JP2004520041A - 新規アッセイ - Google Patents

新規アッセイ Download PDF

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Publication number
JP2004520041A
JP2004520041A JP2002558535A JP2002558535A JP2004520041A JP 2004520041 A JP2004520041 A JP 2004520041A JP 2002558535 A JP2002558535 A JP 2002558535A JP 2002558535 A JP2002558535 A JP 2002558535A JP 2004520041 A JP2004520041 A JP 2004520041A
Authority
JP
Japan
Prior art keywords
bace
nogo
polypeptide
activity
modulator
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2002558535A
Other languages
English (en)
Japanese (ja)
Other versions
JP2004520041A5 (https=
Inventor
ブラックストック,ウォルター,フィリップ
ヘール,リチャード,スティーブン
プリンジャ,ラビンダー
ローリー,アデル
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Ltd
Glaxo Group Ltd
Original Assignee
SmithKline Beecham Ltd
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Ltd, Glaxo Group Ltd filed Critical SmithKline Beecham Ltd
Publication of JP2004520041A publication Critical patent/JP2004520041A/ja
Publication of JP2004520041A5 publication Critical patent/JP2004520041A5/ja
Pending legal-status Critical Current

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896Neurological disorders, e.g. Alzheimer's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
JP2002558535A 2001-01-18 2002-01-18 新規アッセイ Pending JP2004520041A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0101312.7A GB0101312D0 (en) 2001-01-18 2001-01-18 Assay
PCT/GB2002/000228 WO2002057483A2 (en) 2001-01-18 2002-01-18 Method of identifying modulators of nogo-functions

Publications (2)

Publication Number Publication Date
JP2004520041A true JP2004520041A (ja) 2004-07-08
JP2004520041A5 JP2004520041A5 (https=) 2005-12-22

Family

ID=9907052

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2002558535A Pending JP2004520041A (ja) 2001-01-18 2002-01-18 新規アッセイ

Country Status (6)

Country Link
US (2) US7270962B2 (https=)
EP (1) EP1390758A2 (https=)
JP (1) JP2004520041A (https=)
AU (1) AU2002225174A1 (https=)
GB (1) GB0101312D0 (https=)
WO (1) WO2002057483A2 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011130347A2 (en) * 2010-04-13 2011-10-20 The Johns Hopkins University Methods for enhancing axonal regeneration
CN119768424A (zh) * 2022-08-22 2025-04-04 舒泰神(北京)生物制药股份有限公司 特异性识别Nogo-A的抗体及其应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ304224B6 (cs) * 1998-11-06 2014-01-15 Schwab Monoklonální protilátka
US7087399B1 (en) * 1999-05-13 2006-08-08 Scios, Inc. β-secretase and modulation of β-secretase activity
IL150566A0 (en) 2000-01-12 2003-02-12 Univ Yale Nucleic acids and polypeptides and nogo-receptor proteins
GB0101313D0 (en) 2001-01-18 2001-02-28 Glaxo Group Ltd Assay

Also Published As

Publication number Publication date
GB0101312D0 (en) 2001-02-28
US7270962B2 (en) 2007-09-18
US20070286851A1 (en) 2007-12-13
US20040132096A1 (en) 2004-07-08
WO2002057483A2 (en) 2002-07-25
WO2002057483A3 (en) 2003-04-24
EP1390758A2 (en) 2004-02-25
AU2002225174A1 (en) 2002-07-30

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