JP2004525988A - サイモシンβ４を用いる表皮水疱症（ＥｐｉｄｅｒｍｏｌｙｓｉｓＢｕｌｌｏｓａ）の治療 - Google Patents
サイモシンβ４を用いる表皮水疱症（ＥｐｉｄｅｒｍｏｌｙｓｉｓＢｕｌｌｏｓａ）の治療 Download PDFInfo
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- epidermolysis bullosa
- polypeptide
- skin
- thymosin
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- VBEQCZHXXJYVRD-GACYYNSASA-N uroanthelone Chemical compound C([C@@H](C(=O)N[C@H](C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CS)C(=O)N[C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O)C(C)C)[C@@H](C)O)NC(=O)[C@H](CO)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CC=1NC=NC=1)NC(=O)[C@H](CCSC)NC(=O)[C@H](CS)NC(=O)[C@@H](NC(=O)CNC(=O)CNC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CS)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](CS)NC(=O)CNC(=O)[C@H]1N(CCC1)C(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC(N)=O)C(C)C)[C@@H](C)CC)C1=CC=C(O)C=C1 VBEQCZHXXJYVRD-GACYYNSASA-N 0.000 description 1
- 239000004474 valine Substances 0.000 description 1
- 210000005166 vasculature Anatomy 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/2292—Thymosin; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Dermatology (AREA)
- Zoology (AREA)
- Endocrinology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US29132601P | 2001-05-17 | 2001-05-17 | |
| PCT/US2002/015394 WO2002091969A1 (en) | 2001-05-17 | 2002-05-16 | Treating epidermlyosis bullosa with thymosin beta 4 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004525988A true JP2004525988A (ja) | 2004-08-26 |
| JP2004525988A5 JP2004525988A5 (enExample) | 2005-12-22 |
Family
ID=23119854
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002588889A Pending JP2004525988A (ja) | 2001-05-17 | 2002-05-16 | サイモシンβ４を用いる表皮水疱症（ＥｐｉｄｅｒｍｏｌｙｓｉｓＢｕｌｌｏｓａ）の治療 |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP1404268A4 (enExample) |
| JP (1) | JP2004525988A (enExample) |
| CN (1) | CN1241636C (enExample) |
| AU (1) | AU2002309842B2 (enExample) |
| CA (1) | CA2446072A1 (enExample) |
| MX (1) | MXPA03010446A (enExample) |
| WO (1) | WO2002091969A1 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2011514383A (ja) * | 2008-03-17 | 2011-05-06 | リジェナークス・バイオファーマスーティカルズ・インコーポレイテッド | 改良されたベータチモシンフラグメント |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007521336A (ja) * | 2003-12-22 | 2007-08-02 | リジェナークス・バイオファーマシューティカルズ・インコーポレイテッド | 反応性化学物質、生物学的物質、もしくは毒素に対する、生物学的もしくは免疫学的応答を、処理もしくは防止する方法 |
| US8632827B2 (en) * | 2011-12-13 | 2014-01-21 | Avon Products, Inc | Modulation of thymosin beta-4 in skin |
| WO2014093053A1 (en) * | 2012-12-11 | 2014-06-19 | Avon Products, Inc. | Modulation of thymosin beta-4 in skin |
| CN104324279A (zh) * | 2014-11-19 | 2015-02-04 | 吕玲 | 一种治疗皮肤发育不良的中药药剂及制备方法 |
| WO2017214910A1 (zh) * | 2016-06-15 | 2017-12-21 | 石庆学 | 特异促进Tβ4基因高表达的慢病毒表达载体及其应用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6087341A (en) * | 1998-02-12 | 2000-07-11 | The Board Of Trustees Of The Leland Standford Junior University | Introduction of nucleic acid into skin cells by topical application |
| EP2311485A1 (en) * | 1998-07-30 | 2011-04-20 | The Government of the United States of America, as represented by the Secretary of Health and Human Services | Thymosin beta 4 promotes wound repair |
-
2002
- 2002-05-16 CN CNB028100956A patent/CN1241636C/zh not_active Expired - Fee Related
- 2002-05-16 WO PCT/US2002/015394 patent/WO2002091969A1/en not_active Ceased
- 2002-05-16 JP JP2002588889A patent/JP2004525988A/ja active Pending
- 2002-05-16 EP EP02736866A patent/EP1404268A4/en not_active Withdrawn
- 2002-05-16 AU AU2002309842A patent/AU2002309842B2/en not_active Ceased
- 2002-05-16 CA CA002446072A patent/CA2446072A1/en not_active Abandoned
- 2002-05-16 MX MXPA03010446A patent/MXPA03010446A/es not_active Application Discontinuation
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2011514383A (ja) * | 2008-03-17 | 2011-05-06 | リジェナークス・バイオファーマスーティカルズ・インコーポレイテッド | 改良されたベータチモシンフラグメント |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1241636C (zh) | 2006-02-15 |
| CA2446072A1 (en) | 2002-11-21 |
| CN1511017A (zh) | 2004-07-07 |
| EP1404268A4 (en) | 2006-03-01 |
| MXPA03010446A (es) | 2004-12-06 |
| WO2002091969A1 (en) | 2002-11-21 |
| EP1404268A1 (en) | 2004-04-07 |
| AU2002309842B2 (en) | 2006-02-02 |
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