JP2004533434A5 - - Google Patents
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- Publication number
- JP2004533434A5 JP2004533434A5 JP2002584700A JP2002584700A JP2004533434A5 JP 2004533434 A5 JP2004533434 A5 JP 2004533434A5 JP 2002584700 A JP2002584700 A JP 2002584700A JP 2002584700 A JP2002584700 A JP 2002584700A JP 2004533434 A5 JP2004533434 A5 JP 2004533434A5
- Authority
- JP
- Japan
- Prior art keywords
- therapeutic agent
- tegafur
- uracil
- dose
- day
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 239000003814 drug Substances 0.000 claims 9
- 229940124597 therapeutic agent Drugs 0.000 claims 9
- ISAKRJDGNUQOIC-UHFFFAOYSA-N Uracil Chemical compound O=C1C=CNC(=O)N1 ISAKRJDGNUQOIC-UHFFFAOYSA-N 0.000 claims 6
- VVIAGPKUTFNRDU-UHFFFAOYSA-N 6S-folinic acid Natural products C1NC=2NC(N)=NC(=O)C=2N(C=O)C1CNC1=CC=C(C(=O)NC(CCC(O)=O)C(O)=O)C=C1 VVIAGPKUTFNRDU-UHFFFAOYSA-N 0.000 claims 5
- MPJKWIXIYCLVCU-UHFFFAOYSA-N Folinic acid Natural products NC1=NC2=C(N(C=O)C(CNc3ccc(cc3)C(=O)NC(CCC(=O)O)CC(=O)O)CN2)C(=O)N1 MPJKWIXIYCLVCU-UHFFFAOYSA-N 0.000 claims 5
- VVIAGPKUTFNRDU-ABLWVSNPSA-N folinic acid Chemical compound C1NC=2NC(N)=NC(=O)C=2N(C=O)C1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 VVIAGPKUTFNRDU-ABLWVSNPSA-N 0.000 claims 5
- 235000008191 folinic acid Nutrition 0.000 claims 5
- 239000011672 folinic acid Substances 0.000 claims 5
- 229960001691 leucovorin Drugs 0.000 claims 5
- WFWLQNSHRPWKFK-ZCFIWIBFSA-N tegafur Chemical compound O=C1NC(=O)C(F)=CN1[C@@H]1OCCC1 WFWLQNSHRPWKFK-ZCFIWIBFSA-N 0.000 claims 5
- 229960001674 tegafur Drugs 0.000 claims 5
- CMSMOCZEIVJLDB-UHFFFAOYSA-N Cyclophosphamide Chemical compound ClCCN(CCCl)P1(=O)NCCCO1 CMSMOCZEIVJLDB-UHFFFAOYSA-N 0.000 claims 4
- 229960004397 cyclophosphamide Drugs 0.000 claims 4
- DHMYGZIEILLVNR-UHFFFAOYSA-N 5-fluoro-1-(oxolan-2-yl)pyrimidine-2,4-dione;1h-pyrimidine-2,4-dione Chemical compound O=C1C=CNC(=O)N1.O=C1NC(=O)C(F)=CN1C1OCCC1 DHMYGZIEILLVNR-UHFFFAOYSA-N 0.000 claims 3
- 150000003839 salts Chemical class 0.000 claims 3
- 229940035893 uracil Drugs 0.000 claims 3
- 241001465754 Metazoa Species 0.000 claims 2
- 206010028980 Neoplasm Diseases 0.000 claims 2
- 206010006187 Breast cancer Diseases 0.000 claims 1
- 208000026310 Breast neoplasm Diseases 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US28672901P | 2001-04-26 | 2001-04-26 | |
| PCT/US2002/012769 WO2002087335A1 (en) | 2001-04-26 | 2002-04-22 | Method for treating tumors by the administration of tegafur, uracil, folinic acid, and cyclophosphamide |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004533434A JP2004533434A (ja) | 2004-11-04 |
| JP2004533434A5 true JP2004533434A5 (https=) | 2005-12-22 |
Family
ID=23099905
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002584700A Withdrawn JP2004533434A (ja) | 2001-04-26 | 2002-04-22 | テガフール、ウラシル、フォリン酸およびシクロホスファミドの投与による腫瘍の治療方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6620816B2 (https=) |
| EP (1) | EP1399021A1 (https=) |
| JP (1) | JP2004533434A (https=) |
| CA (1) | CA2445262A1 (https=) |
| CZ (1) | CZ20032835A3 (https=) |
| HU (1) | HUP0303953A3 (https=) |
| MX (1) | MXPA03009681A (https=) |
| NO (1) | NO20034690L (https=) |
| PL (1) | PL373247A1 (https=) |
| WO (1) | WO2002087335A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1798689B1 (en) * | 2001-06-26 | 2008-12-03 | Sony Corporation | Image processing apparatus and method, and image-capturing apparatus |
| JP4596220B2 (ja) | 2001-06-26 | 2010-12-08 | ソニー株式会社 | 画像処理装置および方法、記録媒体、並びにプログラム |
| US7951780B2 (en) * | 2004-02-25 | 2011-05-31 | Astellas Pharma Inc. | Antitumor agent |
| JP2006160664A (ja) * | 2004-12-07 | 2006-06-22 | Vitamin C60 Bioresearch Kk | フリーラジカル疾患予防治療用組成物 |
| CN101657203B (zh) * | 2007-03-02 | 2012-09-05 | 卧龙岗大学 | 抗癌药的组合物及递送方法 |
| US20160067182A1 (en) * | 2013-04-09 | 2016-03-10 | Merrimack Pharmaceuticals, Inc. | Methods and compositions for improving outcomes of liposomal chemotherapy |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4328229A (en) | 1978-03-29 | 1982-05-04 | Taiho Pharmaceutical Company Limited | Anti-cancer composition for delivering 5-fluorouracil to cancer tissues |
| US5534513A (en) * | 1991-09-05 | 1996-07-09 | Taiho Pharmaceutical Company, Ltd. | Antitumor potentiator and antitumor composition |
| US5688773A (en) * | 1994-08-17 | 1997-11-18 | The General Hospital Corporation | Method of selectively destroying neoplastic cells |
-
2002
- 2002-04-19 US US10/126,745 patent/US6620816B2/en not_active Expired - Fee Related
- 2002-04-22 CZ CZ20032835A patent/CZ20032835A3/cs unknown
- 2002-04-22 EP EP02766793A patent/EP1399021A1/en not_active Withdrawn
- 2002-04-22 MX MXPA03009681A patent/MXPA03009681A/es unknown
- 2002-04-22 WO PCT/US2002/012769 patent/WO2002087335A1/en not_active Ceased
- 2002-04-22 CA CA002445262A patent/CA2445262A1/en not_active Abandoned
- 2002-04-22 JP JP2002584700A patent/JP2004533434A/ja not_active Withdrawn
- 2002-04-22 PL PL02373247A patent/PL373247A1/xx not_active Application Discontinuation
- 2002-04-22 HU HU0303953A patent/HUP0303953A3/hu unknown
-
2003
- 2003-10-20 NO NO20034690A patent/NO20034690L/no not_active Application Discontinuation
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