JP2004526499A5 - - Google Patents
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- JP2004526499A5 JP2004526499A5 JP2002572908A JP2002572908A JP2004526499A5 JP 2004526499 A5 JP2004526499 A5 JP 2004526499A5 JP 2002572908 A JP2002572908 A JP 2002572908A JP 2002572908 A JP2002572908 A JP 2002572908A JP 2004526499 A5 JP2004526499 A5 JP 2004526499A5
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- Prior art keywords
- stent
- layer
- drug
- polymer
- agents
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- 229940079593 drug Drugs 0.000 claims 34
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- FJWGYAHXMCUOOM-QHOUIDNNSA-N [(2s,3r,4s,5r,6r)-2-[(2r,3r,4s,5r,6s)-4,5-dinitrooxy-2-(nitrooxymethyl)-6-[(2r,3r,4s,5r,6s)-4,5,6-trinitrooxy-2-(nitrooxymethyl)oxan-3-yl]oxyoxan-3-yl]oxy-3,5-dinitrooxy-6-(nitrooxymethyl)oxan-4-yl] nitrate Chemical compound O([C@@H]1O[C@@H]([C@H]([C@H](O[N+]([O-])=O)[C@H]1O[N+]([O-])=O)O[C@H]1[C@@H]([C@@H](O[N+]([O-])=O)[C@H](O[N+]([O-])=O)[C@@H](CO[N+]([O-])=O)O1)O[N+]([O-])=O)CO[N+](=O)[O-])[C@@H]1[C@@H](CO[N+]([O-])=O)O[C@@H](O[N+]([O-])=O)[C@H](O[N+]([O-])=O)[C@H]1O[N+]([O-])=O FJWGYAHXMCUOOM-QHOUIDNNSA-N 0.000 claims 5
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- PUDHBTGHUJUUFI-SCTWWAJVSA-N (4r,7s,10s,13r,16s,19r)-10-(4-aminobutyl)-n-[(2s,3r)-1-amino-3-hydroxy-1-oxobutan-2-yl]-19-[[(2r)-2-amino-3-naphthalen-2-ylpropanoyl]amino]-16-[(4-hydroxyphenyl)methyl]-13-(1h-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-7-propan-2-yl-1,2-dithia-5,8,11,14,17-p Chemical compound C([C@H]1C(=O)N[C@H](CC=2C3=CC=CC=C3NC=2)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(N[C@@H](CSSC[C@@H](C(=O)N1)NC(=O)[C@H](N)CC=1C=C2C=CC=CC2=CC=1)C(=O)N[C@@H]([C@@H](C)O)C(N)=O)=O)C(C)C)C1=CC=C(O)C=C1 PUDHBTGHUJUUFI-SCTWWAJVSA-N 0.000 claims 2
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- ZFXYFBGIUFBOJW-UHFFFAOYSA-N theophylline Chemical compound O=C1N(C)C(=O)N(C)C2=C1NC=N2 ZFXYFBGIUFBOJW-UHFFFAOYSA-N 0.000 claims 2
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- GQGRDYWMOPRROR-ZIFKCHSBSA-N (e)-7-[(1r,2r,3s,5s)-3-hydroxy-5-[(4-phenylphenyl)methoxy]-2-piperidin-1-ylcyclopentyl]hept-4-enoic acid Chemical compound O([C@H]1C[C@@H]([C@@H]([C@H]1CC\C=C\CCC(O)=O)N1CCCCC1)O)CC(C=C1)=CC=C1C1=CC=CC=C1 GQGRDYWMOPRROR-ZIFKCHSBSA-N 0.000 claims 1
- KUBDPQJOLOUJRM-UHFFFAOYSA-N 2-(chloromethyl)oxirane;4-[2-(4-hydroxyphenyl)propan-2-yl]phenol Chemical compound ClCC1CO1.C=1C=C(O)C=CC=1C(C)(C)C1=CC=C(O)C=C1 KUBDPQJOLOUJRM-UHFFFAOYSA-N 0.000 claims 1
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- SUZLHDUTVMZSEV-UHFFFAOYSA-N Deoxycoleonol Natural products C12C(=O)CC(C)(C=C)OC2(C)C(OC(=O)C)C(O)C2C1(C)C(O)CCC2(C)C SUZLHDUTVMZSEV-UHFFFAOYSA-N 0.000 claims 1
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| US27608901P | 2001-03-16 | 2001-03-16 | |
| PCT/US2002/008039 WO2002074194A2 (en) | 2001-03-16 | 2002-03-18 | Stent with medicated multi-layer hydrid polymer coating |
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| JP2009092512A Pending JP2009160427A (ja) | 2001-03-16 | 2009-04-06 | 複数層ポリマーコーティングを有する薬物添加ステント |
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| JP (2) | JP2004526499A (https=) |
| AU (1) | AU2002252372A1 (https=) |
| WO (1) | WO2002074194A2 (https=) |
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| US6908624B2 (en) * | 1999-12-23 | 2005-06-21 | Advanced Cardiovascular Systems, Inc. | Coating for implantable devices and a method of forming the same |
| US7771468B2 (en) * | 2001-03-16 | 2010-08-10 | Angiotech Biocoatings Corp. | Medicated stent having multi-layer polymer coating |
| KR100455343B1 (ko) * | 2001-08-29 | 2004-11-12 | 학교법인 인하학원 | 약물 방출 스텐트용 코팅 조성물 및 이를 사용하여 제조된약물 방출 스텐트 |
| US8003179B2 (en) * | 2002-06-20 | 2011-08-23 | Alcan Packaging Flexible France | Films having a desiccant material incorporated therein and methods of use and manufacture |
| DE60316720T2 (de) | 2002-10-22 | 2008-07-17 | Medtronic Vascular, Inc., Santa Rosa | Stent mit intermittierender beschichtung |
| SI2656854T1 (sl) * | 2003-02-04 | 2015-09-30 | Cornell Research Foundation, Inc. | Uporabe aromatsko-kationskega peptida |
| US20050118344A1 (en) | 2003-12-01 | 2005-06-02 | Pacetti Stephen D. | Temperature controlled crimping |
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| US20050064005A1 (en) * | 2003-08-13 | 2005-03-24 | Dinh Thomas Q. | Active agent delivery systems including a miscible polymer blend, medical devices, and methods |
| CA2535346A1 (en) * | 2003-08-13 | 2005-03-03 | Medtronic, Inc. | Active agent delivery systems, including a single layer of a miscible polymer blend, medical devices, and methods |
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| CA2996768C (en) | 2006-04-26 | 2020-12-08 | Micell Technologies, Inc. | Coatings containing multiple drugs |
| CN101678388B (zh) | 2006-10-23 | 2013-12-11 | 米歇尔技术公司 | 用于在涂覆过程中为基底充电的保持器 |
| EP2101779A1 (en) * | 2006-12-13 | 2009-09-23 | Angiotech Pharmaceuticals, Inc. | Medical implants with a combination of compounds |
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| US11426494B2 (en) | 2007-01-08 | 2022-08-30 | MT Acquisition Holdings LLC | Stents having biodegradable layers |
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| EP1990356A1 (en) * | 2007-05-10 | 2008-11-12 | Abbott Laboratories Vascular Enterprises Limited | Co-polymer of a modifed polyamide and a polycarbonate |
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| JP5597625B2 (ja) * | 2009-03-02 | 2014-10-01 | 株式会社日本ステントテクノロジー | 薬剤溶出性ステント |
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| CA2797110C (en) | 2010-04-22 | 2020-07-21 | Micell Technologies, Inc. | Stents and other devices having extracellular matrix coating |
| EP2593039B1 (en) | 2010-07-16 | 2022-11-30 | Micell Technologies, Inc. | Drug delivery medical device |
| CN102166377A (zh) * | 2011-01-05 | 2011-08-31 | 北京泰杰伟业科技有限公司 | 医用导管润滑亲水涂层的组合物、制备方法与使用方法 |
| US10464100B2 (en) | 2011-05-31 | 2019-11-05 | Micell Technologies, Inc. | System and process for formation of a time-released, drug-eluting transferable coating |
| US10117972B2 (en) | 2011-07-15 | 2018-11-06 | Micell Technologies, Inc. | Drug delivery medical device |
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| AU2014248508B2 (en) | 2013-03-12 | 2018-11-08 | Micell Technologies, Inc. | Bioabsorbable biomedical implants |
| US9545301B2 (en) | 2013-03-15 | 2017-01-17 | Covidien Lp | Coated medical devices and methods of making and using same |
| US9320592B2 (en) * | 2013-03-15 | 2016-04-26 | Covidien Lp | Coated medical devices and methods of making and using same |
| WO2014186532A1 (en) | 2013-05-15 | 2014-11-20 | Micell Technologies, Inc. | Bioabsorbable biomedical implants |
| US9668890B2 (en) | 2013-11-22 | 2017-06-06 | Covidien Lp | Anti-thrombogenic medical devices and methods |
| CN109966548A (zh) * | 2019-03-05 | 2019-07-05 | 太阳雨林（厦门）生物医药有限公司 | 一种双层高分子材料复合血管 |
| CN116808316B (zh) * | 2023-06-29 | 2024-07-09 | 征鸿诺瓦医疗科技(深圳)有限公司 | 药物洗脱支架表面载药和抗凝血复合涂层的制备方法及心脏支架 |
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| AU716005B2 (en) * | 1995-06-07 | 2000-02-17 | Cook Medical Technologies Llc | Implantable medical device |
| WO1998008884A1 (en) * | 1996-08-26 | 1998-03-05 | Tyndale Plains-Hunter, Ltd. | Hydrophilic and hydrophobic polyether polyurethanes and uses therefor |
| WO1998057671A2 (en) * | 1997-06-18 | 1998-12-23 | Boston Scientific Corporation | Polycarbonate-polyurethane dispersions for thrombo-resistant coatings |
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| US6251136B1 (en) * | 1999-12-08 | 2001-06-26 | Advanced Cardiovascular Systems, Inc. | Method of layering a three-coated stent using pharmacological and polymeric agents |
| US6379382B1 (en) * | 2000-03-13 | 2002-04-30 | Jun Yang | Stent having cover with drug delivery capability |
-
2002
- 2002-03-18 WO PCT/US2002/008039 patent/WO2002074194A2/en not_active Ceased
- 2002-03-18 AU AU2002252372A patent/AU2002252372A1/en not_active Abandoned
- 2002-03-18 EP EP02721439A patent/EP1399094A4/en not_active Withdrawn
- 2002-03-18 JP JP2002572908A patent/JP2004526499A/ja active Pending
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2009
- 2009-04-06 JP JP2009092512A patent/JP2009160427A/ja active Pending
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