JP2004533481A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2004533481A5 JP2004533481A5 JP2003510423A JP2003510423A JP2004533481A5 JP 2004533481 A5 JP2004533481 A5 JP 2004533481A5 JP 2003510423 A JP2003510423 A JP 2003510423A JP 2003510423 A JP2003510423 A JP 2003510423A JP 2004533481 A5 JP2004533481 A5 JP 2004533481A5
- Authority
- JP
- Japan
- Prior art keywords
- protecting group
- hydrogen
- formula
- compound
- carboxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP01810670 | 2001-07-06 | ||
| PCT/EP2002/007308 WO2003004455A2 (en) | 2001-07-06 | 2002-07-02 | Process for the preparation of 7-amino syn 3,5-dihydroxy heptanoic acid derivatives, intermediates thereof and methods for their preparation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004533481A JP2004533481A (ja) | 2004-11-04 |
| JP2004533481A5 true JP2004533481A5 (https=) | 2005-12-22 |
Family
ID=41546668
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003510423A Pending JP2004533481A (ja) | 2001-07-06 | 2002-07-02 | ７−アミノｓｙｎ３，５−ジヒドロキシヘプタン酸誘導体の製造方法、それらの中間体及び中間体の製造方法 |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US7317123B2 (https=) |
| EP (1) | EP1404642B1 (https=) |
| JP (1) | JP2004533481A (https=) |
| AT (1) | ATE457972T1 (https=) |
| AU (1) | AU2002328835A1 (https=) |
| CA (1) | CA2453211A1 (https=) |
| CZ (1) | CZ2004158A3 (https=) |
| DE (1) | DE60235365D1 (https=) |
| DK (1) | DK1404642T3 (https=) |
| HR (1) | HRP20040117A2 (https=) |
| HU (1) | HUP0401006A2 (https=) |
| IL (1) | IL159718A0 (https=) |
| PL (1) | PL367774A1 (https=) |
| SK (1) | SK792004A3 (https=) |
| WO (1) | WO2003004455A2 (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002057229A1 (en) | 2001-01-19 | 2002-07-25 | Biocon India Limited | FORM V CRYSTALLINE [R-(R*,R*)]-2-(4-FLUOROPHENYL)-ß,$G(D)-DIHYDROXY-5-(1-METHYLETHYL)-3-PHENYL-4-[(PHENYLAMINO)CARBONYL]-1H-PYRROLE-1- HEPTANOIC ACID HEMI CALCIUM SALT. (ATORVASTATIN) |
| CN1610657A (zh) | 2001-07-06 | 2005-04-27 | 西巴特殊化学品控股有限公司 | 制备用于合成他汀类衍生物、特别是7－氨基3,5－二羟基庚酸衍生物的中间体的方法,及其中间体 |
| US7361772B2 (en) | 2001-08-16 | 2008-04-22 | Biocon Limited | Process for the production of atorvastatin calcium |
| HUP0500074A3 (en) | 2002-03-18 | 2005-07-28 | Biocon Ltd Bangalore | Amorphous hmg-coa reductase inhibitors of desired particle size and process for producing them |
| US7179942B2 (en) | 2002-07-05 | 2007-02-20 | Bicon Limited | Halo-substituted active methylene compounds |
| SI1631533T1 (sl) | 2003-04-22 | 2009-08-31 | Bicon Ltd | Nov postopek za stereoselektivno redukcijo beta - ketoestrov |
| KR20070092994A (ko) | 2003-06-18 | 2007-09-14 | 테바 파마슈티컬 인더스트리즈 리미티드 | 플루바스타틴 나트륨 결정형 ｘｉｖ, ｌｘｘｉｉｉ,ｌｘｘｉｘ, ｌｘｘｘ 및 ｌｘｘｘｖｉｉ, 이의 제조 방법,이를 포함하는 조성물 및 이를 사용하는 방법 |
| US7368468B2 (en) | 2003-06-18 | 2008-05-06 | Teva Pharmaceutical Industries Ltd. | Fluvastatin sodium crystal forms XIV, LXXIII, LXXIX, LXXX and LXXXVII, processes for preparing them, compositions containing them and methods of using them |
| WO2005026107A1 (en) | 2003-09-18 | 2005-03-24 | Biocon Limited | Novel process for the preparation of tert-butyl 6-cyano-5-hydroxy-3-oxohexanoate |
| US7851624B2 (en) | 2003-12-24 | 2010-12-14 | Teva Pharamaceutical Industries Ltd. | Triol form of rosuvastatin and synthesis of rosuvastatin |
| WO2007022488A2 (en) | 2005-08-16 | 2007-02-22 | Teva Pharmaceutical Industries Ltd. | Crystalline rosuvastatin intermediate |
| EP2778229A1 (de) | 2013-03-11 | 2014-09-17 | Sandoz Ag | Verfahren zur enantioselektiven Herstellung von 3-Hydroxyglutarsäuremonoestern und deren Verwendung |
| CN103361386B (zh) * | 2013-06-28 | 2015-04-15 | 苏州汉酶生物技术有限公司 | 一种罗素伐他汀中间体的制备方法 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5003080A (en) | 1988-02-22 | 1991-03-26 | Warner-Lambert Company | Process for trans-6-(2-(substituted-pyrrol-1-yl)alkyl)pryan-2-one inhibitors of cholesterol synthesis |
| US5097045A (en) | 1989-02-01 | 1992-03-17 | Warner-Lambert Company | Process for trans-6-[2-(substituted-pyrrol-1-yl)alkyl]pyran-2-one inhibitors of cholesterol synthesis |
| IT1226726B (it) * | 1988-07-29 | 1991-02-05 | Zambon Spa | Composti attivi come inibitori della biosintesi del colesterolo. |
| JPH02115234A (ja) | 1988-10-26 | 1990-04-27 | Tdk Corp | 架橋ポリフッ化ビニリデンの製造方法 |
| DE69009237T2 (de) | 1989-02-27 | 1994-12-01 | Takasago Perfumery Co Ltd | Verfahren zur Herstellung von optisch aktiven Estern der 6-t-Butoxy-3,5-dihydroxyhexansäure. |
| JPH0791223B2 (ja) * | 1989-02-27 | 1995-10-04 | 高砂香料工業株式会社 | 光学活性６―ｔ―ブトキシ―３，５―ジヒドロキシヘキサン酸エステルの製造法 |
| IT1237792B (it) | 1989-12-21 | 1993-06-17 | Zambon Spa | Composti attivi come inibitori dell'enzima hmg-coa reduttasi |
| US5051502A (en) * | 1990-06-06 | 1991-09-24 | University Of Notre Dame Du Lac | Rhodium catalyzed cyclization process for bicyclic β-lactams |
| US5248793A (en) | 1990-10-17 | 1993-09-28 | Warner-Lambert Company | Process for the synthesis of (4R-cis)-1,1-dimethylethyl 6-iodomethyl or 6-(phenyl-substituted)sulfonyloxymethyl-2,2-dimethyl-1,3-dioxane-4-acetate |
| US5155251A (en) | 1991-10-11 | 1992-10-13 | Warner-Lambert Company | Process for the synthesis of (5R)-1,1-dimethylethyl-6-cyano-5-hydroxy-3-oxo-hexanoate |
| US5298627A (en) | 1993-03-03 | 1994-03-29 | Warner-Lambert Company | Process for trans-6-[2-(substituted-pyrrol-1-yl)alkyl]pyran-2-one inhibitors of cholesterol synthesis |
| JP3652394B2 (ja) * | 1995-01-27 | 2005-05-25 | 高砂香料工業株式会社 | Ｎ−置換−７−アミノ−５−ヒドロキシ−３−オキソヘプタン酸誘導体およびその製造法 |
| ES2284219T3 (es) * | 1997-12-19 | 2007-11-01 | Pfizer Ireland Pharmaceuticals | Procedimiento de sintesis de 1,3-dioles. |
| DE19920784A1 (de) | 1999-05-05 | 2000-11-09 | Bayer Ag | Stilbenaufheller |
-
2002
- 2002-07-02 DK DK02764615.7T patent/DK1404642T3/da active
- 2002-07-02 IL IL15971802A patent/IL159718A0/xx unknown
- 2002-07-02 SK SK79-2004A patent/SK792004A3/sk not_active Application Discontinuation
- 2002-07-02 PL PL02367774A patent/PL367774A1/xx unknown
- 2002-07-02 WO PCT/EP2002/007308 patent/WO2003004455A2/en not_active Ceased
- 2002-07-02 HU HU0401006A patent/HUP0401006A2/hu unknown
- 2002-07-02 AU AU2002328835A patent/AU2002328835A1/en not_active Abandoned
- 2002-07-02 CA CA002453211A patent/CA2453211A1/en not_active Abandoned
- 2002-07-02 JP JP2003510423A patent/JP2004533481A/ja active Pending
- 2002-07-02 AT AT02764615T patent/ATE457972T1/de not_active IP Right Cessation
- 2002-07-02 US US10/482,946 patent/US7317123B2/en not_active Expired - Fee Related
- 2002-07-02 DE DE60235365T patent/DE60235365D1/de not_active Expired - Fee Related
- 2002-07-02 EP EP02764615A patent/EP1404642B1/en not_active Expired - Lifetime
- 2002-07-02 HR HR20040117A patent/HRP20040117A2/hr not_active Application Discontinuation
- 2002-07-02 CZ CZ2004158A patent/CZ2004158A3/cs unknown
-
2007
- 2007-11-16 US US11/941,347 patent/US7504532B2/en not_active Expired - Fee Related
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US7692034B2 (en) | Process for the preparation of 7-amino syn 3,5-dihydroxy heptanoic acid derivatives via 6-cyano syn 3,5-dihydroxy hexanoic acid derivatives | |
| US8026383B2 (en) | Process for the preparation of intermediates useful in the synthesis of statin derivatives | |
| US7504532B2 (en) | Process for the preparation of 7-amino syn 3,5-dihydroxy heptanoic acid derivatives, intermediates thereof and methods for their preparation | |
| AU2002354701A1 (en) | Process for the preparation of intermediates useful in the synthesis of statin derivatives especially 7-amino 3,5-dihydroxy heptanoic acid derivatives, and intermediates thereof | |
| JP2004533481A5 (https=) | ||
| US20050014954A1 (en) | Pyrrole synthesis |