JP2004524891A5 - - Google Patents
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- Publication number
- JP2004524891A5 JP2004524891A5 JP2002560547A JP2002560547A JP2004524891A5 JP 2004524891 A5 JP2004524891 A5 JP 2004524891A5 JP 2002560547 A JP2002560547 A JP 2002560547A JP 2002560547 A JP2002560547 A JP 2002560547A JP 2004524891 A5 JP2004524891 A5 JP 2004524891A5
- Authority
- JP
- Japan
- Prior art keywords
- body member
- cross
- biological agent
- stent
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 150000001875 compounds Chemical class 0.000 claims 43
- 239000003124 biologic agent Substances 0.000 claims 40
- 239000011248 coating agent Substances 0.000 claims 14
- 238000000576 coating method Methods 0.000 claims 14
- 229920000642 polymer Polymers 0.000 claims 9
- 239000000203 mixture Substances 0.000 claims 8
- 230000005855 radiation Effects 0.000 claims 8
- 239000000463 material Substances 0.000 claims 7
- GSNOZLZNQMLSKJ-UHFFFAOYSA-N Trapidil Chemical compound CCN(CC)C1=CC(C)=NC2=NC=NN12 GSNOZLZNQMLSKJ-UHFFFAOYSA-N 0.000 claims 6
- 229960000363 trapidil Drugs 0.000 claims 6
- 102000004457 Granulocyte-Macrophage Colony-Stimulating Factor Human genes 0.000 claims 5
- 108010017213 Granulocyte-Macrophage Colony-Stimulating Factor Proteins 0.000 claims 5
- 229920001577 copolymer Polymers 0.000 claims 5
- 150000003839 salts Chemical class 0.000 claims 5
- 150000002433 hydrophilic molecules Chemical class 0.000 claims 4
- 230000002209 hydrophobic effect Effects 0.000 claims 4
- 238000004519 manufacturing process Methods 0.000 claims 4
- 239000011159 matrix material Substances 0.000 claims 4
- 230000001934 delay Effects 0.000 claims 3
- 229930012538 Paclitaxel Natural products 0.000 claims 2
- 238000004132 cross linking Methods 0.000 claims 2
- 238000002594 fluoroscopy Methods 0.000 claims 2
- 230000001678 irradiating effect Effects 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 229960001592 paclitaxel Drugs 0.000 claims 2
- ZAHRKKWIAAJSAO-UHFFFAOYSA-N rapamycin Natural products COCC(O)C(=C/C(C)C(=O)CC(OC(=O)C1CCCCN1C(=O)C(=O)C2(O)OC(CC(OC)C(=CC=CC=CC(C)CC(C)C(=O)C)C)CCC2C)C(C)CC3CCC(O)C(C3)OC)C ZAHRKKWIAAJSAO-UHFFFAOYSA-N 0.000 claims 2
- QFJCIRLUMZQUOT-HPLJOQBZSA-N sirolimus Chemical compound C1C[C@@H](O)[C@H](OC)C[C@@H]1C[C@@H](C)[C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@](O)(O2)[C@H](C)CC[C@H]2C[C@H](OC)/C(C)=C/C=C/C=C/[C@@H](C)C[C@@H](C)C(=O)[C@H](OC)[C@H](O)/C(C)=C/[C@@H](C)C(=O)C1 QFJCIRLUMZQUOT-HPLJOQBZSA-N 0.000 claims 2
- 229960002930 sirolimus Drugs 0.000 claims 2
- 230000008878 coupling Effects 0.000 claims 1
- 238000010168 coupling process Methods 0.000 claims 1
- 238000005859 coupling reaction Methods 0.000 claims 1
- 238000005530 etching Methods 0.000 claims 1
- 229920006242 ethylene acrylic acid copolymer Polymers 0.000 claims 1
- 238000001727 in vivo Methods 0.000 claims 1
- 238000003698 laser cutting Methods 0.000 claims 1
- RCINICONZNJXQF-MZXODVADSA-N taxol Chemical compound O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 claims 1
- 125000002456 taxol group Chemical group 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US77107301A | 2001-01-29 | 2001-01-29 | |
| US10/039,816 US20020099438A1 (en) | 1998-04-15 | 2001-10-26 | Irradiated stent coating |
| PCT/US2001/044136 WO2002060350A1 (en) | 2001-01-29 | 2001-11-09 | Irradiated stent coating |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004524891A JP2004524891A (ja) | 2004-08-19 |
| JP2004524891A5 true JP2004524891A5 (https=) | 2005-11-17 |
Family
ID=26716477
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002560547A Pending JP2004524891A (ja) | 2001-01-29 | 2001-11-09 | 照射ステントコーティング |
Country Status (4)
| Country | Link |
|---|---|
| US (2) | US20020099438A1 (https=) |
| EP (1) | EP1359864A4 (https=) |
| JP (1) | JP2004524891A (https=) |
| WO (1) | WO2002060350A1 (https=) |
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-
2001
- 2001-10-26 US US10/039,816 patent/US20020099438A1/en not_active Abandoned
- 2001-11-09 EP EP01273621A patent/EP1359864A4/en not_active Withdrawn
- 2001-11-09 WO PCT/US2001/044136 patent/WO2002060350A1/en not_active Ceased
- 2001-11-09 JP JP2002560547A patent/JP2004524891A/ja active Pending
-
2004
- 2004-03-26 US US10/810,356 patent/US8603158B2/en not_active Expired - Fee Related
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