JP2004523517A - 腫瘍増殖および転移を調節するための方法 - Google Patents

腫瘍増殖および転移を調節するための方法 Download PDF

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Publication number
JP2004523517A
JP2004523517A JP2002557211A JP2002557211A JP2004523517A JP 2004523517 A JP2004523517 A JP 2004523517A JP 2002557211 A JP2002557211 A JP 2002557211A JP 2002557211 A JP2002557211 A JP 2002557211A JP 2004523517 A JP2004523517 A JP 2004523517A
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JP
Japan
Prior art keywords
combretastatin
pharmaceutical composition
agent
compound
anticancer agent
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Pending
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JP2002557211A
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English (en)
Japanese (ja)
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JP2004523517A5 (https=
Inventor
フランシス ワイ． リー，
ロナルド ペック，
デイビッド チャップリン，
ロナルド ペロ，
クラウス エバードセン，
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Bristol Myers Squibb Co
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Bristol Myers Squibb Co
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Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of JP2004523517A publication Critical patent/JP2004523517A/ja
Publication of JP2004523517A5 publication Critical patent/JP2004523517A5/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

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  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
JP2002557211A 2000-12-22 2001-12-20 腫瘍増殖および転移を調節するための方法 Pending JP2004523517A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25819500P 2000-12-22 2000-12-22
PCT/US2001/050261 WO2002056692A1 (en) 2000-12-22 2001-12-20 Methods for modulating tumor growth and metastasis

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2008315096A Division JP2009102350A (ja) 2000-12-22 2008-12-10 腫瘍増殖および転移を調節するための方法

Publications (2)

Publication Number Publication Date
JP2004523517A true JP2004523517A (ja) 2004-08-05
JP2004523517A5 JP2004523517A5 (https=) 2005-12-22

Family

ID=22979500

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2002557211A Pending JP2004523517A (ja) 2000-12-22 2001-12-20 腫瘍増殖および転移を調節するための方法
JP2008315096A Pending JP2009102350A (ja) 2000-12-22 2008-12-10 腫瘍増殖および転移を調節するための方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2008315096A Pending JP2009102350A (ja) 2000-12-22 2008-12-10 腫瘍増殖および転移を調節するための方法

Country Status (5)

Country Link
EP (1) EP1351573A4 (https=)
JP (2) JP2004523517A (https=)
AU (1) AU2002246827B2 (https=)
CA (1) CA2432792C (https=)
WO (1) WO2002056692A1 (https=)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009102350A (ja) * 2000-12-22 2009-05-14 Bristol Myers Squibb Co 腫瘍増殖および転移を調節するための方法
JP2015091826A (ja) * 2007-10-10 2015-05-14 アンスティテュ、ナショナル、ド、ラ、サント、エ、ド、ラ、ルシェルシュ、メディカル（アンセルム）Ｉｎｓｔｉｔｕｔ Ｎａｔｉｏｎａｌ Ｄｅ Ｌａ Ｓａｎｔｅ Ｅｔ Ｄｅ Ｌａ Ｒｅｃｈｅｒｃｈｅ Ｍｅｄｉｃａｌ （Ｉｎｓｅｒｍ） 癌治療用の組合せ製品
JP2019524637A (ja) * 2016-08-26 2019-09-05 トンクワン アンハオ ファーマシューティカル カンパニー リミテッド 抗腫瘍薬物の効果を有する併用薬物

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999051246A1 (en) 1998-04-03 1999-10-14 Ajinomoto Co., Inc. Antitumor agents
IL153218A0 (en) 2000-06-02 2003-07-06 Univ Texas Ethylenedicysteine (ec) -drug conjugates
AU1602902A (en) 2000-10-27 2002-05-06 Aventis Pharma Sa A combination comprising camptothecin and a stilbene derivative for the treatment of cancer
US20050209310A1 (en) * 2000-12-22 2005-09-22 Chaplin David J Methods for modulating tumor growth and metastasis
US20020183266A1 (en) * 2001-03-15 2002-12-05 Aventis Pharma, S.A. Combination comprising combretastatin and anticancer agents
JP2006503852A (ja) * 2002-09-25 2006-02-02 ユニバーシティー オブ ロチェスター 抗癌薬としてのカスパーゼインヒビター
WO2004032947A1 (en) * 2002-10-09 2004-04-22 Unibioscreen S.A. Extract with anti-tumor and anti-poisonous activity
TWI323662B (en) * 2002-11-15 2010-04-21 Telik Inc Combination cancer therapy with a gst-activated anticancer compound and another anticancer therapy
US9050378B2 (en) 2003-12-10 2015-06-09 Board Of Regents, The University Of Texas System N2S2 chelate-targeting ligand conjugates
US10925977B2 (en) 2006-10-05 2021-02-23 Ceil>Point, LLC Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
WO2009067706A1 (en) 2007-11-21 2009-05-28 Oxigene, Inc. Method for treating hematopoietic neoplasms
WO2009103076A1 (en) * 2008-02-15 2009-08-20 Oxigene, Inc. Methods and compositions for enhancing the efficacy of rtk inhibitors
FR2939665B1 (fr) 2008-12-12 2011-10-07 Sanofi Aventis Combinaison antitumorale associant l'ave8062a et le docetaxel
US11419934B2 (en) 2015-08-18 2022-08-23 Oncotelic Therapeutics, Inc. Use of VDAS to enhance immunomodulating therapies against tumors

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4996237A (en) 1987-01-06 1991-02-26 Arizona Board Of Regents Combretastatin A-4
CA1338645C (en) 1987-01-06 1996-10-15 George R. Pettit Isolation, structural elucidation and synthesis of novel antineoplastic substances denominated "combretastatins"
US5561122A (en) 1994-12-22 1996-10-01 Arizona Board Of Regents Acting On Behalf Of Arizona State University Combretastatin A-4 prodrug
EP1045853B1 (en) 1998-01-09 2010-08-04 ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA acting for and on behalf of ARIZONA STATE UNIVERSITY Synthesis of combretastatin a-4 prodrugs
GB9903404D0 (en) * 1999-02-16 1999-04-07 Angiogene Pharm Ltd Methods of treatment and compositions useful for the treatment of diseases involving angiogenesis
WO2000048606A1 (en) 1999-02-18 2000-08-24 Oxigene, Inc. Compositions and methods for use in targeting vascular destruction
AU2002246827B2 (en) * 2000-12-22 2008-02-21 Bristol-Myers Squibb Company Methods for modulating tumor growth and metastasis

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009102350A (ja) * 2000-12-22 2009-05-14 Bristol Myers Squibb Co 腫瘍増殖および転移を調節するための方法
JP2015091826A (ja) * 2007-10-10 2015-05-14 アンスティテュ、ナショナル、ド、ラ、サント、エ、ド、ラ、ルシェルシュ、メディカル（アンセルム）Ｉｎｓｔｉｔｕｔ Ｎａｔｉｏｎａｌ Ｄｅ Ｌａ Ｓａｎｔｅ Ｅｔ Ｄｅ Ｌａ Ｒｅｃｈｅｒｃｈｅ Ｍｅｄｉｃａｌ （Ｉｎｓｅｒｍ） 癌治療用の組合せ製品
JP2019524637A (ja) * 2016-08-26 2019-09-05 トンクワン アンハオ ファーマシューティカル カンパニー リミテッド 抗腫瘍薬物の効果を有する併用薬物

Also Published As

Publication number Publication date
WO2002056692A1 (en) 2002-07-25
AU2002246827B2 (en) 2008-02-21
CA2432792C (en) 2012-04-03
JP2009102350A (ja) 2009-05-14
CA2432792A1 (en) 2002-07-25
EP1351573A4 (en) 2007-03-28
EP1351573A1 (en) 2003-10-15

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