JP2005080553A5 - - Google Patents
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- Publication number
- JP2005080553A5 JP2005080553A5 JP2003315306A JP2003315306A JP2005080553A5 JP 2005080553 A5 JP2005080553 A5 JP 2005080553A5 JP 2003315306 A JP2003315306 A JP 2003315306A JP 2003315306 A JP2003315306 A JP 2003315306A JP 2005080553 A5 JP2005080553 A5 JP 2005080553A5
- Authority
- JP
- Japan
- Prior art keywords
- hhase
- hydantoin compound
- unreacted
- type
- compound remains
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Description
光学特異性のＨＨａｓｅを用いて５置換ヒダントイン化合物を加水分解すると、基質とならないエナンチオマーが未反応のまま残る。すなわち、Ｄ−ＨＨａｓｅを用いた場合、Ｌ体ヒダントイン化合物が未反応状態で残り、Ｌ−ＨＨａｓｅを用いた場合、Ｄ体ヒダントイン化合物が未反応状態で残る。
Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2003315306A JP4452914B2 (ja) | 2003-09-08 | 2003-09-08 | 新規トランスポータタンパク質 |
| PCT/JP2004/013066 WO2005038021A1 (ja) | 2003-09-08 | 2004-09-08 | 新規トランスポータタンパク質 |
| EP04787749A EP1666588B1 (en) | 2003-09-08 | 2004-09-08 | Novel transporter protein |
| US11/276,614 US7320794B2 (en) | 2003-09-08 | 2006-03-08 | Transporter protein |
| US11/946,113 US7851610B2 (en) | 2003-09-08 | 2007-11-28 | Transporter protein |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2003315306A JP4452914B2 (ja) | 2003-09-08 | 2003-09-08 | 新規トランスポータタンパク質 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005080553A JP2005080553A (ja) | 2005-03-31 |
| JP2005080553A5 true JP2005080553A5 (ja) | 2006-10-12 |
| JP4452914B2 JP4452914B2 (ja) | 2010-04-21 |
Family
ID=34415622
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003315306A Expired - Fee Related JP4452914B2 (ja) | 2003-09-08 | 2003-09-08 | 新規トランスポータタンパク質 |
Country Status (4)
| Country | Link |
|---|---|
| US (2) | US7320794B2 (ja) |
| EP (1) | EP1666588B1 (ja) |
| JP (1) | JP4452914B2 (ja) |
| WO (1) | WO2005038021A1 (ja) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4877227B2 (ja) * | 2005-05-20 | 2012-02-15 | 味の素株式会社 | Ｌ−セリン誘導体の製造方法およびこれに用いる酵素 |
| JP4806963B2 (ja) * | 2005-05-20 | 2011-11-02 | 味の素株式会社 | β−ヒドロキシアミノ酸の製造方法およびこれに用いる酵素 |
| WO2009091045A1 (ja) * | 2008-01-18 | 2009-07-23 | Ajinomoto Co., Inc. | セリン誘導体の製造方法及びこれに用いるタンパク質 |
| JPWO2009139392A1 (ja) * | 2008-05-12 | 2011-09-22 | 味の素株式会社 | β−アラニルアミノ酸またはその誘導体の製造方法 |
| US9688967B2 (en) | 2014-12-05 | 2017-06-27 | Synlogic, Inc. | Bacteria engineered to treat diseases associated with hyperammonemia |
| TW201632516A (zh) | 2014-12-11 | 2016-09-16 | 哈佛大學校長及研究員協會 | 細胞壞死抑制劑與相關方法 |
| IL296538A (en) | 2015-05-13 | 2022-11-01 | Synlogic Operating Co Inc | A genetically engineered bacterium to lower hyperphenylamine |
| EP3294757B1 (en) * | 2015-05-13 | 2023-12-27 | Synlogic Operating Company, Inc. | Bacteria engineered to treat a disease or disorder |
| US11883439B2 (en) | 2015-05-13 | 2024-01-30 | Synlogic Operating Company, Inc. | Bacteria engineered to treat a disease or disorder |
| CA3005451A1 (en) | 2015-11-16 | 2017-05-26 | Synlogic Operating Company, Inc. | Bacteria engineered to reduce hyperphenylalaninemia |
| AU2018290278B2 (en) | 2017-06-21 | 2022-12-15 | Synlogic Operating Company, Inc. | Bacteria for the treatment of disorders |
| IL295353A (en) | 2020-03-20 | 2022-10-01 | Synlogic Operating Co Inc | Genetically engineered microorganisms to reduce hyperphenylalaninemia |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999051722A2 (de) * | 1998-04-02 | 1999-10-14 | Degussa-Hüls Aktiengesellschaft | Rekombinante l-n-carbamoylase aus arthrobacter aurescens, verfahren zur herstellung von l-aminosäuren mittels dieser |
| US6713288B1 (en) * | 1999-09-28 | 2004-03-30 | University Of Stuttgart | Whole cell catalysts |
| JP3814126B2 (ja) | 2000-06-30 | 2006-08-23 | ジヤトコ株式会社 | 自動変速機の入力クラッチ潤滑制御装置 |
| ATE512217T1 (de) * | 2000-09-13 | 2011-06-15 | Ajinomoto Kk | 5-substituerte hydantoin racemase, dafür kodierende dna, und verfahren zur herstellung optisch aktiver aminosäure |
| JP4529338B2 (ja) * | 2001-03-08 | 2010-08-25 | 味の素株式会社 | ヒダントイナーゼをコードするｄｎａ、ｎ−カルバミル−ｌ−アミノ酸ハイドロラーゼをコードするｄｎａ、組み換えｄｎａ、形質転換された細胞、タンパク質の製造方法および光学活性アミノ酸の製造方法 |
| JP4485734B2 (ja) * | 2002-01-22 | 2010-06-23 | 味の素株式会社 | ５置換ヒダントインラセマーゼ、これをコードするｄｎａ、組み換えｄｎａ、形質転換された細胞および光学活性アミノ酸の製造方法 |
| WO2005087941A1 (ja) | 2004-03-17 | 2005-09-22 | Ajinomoto Co., Inc. | Ｌ−フクロースの製造方法およびｌ−フコースの製造方法 |
| JP4806963B2 (ja) | 2005-05-20 | 2011-11-02 | 味の素株式会社 | β−ヒドロキシアミノ酸の製造方法およびこれに用いる酵素 |
-
2003
- 2003-09-08 JP JP2003315306A patent/JP4452914B2/ja not_active Expired - Fee Related
-
2004
- 2004-09-08 EP EP04787749A patent/EP1666588B1/en not_active Expired - Fee Related
- 2004-09-08 WO PCT/JP2004/013066 patent/WO2005038021A1/ja active Application Filing
-
2006
- 2006-03-08 US US11/276,614 patent/US7320794B2/en not_active Expired - Fee Related
-
2007
- 2007-11-28 US US11/946,113 patent/US7851610B2/en not_active Expired - Fee Related
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