ATE409037T1 - Verfahren zur erhöhung der leptinspiegel unter verwendung von nikotinsäureverbindungen - Google Patents
Verfahren zur erhöhung der leptinspiegel unter verwendung von nikotinsäureverbindungenInfo
- Publication number
- ATE409037T1 ATE409037T1 AT02721337T AT02721337T ATE409037T1 AT E409037 T1 ATE409037 T1 AT E409037T1 AT 02721337 T AT02721337 T AT 02721337T AT 02721337 T AT02721337 T AT 02721337T AT E409037 T1 ATE409037 T1 AT E409037T1
- Authority
- AT
- Austria
- Prior art keywords
- nicotinic acid
- leptin levels
- acid compounds
- increase
- increase leptin
- Prior art date
Links
- PVNIIMVLHYAWGP-UHFFFAOYSA-N Niacin Chemical class OC(=O)C1=CC=CN=C1 PVNIIMVLHYAWGP-UHFFFAOYSA-N 0.000 title abstract 8
- 102000016267 Leptin Human genes 0.000 title abstract 3
- 108010092277 Leptin Proteins 0.000 title abstract 3
- NRYBAZVQPHGZNS-ZSOCWYAHSA-N leptin Chemical compound O=C([C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC=1C2=CC=CC=C2NC=1)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](N)CC(C)C)CCSC)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CS)C(O)=O NRYBAZVQPHGZNS-ZSOCWYAHSA-N 0.000 title abstract 3
- 229940039781 leptin Drugs 0.000 title abstract 3
- 229960003512 nicotinic acid Drugs 0.000 abstract 4
- 235000001968 nicotinic acid Nutrition 0.000 abstract 4
- 239000011664 nicotinic acid Substances 0.000 abstract 4
- 206010052428 Wound Diseases 0.000 abstract 1
- 208000027418 Wounds and injury Diseases 0.000 abstract 1
- -1 nicotinic acid ester Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Child & Adolescent Psychology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US27434901P | 2001-03-08 | 2001-03-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE409037T1 true ATE409037T1 (de) | 2008-10-15 |
Family
ID=23047813
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02721337T ATE409037T1 (de) | 2001-03-08 | 2002-03-08 | Verfahren zur erhöhung der leptinspiegel unter verwendung von nikotinsäureverbindungen |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US6750234B2 (enExample) |
| EP (1) | EP1365762B1 (enExample) |
| JP (1) | JP5057353B2 (enExample) |
| CN (1) | CN1265792C (enExample) |
| AT (1) | ATE409037T1 (enExample) |
| CA (1) | CA2437844C (enExample) |
| DE (1) | DE60229041D1 (enExample) |
| DK (1) | DK1365762T3 (enExample) |
| ES (1) | ES2315358T3 (enExample) |
| MX (1) | MXPA03008096A (enExample) |
| PT (1) | PT1365762E (enExample) |
| WO (1) | WO2002072092A1 (enExample) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1383540T3 (da) | 2000-07-31 | 2009-08-24 | Univ Bar Ilan | Fremgangsmdåer og farmaceutiske sammensætninger til sårheling |
| US20040037828A1 (en) | 2002-07-09 | 2004-02-26 | Bar-Ilan University | Methods and pharmaceutical compositions for healing wounds |
| ES2315358T3 (es) * | 2001-03-08 | 2009-04-01 | University Of Kentucky Research Foundation | Metodo para incrementar los niveles de leptina usando compuestos de acido nicotinico. |
| AU2003299568B2 (en) * | 2002-11-27 | 2010-07-22 | Ampio Pharmaceuticals, Inc. | Treatment of diseases and conditions mediated by increased phosphorylation |
| US7736636B2 (en) * | 2003-02-12 | 2010-06-15 | Shaker Mousa | Method for treating occlusive vascular diseases & wound healing |
| US7218948B2 (en) | 2003-02-24 | 2007-05-15 | Qualcomm Incorporated | Method of transmitting pilot tones in a multi-sector cell, including null pilot tones, for generating channel quality indicators |
| US9544860B2 (en) | 2003-02-24 | 2017-01-10 | Qualcomm Incorporated | Pilot signals for use in multi-sector cells |
| US8811348B2 (en) | 2003-02-24 | 2014-08-19 | Qualcomm Incorporated | Methods and apparatus for generating, communicating, and/or using information relating to self-noise |
| CA2535029C (en) | 2003-08-07 | 2013-07-16 | Healor Ltd. | Pharmaceutical compositions and methods for accelerating wound healing |
| US8969291B2 (en) | 2004-10-08 | 2015-03-03 | Enzo Therapeutics, Inc. | Methods for decreasing leptin levels or activity for treating inflammation |
| US8503938B2 (en) | 2004-10-14 | 2013-08-06 | Qualcomm Incorporated | Methods and apparatus for determining, communicating and using information including loading factors which can be used for interference control purposes |
| EP1810409A4 (en) | 2004-10-14 | 2012-07-04 | Qualcomm Inc | METHOD AND DEVICES FOR DETERMINING, TRANSMITTING AND USING INFORMATION THAT MAY BE USED FOR TROUBLESHOOTING PURPOSES |
| JP2006253769A (ja) * | 2005-03-08 | 2006-09-21 | National Institute Of Advanced Industrial & Technology | 情報処理システムおよび方法 |
| JP4956534B2 (ja) * | 2005-06-24 | 2012-06-20 | アリゾナ・ボード・オブ・リージェンツ・オン・ビハーフ・オブ・ザ・ユニバーシティ・オブ・アリゾナ | 女性型脱毛症等の毛髪成長障害の治療方法とそのために有用な組成物 |
| US8367606B2 (en) | 2005-08-29 | 2013-02-05 | Healor Ltd. | Method and compositions for prevention and treatment of diabetic and aged skin |
| US20070066512A1 (en) * | 2005-09-12 | 2007-03-22 | Dominique Verhelle | Methods and compositions using immunomodulatory compounds for the treatment of disorders associated with low plasma leptin levels |
| US8989084B2 (en) | 2005-10-14 | 2015-03-24 | Qualcomm Incorporated | Methods and apparatus for broadcasting loading information corresponding to neighboring base stations |
| US9191840B2 (en) | 2005-10-14 | 2015-11-17 | Qualcomm Incorporated | Methods and apparatus for determining, communicating and using information which can be used for interference control |
| US9125093B2 (en) | 2005-12-22 | 2015-09-01 | Qualcomm Incorporated | Methods and apparatus related to custom control channel reporting formats |
| US9148795B2 (en) | 2005-12-22 | 2015-09-29 | Qualcomm Incorporated | Methods and apparatus for flexible reporting of control information |
| US9451491B2 (en) | 2005-12-22 | 2016-09-20 | Qualcomm Incorporated | Methods and apparatus relating to generating and transmitting initial and additional control information report sets in a wireless system |
| US9137072B2 (en) | 2005-12-22 | 2015-09-15 | Qualcomm Incorporated | Methods and apparatus for communicating control information |
| US9125092B2 (en) | 2005-12-22 | 2015-09-01 | Qualcomm Incorporated | Methods and apparatus for reporting and/or using control information |
| US9338767B2 (en) | 2005-12-22 | 2016-05-10 | Qualcomm Incorporated | Methods and apparatus of implementing and/or using a dedicated control channel |
| US8437251B2 (en) | 2005-12-22 | 2013-05-07 | Qualcomm Incorporated | Methods and apparatus for communicating transmission backlog information |
| US9119220B2 (en) | 2005-12-22 | 2015-08-25 | Qualcomm Incorporated | Methods and apparatus for communicating backlog related information |
| US8514771B2 (en) | 2005-12-22 | 2013-08-20 | Qualcomm Incorporated | Methods and apparatus for communicating and/or using transmission power information |
| US9473265B2 (en) | 2005-12-22 | 2016-10-18 | Qualcomm Incorporated | Methods and apparatus for communicating information utilizing a plurality of dictionaries |
| US7801589B2 (en) | 2005-12-22 | 2010-09-21 | Olympus Corporation | In-vivo examination method and in-vivo examination apparatus |
| US20070253449A1 (en) | 2005-12-22 | 2007-11-01 | Arnab Das | Methods and apparatus related to determining, communicating, and/or using delay information |
| US9572179B2 (en) | 2005-12-22 | 2017-02-14 | Qualcomm Incorporated | Methods and apparatus for communicating transmission backlog information |
| US20070243882A1 (en) | 2006-04-12 | 2007-10-18 | Qualcomm Incorporated | Method and apparatus for locating a wireless local area network associated with a wireless wide area network |
| WO2008026349A1 (fr) * | 2006-08-31 | 2008-03-06 | Juridical Foundation Osaka Industrial Promotion Organization | Agent thérapeutique destiné au traitement de l'effluvium télogène |
| DK2120917T3 (da) * | 2007-02-28 | 2014-04-07 | Univ Kentucky Res Found | Fremgangsmåde til lindring af bivirkninger ved retinsyre-terapi og/eller til forbedring af effektivitet uden at interferere med effektiviteten |
| EP2523677A2 (en) | 2010-01-11 | 2012-11-21 | Healor Ltd. | Method for treatment of inflammatory disease and disorder |
| US11298334B2 (en) * | 2016-04-22 | 2022-04-12 | Jc (Wuxi) Company, Inc. | Use of isothiocyanate compounds |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4505896A (en) * | 1979-04-19 | 1985-03-19 | Elorac, Ltd. | Method of treating acne vulgaris and composition |
| DE3110611A1 (de) * | 1981-03-18 | 1982-10-07 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen | "mitogene der leukozyten und des entzuendungsgewebes:natuerliche leukopoetine zur selektiven anregung der teilung und differenzierung von leukozyten" |
| GB8330969D0 (en) * | 1983-11-21 | 1983-12-29 | Wellcome Found | Promoting healing |
| DE3570598D1 (en) * | 1984-11-15 | 1989-07-06 | Nitto Denko Corp | Composition for percutaneous administration |
| US4965252A (en) * | 1988-06-28 | 1990-10-23 | Hauser-Kuhrts, Inc. | Cholesterol-lowering combination compositions of guar gum and niacin |
| ATE198830T1 (de) * | 1991-03-01 | 2001-02-15 | Univ Florida | Verwendung von nikotinanalogen zur behandlung von degenerativen erkrankungen des nervensystems |
| US5240945A (en) * | 1992-02-18 | 1993-08-31 | Warshaw Thelma G | Method and compositions for treating acne |
| US5612382A (en) * | 1994-07-15 | 1997-03-18 | Frances B. Fike | Composition for percutaneous absorption of pharmaceutically active ingredients |
| US5496827A (en) * | 1994-07-15 | 1996-03-05 | Patrick; Jay | Compositions for the transdermal delivery of nutrients |
| US6068976A (en) * | 1995-03-20 | 2000-05-30 | Ligand Pharmaceuticals Incorporated | Modulators of ob gene and screening methods therefor |
| DK0823897T3 (da) * | 1995-05-01 | 2004-12-06 | Scarista Ltd | Nicotinsyreestere og farmaceutiske præparater indeholdende disse |
| WO1998052927A1 (en) * | 1997-05-19 | 1998-11-26 | Rosemarie Scivoletto | Composition for treating skin conditions |
| AU4672199A (en) * | 1998-05-20 | 1999-12-06 | Yale University | Modulation of angiogenesis and wound healing |
| ATE273008T1 (de) * | 1998-12-01 | 2004-08-15 | Univ Kentucky Res Found | Verwendung von nikotinsäurederivate zur behandlung von dna-schäden bei hautzellen |
| IT1306141B1 (it) * | 1999-05-17 | 2001-05-30 | Giampiero Valletta | Composizione per il trattamento del prurito uremico e di forme diprurito non riconducibili a lesioni organiche. |
| US6326034B1 (en) * | 1999-12-22 | 2001-12-04 | Natural Compounds Ltd | Natural extracted and synthetic antioxidant compositions |
| ES2315358T3 (es) * | 2001-03-08 | 2009-04-01 | University Of Kentucky Research Foundation | Metodo para incrementar los niveles de leptina usando compuestos de acido nicotinico. |
-
2002
- 2002-03-08 ES ES02721337T patent/ES2315358T3/es not_active Expired - Lifetime
- 2002-03-08 DE DE60229041T patent/DE60229041D1/de not_active Expired - Lifetime
- 2002-03-08 JP JP2002571051A patent/JP5057353B2/ja not_active Expired - Fee Related
- 2002-03-08 PT PT02721337T patent/PT1365762E/pt unknown
- 2002-03-08 CA CA002437844A patent/CA2437844C/en not_active Expired - Lifetime
- 2002-03-08 DK DK02721337T patent/DK1365762T3/da active
- 2002-03-08 EP EP02721337A patent/EP1365762B1/en not_active Expired - Lifetime
- 2002-03-08 US US10/094,063 patent/US6750234B2/en not_active Expired - Lifetime
- 2002-03-08 CN CNB028061209A patent/CN1265792C/zh not_active Expired - Fee Related
- 2002-03-08 WO PCT/US2002/007256 patent/WO2002072092A1/en not_active Ceased
- 2002-03-08 MX MXPA03008096A patent/MXPA03008096A/es active IP Right Grant
- 2002-03-08 AT AT02721337T patent/ATE409037T1/de active
-
2004
- 2004-04-14 US US10/825,405 patent/US20040198776A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| DE60229041D1 (de) | 2008-11-06 |
| EP1365762A1 (en) | 2003-12-03 |
| EP1365762B1 (en) | 2008-09-24 |
| ES2315358T3 (es) | 2009-04-01 |
| EP1365762A4 (en) | 2005-05-25 |
| US20040198776A1 (en) | 2004-10-07 |
| PT1365762E (pt) | 2008-11-27 |
| WO2002072092A1 (en) | 2002-09-19 |
| CN1265792C (zh) | 2006-07-26 |
| MXPA03008096A (es) | 2005-10-05 |
| US6750234B2 (en) | 2004-06-15 |
| CA2437844C (en) | 2007-05-15 |
| JP2004519488A (ja) | 2004-07-02 |
| HK1065941A1 (en) | 2005-03-11 |
| US20020128298A1 (en) | 2002-09-12 |
| CN1496260A (zh) | 2004-05-12 |
| DK1365762T3 (da) | 2008-11-17 |
| CA2437844A1 (en) | 2002-09-19 |
| JP5057353B2 (ja) | 2012-10-24 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE409037T1 (de) | Verfahren zur erhöhung der leptinspiegel unter verwendung von nikotinsäureverbindungen | |
| DE69936102D1 (de) | Verwendung von tnf-alpha inhibitoren zur behandlung von nervenwurzelschäden | |
| WO2001081312A3 (en) | Method of treatment using phenyl and biaryl derivatives as prostaglandin e inhibitors and compounds useful therefore | |
| DK1556083T3 (da) | Fremgangsmåde til behandling af post-operative smerter ved indgivelse af en antistof mod nervevækstfaktor og sammensætning indeholdende samme | |
| ATE241358T1 (de) | Verwendung von cholinesterasehemmer zur behandlung von konzentrationsstörungen | |
| ATE491444T1 (de) | Verfahren zur behandlung von schmerzen durch verabreichung eines nervenwachstumsfaktor- antagonisten und eines nsaid und diese enthaltende zusammensetzung | |
| ATE556711T1 (de) | Verfahren zur verbesserung der hautqualität | |
| ATE369845T1 (de) | Behandlung der nebenwirkungen von statinen | |
| ATE422943T1 (de) | Verfahren und verbindungen zur verstärkung der fybrozyten-bildung | |
| SE0301886D0 (sv) | New use V | |
| ATE521357T1 (de) | Verfahren zur behandlung von hepatitis | |
| DE60112766D1 (de) | Verwendung von derivaten der valproinsäureamide und 2-valproinsäureamid zur behandlung und prävention von schmerzen und/oder kopfschmerzen | |
| ATE260282T1 (de) | Aromatische ester von camptothecinen und verfahren zur behandlung von krebserkrankungen | |
| ATE435026T1 (de) | Verfahren zur prävention und behandlung von diabetes mit neurturin | |
| ATE515268T1 (de) | Verwendung von op-1 zur behandlung von knorpeldefekten | |
| ATE516027T1 (de) | Orazamid orotat zur vorbeugung von leberschäden | |
| ATE492275T1 (de) | Vitamin k zur vorbeugung und behandlung von hautausschlag infolge einer anti-egfr-therapie | |
| ATE444749T1 (de) | Benzothiazolium verbindungen zur verwendung in methoden zur hemmung der no produktion und von tnf alpha und zur behandlung von coronavirus infektionen | |
| ATE415965T1 (de) | Verwendung von verzweigtkettigen fettsäuren und ihrer derivate zur schmerzbehandlung | |
| DE69822626T8 (de) | Verwendung eines nitroxids oder seiner prodrugs zur prophylaktischen und therapeutischen behandlung von krebs | |
| ATE315387T1 (de) | Verwendung von substituierten 6- dimethylaminomethyl-1-phenyl- cyclohexanverbindungen zur therapie der harninkontinenz | |
| DE602006015373D1 (de) | Zusammensetzungen und Verfahren zur Prävention und Behandlung von immunvermittelten Entzündungskrankheiten | |
| DE60237594D1 (de) | Verwendung des abc-expressionspromotors pioglitazon zur behandlung von arteriosklerose obliterans | |
| DE602004016841D1 (de) | Verwendung von 2,2,3,3, tetramethylcyclopropane carbonsäure derivaten zur behandlung von psychiatrischen störungen | |
| DE602004014140D1 (de) | Verfahren zur behandlung von alkoholischer hepatitis |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1365762 Country of ref document: EP |