CN1241636C - 用胸腺素β4治疗大疱性表皮松解症 - Google Patents

用胸腺素β4治疗大疱性表皮松解症 Download PDF

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Publication number
CN1241636C
CN1241636C CNB028100956A CN02810095A CN1241636C CN 1241636 C CN1241636 C CN 1241636C CN B028100956 A CNB028100956 A CN B028100956A CN 02810095 A CN02810095 A CN 02810095A CN 1241636 C CN1241636 C CN 1241636C
Authority
CN
China
Prior art keywords
composition
polypeptide
skin
beta
thymosin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CNB028100956A
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English (en)
Chinese (zh)
Other versions
CN1511017A (zh
Inventor
阿兰·L·戈尔茨坦
小杰克·芬克尔斯坦
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
RegeneRx Biopharmaceuticals Inc
Original Assignee
RegeneRx Biopharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by RegeneRx Biopharmaceuticals Inc filed Critical RegeneRx Biopharmaceuticals Inc
Publication of CN1511017A publication Critical patent/CN1511017A/zh
Application granted granted Critical
Publication of CN1241636C publication Critical patent/CN1241636C/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/2292—Thymosin; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
CNB028100956A 2001-05-17 2002-05-16 用胸腺素β4治疗大疱性表皮松解症 Expired - Fee Related CN1241636C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US29132601P 2001-05-17 2001-05-17
US60/291,326 2001-05-17

Publications (2)

Publication Number Publication Date
CN1511017A CN1511017A (zh) 2004-07-07
CN1241636C true CN1241636C (zh) 2006-02-15

Family

ID=23119854

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB028100956A Expired - Fee Related CN1241636C (zh) 2001-05-17 2002-05-16 用胸腺素β4治疗大疱性表皮松解症

Country Status (7)

Country Link
EP (1) EP1404268A4 (enExample)
JP (1) JP2004525988A (enExample)
CN (1) CN1241636C (enExample)
AU (1) AU2002309842B2 (enExample)
CA (1) CA2446072A1 (enExample)
MX (1) MXPA03010446A (enExample)
WO (1) WO2002091969A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1897965A (zh) * 2003-12-22 2007-01-17 雷金纳克斯生物制药公司 反应性的化学剂、生物剂或毒素引起的生物反应或免疫反应的治疗方法或预防方法
EP2260106A4 (en) * 2008-03-17 2011-04-20 Regenerx Biopharmaceuticals IMPROVED BETATHYMOSINFRAGMENTS
US8632827B2 (en) * 2011-12-13 2014-01-21 Avon Products, Inc Modulation of thymosin beta-4 in skin
WO2014093053A1 (en) * 2012-12-11 2014-06-19 Avon Products, Inc. Modulation of thymosin beta-4 in skin
CN104324279A (zh) * 2014-11-19 2015-02-04 吕玲 一种治疗皮肤发育不良的中药药剂及制备方法
WO2017214910A1 (zh) * 2016-06-15 2017-12-21 石庆学 特异促进Tβ4基因高表达的慢病毒表达载体及其应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6087341A (en) * 1998-02-12 2000-07-11 The Board Of Trustees Of The Leland Standford Junior University Introduction of nucleic acid into skin cells by topical application
EP1100529B2 (en) * 1998-07-30 2010-08-25 The Government of the United States of America, as repres. by the Secretary of Health and Human Services, Nat. Inst. of Health Thymosin beta 4 promotes wound repair

Also Published As

Publication number Publication date
MXPA03010446A (es) 2004-12-06
WO2002091969A1 (en) 2002-11-21
CN1511017A (zh) 2004-07-07
EP1404268A1 (en) 2004-04-07
EP1404268A4 (en) 2006-03-01
CA2446072A1 (en) 2002-11-21
JP2004525988A (ja) 2004-08-26
AU2002309842B2 (en) 2006-02-02

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Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
C17 Cessation of patent right
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20060215

Termination date: 20120516