JP2005239692A - 包装体入りトラニラスト含有医薬組成物 - Google Patents
包装体入りトラニラスト含有医薬組成物 Download PDFInfo
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- JP2005239692A JP2005239692A JP2004055447A JP2004055447A JP2005239692A JP 2005239692 A JP2005239692 A JP 2005239692A JP 2004055447 A JP2004055447 A JP 2004055447A JP 2004055447 A JP2004055447 A JP 2004055447A JP 2005239692 A JP2005239692 A JP 2005239692A
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- Prior art keywords
- tranilast
- package
- pharmaceutical composition
- light
- weight
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Abstract
【解決手段】 一般式(1)で表される化合物及び/又は一般式(2)で表される化合物を含有する包装体に、トラニラスト又はその塩を含有する医薬製剤を収容してなる、包装体入り医薬製剤。
【選択図】 なし
Description
項1.一般式(1)で表される化合物
よりなる群から選択される少なくとも1種の化合物又はその金属レーキを含有する包装体に、トラニラスト又はその塩を含有する医薬組成物を収容してなる、包装体入り医薬組成物。
項2.医薬組成物が水性組成物である、項1に記載の包装体入り医薬組成物。
項3.医薬製剤が、点眼剤、洗眼剤、注射剤、皮膚外用剤、点鼻剤又はコンタクトレンズ用剤である、項1又は2に記載の包装体入り医薬製剤。
項4.包装体が透明部分を有しているものである、項1乃至3のいずれかに記載の包装体入り医薬組成物。
項5.トラニラスト又はその塩の光による分解を抑制する方法であって、
一般式(1)で表される化合物
よりなる群から選択される少なくとも1種の化合物又はその金属レーキを含有する包装体に、トラニラスト又はその塩を含有する医薬組成物を収容することを特徴とする光分解抑制方法。
試験例1
表1の処方例1に示すトラニラスト含有組成物を調製し、これを0.2μmメンブランフィルターにてろ過した。
表3に示すトラニラスト含有点眼剤を調製した。また別途、ポリプロピレン樹脂中に、0.05重量%の割合で一般式(1)で表される化合物のアルミニウムレーキを練り込み、これを用いて点眼剤用透明容器を調製した。上記トラニラスト含有点眼剤を上記透明容器に収容して、透明容器入りトラニラスト含有点眼剤を調製した。得られた透明容器入りトラニラスト含有点眼剤は、光の暴露によっても、容器内部のトラニラストの光による分解が顕著に抑制されていることが確認された。
Claims (5)
- 医薬組成物が水性組成物である、請求項1に記載の包装体入り医薬組成物。
- 医薬製剤が、点眼剤、洗眼剤、注射剤、皮膚外用剤、点鼻剤又はコンタクトレンズ用剤である、請求項1又は2に記載の包装体入り医薬製剤。
- 包装体が透明部分を有しているものである、請求項1乃至3のいずれかに記載の包装体入り医薬組成物。
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Citations (1)
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JPS5832821A (ja) * | 1981-08-20 | 1983-02-25 | Sumitomo Bakelite Co Ltd | 光分解性医薬品を収納した遮光性包装物 |
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JPS5832821A (ja) * | 1981-08-20 | 1983-02-25 | Sumitomo Bakelite Co Ltd | 光分解性医薬品を収納した遮光性包装物 |
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