JP2004525140A - ガンの治療方法及び該治療方法に使用する組成物 - Google Patents

ガンの治療方法及び該治療方法に使用する組成物 Download PDF

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JP2004525140A
JP2004525140A JP2002574969A JP2002574969A JP2004525140A JP 2004525140 A JP2004525140 A JP 2004525140A JP 2002574969 A JP2002574969 A JP 2002574969A JP 2002574969 A JP2002574969 A JP 2002574969A JP 2004525140 A JP2004525140 A JP 2004525140A
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alkenyl
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JP2004525140A5 (https=
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デビッド ローレンス モーリス
モハメッド ホセイン ポールオラミ
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ユニサーチ リミテッド
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Priority claimed from CA 2342472 external-priority patent/CA2342472A1/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/41841,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • A61K31/53771,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/541Non-condensed thiazines containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
JP2002574969A 2001-03-26 2002-03-20 ガンの治療方法及び該治療方法に使用する組成物 Pending JP2004525140A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US27843501P 2001-03-26 2001-03-26
CA 2342472 CA2342472A1 (en) 2001-03-30 2001-03-30 Ram having dynamically switchable addressing modes
PCT/AU2002/000339 WO2002076454A1 (en) 2001-03-26 2002-03-20 Method for treatment of cancer and compositions for use therein

Publications (2)

Publication Number Publication Date
JP2004525140A true JP2004525140A (ja) 2004-08-19
JP2004525140A5 JP2004525140A5 (https=) 2006-01-05

Family

ID=25682475

Family Applications (1)

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JP2002574969A Pending JP2004525140A (ja) 2001-03-26 2002-03-20 ガンの治療方法及び該治療方法に使用する組成物

Country Status (4)

Country Link
US (1) US20050038022A1 (https=)
EP (1) EP1379242B1 (https=)
JP (1) JP2004525140A (https=)
WO (1) WO2002076454A1 (https=)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008511549A (ja) * 2004-08-31 2008-04-17 ニューサウス・イノベイションズ・プロプライエタリー・リミテッド Vegf阻害剤
JP2009510033A (ja) * 2005-09-27 2009-03-12 アバンテイス・フアルマ・エス・アー 新規ベンゾイミダゾール及びベンゾチアゾール誘導体、その調製方法、薬物としてのその使用、薬剤組成物、並びに特にc−met阻害剤としての新規使用
WO2018003829A1 (ja) * 2016-06-29 2018-01-04 国立大学法人東京大学 オートファジー阻害剤

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU7333701A (en) 2000-07-10 2002-01-21 Univ Texas Chromosome 3p21.3 genes are tumor suppressors
WO2002067932A1 (en) 2001-01-11 2002-09-06 Board Of Regents, The University Of Texas System Antihelminthic drugs as a treatment for hyperproliferative diseases
EP1581217A4 (en) * 2002-11-01 2007-07-11 Merck & Co Inc CARBONYLAMINO-BENZIMIDAZOLE DERIVATIVES AS MODULATORS OF ANDROGENIC RECEPTORS
CA2534649A1 (en) * 2003-08-01 2005-02-10 Genelabs Technologies, Inc. Bicyclic imidazol derivatives against flaviviridae
EP1723138B1 (en) * 2004-02-11 2010-07-14 Basilea Pharmaceutica AG Substituted benzimidazoles and their use for inducing apoptosis
FR2868421B1 (fr) 2004-04-01 2008-08-01 Aventis Pharma Sa Nouveaux benzothiazoles et leur utilisation comme medicaments
US20090286838A1 (en) * 2004-12-06 2009-11-19 Newsouth Innovations Pty Limited Treatment for cancer
ZA200705872B (en) * 2005-01-14 2008-09-25 Genelabs Tecnologies Inc Indole derivatives for treating viral infections
TW200720255A (en) * 2005-07-13 2007-06-01 Taiho Pharmaceutical Co Ltd Benzoimidazole compound capable of inhibiting prostaglandin d synthetase
PE20070335A1 (es) 2005-08-30 2007-04-21 Novartis Ag Benzimidazoles sustituidos y metodos para su preparacion
WO2009043093A1 (en) * 2007-10-04 2009-04-09 Newsouth Innovations Pty Limited Hif inhibition
US8835506B2 (en) 2008-06-05 2014-09-16 Stc.Unm Methods and related compositions for the treatment of cancer
EP2432451A2 (en) * 2009-05-20 2012-03-28 Children's Medical Center Corporation Compositions for the treatment of metastatic cancer and methods of use thereof
US8895596B2 (en) 2010-02-25 2014-11-25 Merck Sharp & Dohme Corp Cyclic benzimidazole derivatives useful as anti-diabetic agents
US11028055B2 (en) 2015-11-30 2021-06-08 Children's Medical Center Corporation Compounds for treating proliferative diseases
GB2559162A (en) * 2017-01-27 2018-08-01 Univ Bradford Compound for use in medicine
TW202214244A (zh) * 2020-08-10 2022-04-16 國立彰化師範大學 具有協同抗癌功效之氯硝柳胺(Niclosamide)和雙硫侖(Disulfiram)醫藥組合物及其用途
CN113648308A (zh) * 2021-09-14 2021-11-16 东莞市人民医院 奥芬达唑作为抗卵巢癌药物的应用

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998056387A1 (en) * 1997-06-10 1998-12-17 Unisearch Limited Method of treatment of liver tumours and pharmaceutical compositions for use therein
WO1999056697A2 (en) * 1998-05-04 1999-11-11 Unisearch Limited Pharmaceutical composition
WO2000041669A2 (en) * 1999-01-15 2000-07-20 Angiogene Pharmaceuticals Ltd. Benzimidazole vascular damaging agents
WO2001012169A2 (en) * 1999-08-13 2001-02-22 The Procter & Gamble Company Method of cancer treatment

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA962879B (en) * 1995-04-12 1997-03-17 Procter & Gamble A pharmaceutical composition for inhibiting the growth of viruses and cancers
US6287602B1 (en) * 1998-09-16 2001-09-11 Oncopharmaceutical, Inc. Treatment of oncologic tumors with an injectable formulation of a Golgi apparatus disturbing agent
PT1214052E (pt) * 1999-09-03 2004-12-31 Janssen Pharmaceutica Nv Formulacao veterinaria para a administracao de um medicamento insoluvel em agua a um animal visado, atraves de um sistema de distribuicao de agua
US6693125B2 (en) * 2001-01-24 2004-02-17 Combinatorx Incorporated Combinations of drugs (e.g., a benzimidazole and pentamidine) for the treatment of neoplastic disorders

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998056387A1 (en) * 1997-06-10 1998-12-17 Unisearch Limited Method of treatment of liver tumours and pharmaceutical compositions for use therein
WO1999056697A2 (en) * 1998-05-04 1999-11-11 Unisearch Limited Pharmaceutical composition
WO2000041669A2 (en) * 1999-01-15 2000-07-20 Angiogene Pharmaceuticals Ltd. Benzimidazole vascular damaging agents
WO2001012169A2 (en) * 1999-08-13 2001-02-22 The Procter & Gamble Company Method of cancer treatment

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008511549A (ja) * 2004-08-31 2008-04-17 ニューサウス・イノベイションズ・プロプライエタリー・リミテッド Vegf阻害剤
JP2009510033A (ja) * 2005-09-27 2009-03-12 アバンテイス・フアルマ・エス・アー 新規ベンゾイミダゾール及びベンゾチアゾール誘導体、その調製方法、薬物としてのその使用、薬剤組成物、並びに特にc−met阻害剤としての新規使用
WO2018003829A1 (ja) * 2016-06-29 2018-01-04 国立大学法人東京大学 オートファジー阻害剤

Also Published As

Publication number Publication date
US20050038022A1 (en) 2005-02-17
WO2002076454A1 (en) 2002-10-03
EP1379242A4 (en) 2007-10-03
EP1379242B1 (en) 2012-08-15
EP1379242A1 (en) 2004-01-14

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