JP2004530721A5 - - Google Patents
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- Publication number
- JP2004530721A5 JP2004530721A5 JP2003508341A JP2003508341A JP2004530721A5 JP 2004530721 A5 JP2004530721 A5 JP 2004530721A5 JP 2003508341 A JP2003508341 A JP 2003508341A JP 2003508341 A JP2003508341 A JP 2003508341A JP 2004530721 A5 JP2004530721 A5 JP 2004530721A5
- Authority
- JP
- Japan
- Prior art keywords
- sustained release
- pharmaceutically active
- active ingredient
- mini
- implant
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000013268 sustained release Methods 0.000 claims 41
- 239000012730 sustained-release form Substances 0.000 claims 41
- 239000007943 implant Substances 0.000 claims 27
- 239000004480 active ingredient Substances 0.000 claims 24
- 230000036765 blood level Effects 0.000 claims 17
- 239000000203 mixture Substances 0.000 claims 14
- 239000008188 pellet Substances 0.000 claims 9
- 239000003814 drug Substances 0.000 claims 7
- -1 antidiabetics Substances 0.000 claims 6
- 229940079593 drug Drugs 0.000 claims 6
- 239000003937 drug carrier Substances 0.000 claims 6
- 238000011282 treatment Methods 0.000 claims 6
- 239000000463 material Substances 0.000 claims 5
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims 4
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims 4
- 241001465754 Metazoa Species 0.000 claims 3
- 238000000034 method Methods 0.000 claims 3
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 claims 2
- 229930006000 Sucrose Natural products 0.000 claims 2
- 229940035676 analgesics Drugs 0.000 claims 2
- 239000000730 antalgic agent Substances 0.000 claims 2
- 239000004599 antimicrobial Substances 0.000 claims 2
- 239000003096 antiparasitic agent Substances 0.000 claims 2
- 229940125687 antiparasitic agent Drugs 0.000 claims 2
- 230000004323 axial length Effects 0.000 claims 2
- 150000001720 carbohydrates Chemical class 0.000 claims 2
- 239000011248 coating agent Substances 0.000 claims 2
- 238000000576 coating method Methods 0.000 claims 2
- 201000010099 disease Diseases 0.000 claims 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 claims 2
- 150000002596 lactones Chemical class 0.000 claims 2
- 239000007788 liquid Substances 0.000 claims 2
- 239000011159 matrix material Substances 0.000 claims 2
- 229920002503 polyoxyethylene-polyoxypropylene Polymers 0.000 claims 2
- 102000004196 processed proteins & peptides Human genes 0.000 claims 2
- 108090000765 processed proteins & peptides Proteins 0.000 claims 2
- 150000003839 salts Chemical class 0.000 claims 2
- CXMXRPHRNRROMY-UHFFFAOYSA-N sebacic acid Chemical compound OC(=O)CCCCCCCCC(O)=O CXMXRPHRNRROMY-UHFFFAOYSA-N 0.000 claims 2
- 239000011780 sodium chloride Substances 0.000 claims 2
- FHHPUSMSKHSNKW-SMOYURAASA-M sodium deoxycholate Chemical compound [Na+].C([C@H]1CC2)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC([O-])=O)C)[C@@]2(C)[C@@H](O)C1 FHHPUSMSKHSNKW-SMOYURAASA-M 0.000 claims 2
- 239000005720 sucrose Substances 0.000 claims 2
- AZSNMRSAGSSBNP-UHFFFAOYSA-N 22,23-dihydroavermectin B1a Natural products C1CC(C)C(C(C)CC)OC21OC(CC=C(C)C(OC1OC(C)C(OC3OC(C)C(O)C(OC)C3)C(OC)C1)C(C)C=CC=C1C3(C(C(=O)O4)C=C(C)C(O)C3OC1)O)CC4C2 AZSNMRSAGSSBNP-UHFFFAOYSA-N 0.000 claims 1
- SPBDXSGPUHCETR-JFUDTMANSA-N 8883yp2r6d Chemical compound O1[C@@H](C)[C@H](O)[C@@H](OC)C[C@@H]1O[C@@H]1[C@@H](OC)C[C@H](O[C@@H]2C(=C/C[C@@H]3C[C@@H](C[C@@]4(O[C@@H]([C@@H](C)CC4)C(C)C)O3)OC(=O)[C@@H]3C=C(C)[C@@H](O)[C@H]4OC\C([C@@]34O)=C/C=C/[C@@H]2C)/C)O[C@H]1C.C1C[C@H](C)[C@@H]([C@@H](C)CC)O[C@@]21O[C@H](C\C=C(C)\[C@@H](O[C@@H]1O[C@@H](C)[C@H](O[C@@H]3O[C@@H](C)[C@H](O)[C@@H](OC)C3)[C@@H](OC)C1)[C@@H](C)\C=C\C=C/1[C@]3([C@H](C(=O)O4)C=C(C)[C@@H](O)[C@H]3OC\1)O)C[C@H]4C2 SPBDXSGPUHCETR-JFUDTMANSA-N 0.000 claims 1
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical class [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 claims 1
- 241000238631 Hexapoda Species 0.000 claims 1
- 208000008589 Obesity Diseases 0.000 claims 1
- 208000001132 Osteoporosis Diseases 0.000 claims 1
- 239000002202 Polyethylene glycol Substances 0.000 claims 1
- 239000004372 Polyvinyl alcohol Substances 0.000 claims 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims 1
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 claims 1
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 claims 1
- BCKXLBQYZLBQEK-KVVVOXFISA-M Sodium oleate Chemical compound [Na+].CCCCCCCC\C=C/CCCCCCCC([O-])=O BCKXLBQYZLBQEK-KVVVOXFISA-M 0.000 claims 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 claims 1
- GUGOEEXESWIERI-UHFFFAOYSA-N Terfenadine Chemical compound C1=CC(C(C)(C)C)=CC=C1C(O)CCCN1CCC(C(O)(C=2C=CC=CC=2)C=2C=CC=CC=2)CC1 GUGOEEXESWIERI-UHFFFAOYSA-N 0.000 claims 1
- 239000002253 acid Substances 0.000 claims 1
- 239000002671 adjuvant Substances 0.000 claims 1
- 150000001413 amino acids Chemical class 0.000 claims 1
- 229940124325 anabolic agent Drugs 0.000 claims 1
- 239000003263 anabolic agent Substances 0.000 claims 1
- 230000003444 anaesthetic effect Effects 0.000 claims 1
- 230000000202 analgesic effect Effects 0.000 claims 1
- 229940069428 antacid Drugs 0.000 claims 1
- 239000003159 antacid agent Substances 0.000 claims 1
- 239000003242 anti bacterial agent Substances 0.000 claims 1
- 230000001458 anti-acid effect Effects 0.000 claims 1
- 230000001165 anti-coccidial effect Effects 0.000 claims 1
- 230000001773 anti-convulsant effect Effects 0.000 claims 1
- 230000003178 anti-diabetic effect Effects 0.000 claims 1
- 230000001387 anti-histamine Effects 0.000 claims 1
- 239000002260 anti-inflammatory agent Substances 0.000 claims 1
- 229940121363 anti-inflammatory agent Drugs 0.000 claims 1
- 229940124346 antiarthritic agent Drugs 0.000 claims 1
- 239000001961 anticonvulsive agent Substances 0.000 claims 1
- 229960003965 antiepileptics Drugs 0.000 claims 1
- 229940030225 antihemorrhagics Drugs 0.000 claims 1
- 239000000739 antihistaminic agent Substances 0.000 claims 1
- 229960005475 antiinfective agent Drugs 0.000 claims 1
- 239000003904 antiprotozoal agent Substances 0.000 claims 1
- 239000003435 antirheumatic agent Substances 0.000 claims 1
- 239000003699 antiulcer agent Substances 0.000 claims 1
- 239000003443 antiviral agent Substances 0.000 claims 1
- 230000003542 behavioural effect Effects 0.000 claims 1
- 239000000560 biocompatible material Substances 0.000 claims 1
- 229960000074 biopharmaceutical Drugs 0.000 claims 1
- 239000008280 blood Substances 0.000 claims 1
- 210000004369 blood Anatomy 0.000 claims 1
- 239000003633 blood substitute Substances 0.000 claims 1
- 230000036760 body temperature Effects 0.000 claims 1
- 229940124630 bronchodilator Drugs 0.000 claims 1
- 239000000168 bronchodilator agent Substances 0.000 claims 1
- 239000003560 cancer drug Substances 0.000 claims 1
- 239000003576 central nervous system agent Substances 0.000 claims 1
- 239000008199 coating composition Substances 0.000 claims 1
- 229940124558 contraceptive agent Drugs 0.000 claims 1
- 239000003433 contraceptive agent Substances 0.000 claims 1
- 239000002872 contrast media Substances 0.000 claims 1
- 235000014113 dietary fatty acids Nutrition 0.000 claims 1
- 235000015872 dietary supplement Nutrition 0.000 claims 1
- KPUWHANPEXNPJT-UHFFFAOYSA-N disiloxane Chemical class [SiH3]O[SiH3] KPUWHANPEXNPJT-UHFFFAOYSA-N 0.000 claims 1
- 239000002934 diuretic Substances 0.000 claims 1
- 229940030606 diuretics Drugs 0.000 claims 1
- 239000005038 ethylene vinyl acetate Substances 0.000 claims 1
- 239000003172 expectorant agent Substances 0.000 claims 1
- 230000003419 expectorant effect Effects 0.000 claims 1
- 229940066493 expectorants Drugs 0.000 claims 1
- 239000003889 eye drop Substances 0.000 claims 1
- 229940012356 eye drops Drugs 0.000 claims 1
- 239000000194 fatty acid Substances 0.000 claims 1
- 229930195729 fatty acid Natural products 0.000 claims 1
- 150000004665 fatty acids Chemical class 0.000 claims 1
- 229910021485 fumed silica Inorganic materials 0.000 claims 1
- 239000000122 growth hormone Substances 0.000 claims 1
- 239000007952 growth promoter Substances 0.000 claims 1
- 239000003630 growth substance Substances 0.000 claims 1
- 230000003394 haemopoietic effect Effects 0.000 claims 1
- 239000002874 hemostatic agent Substances 0.000 claims 1
- 230000002439 hemostatic effect Effects 0.000 claims 1
- 239000005556 hormone Substances 0.000 claims 1
- 229940088597 hormone Drugs 0.000 claims 1
- 238000002657 hormone replacement therapy Methods 0.000 claims 1
- 229960001438 immunostimulant agent Drugs 0.000 claims 1
- 239000003022 immunostimulating agent Substances 0.000 claims 1
- 230000003308 immunostimulating effect Effects 0.000 claims 1
- 239000007924 injection Substances 0.000 claims 1
- 238000002347 injection Methods 0.000 claims 1
- 229910052500 inorganic mineral Inorganic materials 0.000 claims 1
- 229910017053 inorganic salt Inorganic materials 0.000 claims 1
- 238000007918 intramuscular administration Methods 0.000 claims 1
- 229960002418 ivermectin Drugs 0.000 claims 1
- 230000003340 mental effect Effects 0.000 claims 1
- 239000011707 mineral Substances 0.000 claims 1
- 229940035363 muscle relaxants Drugs 0.000 claims 1
- 239000003158 myorelaxant agent Substances 0.000 claims 1
- 229930014626 natural product Natural products 0.000 claims 1
- 235000015097 nutrients Nutrition 0.000 claims 1
- 235000020824 obesity Nutrition 0.000 claims 1
- 230000016087 ovulation Effects 0.000 claims 1
- 239000007800 oxidant agent Substances 0.000 claims 1
- 229920001200 poly(ethylene-vinyl acetate) Polymers 0.000 claims 1
- 229920000728 polyester Polymers 0.000 claims 1
- 229920001223 polyethylene glycol Polymers 0.000 claims 1
- 229920000223 polyglycerol Polymers 0.000 claims 1
- 229920000642 polymer Polymers 0.000 claims 1
- 229920001184 polypeptide Polymers 0.000 claims 1
- 229920001296 polysiloxane Polymers 0.000 claims 1
- 229920002451 polyvinyl alcohol Polymers 0.000 claims 1
- 238000002360 preparation method Methods 0.000 claims 1
- 239000000047 product Substances 0.000 claims 1
- 238000011321 prophylaxis Methods 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 239000012763 reinforcing filler Substances 0.000 claims 1
- 230000000241 respiratory effect Effects 0.000 claims 1
- 229910052710 silicon Inorganic materials 0.000 claims 1
- 239000010703 silicon Substances 0.000 claims 1
- 239000002210 silicon-based material Substances 0.000 claims 1
- 235000019333 sodium laurylsulphate Nutrition 0.000 claims 1
- 239000007787 solid Substances 0.000 claims 1
- 238000007920 subcutaneous administration Methods 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
- 229920001059 synthetic polymer Polymers 0.000 claims 1
- 239000003826 tablet Substances 0.000 claims 1
- 230000001225 therapeutic effect Effects 0.000 claims 1
- 230000002485 urinary effect Effects 0.000 claims 1
- 229960005486 vaccine Drugs 0.000 claims 1
- 230000002792 vascular Effects 0.000 claims 1
- 239000011782 vitamin Substances 0.000 claims 1
- 229930003231 vitamin Natural products 0.000 claims 1
- 235000013343 vitamin Nutrition 0.000 claims 1
- 229940088594 vitamin Drugs 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AUPR6025 | 2001-06-29 | ||
| AUPR6025A AUPR602501A0 (en) | 2001-06-29 | 2001-06-29 | Sustained release pharmaceutical composition |
| PCT/AU2002/000865 WO2003002102A1 (en) | 2001-06-29 | 2002-07-01 | Sustained release pharmaceutical composition |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2004530721A JP2004530721A (ja) | 2004-10-07 |
| JP2004530721A5 true JP2004530721A5 (https=) | 2005-12-22 |
| JP4800570B2 JP4800570B2 (ja) | 2011-10-26 |
Family
ID=3829991
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003508341A Expired - Fee Related JP4800570B2 (ja) | 2001-06-29 | 2002-07-01 | 徐放性医薬組成物 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20040241204A1 (https=) |
| EP (1) | EP1411904A4 (https=) |
| JP (1) | JP4800570B2 (https=) |
| CN (1) | CN1731988A (https=) |
| AU (2) | AUPR602501A0 (https=) |
| BR (1) | BR0210631A (https=) |
| CA (1) | CA2452030A1 (https=) |
| CO (1) | CO5540373A2 (https=) |
| NZ (1) | NZ529859A (https=) |
| WO (1) | WO2003002102A1 (https=) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050129728A1 (en) * | 2001-09-11 | 2005-06-16 | Martinod Serge R. | Sustained release pharmaceutical composition |
| CN1638747A (zh) * | 2002-01-24 | 2005-07-13 | 斯玛特药物系统公司 | 持续释放药物组合物 |
| CN101683317A (zh) * | 2004-05-31 | 2010-03-31 | 斯玛特药物系统公司 | 缓释组合物 |
| JP2008502605A (ja) * | 2004-06-16 | 2008-01-31 | スマート ドラッグ システムズ インコーポレイティド | 徐放性ワクチン組成物 |
| AU2005253646B2 (en) * | 2004-06-16 | 2011-09-15 | Virbac Corporation | Sustained release vaccine composition |
| PT1781264E (pt) | 2004-08-04 | 2013-10-16 | Evonik Corp | Métodos para o fabrico de dispositivis de administração e dispositivos para a mesma |
| EP1859788A1 (en) * | 2006-05-24 | 2007-11-28 | Abbott GmbH & Co. KG | Production of enveloped pharmaceutical dosage forms |
| NZ552290A (en) * | 2006-12-21 | 2009-05-31 | Bomac Research Ltd | Tablet fomulation |
| BRPI0705822A2 (pt) * | 2007-10-25 | 2009-06-23 | Schering Plough Saude Animal Ltda | formulação injetável com ação prolongada e uso de um agente semi-sintético derivado do grupo das avermectinas, em combinação com um polìmero biodegradável |
| ES2718612T3 (es) | 2007-12-20 | 2019-07-03 | Evonik Corp | Procedimiento para preparar micropartículas que tienen un bajo volumen de disolvente residual |
| EP2352544A4 (en) * | 2008-11-07 | 2013-12-25 | Combinent Biomedical Systems Inc | DEVICES AND METHOD FOR THE TREATMENT AND / OR PREVENTION OF DISEASES |
| CA2755753A1 (en) | 2009-03-17 | 2010-09-23 | Intervet International B.V. | Macrocyclic lactone drug delivery system |
| KR101957625B1 (ko) * | 2010-06-01 | 2019-03-12 | 백스터 인터내셔널 인코포레이티드 | 건조 및 안정한 지혈 조성물의 제조 방법 |
| PT2598151T (pt) | 2010-07-30 | 2019-04-15 | Ceva Sante Animale Sa | Composições para o tratamento da infestação por vermes do coração |
| JP5696279B2 (ja) * | 2010-12-01 | 2015-04-08 | 学校法人自治医科大学 | 長期徐放型薬剤硬膜外腔留置システム |
| BR112014013371B1 (pt) | 2011-12-02 | 2020-04-07 | Merial Ltd | formulações de moxidectina injetável de ação prolongada e novas formas de cristal de moxidectina |
| US20130190839A1 (en) * | 2012-01-20 | 2013-07-25 | Jane Rapsey | Drug delivery using a sacrificial host |
| WO2014160026A2 (en) * | 2013-03-14 | 2014-10-02 | Endo Pharmaceuticals Solutions Inc. | Implantable drug delivery compositions comprising sugar-based sorption enhancers and methods of treatment thereof |
| AU2013209343B1 (en) * | 2013-05-14 | 2014-04-24 | Activesignal Holding Limited | Device for the Treatment of Bone Conditions |
| AR101476A1 (es) | 2014-08-07 | 2016-12-21 | Acerta Pharma Bv | Métodos para tratar cánceres, enfermedades inmunes y autoinmunes, y enfermedades inflamatorias en base a la tasa de ocupación de la tirosin quinasa de bruton (btk) y a la tasa de resíntesis de la tirosin quinasa de bruton (btk) |
| ITUB20153652A1 (it) | 2015-09-16 | 2017-03-16 | Fatro Spa | Microsfere contenenti lattoni macrociclici antielminitici |
| CN118680883A (zh) * | 2018-06-25 | 2024-09-24 | 瑞艾克斯制药公司 | 用作植入物的可负载多孔结构 |
| US20220152044A1 (en) * | 2019-03-14 | 2022-05-19 | Palmaya Pty Ltd | Treatment of inflammatory diseases of the central nervous system |
| CN110559431B (zh) * | 2019-10-11 | 2023-02-28 | 南京农业大学 | 一种巨型艾美耳球虫纳米亚单位疫苗及其制备方法和应用 |
| EP4477215A3 (en) | 2020-12-08 | 2025-02-19 | Ruminant Biotech Corp Limited | Improvements to devices and methods for delivery of substances to animals |
| US20240238226A1 (en) * | 2021-03-09 | 2024-07-18 | Adnan I. Qureshi | Implantable sustained release device and a method of use thereof |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3279996A (en) * | 1962-08-28 | 1966-10-18 | Jr David M Long | Polysiloxane carrier for controlled release of drugs and other agents |
| US4053580A (en) * | 1975-01-01 | 1977-10-11 | G. D. Searle & Co. | Microsealed pharmaceutical delivery device |
| US4331652A (en) * | 1979-09-12 | 1982-05-25 | Eli Lilly And Company | Controlled release parasitic formulations and method |
| US4723958A (en) * | 1986-05-23 | 1988-02-09 | Merck & Co., Inc. | Pulsatile drug delivery system |
| US5028430A (en) * | 1987-05-08 | 1991-07-02 | Syntex (U.S.A.) Inc. | Delivery systems for the controlled administration of LHRH analogs |
| DK0463061T3 (da) * | 1989-03-17 | 1993-07-12 | Pitman Moore Inc | Controlled-release tilførselsindretning til afgivelse af makromolekylære proteiner |
| FI916066A0 (fi) * | 1989-06-21 | 1991-12-20 | Univ Brown Res Found | Neurologiskt vaordsystem. |
| FR2653338B1 (fr) * | 1989-10-23 | 1994-06-10 | Dow Corning Sa | Formulation pour des pansements a liberation prolongee de medicament et son utilisation. |
| AU660290B2 (en) * | 1990-08-09 | 1995-06-22 | Endocon, Inc. | Multiple drug delivery system |
| NZ239370A (en) * | 1990-08-22 | 1994-04-27 | Merck & Co Inc | Bioerodible implantable controlled release dosage form comprising a poly(ortho ester) or a polyacetal with an active agent incorporated into the chain backbone |
| US5211951A (en) * | 1991-07-24 | 1993-05-18 | Merck & Co., Inc. | Process for the manufacture of bioerodible poly (orthoester)s and polyacetals |
| JPH06321803A (ja) * | 1993-05-17 | 1994-11-22 | Kirin Brewery Co Ltd | 水溶性ペプチドホルモンの徐放性製剤 |
| JP3720386B2 (ja) * | 1993-12-27 | 2005-11-24 | 住友製薬株式会社 | 薬物放出制御製剤 |
| FR2745180B1 (fr) * | 1996-02-23 | 1998-05-07 | Dow Corning Sa | Procede de fabrication de dispositifs a liberation controlee |
| BR9812385A (pt) * | 1997-09-23 | 2000-09-12 | Pfizer | Formulações parasiticidas |
| AUPP279698A0 (en) * | 1998-04-03 | 1998-04-30 | Sunscape Developments Limited | Sustained release formulation |
| AU752225B2 (en) * | 1998-07-17 | 2002-09-12 | Pacira Pharmaceuticals, Inc. | Biodegradable compositions for the controlled release of encapsulated substances |
| GB9816132D0 (en) * | 1998-07-24 | 1998-09-23 | Norbrook Lab Ltd | Non-aqueous anthelmintic composition |
| AU5532699A (en) * | 1998-09-05 | 2000-03-27 | Seung Jin Lee | Biodegradable particulate polymeric preparation and process for producing thereof |
| US6645192B2 (en) * | 1998-09-30 | 2003-11-11 | Ivy Animal Health, Inc. | Pellet implant system for immediate and delayed release of antiparasitic drug |
| WO2000018374A1 (en) * | 1998-10-01 | 2000-04-06 | Elan Pharma International, Ltd. | Controlled release nanoparticulate compositions |
| CN1378445B (zh) * | 1999-08-06 | 2013-02-06 | 得克萨斯系统大学评议会 | 药物释放生物可降解纤维植入物 |
| TW524696B (en) * | 1999-11-10 | 2003-03-21 | Sumitomo Pharma | Sustained-release drug formulations |
| AU1556000A (en) * | 1999-11-22 | 2001-06-04 | Akzo Nobel N.V. | Composition allowing predefined and controlled release of active ingredient, preparation thereof and use |
| US20020131988A1 (en) * | 1999-12-16 | 2002-09-19 | Foster Todd P. | Pharmaceutical implant containing immediate-release and sustained-release components and method of administration |
| US6998137B2 (en) * | 2000-04-07 | 2006-02-14 | Macromed, Inc. | Proteins deposited onto sparingly soluble biocompatible particles for controlled protein release into a biological environment from a polymer matrix |
-
2001
- 2001-06-29 AU AUPR6025A patent/AUPR602501A0/en not_active Abandoned
-
2002
- 2002-07-01 AU AU2002344685A patent/AU2002344685B2/en not_active Ceased
- 2002-07-01 BR BR0210631-0A patent/BR0210631A/pt not_active IP Right Cessation
- 2002-07-01 WO PCT/AU2002/000865 patent/WO2003002102A1/en not_active Ceased
- 2002-07-01 CA CA002452030A patent/CA2452030A1/en not_active Abandoned
- 2002-07-01 US US10/482,336 patent/US20040241204A1/en not_active Abandoned
- 2002-07-01 NZ NZ529859A patent/NZ529859A/en not_active IP Right Cessation
- 2002-07-01 JP JP2003508341A patent/JP4800570B2/ja not_active Expired - Fee Related
- 2002-07-01 EP EP02742515A patent/EP1411904A4/en not_active Ceased
- 2002-07-01 CN CNA028131525A patent/CN1731988A/zh active Pending
-
2003
- 2003-12-23 CO CO03112102A patent/CO5540373A2/es unknown
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