JP2004521608A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2004521608A5 JP2004521608A5 JP2002513885A JP2002513885A JP2004521608A5 JP 2004521608 A5 JP2004521608 A5 JP 2004521608A5 JP 2002513885 A JP2002513885 A JP 2002513885A JP 2002513885 A JP2002513885 A JP 2002513885A JP 2004521608 A5 JP2004521608 A5 JP 2004521608A5
- Authority
- JP
- Japan
- Prior art keywords
- polyunsaturated fatty
- fatty acid
- nucleotide sequence
- acid
- plant
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 235000020777 polyunsaturated fatty acids Nutrition 0.000 claims 54
- 238000004519 manufacturing process Methods 0.000 claims 33
- 239000002773 nucleotide Substances 0.000 claims 27
- 125000003729 nucleotide group Chemical group 0.000 claims 27
- 108090000790 Enzymes Proteins 0.000 claims 12
- 102000004190 Enzymes Human genes 0.000 claims 12
- MBMBGCFOFBJSGT-KUBAVDMBSA-N all-cis-docosa-4,7,10,13,16,19-hexaenoic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCC(O)=O MBMBGCFOFBJSGT-KUBAVDMBSA-N 0.000 claims 12
- 239000000758 substrate Substances 0.000 claims 8
- 238000000034 method Methods 0.000 claims 7
- 239000002253 acid Substances 0.000 claims 6
- 229940090949 docosahexaenoic acid Drugs 0.000 claims 6
- 235000020669 docosahexaenoic acid Nutrition 0.000 claims 6
- 230000009261 transgenic effect Effects 0.000 claims 6
- 102000004169 proteins and genes Human genes 0.000 claims 5
- 108090000623 proteins and genes Proteins 0.000 claims 5
- HOBAELRKJCKHQD-UHFFFAOYSA-N (8Z,11Z,14Z)-8,11,14-eicosatrienoic acid Natural products CCCCCC=CCC=CCC=CCCCCCCC(O)=O HOBAELRKJCKHQD-UHFFFAOYSA-N 0.000 claims 4
- -1 20: 4n-3 Chemical compound 0.000 claims 4
- HOBAELRKJCKHQD-QNEBEIHSSA-N dihomo-γ-linolenic acid Chemical compound CCCCC\C=C/C\C=C/C\C=C/CCCCCCC(O)=O HOBAELRKJCKHQD-QNEBEIHSSA-N 0.000 claims 4
- 239000000203 mixture Substances 0.000 claims 4
- 235000016709 nutrition Nutrition 0.000 claims 4
- 230000002265 prevention Effects 0.000 claims 4
- 230000000295 complement effect Effects 0.000 claims 3
- 102100034542 Acyl-CoA (8-3)-desaturase Human genes 0.000 claims 2
- 241000024188 Andala Species 0.000 claims 2
- 108010073542 Delta-5 Fatty Acid Desaturase Proteins 0.000 claims 2
- 101000912235 Rebecca salina Acyl-lipid (7-3)-desaturase Proteins 0.000 claims 2
- 101000877236 Siganus canaliculatus Acyl-CoA Delta-4 desaturase Proteins 0.000 claims 2
- 150000007513 acids Chemical class 0.000 claims 2
- 125000003275 alpha amino acid group Chemical group 0.000 claims 2
- 150000001413 amino acids Chemical class 0.000 claims 2
- 239000003937 drug carrier Substances 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 229920001184 polypeptide Polymers 0.000 claims 2
- 230000003449 preventive effect Effects 0.000 claims 2
- 102000004196 processed proteins & peptides Human genes 0.000 claims 2
- 108090000765 processed proteins & peptides Proteins 0.000 claims 2
- 208000024891 symptom Diseases 0.000 claims 2
- 238000002560 therapeutic procedure Methods 0.000 claims 2
- 235000015112 vegetable and seed oil Nutrition 0.000 claims 2
- 239000008158 vegetable oil Substances 0.000 claims 2
- 230000000694 effects Effects 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/624,670 US6913916B1 (en) | 1998-09-02 | 2000-07-24 | Elongase genes and uses thereof |
| US09/624,670 | 2000-07-24 | ||
| US09/903,456 | 2001-07-11 | ||
| US09/903,456 US6677145B2 (en) | 1998-09-02 | 2001-07-11 | Elongase genes and uses thereof |
| PCT/US2001/023259 WO2002008401A2 (en) | 2000-07-24 | 2001-07-24 | Elongase genes and uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2004521608A JP2004521608A (ja) | 2004-07-22 |
| JP2004521608A5 true JP2004521608A5 (https=) | 2005-03-03 |
| JP4959903B2 JP4959903B2 (ja) | 2012-06-27 |
Family
ID=27089733
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002513885A Expired - Fee Related JP4959903B2 (ja) | 2000-07-24 | 2001-07-24 | エロンガーゼ遺伝子およびその用途 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6677145B2 (https=) |
| EP (1) | EP1309699A2 (https=) |
| JP (1) | JP4959903B2 (https=) |
| AU (2) | AU7798201A (https=) |
| BR (1) | BR0112680A (https=) |
| CA (1) | CA2417484C (https=) |
| MX (1) | MXPA03000750A (https=) |
| WO (1) | WO2002008401A2 (https=) |
Families Citing this family (58)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6566583B1 (en) * | 1997-06-04 | 2003-05-20 | Daniel Facciotti | Schizochytrium PKS genes |
| US20030163845A1 (en) * | 1998-09-02 | 2003-08-28 | Pradip Mukerji | Elongase genes and uses thereof |
| US7247461B2 (en) | 1999-01-14 | 2007-07-24 | Martek Biosciences Corporation | Nucleic acid molecule encoding ORFA of a PUFA polyketide synthase system and uses thereof |
| US8003772B2 (en) * | 1999-01-14 | 2011-08-23 | Martek Biosciences Corporation | Chimeric PUFA polyketide synthase systems and uses thereof |
| US7217856B2 (en) * | 1999-01-14 | 2007-05-15 | Martek Biosciences Corporation | PUFA polyketide synthase systems and uses thereof |
| US7211418B2 (en) * | 1999-01-14 | 2007-05-01 | Martek Biosciences Corporation | PUFA polyketide synthase systems and uses thereof |
| US20070244192A1 (en) * | 1999-01-14 | 2007-10-18 | Martek Biosciences Corporation | Plant seed oils containing polyunsaturated fatty acids |
| GB0316629D0 (en) * | 2003-07-16 | 2003-08-20 | Univ York | Transgenic cell |
| GB0107510D0 (en) * | 2001-03-26 | 2001-05-16 | Univ Bristol | New elongase gene and a process for the production of -9-polyunsaturated fatty acids |
| US7045683B2 (en) * | 2001-05-04 | 2006-05-16 | Abbott Laboratories | Δ4-desaturase genes and uses thereof |
| AU2003224236A1 (en) * | 2002-03-16 | 2003-09-29 | The University Of York | Transgenic plants expressing enzymes involved in fatty acid biosynthesis |
| US20060189518A1 (en) * | 2002-06-26 | 2006-08-24 | Takeda Pharmaceutical Company Limited | Preventing/remedies for cancer |
| GB0229578D0 (en) * | 2002-12-19 | 2003-01-22 | Univ Bristol | Novel method for the production of polyunsaturated fatty acids |
| CA2510462A1 (en) * | 2002-12-19 | 2004-07-08 | University Of Bristol | Method for producing polyunsaturated fatty acids in a transgenic plant or microorganism comprising an introduced delta-9-elongase and a delta-8-desaturase |
| US8084074B2 (en) | 2003-02-12 | 2011-12-27 | E. I. Du Pont De Nemours And Company | Production of very long chain polyunsaturated fatty acids in oil seed plants |
| US20040172682A1 (en) | 2003-02-12 | 2004-09-02 | Kinney Anthony J. | Production of very long chain polyunsaturated fatty acids in oilseed plants |
| US20070082008A1 (en) * | 2003-03-07 | 2007-04-12 | Advanced Bionutrition Corporation | Feed formulation for terrestrial and aquatic animals |
| KR101234199B1 (ko) * | 2003-03-26 | 2013-02-20 | 마텍 바이오싸이언스스 코포레이션 | Ｐｕｆａ 폴리케타이드 신타제 시스템 및 이의 용도 |
| US7238482B2 (en) * | 2003-05-07 | 2007-07-03 | E. I. Du Pont De Nemours And Company | Production of polyunsaturated fatty acids in oleaginous yeasts |
| US7125672B2 (en) * | 2003-05-07 | 2006-10-24 | E. I. Du Pont De Nemours And Company | Codon-optimized genes for the production of polyunsaturated fatty acids in oleaginous yeasts |
| ES2713548T3 (es) * | 2003-08-01 | 2019-05-22 | Basf Plant Science Gmbh | Procedimiento para la producción de ácidos grasos poliinsaturados en organismos transgénicos |
| US7943816B2 (en) * | 2003-12-17 | 2011-05-17 | Suntory Holdings Limited | Arachidonic acid-containing plants and use of the plants |
| EP2623584B1 (de) * | 2004-02-27 | 2019-04-10 | BASF Plant Science GmbH | Verfahren zur Herstellung mehrfach ungesättigter Fettsäuren in transgenen Pflanzen |
| WO2005083053A2 (de) | 2004-02-27 | 2005-09-09 | Basf Plant Science Gmbh | Verfahren zur herstellung von ungesättigten omega-3-fettsäuren in transgenen organismen |
| CA3056110C (en) * | 2004-04-22 | 2020-07-14 | Surinder Pal Singh | Synthesis of long-chain polyunsaturated fatty acids by recombinant cells |
| DK1756280T3 (en) | 2004-04-22 | 2015-02-02 | Commw Scient Ind Res Org | SYNTHESIS OF CHAIN, polyunsaturated fatty acids BY RECOMBINANT CELLS |
| CA2568689A1 (en) * | 2004-06-04 | 2005-12-15 | Fluxome Sciences A/S | Metabolically engineered cells for the production of polyunsaturated fatty acids |
| US7138391B2 (en) * | 2004-08-09 | 2006-11-21 | Silverbrook Research Pty Ltd | Hydrophilizable and hydrophilic cyanine dyes |
| US7550286B2 (en) | 2004-11-04 | 2009-06-23 | E. I. Du Pont De Nemours And Company | Docosahexaenoic acid producing strains of Yarrowia lipolytica |
| WO2006092449A2 (en) * | 2005-03-02 | 2006-09-08 | Metanomics Gmbh | Process for the production of fine chemicals |
| DE102005013779A1 (de) | 2005-03-22 | 2006-09-28 | Basf Plant Science Gmbh | Verfahren zur Herstellung von mehrfach ungesättigten C20- und C22-Fettsäuren mit mindestens vier Doppelbindungen in transgenen Pflanzen |
| NZ563676A (en) * | 2005-05-23 | 2011-01-28 | Arcadia Biosciences Inc | Safflower with elevated gamma-linolenic acid |
| DE102005038036A1 (de) | 2005-08-09 | 2007-02-15 | Basf Plant Science Gmbh | Verfahren zur Herstellung von Arachidonsäure und/oder Eicosapentaensäure in transgenen Nutzpflanzen |
| US7470532B2 (en) * | 2005-10-19 | 2008-12-30 | E.I. Du Pont De Nemours And Company | Mortierella alpina C16/18 fatty acid elongase |
| DK1951866T3 (da) | 2005-11-23 | 2014-10-27 | Du Pont | Delta-9-elongaser og anvendelse heraf til fremstilling af flerumættede fedtsyrer |
| GB0603160D0 (en) | 2006-02-16 | 2006-03-29 | Rothamsted Res Ltd | Nucleic acid |
| AR059376A1 (es) | 2006-02-21 | 2008-03-26 | Basf Plant Science Gmbh | Procedimiento para la produccion de acidos grasos poliinsaturados |
| KR101524398B1 (ko) | 2006-03-15 | 2015-06-04 | 디에스엠 아이피 어셋츠 비.브이. | Ｐｕｆａ 폴리케티드 신타제 시스템을 이용한 이종 생물체내 다불포화 지방산의 제조 |
| US7943823B2 (en) | 2006-04-28 | 2011-05-17 | E.I. Du Pont De Nemours And Company | Delta-8 desaturase and its use in making polyunsaturated fatty acids |
| US7678560B2 (en) * | 2006-05-17 | 2010-03-16 | E.I. Du Pont De Nemours And Company | Δ 5 desaturase and its use in making polyunsaturated fatty acids |
| US7695950B2 (en) * | 2006-05-17 | 2010-04-13 | E. I. Du Pont De Nemours And Company | Δ5 desaturase and its use in making polyunsaturated fatty acids |
| CN101578363A (zh) | 2006-08-29 | 2009-11-11 | 联邦科学技术研究组织 | 脂肪酸的合成 |
| EP2182056B1 (de) | 2006-10-06 | 2015-12-23 | BASF Plant Science GmbH | Verfahren zur Herstellung mehrfach ungesättigter Fettsäuren in transgenen nicht-humanen Organismen |
| US8389808B2 (en) | 2007-02-12 | 2013-03-05 | E.I. Du Pont De Nemours And Company | Production of arachidonic acid in oilseed plants |
| ES2559312T3 (es) * | 2007-04-03 | 2016-02-11 | E. I. Du Pont De Nemours And Company | Multienzimas y su uso en la fabricación de ácidos grasos poliinsaturados |
| JP2010532418A (ja) * | 2007-06-29 | 2010-10-07 | マーテック バイオサイエンシーズ コーポレーション | 多価不飽和脂肪酸のエステルの製造方法および精製方法 |
| CA2695112A1 (en) * | 2007-07-31 | 2009-02-05 | Basf Plant Science Gmbh | Elongases and processes for the production of polyunsaturated fatty acids in transgenic organisms |
| US8168858B2 (en) * | 2008-06-20 | 2012-05-01 | E. I. Du Pont De Nemours And Company | Delta-9 fatty acid elongase genes and their use in making polyunsaturated fatty acids |
| US9090902B2 (en) | 2008-08-26 | 2015-07-28 | Basf Plant Science Gmbh | Nucleic acids encoding desaturases and modified plant oil |
| NO2358882T3 (https=) | 2008-11-18 | 2017-12-23 | ||
| ES2717102T3 (es) * | 2009-03-19 | 2019-06-19 | Dsm Ip Assets Bv | Moléculas de ácido nucleico de ácido graso poliinsaturado sintasas, y polipéptidos, composiciones y métodos de preparación y usos de los mismos |
| US20120247066A1 (en) | 2011-04-01 | 2012-10-04 | Ice House America, Llc | Ice bagging apparatus and methods |
| US8183227B1 (en) | 2011-07-07 | 2012-05-22 | Chemo S. A. France | Compositions, kits and methods for nutrition supplementation |
| US8168611B1 (en) | 2011-09-29 | 2012-05-01 | Chemo S.A. France | Compositions, kits and methods for nutrition supplementation |
| PL2861059T3 (pl) | 2012-06-15 | 2017-10-31 | Commw Scient Ind Res Org | Wytwarzanie długołańcuchowych wielonienasyconych kwasów tłuszczowych w komórkach roślinnych |
| NZ721036A (en) | 2013-12-18 | 2023-07-28 | Grains Res & Dev Corp | Lipid comprising long chain polyunsaturated fatty acids |
| PH12016502586B1 (en) | 2014-06-27 | 2023-07-19 | Commw Scient Ind Res Org | Lipid comprising docosapentaenoic acid |
| CN110373436B (zh) * | 2018-12-11 | 2022-09-23 | 山东理工大学 | 一种产双高-γ-亚麻酸卷枝毛霉细胞工厂的构建方法及发酵技术 |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4943674A (en) | 1987-05-26 | 1990-07-24 | Calgene, Inc. | Fruit specific transcriptional factors |
| US5420034A (en) | 1986-07-31 | 1995-05-30 | Calgene, Inc. | Seed-specific transcriptional regulation |
| GB8507058D0 (en) | 1985-03-19 | 1985-04-24 | Efamol Ltd | Pharmaceutical & dietary compositions |
| GB8524275D0 (en) | 1985-10-02 | 1985-11-06 | Efamol Ltd | Pharmaceutical & dietary compositions |
| GB8524276D0 (en) | 1985-10-02 | 1985-11-06 | Efamol Ltd | Pharmaceutical & dietary compositions |
| US5188958A (en) | 1986-05-29 | 1993-02-23 | Calgene, Inc. | Transformation and foreign gene expression in brassica species |
| EP0285405A1 (en) | 1987-03-31 | 1988-10-05 | Schering Biotech Corporation | Glycosylation inhibition factors |
| GB8714772D0 (en) * | 1987-06-24 | 1987-07-29 | Efamol Ltd | Essential fatty acid compositions |
| US5116871A (en) | 1988-09-13 | 1992-05-26 | Efamol Holdings Plc | Fatty acid therapy and compositions for the treatment of myalgic encephalomyelitis |
| US5106739A (en) | 1989-04-18 | 1992-04-21 | Calgene, Inc. | CaMv 355 enhanced mannopine synthase promoter and method for using same |
| US5196198A (en) | 1989-06-02 | 1993-03-23 | Abbott Laboratories | Parenteral nutrition product |
| FR2648347B1 (fr) * | 1989-06-15 | 1994-04-29 | Sederma Sa | Preparations cosmetiques possedant des proprietes adoucissantes |
| US5175095A (en) | 1989-07-19 | 1992-12-29 | Calgene, Inc. | Ovary-tissue transcriptional factors |
| WO1991018985A1 (en) | 1990-05-25 | 1991-12-12 | E.I. Du Pont De Nemours And Company | Nucleotide sequence of soybean stearoyl-acp desaturase gene |
| PH31293A (en) | 1991-10-10 | 1998-07-06 | Rhone Poulenc Agrochimie | Production of y-linolenic acid by a delta6-desaturage. |
| CA2124673C (en) | 1991-12-04 | 2008-08-05 | John Browse | Fatty acid desaturase genes from plants |
| DK0668919T3 (da) | 1992-11-17 | 2003-09-15 | Du Pont | Gener for mikorsomale delta-12-fedtsyredesaturaser og beslægtede enzymer fra planter |
| DK0686197T3 (da) | 1993-02-26 | 2000-09-04 | Calgene Llc | Geminivirusbaseret genekspressionssystem |
| US5750176A (en) | 1994-03-09 | 1998-05-12 | Abbott Laboratories | Transgenic non-human mammal milk comprising 2'-fucosyl-lactose |
| WO1995024494A1 (en) | 1994-03-09 | 1995-09-14 | Abbott Laboratories | Humanized milk |
| AU692841B2 (en) | 1994-03-09 | 1998-06-18 | Abbott Laboratories | Transgenic animals producing oligosaccharides and glycoconjugates |
| US5484724A (en) | 1994-05-26 | 1996-01-16 | Merck & Co., Inc. | DNA encoding GLSI |
| US5654402A (en) | 1994-10-26 | 1997-08-05 | Michigan State University | Methods and compositions relating to plant Δ6 palmitoyl-acyl carrier protein desaturase |
| WO1998039448A2 (en) | 1997-03-07 | 1998-09-11 | Human Genome Sciences, Inc. | 186 human secreted proteins |
| US5972664A (en) * | 1997-04-11 | 1999-10-26 | Abbott Laboratories | Methods and compositions for synthesis of long chain poly-unsaturated fatty acids |
| US6403349B1 (en) * | 1998-09-02 | 2002-06-11 | Abbott Laboratories | Elongase gene and uses thereof |
| WO2000070945A2 (en) * | 1999-05-20 | 2000-11-30 | Karolinska Innovations Ab | Fatty acid elongation genes and uses thereof |
| EE200200443A (et) * | 2000-02-09 | 2003-12-15 | Basf Aktiengesellschaft | Uus elongaasigeen ning polüküllastumata rasvhapete saamise meetod |
-
2001
- 2001-07-11 US US09/903,456 patent/US6677145B2/en not_active Expired - Lifetime
- 2001-07-24 EP EP01955933A patent/EP1309699A2/en not_active Withdrawn
- 2001-07-24 AU AU7798201A patent/AU7798201A/xx active Pending
- 2001-07-24 CA CA2417484A patent/CA2417484C/en not_active Expired - Fee Related
- 2001-07-24 AU AU2001277982A patent/AU2001277982B2/en not_active Ceased
- 2001-07-24 MX MXPA03000750A patent/MXPA03000750A/es active IP Right Grant
- 2001-07-24 JP JP2002513885A patent/JP4959903B2/ja not_active Expired - Fee Related
- 2001-07-24 WO PCT/US2001/023259 patent/WO2002008401A2/en not_active Ceased
- 2001-07-24 BR BR0112680-6A patent/BR0112680A/pt not_active IP Right Cessation
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2004521608A5 (https=) | ||
| JP2002523098A5 (https=) | ||
| CA2446439A1 (en) | .delta.4-desaturase genes and uses thereof | |
| CA2474894A1 (en) | Desaturase genes, enzymes encoded thereby, and uses thereof | |
| CA2435685A1 (en) | Desaturase genes and uses thereof | |
| EP1911837B1 (en) | FAD5-2 fatty acid desaturase family member and uses thereof | |
| CA2417484A1 (en) | Elongase genes and uses thereof | |
| CA2487095A1 (en) | Elongase genes and uses thereof | |
| JP4453881B2 (ja) | 長鎖多不飽和脂肪酸の合成のための方法および組成物 | |
| CA2633516C (en) | Elongase genes and uses thereof | |
| AU780422B2 (en) | Human desaturase gene and uses thereof | |
| CA2285939A1 (en) | Methods and compositions for synthesis of long chain polyunsaturated fatty acids in plants | |
| JP2001523091A (ja) | 長鎖多不飽和脂肪酸の合成のための方法および組成物 | |
| JP2002522088A5 (https=) | ||
| WO2000020603A1 (en) | Altered fatty acid biosynthesis in insect cells using delta five desaturase | |
| JP2002508932A (ja) | デサチュラーゼ | |
| CN101353661B (zh) | 具有△6脂肪酸脱氢酶功能的基因及其应用 | |
| EP0822988A2 (fr) | Lipases preduodenales recombinantes et polypeptides derives produits par les plantes, leurs procedes d'obtention et leurs utilisations | |
| RU2011114558A (ru) | Гены δ-8-десатуразы, ферменты, кодируемые ими, и их применение | |
| CN101921784B (zh) | 具有δ6脂肪酸脱氢酶功能的基因及其应用 | |
| KR20030088206A (ko) | 디글리세리드의 효소적 제조방법 | |
| CA2608848C (en) | Fad4, fad5, fad5-2, and fad6, novel fatty acid desaturase family members and uses thereof | |
| CN120733003A (zh) | 高效身体机能修复活性小分子肽制剂及其制备方法 | |
| KR101570771B1 (ko) | 고도불포화지방산 생합성을 위한 재조합 벡터 및 이를 이용하여 제작된 형질전환 식물체 | |
| RU2000116010A (ru) | Десатураза |