JP2002326936A5 - - Google Patents
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- Publication number
- JP2002326936A5 JP2002326936A5 JP2001361167A JP2001361167A JP2002326936A5 JP 2002326936 A5 JP2002326936 A5 JP 2002326936A5 JP 2001361167 A JP2001361167 A JP 2001361167A JP 2001361167 A JP2001361167 A JP 2001361167A JP 2002326936 A5 JP2002326936 A5 JP 2002326936A5
- Authority
- JP
- Japan
- Prior art keywords
- transfer agent
- methylol transfer
- fluorouracil
- colorectal cancer
- taurultam
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical class OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 claims 12
- GHASVSINZRGABV-UHFFFAOYSA-N Fluorouracil Chemical compound FC1=CNC(=O)NC1=O GHASVSINZRGABV-UHFFFAOYSA-N 0.000 claims 8
- 229960002949 fluorouracil Drugs 0.000 claims 8
- 239000003795 chemical substances by application Substances 0.000 claims 6
- 206010009944 Colon cancer Diseases 0.000 claims 4
- 208000001333 Colorectal Neoplasms Diseases 0.000 claims 4
- 239000003814 drug Substances 0.000 claims 3
- 229940124597 therapeutic agent Drugs 0.000 claims 3
- RJGYJMFQWGPBGM-UHFFFAOYSA-N 1,2,4-thiadiazinane 1,1-dioxide Chemical compound O=S1(=O)CCNCN1 RJGYJMFQWGPBGM-UHFFFAOYSA-N 0.000 claims 2
- 206010027476 Metastases Diseases 0.000 claims 2
- 230000002401 inhibitory effect Effects 0.000 claims 2
- 230000009401 metastasis Effects 0.000 claims 2
- 239000000203 mixture Substances 0.000 claims 2
- AJKIRUJIDFJUKJ-UHFFFAOYSA-N taurolidine Chemical group C1NS(=O)(=O)CCN1CN1CNS(=O)(=O)CC1 AJKIRUJIDFJUKJ-UHFFFAOYSA-N 0.000 claims 2
- 229960004267 taurolidine Drugs 0.000 claims 2
- 229950007343 taurultam Drugs 0.000 claims 2
- 230000005907 cancer growth Effects 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US25313800P | 2000-11-28 | 2000-11-28 | |
| US60/253138 | 2000-11-28 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009235501A Division JP2010043115A (ja) | 2000-11-28 | 2009-10-09 | 腫瘍転移および癌の治療における５−フルオロウラシルの有効性の増強 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2002326936A JP2002326936A (ja) | 2002-11-15 |
| JP2002326936A5 true JP2002326936A5 (https=) | 2005-07-14 |
Family
ID=22959032
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001361167A Pending JP2002326936A (ja) | 2000-11-28 | 2001-11-27 | 腫瘍転移および癌の治療における５−フルオロウラシルの有効性の増強 |
| JP2009235501A Pending JP2010043115A (ja) | 2000-11-28 | 2009-10-09 | 腫瘍転移および癌の治療における５−フルオロウラシルの有効性の増強 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009235501A Pending JP2010043115A (ja) | 2000-11-28 | 2009-10-09 | 腫瘍転移および癌の治療における５−フルオロウラシルの有効性の増強 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20020111328A1 (https=) |
| EP (1) | EP1208840B1 (https=) |
| JP (2) | JP2002326936A (https=) |
| AT (1) | ATE352307T1 (https=) |
| CA (1) | CA2363973C (https=) |
| DE (1) | DE60126225T2 (https=) |
| ES (1) | ES2278702T3 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060199811A1 (en) * | 1997-07-31 | 2006-09-07 | Pfirrmann Rolf W | Method of treatment for preventing or reducing tumor growth in the liver of patient |
| US20030027818A1 (en) * | 2001-04-03 | 2003-02-06 | Redmond H. Paul | Treatment of cancers |
| US20050124608A1 (en) * | 2001-04-03 | 2005-06-09 | Redmond H. P. | Treatment of cancers |
| US8304390B2 (en) | 1997-07-31 | 2012-11-06 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Method of treatment for preventing or reducing tumor growth in the liver of patient |
| US8030301B2 (en) | 1999-06-04 | 2011-10-04 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Treatment of cancers with methylol-containing compounds and at least one electrolyte |
| US7892530B2 (en) * | 1999-06-04 | 2011-02-22 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Treatment of tumor metastases and cancer |
| US7345039B2 (en) * | 1999-06-04 | 2008-03-18 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Enhancement of effectiveness of 5-fluorouracil in treatment of tumor metastases and cancer |
| EP1450814B1 (en) * | 2001-10-01 | 2016-11-30 | Geistlich Pharma AG | Methods of inhibiting metastases |
| WO2008112144A1 (en) * | 2007-03-07 | 2008-09-18 | University Of Medicine And Dentistry Of New Jersey | Modulation of drug sensitivity |
| US20190381060A1 (en) | 2016-01-11 | 2019-12-19 | Cormedix Inc. | Taurolidine treatment for myc-expressing tumors in mammalian bodies |
| JP2021535163A (ja) * | 2018-08-28 | 2021-12-16 | コーメディクス・インコーポレーテッド | タウロリジン加水分解産物による神経芽細胞腫治療 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9015108D0 (en) * | 1990-07-09 | 1990-08-29 | Geistlich Soehne Ag | Chemical compositions |
| GB9716219D0 (en) * | 1997-07-31 | 1997-10-08 | Geistlich Soehne Ag | Prevention of metastases |
| US6479481B1 (en) * | 1999-06-04 | 2002-11-12 | Ed. Geistlich Soehne Ag Fur Chemische Industrie | Methods and compositions for treating primary and secondary tumors of the central nervous system (CNS) |
-
2001
- 2001-11-26 CA CA002363973A patent/CA2363973C/en not_active Expired - Fee Related
- 2001-11-27 JP JP2001361167A patent/JP2002326936A/ja active Pending
- 2001-11-27 US US09/993,896 patent/US20020111328A1/en not_active Abandoned
- 2001-11-28 DE DE60126225T patent/DE60126225T2/de not_active Expired - Lifetime
- 2001-11-28 EP EP01309983A patent/EP1208840B1/en not_active Expired - Lifetime
- 2001-11-28 AT AT01309983T patent/ATE352307T1/de not_active IP Right Cessation
- 2001-11-28 ES ES01309983T patent/ES2278702T3/es not_active Expired - Lifetime
-
2009
- 2009-10-09 JP JP2009235501A patent/JP2010043115A/ja active Pending
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