JP2004532885A - 眼内の過免疫応答を処置するための組成物および方法 - Google Patents

眼内の過免疫応答を処置するための組成物および方法 Download PDF

Info

Publication number
JP2004532885A
JP2004532885A JP2003501497A JP2003501497A JP2004532885A JP 2004532885 A JP2004532885 A JP 2004532885A JP 2003501497 A JP2003501497 A JP 2003501497A JP 2003501497 A JP2003501497 A JP 2003501497A JP 2004532885 A JP2004532885 A JP 2004532885A
Authority
JP
Japan
Prior art keywords
antibody
antibodies
eye
gamma
compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2003501497A
Other languages
English (en)
Japanese (ja)
Other versions
JP2004532885A5 (enExample
Inventor
スカーコビチ,シモン
スカーコビチ,ボリス
Original Assignee
アドバンスド・バイオセラピー・インコーポレーテツド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by アドバンスド・バイオセラピー・インコーポレーテツド filed Critical アドバンスド・バイオセラピー・インコーポレーテツド
Publication of JP2004532885A publication Critical patent/JP2004532885A/ja
Publication of JP2004532885A5 publication Critical patent/JP2004532885A5/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
JP2003501497A 2001-06-05 2002-06-04 眼内の過免疫応答を処置するための組成物および方法 Pending JP2004532885A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US29589501P 2001-06-05 2001-06-05
US09/894,287 US6534059B2 (en) 2001-06-05 2001-06-28 Compositions and methods for treating hyperimmune response in the eye
PCT/US2002/017677 WO2002098460A1 (en) 2001-06-05 2002-06-04 Compositions and methods for treating hyperimmune response in the eye

Publications (2)

Publication Number Publication Date
JP2004532885A true JP2004532885A (ja) 2004-10-28
JP2004532885A5 JP2004532885A5 (enExample) 2006-01-05

Family

ID=26969391

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2003501497A Pending JP2004532885A (ja) 2001-06-05 2002-06-04 眼内の過免疫応答を処置するための組成物および方法

Country Status (8)

Country Link
US (2) US6534059B2 (enExample)
EP (1) EP1401496B1 (enExample)
JP (1) JP2004532885A (enExample)
AT (1) ATE343398T1 (enExample)
AU (1) AU2002318175B2 (enExample)
CA (1) CA2449488C (enExample)
DE (1) DE60215649D1 (enExample)
WO (1) WO2002098460A1 (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
US6709655B2 (en) * 2001-02-28 2004-03-23 Instituto Bioclon, S.A. De C.V. Pharmaceutical composition of F(ab1)2 antibody fragments and a process for the preparation thereof
US6861056B2 (en) * 2001-06-05 2005-03-01 Advanced Biotherapy, Inc. Compositions and methods for treating hyperimmune response in the eye
US6534059B2 (en) * 2001-06-05 2003-03-18 Advanced Biotherapy, Inc. Compositions and methods for treating hyperimmune response in the eye
US6712976B2 (en) * 2001-09-13 2004-03-30 Abtech Industries, Inc. Dual-action decontamination system
US7335759B2 (en) 2002-12-02 2008-02-26 Universidad Nacional Autónoma de Méxica (UNAM) Recombinant immunogens for the generation of antivenoms to the venom of scorpions of the genus Centruroides
MXPA06000965A (es) * 2003-07-25 2007-05-04 Silanes Sa De Cv Lab Administracion de fragmentos f(ab??)2 de anticuerpos anti-citocinas.
MX2007008719A (es) 2005-01-27 2007-09-11 Novimmune Sa Anticuerpos anti-interferon gamma y metodos de uso de los mismos.
US20100003264A1 (en) * 2005-03-24 2010-01-07 Washington University Reduction of Ophthalmalogic Neovascularization
US7381802B2 (en) * 2005-04-15 2008-06-03 Universidad Nacional Autónoma De México (UNAM) Human antibodies that specifically recognize the toxin Cn2 from Centruroides noxius scorpion venom
CN101489569A (zh) * 2006-06-12 2009-07-22 席拉坎有限责任公司 眼表面疾病的局部治疗
WO2010019839A1 (en) * 2008-08-15 2010-02-18 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Methods for using interferon gamma to absorb fluid from the subretinal space
US11091543B2 (en) 2015-05-07 2021-08-17 Swedish Orphan Biovitrum Ag Methods, compositions and dosing regimens for treating or preventing interferon-gamma related indications
JP2018515493A (ja) 2015-05-07 2018-06-14 ノビミューン エスアー Cxcl9および他のバイオマーカーのレベルが上昇した患者における障害の診断および治療のための方法および組成物

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4704362A (en) 1977-11-08 1987-11-03 Genentech, Inc. Recombinant cloning vehicle microbial polypeptide expression
JP2523562B2 (ja) 1985-10-25 1996-08-14 ザイモジェネティックス インコーポレーテッド 外来タンパク質を分泌することを目的としたbar1の使用法
DE3689123T2 (de) 1985-11-01 1994-03-03 Xoma Corp Modulare einheit von antikörpergenen, daraus hergestellte antikörper und verwendung.
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
GB8905400D0 (en) * 1989-03-09 1989-04-19 Jonker Margreet Medicaments
AU2777092A (en) * 1991-10-04 1993-05-03 United States Of America, Represented By The Secretary, Department Of Health And Human Services, The Treatment of ocular inflammation by blockage of cell adhesion molecules
US5888511A (en) 1993-02-26 1999-03-30 Advanced Biotherapy Concepts, Inc. Treatment of autoimmune diseases, including AIDS
DE19535073C1 (de) * 1995-09-21 1997-02-20 Roland Dr Grosmann Verfahren zur künstlichen Inkubation von Hühnereiern
US6861056B2 (en) * 2001-06-05 2005-03-01 Advanced Biotherapy, Inc. Compositions and methods for treating hyperimmune response in the eye
US6534059B2 (en) * 2001-06-05 2003-03-18 Advanced Biotherapy, Inc. Compositions and methods for treating hyperimmune response in the eye

Also Published As

Publication number Publication date
US20020182212A1 (en) 2002-12-05
EP1401496A1 (en) 2004-03-31
US20030224005A1 (en) 2003-12-04
US6534059B2 (en) 2003-03-18
DE60215649D1 (de) 2006-12-07
AU2002318175B2 (en) 2006-01-05
EP1401496A4 (en) 2005-08-31
WO2002098460A1 (en) 2002-12-12
ATE343398T1 (de) 2006-11-15
HK1063601A1 (en) 2005-01-07
CA2449488A1 (en) 2002-12-12
US7232568B2 (en) 2007-06-19
EP1401496B1 (en) 2006-10-25
CA2449488C (en) 2010-02-09

Similar Documents

Publication Publication Date Title
CA2637917C (en) Therapeutic agents for diseases involving choroidal neovascularization
JP3383303B2 (ja) CDw52−多発性硬化症の治療のための特異抗体
RU2565399C2 (ru) Фармацевтическая композиция, составленная для локального нанесения на поверхность барьера эпителиальной ткани, содержащая антитела, которые проходят через этот барьер
EP1651266B1 (en) Administration of anti-tnf-alpha f(ab')2 antibody fragments
CA2449488C (en) Compositions and methods for treating hyperimmune response in the eye
US6967106B2 (en) Human medical treatment by aerosol inhalation of immunoglobulin A
WO2009014263A1 (ja) インターロイキン6受容体阻害剤を有効成分とする眼炎症疾患治療剤
EA017945B1 (ru) Композиции и способы лечения и профилактики состояний фиброза, воспаления и неоваскуляризации глаза животного
US20100322947A1 (en) Pharmaceutical composition for treating avellino cornea dystrophy comprising an antibody against tgf-beta
AU2002318175A1 (en) Compositions and methods for treating hyperimmune response in the eye
US20040086508A1 (en) Treatment of organ transplant rejection
US6861056B2 (en) Compositions and methods for treating hyperimmune response in the eye
HU211059B (en) Method for producing pharmaceutical compositions usable for reducing immunglobulin e responses, containing human il-4 antibodies
DE69029858T2 (de) Behandlung von einer autoimmun-krankheit
JPH078805B2 (ja) 眼の発育の神経ペプチド制御
US20040062768A1 (en) Compositions and methods for treating hyperimmune response in the eye
EP0282343A2 (en) Method to stimulate the immune response to specific antigens
CA2272605A1 (en) Pharmaceutical composition containing gp34 binding-inhibitory agent as effective ingredient
US20050152902A1 (en) Treatment of diabetic retinopathy
WO2005117987A1 (en) Antibody conjugates targeting to ocular proteins
HK1063601B (en) Compositions and methods for treating hyperimmune response in the eye
TW202607019A (zh) 通過單域抗體對神經退化性疾病之抑制
JP2528549B2 (ja) ヒトil―2レセプタ―重鎖に結合する新規モノクロ―ナル抗体
JP2019509060A (ja) 抗CD11d抗体およびその使用
HK1140695A (en) Pharmaceutical composition, comprising an anti-cd6 monoclonal antibody used in the diagnosis and treatment of rheumatoid arthritis

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20050512

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20050512

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20080729

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20081006

RD02 Notification of acceptance of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7422

Effective date: 20081006

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20090119

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20090128

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20090310