JP2004532182A - 低濃度の塩を含有する組成物の製造方法 - Google Patents
低濃度の塩を含有する組成物の製造方法 Download PDFInfo
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- 229910021645 metal ion Inorganic materials 0.000 description 1
- 238000007069 methylation reaction Methods 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 125000001624 naphthyl group Chemical group 0.000 description 1
- 230000007935 neutral effect Effects 0.000 description 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 description 1
- 239000012038 nucleophile Substances 0.000 description 1
- 210000003463 organelle Anatomy 0.000 description 1
- 239000005416 organic matter Substances 0.000 description 1
- BPUBBGLMJRNUCC-UHFFFAOYSA-N oxygen(2-);tantalum(5+) Chemical compound [O-2].[O-2].[O-2].[O-2].[O-2].[Ta+5].[Ta+5] BPUBBGLMJRNUCC-UHFFFAOYSA-N 0.000 description 1
- RVTZCBVAJQQJTK-UHFFFAOYSA-N oxygen(2-);zirconium(4+) Chemical compound [O-2].[O-2].[Zr+4] RVTZCBVAJQQJTK-UHFFFAOYSA-N 0.000 description 1
- 125000000636 p-nitrophenyl group Chemical group [H]C1=C([H])C(=C([H])C([H])=C1*)[N+]([O-])=O 0.000 description 1
- 238000012856 packing Methods 0.000 description 1
- 230000002085 persistent effect Effects 0.000 description 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 description 1
- 239000008363 phosphate buffer Substances 0.000 description 1
- 150000003013 phosphoric acid derivatives Chemical class 0.000 description 1
- 229920002454 poly(glycidyl methacrylate) polymer Polymers 0.000 description 1
- 229920002401 polyacrylamide Polymers 0.000 description 1
- 229920000193 polymethacrylate Polymers 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 229920002451 polyvinyl alcohol Polymers 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- BDERNNFJNOPAEC-UHFFFAOYSA-N propan-1-ol Chemical compound CCCO BDERNNFJNOPAEC-UHFFFAOYSA-N 0.000 description 1
- 235000019423 pullulan Nutrition 0.000 description 1
- 230000009257 reactivity Effects 0.000 description 1
- 238000004366 reverse phase liquid chromatography Methods 0.000 description 1
- 125000006413 ring segment Chemical group 0.000 description 1
- 238000009938 salting Methods 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 229910000077 silane Inorganic materials 0.000 description 1
- 239000002002 slurry Substances 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- UIIMBOGNXHQVGW-UHFFFAOYSA-M sodium bicarbonate Substances [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 description 1
- 229910000030 sodium bicarbonate Inorganic materials 0.000 description 1
- 239000012279 sodium borohydride Substances 0.000 description 1
- 229910000033 sodium borohydride Inorganic materials 0.000 description 1
- HLBBKKJFGFRGMU-UHFFFAOYSA-M sodium formate Chemical compound [Na+].[O-]C=O HLBBKKJFGFRGMU-UHFFFAOYSA-M 0.000 description 1
- 235000019254 sodium formate Nutrition 0.000 description 1
- 239000001488 sodium phosphate Substances 0.000 description 1
- 229910000162 sodium phosphate Inorganic materials 0.000 description 1
- 229910052938 sodium sulfate Inorganic materials 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 238000002336 sorption--desorption measurement Methods 0.000 description 1
- 239000012086 standard solution Substances 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 125000000446 sulfanediyl group Chemical group *S* 0.000 description 1
- BDHFUVZGWQCTTF-UHFFFAOYSA-M sulfonate Chemical compound [O-]S(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-M 0.000 description 1
- 150000003460 sulfonic acids Chemical class 0.000 description 1
- RWSOTUBLDIXVET-UHFFFAOYSA-O sulfonium Chemical compound [SH3+] RWSOTUBLDIXVET-UHFFFAOYSA-O 0.000 description 1
- 125000004434 sulfur atom Chemical group 0.000 description 1
- 150000003467 sulfuric acid derivatives Chemical class 0.000 description 1
- 239000006228 supernatant Substances 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 230000002194 synthesizing effect Effects 0.000 description 1
- 229910001936 tantalum oxide Inorganic materials 0.000 description 1
- 150000003573 thiols Chemical class 0.000 description 1
- 229930192474 thiophene Natural products 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- JSPLKZUTYZBBKA-UHFFFAOYSA-N trioxidane Chemical compound OOO JSPLKZUTYZBBKA-UHFFFAOYSA-N 0.000 description 1
- RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical compound [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 description 1
- 238000000108 ultra-filtration Methods 0.000 description 1
- 150000003672 ureas Chemical class 0.000 description 1
- 229910001928 zirconium oxide Inorganic materials 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J41/00—Anion exchange; Use of material as anion exchangers; Treatment of material for improving the anion exchange properties
- B01J41/20—Anion exchangers for chromatographic processes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J39/00—Cation exchange; Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
- B01J39/04—Processes using organic exchangers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J39/00—Cation exchange; Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
- B01J39/26—Cation exchangers for chromatographic processes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J41/00—Anion exchange; Use of material as anion exchangers; Treatment of material for improving the anion exchange properties
- B01J41/04—Processes using organic exchangers
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Peptides Or Proteins (AREA)
- Treatment Of Water By Ion Exchange (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Seasonings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0004933A SE0004933D0 (sv) | 2000-07-17 | 2000-12-31 | A method for the manufacture of compositions containing low concentrations of salt |
| PCT/EP2001/015015 WO2002053288A2 (en) | 2000-12-31 | 2001-12-19 | A method for the manufacture of compositions containing low concentrations of salts |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004532182A true JP2004532182A (ja) | 2004-10-21 |
| JP2004532182A5 JP2004532182A5 (enExample) | 2008-11-27 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002554232A Pending JP2004532182A (ja) | 2000-12-31 | 2001-12-19 | 低濃度の塩を含有する組成物の製造方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US6852230B2 (enExample) |
| EP (1) | EP1345694B1 (enExample) |
| JP (1) | JP2004532182A (enExample) |
| AT (1) | ATE334746T1 (enExample) |
| AU (1) | AU2002235795A1 (enExample) |
| CA (1) | CA2431662A1 (enExample) |
| DE (1) | DE60121999T2 (enExample) |
| ES (1) | ES2267840T3 (enExample) |
| WO (1) | WO2002053288A2 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2016515158A (ja) * | 2013-03-15 | 2016-05-26 | ドレハー，マシュー，アール． | 結像可能な塞栓性微小球 |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4629660B2 (ja) * | 2003-03-05 | 2011-02-09 | ジーイー・ヘルスケア・バイオサイエンス・アクチボラグ | マルチモードアニオン交換リガンドの製造法 |
| SE0300612D0 (sv) * | 2003-03-05 | 2003-03-05 | Amersham Biosciences Ab | A method of preparing ligands for hydrophobic interaction chromatography |
| SE0300624D0 (sv) * | 2003-03-05 | 2003-03-05 | Amersham Biosciences Ab | A method of preparing affinity ligands |
| US7045059B2 (en) * | 2003-07-28 | 2006-05-16 | Sielc Technologies Corp | Universal bonded phase material for chromatographic separation |
| EP1718386A1 (en) * | 2004-02-27 | 2006-11-08 | GE Healthcare Bio-Sciences AB | A process for the purification of antibodies |
| SE0400501D0 (sv) * | 2004-02-27 | 2004-02-27 | Amersham Biosciences Ab | Antibody purification |
| SE529259C2 (sv) * | 2005-08-31 | 2007-06-12 | Ge Healthcare Bio Sciences Ab | Tillverkning av kromarografimatriser, en kromarografimatris, en vätskekromatografikolonn, prcess för att isolera målföreningar och användning av en kromarografimatris för vätskekromatografi |
| CA2687930C (en) * | 2007-05-25 | 2016-05-17 | Merck Patent Gesellschaft Mit Beschraenkter Haftung | Graft copolymers for cation exchange chromatography |
| US20110155668A1 (en) * | 2008-07-08 | 2011-06-30 | Ge Healthcare Bio-Sciences Ab | Separation medium for chromatography of various biomolecules |
| US20100029371A1 (en) * | 2008-08-01 | 2010-02-04 | Gennady Medvinsky | Personal Game Services Commerce System (PGSCS) |
| IN2012DN02539A (enExample) * | 2009-10-12 | 2015-08-28 | Ge Healthcare Bio Sciences Ab | |
| EP2509696B1 (en) | 2009-12-07 | 2018-07-11 | Fresenius Medical Care Holdings, Inc. | Water purification cartridge using zirconium ion-exchange sorbents |
| EP2536499A4 (en) * | 2010-02-19 | 2013-08-14 | Ge Healthcare Bio Sciences Ab | METHOD FOR PRODUCING CHROMATOGRAPHIC MEDIA |
| DE102016004432A1 (de) | 2016-04-12 | 2017-10-12 | Sartorius Stedim Biotech Gmbh | Multimodales Adsorptionsmedium mit multimodalen Liganden, Verfahren zu dessen Herstellung und dessen Verwendung |
| WO2018025809A1 (ja) | 2016-08-01 | 2018-02-08 | 株式会社カネカ | カルシプロテインパーティクルの吸着材、および吸着除去システムとその利用方法 |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1994006822A1 (en) * | 1992-09-17 | 1994-03-31 | Kem-En-Tec A/S | Method of isolating biomolecules by ion exchange |
| WO1999065607A1 (en) * | 1998-06-18 | 1999-12-23 | Amersham Pharmacia Biotech Ab | Method for separation on cation exchangers |
| WO2000069872A2 (en) * | 1999-05-14 | 2000-11-23 | Promega Corporation | pH DEPENDENT ION EXCHANGE MATRIX AND METHOD OF USE IN THE ISOLATION OF NUCLEIC ACIDS |
| JP2003514664A (ja) * | 1999-11-22 | 2003-04-22 | アメルシャム・バイオサイエンシーズ・アクチボラグ | アニオン交換吸着方法およびアニオン交換体 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3234199A (en) * | 1958-12-18 | 1966-02-08 | Allen F Reid | Ion exchange process for separating proteins |
| JPS5927830A (ja) * | 1982-08-09 | 1984-02-14 | Cosmo Co Ltd | 抗腫瘍性糖蛋白質物質 |
| US4599197A (en) * | 1982-12-22 | 1986-07-08 | Genentech, Inc. | Purification and activity assurance of precipitated heterologous proteins |
| US5652348A (en) | 1994-09-23 | 1997-07-29 | Massey University | Chromatographic resins and methods for using same |
| GB9707696D0 (en) * | 1997-04-16 | 1997-06-04 | Agner Erik | Improvements in or relating to chromatography |
| SE0002688D0 (sv) | 2000-07-17 | 2000-07-17 | Amersham Pharm Biotech Ab | Adsorption method and ligands |
-
2001
- 2001-12-19 JP JP2002554232A patent/JP2004532182A/ja active Pending
- 2001-12-19 AU AU2002235795A patent/AU2002235795A1/en not_active Abandoned
- 2001-12-19 DE DE60121999T patent/DE60121999T2/de not_active Expired - Lifetime
- 2001-12-19 WO PCT/EP2001/015015 patent/WO2002053288A2/en not_active Ceased
- 2001-12-19 EP EP01985906A patent/EP1345694B1/en not_active Expired - Lifetime
- 2001-12-19 AT AT01985906T patent/ATE334746T1/de not_active IP Right Cessation
- 2001-12-19 CA CA002431662A patent/CA2431662A1/en not_active Abandoned
- 2001-12-19 ES ES01985906T patent/ES2267840T3/es not_active Expired - Lifetime
- 2001-12-19 US US10/451,195 patent/US6852230B2/en not_active Expired - Fee Related
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1994006822A1 (en) * | 1992-09-17 | 1994-03-31 | Kem-En-Tec A/S | Method of isolating biomolecules by ion exchange |
| WO1999065607A1 (en) * | 1998-06-18 | 1999-12-23 | Amersham Pharmacia Biotech Ab | Method for separation on cation exchangers |
| JP2002518157A (ja) * | 1998-06-18 | 2002-06-25 | アメルシャム・バイオサイエンシーズ・アクチボラグ | カチオン交換体による分離方法 |
| WO2000069872A2 (en) * | 1999-05-14 | 2000-11-23 | Promega Corporation | pH DEPENDENT ION EXCHANGE MATRIX AND METHOD OF USE IN THE ISOLATION OF NUCLEIC ACIDS |
| JP2003514664A (ja) * | 1999-11-22 | 2003-04-22 | アメルシャム・バイオサイエンシーズ・アクチボラグ | アニオン交換吸着方法およびアニオン交換体 |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2016515158A (ja) * | 2013-03-15 | 2016-05-26 | ドレハー，マシュー，アール． | 結像可能な塞栓性微小球 |
| US11672876B2 (en) | 2013-03-15 | 2023-06-13 | Biocompatibles Uk Limited | Imageable embolic microsphere |
Also Published As
| Publication number | Publication date |
|---|---|
| CA2431662A1 (en) | 2002-07-11 |
| DE60121999T2 (de) | 2007-07-26 |
| EP1345694B1 (en) | 2006-08-02 |
| US20040050784A1 (en) | 2004-03-18 |
| US6852230B2 (en) | 2005-02-08 |
| DE60121999D1 (de) | 2006-09-14 |
| AU2002235795A1 (en) | 2002-07-16 |
| WO2002053288A2 (en) | 2002-07-11 |
| ES2267840T3 (es) | 2007-03-16 |
| ATE334746T1 (de) | 2006-08-15 |
| WO2002053288A3 (en) | 2002-12-12 |
| EP1345694A2 (en) | 2003-09-24 |
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