JP2005218447A5 - - Google Patents
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- Publication number
- JP2005218447A5 JP2005218447A5 JP2005019619A JP2005019619A JP2005218447A5 JP 2005218447 A5 JP2005218447 A5 JP 2005218447A5 JP 2005019619 A JP2005019619 A JP 2005019619A JP 2005019619 A JP2005019619 A JP 2005019619A JP 2005218447 A5 JP2005218447 A5 JP 2005218447A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- nucleic acid
- acid molecule
- isolated nucleic
- modified
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 102000016600 Inosine-5'-monophosphate dehydrogenases Human genes 0.000 claims 20
- 108050006182 Inosine-5'-monophosphate dehydrogenases Proteins 0.000 claims 20
- 229920001184 polypeptide Polymers 0.000 claims 19
- 102000004196 processed proteins & peptides Human genes 0.000 claims 19
- 108090000765 processed proteins & peptides Proteins 0.000 claims 19
- 102000039446 nucleic acids Human genes 0.000 claims 14
- 108020004707 nucleic acids Proteins 0.000 claims 14
- 150000007523 nucleic acids Chemical class 0.000 claims 14
- 210000004027 cell Anatomy 0.000 claims 6
- 150000001413 amino acids Chemical group 0.000 claims 5
- 239000013598 vector Substances 0.000 claims 5
- 230000000295 complement effect Effects 0.000 claims 3
- HNDVDQJCIGZPNO-UHFFFAOYSA-N histidine Natural products OC(=O)C(N)CC1=CN=CN1 HNDVDQJCIGZPNO-UHFFFAOYSA-N 0.000 claims 3
- 239000002773 nucleotide Substances 0.000 claims 3
- 125000003729 nucleotide group Chemical group 0.000 claims 3
- 239000013604 expression vector Substances 0.000 claims 2
- 241000894006 Bacteria Species 0.000 claims 1
- 241000588724 Escherichia coli Species 0.000 claims 1
- 241000238631 Hexapoda Species 0.000 claims 1
- GRSZFWQUAKGDAV-KQYNXXCUSA-N IMP Chemical class O[C@@H]1[C@H](O)[C@@H](COP(O)(O)=O)O[C@H]1N1C(NC=NC2=O)=C2N=C1 GRSZFWQUAKGDAV-KQYNXXCUSA-N 0.000 claims 1
- 101710130167 Mannitol-1-phosphate 5-dehydrogenase Proteins 0.000 claims 1
- 240000004808 Saccharomyces cerevisiae Species 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- 230000002538 fungal effect Effects 0.000 claims 1
- 238000002955 isolation Methods 0.000 claims 1
- 210000004962 mammalian cell Anatomy 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims 1
- 230000000717 retained effect Effects 0.000 claims 1
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/769,481 US7276362B2 (en) | 2004-01-30 | 2004-01-30 | Recombinant histidine-tagged inosine monophosphate dehydrogenase polypeptides |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010053103A Division JP2010119395A (ja) | 2004-01-30 | 2010-03-10 | 修飾イノシン一リン酸デヒドロゲナーゼ |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005218447A JP2005218447A (ja) | 2005-08-18 |
| JP2005218447A5 true JP2005218447A5 (https=) | 2006-06-08 |
| JP4597689B2 JP4597689B2 (ja) | 2010-12-15 |
Family
ID=34654391
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2005019619A Expired - Lifetime JP4597689B2 (ja) | 2004-01-30 | 2005-01-27 | 修飾イノシン一リン酸デヒドロゲナーゼ |
| JP2010053103A Pending JP2010119395A (ja) | 2004-01-30 | 2010-03-10 | 修飾イノシン一リン酸デヒドロゲナーゼ |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010053103A Pending JP2010119395A (ja) | 2004-01-30 | 2010-03-10 | 修飾イノシン一リン酸デヒドロゲナーゼ |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US7276362B2 (https=) |
| EP (1) | EP1559779B1 (https=) |
| JP (2) | JP4597689B2 (https=) |
| AT (1) | ATE424451T1 (https=) |
| CA (1) | CA2491887C (https=) |
| DE (1) | DE602005013013D1 (https=) |
| DK (1) | DK1559779T3 (https=) |
| ES (1) | ES2322477T3 (https=) |
| PL (1) | PL1559779T3 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7473541B2 (en) * | 2004-07-09 | 2009-01-06 | Gross Richard W | Identification, cloning, expression, and purification of three novel human calcium-independent phospholipase A2 family members possessing triacylglycerol lipase and acylglycerol transacylase activities |
| US7183106B1 (en) * | 2004-05-28 | 2007-02-27 | The United States Of America As Represented By The United States Department Of Energy | Bacterial inosine 5′-monophosphate dehydrogenase (“IMPDH”) DNA as a dominant selectable marker in mammals and other eukaryotes |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4215051A (en) | 1979-08-29 | 1980-07-29 | Standard Oil Company (Indiana) | Formation, purification and recovery of phthalic anhydride |
| CA1304886C (en) | 1986-07-10 | 1992-07-07 | Heinz Dobeli | Metal chelate resins |
| US5047513A (en) | 1986-07-10 | 1991-09-10 | Hoffmann-La Roche Inc. | Metal chelate resins |
| CA1340522C (en) | 1987-03-10 | 1999-05-04 | Heinz Dobeli | Fusion proteins containing neighbouring histidines for improved purification |
| US5665583A (en) | 1988-08-12 | 1997-09-09 | Arch Dev Corp | Methods and materials relating to IMPDH and GMP production |
| US5283257A (en) | 1992-07-10 | 1994-02-01 | The Board Of Trustees Of The Leland Stanford Junior University | Method of treating hyperproliferative vascular disease |
| WO1994012184A1 (en) | 1992-11-24 | 1994-06-09 | Syntex (U.S.A.) Inc. | Use of mycophenolic acid, mycophenolate mofetil or derivate thereof to inhibit stenosis |
| US5380879A (en) | 1994-02-18 | 1995-01-10 | Syntex (U.S.A.) Inc. | Derivatives of mycophenolic acid |
| US5444072A (en) | 1994-02-18 | 1995-08-22 | Syntex (U.S.A.) Inc. | 6-substituted mycophenolic acid and derivatives |
| US5807876A (en) | 1996-04-23 | 1998-09-15 | Vertex Pharmaceuticals Incorporated | Inhibitors of IMPDH enzyme |
| US6128582A (en) | 1996-04-30 | 2000-10-03 | Vertex Pharmaceuticals Incorporated | Molecules comprising an IMPDH-like binding pocket and encoded data storage medium capable of graphically displaying them |
| DE19811313A1 (de) | 1998-03-16 | 1999-09-23 | Merckle Gmbh | Verfahren zur Bestimmung der Aktivität von Inosin 5'-monophosphat dehydrogenase |
| US6451572B1 (en) | 1998-06-25 | 2002-09-17 | Cornell Research Foundation, Inc. | Overexpression of phytase genes in yeast systems |
| US6107052A (en) | 1999-06-09 | 2000-08-22 | Roche Diagnostics Corporation | Enzymatic measurement of mycophenolic acid |
| US6524808B1 (en) | 1999-06-25 | 2003-02-25 | Roche Diagnostics Corporation | Enzyme inhibition immunoassay |
| PL354805A1 (en) | 1999-11-18 | 2004-02-23 | Cornell Research Foundation, Inc. | Site-directed mutagenesis of escherichia coli |
| JP2004514409A (ja) | 2000-05-10 | 2004-05-20 | ブリストル−マイヤーズ スクイブ カンパニー | 修飾イノシン５’−一リン酸デヒドロゲナーゼポリペプチドおよびその用途 |
| DE60140929D1 (de) | 2000-11-14 | 2010-02-11 | Roche Diagnostics Gmbh | Immunoassay für HIV-Protease-Hemstoffe |
-
2004
- 2004-01-30 US US10/769,481 patent/US7276362B2/en not_active Expired - Lifetime
-
2005
- 2005-01-25 AT AT05001460T patent/ATE424451T1/de active
- 2005-01-25 ES ES05001460T patent/ES2322477T3/es not_active Expired - Lifetime
- 2005-01-25 PL PL05001460T patent/PL1559779T3/pl unknown
- 2005-01-25 DK DK05001460T patent/DK1559779T3/da active
- 2005-01-25 EP EP05001460A patent/EP1559779B1/en not_active Expired - Lifetime
- 2005-01-25 DE DE602005013013T patent/DE602005013013D1/de not_active Expired - Lifetime
- 2005-01-27 CA CA2491887A patent/CA2491887C/en not_active Expired - Lifetime
- 2005-01-27 JP JP2005019619A patent/JP4597689B2/ja not_active Expired - Lifetime
-
2007
- 2007-06-20 US US11/820,662 patent/US7531336B2/en not_active Expired - Lifetime
-
2010
- 2010-03-10 JP JP2010053103A patent/JP2010119395A/ja active Pending
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