 JP 2005320339A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2005156477A
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Japanese (ja)
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JP2005320339A (ja
Filing date
Publication date
Application filed filed Critical
Publication of JP2005320339A publication Critical patent/JP2005320339A/ja
Publication of JP2005320339A5 publication Critical patent/JP2005320339A5/ja
Withdrawn legal-status Critical Current

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JP2005156477A 1998-10-07 2005-05-27 改変型ＴＧＦ−βスーパーファミリータンパク質 Withdrawn JP2005320339A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10341898P 1998-10-07 1998-10-07
US37533399A 1999-08-16 1999-08-16

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2000574560A Division JP3762222B2 (ja) 1998-10-07 1999-10-07 改変型ＴＧＦ−βスーパーファミリータンパク質

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2008162608A Division JP2008231125A (ja) 1998-10-07 2008-06-20 改変型ＴＧＦ−βスーパーファミリータンパク質

Publications (2)

Publication Number Publication Date
JP2005320339A JP2005320339A (ja) 2005-11-17
JP2005320339A5 true JP2005320339A5 (enExample) 2006-04-13

Family

ID=26800442

Family Applications (6)

Application Number Title Priority Date Filing Date
JP2000574560A Expired - Fee Related JP3762222B2 (ja) 1998-10-07 1999-10-07 改変型ＴＧＦ−βスーパーファミリータンパク質
JP2005156477A Withdrawn JP2005320339A (ja) 1998-10-07 2005-05-27 改変型ＴＧＦ−βスーパーファミリータンパク質
JP2008162608A Withdrawn JP2008231125A (ja) 1998-10-07 2008-06-20 改変型ＴＧＦ−βスーパーファミリータンパク質
JP2010098044A Withdrawn JP2010180241A (ja) 1998-10-07 2010-04-21 改変型ＴＧＦ−βスーパーファミリータンパク質
JP2012200388A Pending JP2013014606A (ja) 1998-10-07 2012-09-12 改変型ＴＧＦ−βスーパーファミリータンパク質
JP2016000135A Pending JP2016056185A (ja) 1998-10-07 2016-01-04 改変型ＴＧＦ−βスーパーファミリータンパク質

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2000574560A Expired - Fee Related JP3762222B2 (ja) 1998-10-07 1999-10-07 改変型ＴＧＦ−βスーパーファミリータンパク質

Family Applications After (4)

Application Number Title Priority Date Filing Date
JP2008162608A Withdrawn JP2008231125A (ja) 1998-10-07 2008-06-20 改変型ＴＧＦ−βスーパーファミリータンパク質
JP2010098044A Withdrawn JP2010180241A (ja) 1998-10-07 2010-04-21 改変型ＴＧＦ−βスーパーファミリータンパク質
JP2012200388A Pending JP2013014606A (ja) 1998-10-07 2012-09-12 改変型ＴＧＦ−βスーパーファミリータンパク質
JP2016000135A Pending JP2016056185A (ja) 1998-10-07 2016-01-04 改変型ＴＧＦ−βスーパーファミリータンパク質

Country Status (6)

Country Link
US (2) US20050250936A1 (enExample)
EP (2) EP1117805A2 (enExample)
JP (6) JP3762222B2 (enExample)
AU (1) AU1103900A (enExample)
CA (2) CA2345024C (enExample)
WO (1) WO2000020449A2 (enExample)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2378925C (en) * 1999-07-21 2010-04-06 University Of Southern California Matrix-targeted fusion polypeptides for tissue regeneration and wound healing
US6942853B2 (en) 2001-01-09 2005-09-13 Queen Mary And Westfield College Latent fusion protein
US7141392B2 (en) 2001-01-09 2006-11-28 Queen Mary And Westfield College Latent fusion protein
JP2002306163A (ja) * 2001-04-11 2002-10-22 Chemo Sero Therapeut Res Inst 大腸菌を宿主とする遺伝子組換えヒトトロンビンの調製方法
FI116827B (fi) 2001-08-24 2006-03-15 Univ Zuerich Luun morfogeneettisen proteiinin deleetiomutantti, sitä sisältävä farmaseuttinen koostumus ja sen käyttö
PT2441466E (pt) 2004-04-13 2014-09-09 St Vincents Hosp Sydney Agente de inibição de mic-1
US20090042780A1 (en) * 2004-05-20 2009-02-12 Acceleron Pharma Inc Modified TGF-Beta Superfamily Polypeptides and Related Methods
US7795389B2 (en) 2004-09-28 2010-09-14 The Board Of Regents Of The University Of Texas System Antagonizing TGF-beta activity with various ectodomains TGF-beta receptors used in combination or as fusion proteins
US20080199443A1 (en) * 2005-06-09 2008-08-21 The Govt. Of The U.S.A. As Represented By The Secretary, Dept. Of Health And Human Services Bone Morphogenetic Variants, Compositions and Methods of Treatment
ATE514712T1 (de) * 2005-12-26 2011-07-15 Yantai Zhenghai Bio Technology Co Ltd Aktivierte collagen-gerüstmaterialien und ihre speziellen kondensierten aktiven restorationsfaktoren
WO2008051526A2 (en) * 2006-10-23 2008-05-02 Stryker Corporation Bone morphogenetic proteins
ES2447516T3 (es) 2006-12-21 2014-03-12 Stryker Corporation Formulaciones de liberación sostenida que comprenden cristales BMP-7
CA2751445C (en) 2009-02-06 2018-06-19 Pepscan Systems B.V. Truncated cystine-knot proteins
JP5819734B2 (ja) 2009-02-12 2015-11-24 ストライカー コーポレイションＳｔｒｙｋｅｒ Ｃｏｒｐｏｒａｔｉｏｎ ＴＧＦ−βスーパーファミリーメンバー含有タンパク質の最小に侵襲性の全身送達のための組成物および方法
CA2752157A1 (en) 2009-02-12 2010-08-19 Stryker Corporation Peripheral administration of proteins including tgf-.beta. superfamily members for systemic treatment of disorders and disease
US20120148539A1 (en) 2009-03-24 2012-06-14 Moulay Hicham Alaoui-Ismaili Methods and Compositions for Tissue Engineering
WO2011031856A1 (en) 2009-09-09 2011-03-17 Stryker Corporation Bmp -7 for use in treating pain induced by injuries and diseases of an articular joint
ES2387379T3 (es) 2009-09-17 2012-09-21 Stryker Corporation Tampones para controlar el pH de las proteínas morfogenéticas óseas
AU2010341565A1 (en) 2009-12-22 2012-07-12 Stryker Corporation BMP-7 variants with reduced immunogenicity
US8592364B2 (en) * 2010-02-11 2013-11-26 Ecole Polytechnique Federale de Lausanne (“EPFL”) CCR7 ligand delivery and co-delivery in immunotherapy
US11078248B2 (en) 2010-03-19 2021-08-03 Lifenet Health BMP peptides and methods of use
CA2794167A1 (en) 2010-03-24 2011-09-29 Lifenet Health Bmp-7 peptides & methods of use
US9850296B2 (en) 2010-08-10 2017-12-26 Ecole Polytechnique Federale De Lausanne (Epfl) Erythrocyte-binding therapeutics
US9517257B2 (en) 2010-08-10 2016-12-13 Ecole Polytechnique Federale De Lausanne (Epfl) Erythrocyte-binding therapeutics
CA2807942C (en) 2010-08-10 2021-07-27 Ecole Polytechnique Federale De Lausanne Erythrocyte-binding therapeutics
CN103079585B (zh) * 2010-08-20 2015-09-30 惠氏有限责任公司 经设计的成骨蛋白
US9688735B2 (en) * 2010-08-20 2017-06-27 Wyeth Llc Designer osteogenic proteins
US9856305B2 (en) 2010-08-20 2018-01-02 Wyeth Llc Designer osteogenic proteins
AU2013220079B2 (en) 2012-02-15 2017-10-05 Ecole Polytechnique Federale De Lausanne Erythrocyte-binding therapeutics
MX370720B (es) 2012-12-21 2019-12-20 Aveo Pharmaceuticals Inc Anticuerpos anti-gdf15.
SMT202100008T1 (it) 2013-05-06 2021-03-15 Scholar Rock Inc Composizioni e metodi per la modulazione di fattore di crescita
US10953101B2 (en) 2014-02-21 2021-03-23 École Polytechnique Fédérale De Lausanne (Epfl) Glycotargeting therapeutics
CA2946064C (en) 2014-02-21 2023-09-26 Ecole Polytechnique Federale De Lausanne (Epfl) Glycotargeting therapeutics
US10946079B2 (en) 2014-02-21 2021-03-16 Ecole Polytechnique Federale De Lausanne Glycotargeting therapeutics
US10046056B2 (en) 2014-02-21 2018-08-14 École Polytechnique Fédérale De Lausanne (Epfl) Glycotargeting therapeutics
EP3341397B1 (en) * 2015-08-25 2024-12-18 Histide AG Compounds for inducing tissue formation and uses thereof
CN109311956A (zh) 2015-08-25 2019-02-05 伊斯迪德股份公司 诱导组织形成的化合物及其应用
US11512126B2 (en) 2016-05-31 2022-11-29 Mogam Institute For Biomedicak Research AB6 family designer ligands of TGF-β superfamily
US11253579B2 (en) 2017-06-16 2022-02-22 The University Of Chicago Compositions and methods for inducing immune tolerance
AU2019265734B2 (en) 2018-05-09 2026-03-19 Anokion Sa Compositions and methods concerning immune tolerance
WO2020095894A1 (ja) 2018-11-05 2020-05-14 味の素株式会社 フローマイクロリアクターを用いるリフォールディングされたタンパク質の製造方法及びタンパク質のリフォールディング装置
CN115128147B (zh) * 2021-03-29 2025-02-11 盛禾(中国)生物制药有限公司 一种融合蛋白样品的快速分析方法
KR20250133922A (ko) * 2023-01-12 2025-09-09 리제너론 파아마슈티컬스, 인크. TGFβ의 표적화된 전달을 위한 조성물 및 방법

Family Cites Families (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1985002198A1 (en) * 1983-11-01 1985-05-23 Amgen Microbial expression of type i transforming growth factor, polypeptide analogs thereof and hybrid egf/tgf polypeptides
US5106748A (en) 1986-07-01 1992-04-21 Genetics Institute, Inc. Dna sequences encoding 5 proteins
US5108922A (en) 1986-07-01 1992-04-28 Genetics Institute, Inc. DNA sequences encoding BMP-1 products
US5013649A (en) 1986-07-01 1991-05-07 Genetics Institute, Inc. DNA sequences encoding osteoinductive products
US4877864A (en) 1987-03-26 1989-10-31 Genetics Institute, Inc. Osteoinductive factors
ZA874681B (en) 1986-07-01 1988-04-27 Genetics Inst Novel osteoinductive factors
US5155058A (en) 1986-11-07 1992-10-13 Canon Kabushiki Kaisha Method of making semiconductor memory device
US5221620A (en) * 1987-10-06 1993-06-22 Oncogen Cloning and expression of transforming growth factor β2
WO1989003886A1 (en) * 1987-10-30 1989-05-05 Oncogen, A Limited Partnership Expression systems for preparation of polypeptides in prokaryotic cells
US5250302A (en) 1988-04-08 1993-10-05 Stryker Corporation Osteogenic devices
US5266683A (en) 1988-04-08 1993-11-30 Stryker Corporation Osteogenic proteins
US5011691A (en) 1988-08-15 1991-04-30 Stryker Corporation Osteogenic devices
US5258494A (en) 1988-04-08 1993-11-02 Stryker Corporation Osteogenic proteins
US4968590A (en) 1988-04-08 1990-11-06 Stryker Corporation Osteogenic proteins and polypeptides
US5002965A (en) 1989-05-09 1991-03-26 Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R.A.S.) Use of ginkgolides to prevent reperfusion injury in organ transplantation
ATE167486T1 (de) 1989-10-17 1998-07-15 Stryker Corp Osteogene vorrichtungen
CA2070393A1 (en) * 1989-10-18 1991-04-19 Charles M. Cohen Biosynthetic constructs of tgf-beta
GB8927546D0 (en) 1989-12-06 1990-02-07 Ciba Geigy Process for the production of biologically active tgf-beta
WO1992000318A1 (en) * 1990-06-25 1992-01-09 Oncogene Science, Inc. Tissue-derived tumor growth inhibitors, methods for preparation and uses thereof
DK0575555T3 (da) 1991-03-11 2001-11-05 Curis Inc Proteininduceret morfogenese
DE69233022T2 (de) * 1991-11-04 2004-02-12 Genetics Institute, LLC, Cambridge Rekombinante knochenmorphogenetische protein heterodimere, zusammensetzungen und verfahren zur verwendung
US5807713A (en) * 1992-02-12 1998-09-15 Biopharm Gesellschaft Zur Biotechnologischen Entwicklung DNA encoding growth/differentiation factor
EP0666868B2 (en) 1992-10-28 2006-06-14 Genentech, Inc. Use of anti-VEGF antibodies for the treatment of cancer
EP1439190A1 (en) 1993-01-12 2004-07-21 The Johns Hopkins University School Of Medicine Growth differentiation factor-5
CA2124422A1 (en) * 1993-05-27 1994-11-28 Yukio Fujisawa Heterodimers of tgf-.beta. superfamily
JPH09503903A (ja) 1993-07-09 1997-04-22 ザ ジョーンズ ホプキンス ユニバーシティー スクール オブ メディシン 増殖分化因子−６
AU689184B2 (en) 1993-12-07 1998-03-26 Genetics Institute, Llc BMP-12, BMP-13 and tendon-inducing compositions thereof
US5399677A (en) 1993-12-07 1995-03-21 Genetics Institute, Inc. Mutants of bone morphogenetic proteins
TW459044B (en) * 1994-07-01 2001-10-11 Bioph Biotech Entw Pharm Gmbh Protein MP-121 of the TGF-β-like family
US6352972B1 (en) * 1995-06-06 2002-03-05 Marcel E. Nimni Bone morphogenetic proteins and their use in bone growth
US5800811A (en) * 1995-06-06 1998-09-01 Hall; Frederick L. Artificial skin prepared from coclagen matrix containing transforming growth factor-β having a collagen binding site
US5674292A (en) 1995-06-07 1997-10-07 Stryker Corporation Terminally sterilized osteogenic devices and preparation thereof
US5932716A (en) 1995-07-26 1999-08-03 Creative Biomolecules, Inc. Morphogen-responsive regulatory elements
US6677432B1 (en) * 1998-10-07 2004-01-13 Stryker Corporation Mutations of the C-terminal portion of TGF-β superfamily proteins
AU2009243094B2 (en) 2006-11-06 2015-02-12 Massachusetts Institute Of Technology Immunomodulating compositions and methods of use thereof
US8750953B2 (en) 2008-02-19 2014-06-10 Covidien Lp Methods and systems for alerting practitioners to physiological conditions
RU2510423C2 (ru) 2009-08-31 2014-03-27 Ниппон Стил Корпорейшн Высокопрочная гальванизированная листовая сталь и способ ее изготовления
WO2013033216A1 (en) 2011-08-29 2013-03-07 Massachusetts Institute Of Technology System and method for finding mood-dependent top selling/rated list
US9107654B2 (en) 2012-01-05 2015-08-18 Cook Medical Technologies Llc Attachment device for tissue approximation and retraction

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