JP2004519488A5 - - Google Patents

Info

Publication number

JP2004519488A5

JP2004519488A5 JP2002571051A JP2002571051A JP2004519488A5 JP 2004519488 A5 JP2004519488 A5 JP 2004519488A5 JP 2002571051 A JP2002571051 A JP 2002571051A JP 2002571051 A JP2002571051 A JP 2002571051A JP 2004519488 A5 JP2004519488 A5 JP 2004519488A5

Authority

JP

Japan

Prior art keywords

composition

nicotinic acid

acid ester

subject

carbon atoms

Prior art date

2002-03-08

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Links

• Espacenet
• Global Dossier
• Discuss

• 239000000203 mixture Substances 0.000 claims 16
• PVNIIMVLHYAWGP-UHFFFAOYSA-N Niacin Chemical compound OC(=O)C1=CC=CN=C1 PVNIIMVLHYAWGP-UHFFFAOYSA-N 0.000 claims 11
• 229960003512 nicotinic acid Drugs 0.000 claims 8
• 235000001968 nicotinic acid Nutrition 0.000 claims 8
• 239000011664 nicotinic acid Substances 0.000 claims 8
• -1 nicotinic acid ester Chemical class 0.000 claims 6
• 102000016267 Leptin Human genes 0.000 claims 3
• 108010092277 Leptin Proteins 0.000 claims 3
• 125000000217 alkyl group Chemical group 0.000 claims 3
• 125000004432 carbon atom Chemical group C* 0.000 claims 3
• NRYBAZVQPHGZNS-ZSOCWYAHSA-N leptin Chemical compound O=C([C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC=1C2=CC=CC=C2NC=1)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](N)CC(C)C)CCSC)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CS)C(O)=O NRYBAZVQPHGZNS-ZSOCWYAHSA-N 0.000 claims 3
• 229940039781 leptin Drugs 0.000 claims 3
• 206010072170 Skin wound Diseases 0.000 claims 1
• 239000008194 pharmaceutical composition Substances 0.000 claims 1