JP2004518704A5 - - Google Patents

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Publication number
JP2004518704A5
JP2004518704A5 JP2002563162A JP2002563162A JP2004518704A5 JP 2004518704 A5 JP2004518704 A5 JP 2004518704A5 JP 2002563162 A JP2002563162 A JP 2002563162A JP 2002563162 A JP2002563162 A JP 2002563162A JP 2004518704 A5 JP2004518704 A5 JP 2004518704A5
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JP
Japan
Prior art keywords
conjugate
hydrogen
sialyl
compound
lewis
Prior art date
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JP2002563162A
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English (en)
Japanese (ja)
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JP4262480B2 (ja
JP2004518704A (ja
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Priority claimed from PCT/US2001/044590 external-priority patent/WO2002062810A2/en
Publication of JP2004518704A publication Critical patent/JP2004518704A/ja
Publication of JP2004518704A5 publication Critical patent/JP2004518704A5/ja
Application granted granted Critical
Publication of JP4262480B2 publication Critical patent/JP4262480B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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JP2002563162A 2000-11-29 2001-11-29 結合能を有するシアリル・ルイスｘ類似物 Expired - Lifetime JP4262480B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25023800P 2000-11-29 2000-11-29
PCT/US2001/044590 WO2002062810A2 (en) 2000-11-29 2001-11-29 Linkable sialyl lewis x analogs

Publications (3)

Publication Number Publication Date
JP2004518704A JP2004518704A (ja) 2004-06-24
JP2004518704A5 true JP2004518704A5 (https=) 2006-01-12
JP4262480B2 JP4262480B2 (ja) 2009-05-13

Family

ID=22946912

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2002563162A Expired - Lifetime JP4262480B2 (ja) 2000-11-29 2001-11-29 結合能を有するシアリル・ルイスｘ類似物

Country Status (6)

Country Link
US (4) US7422733B2 (https=)
EP (1) EP1337539A2 (https=)
JP (1) JP4262480B2 (https=)
AU (1) AU2002251678A1 (https=)
CA (1) CA2429781C (https=)
WO (1) WO2002062810A2 (https=)

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Publication number Priority date Publication date Assignee Title
US11845771B2 (en) 2018-12-27 2023-12-19 Glycomimetics, Inc. Heterobifunctional inhibitors of E-selectin and galectin-3

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WO2003097658A2 (en) 2002-05-16 2003-11-27 Glycomimetics, Inc. Compounds and methods for inhibiting selectin-mediated function
EP1763533B1 (en) 2003-11-19 2008-01-09 GlycoMimetics, Inc. Specific antagonist for both e- and p-selectins
US7205385B2 (en) * 2004-11-12 2007-04-17 General Electric Company Polymerization method for the synthesis of polypeptide imaging agents
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GB0517077D0 (en) * 2005-08-19 2005-09-28 Isis Innovation Imaging agent
PL2264043T3 (pl) 2005-09-02 2018-04-30 Glycomimetics, Inc. Heterobifunkcyjne inhibitory pan-selektyny
US8926945B2 (en) 2005-10-07 2015-01-06 Guerbet Compounds comprising a biological target recognizing part, coupled to a signal part capable of complexing gallium
US8986650B2 (en) 2005-10-07 2015-03-24 Guerbet Complex folate-NOTA-Ga68
WO2009126556A1 (en) 2008-04-08 2009-10-15 Glycomimetics, Inc. Pan-selectin inhibitor with enhanced pharmacokinetic activity
FR2942227B1 (fr) 2009-02-13 2011-04-15 Guerbet Sa Utilisation de tampons pour la complexation de radionucleides
CA2760292A1 (en) * 2009-05-01 2010-11-04 Glycomimetics, Inc. Heterobifunctional inhibitors of e-selectins and cxcr4 chemokine receptors
US8921328B2 (en) 2010-09-14 2014-12-30 Glycomimetics, Inc. E-selectin antagonists
WO2012061662A1 (en) * 2010-11-03 2012-05-10 Glycomimetics, Inc. Glycomimetic-peptidomimetic inhibitors of e-selectins and cxcr4 chemokine receptors
WO2012060718A1 (en) * 2010-11-05 2012-05-10 Sally Diana Poppitt Preventing or treating metabolic syndrome by administering a trans fatty acid, or a salt, ester or precursor thereof, or sialic acid in free or bound form
FR2968999B1 (fr) 2010-12-20 2013-01-04 Guerbet Sa Nanoemulsion de chelate pour irm
FR2980364B1 (fr) 2011-09-26 2018-08-31 Guerbet Nanoemulsions et leur utilisation comme agents de contraste
KR102055958B1 (ko) 2011-12-22 2019-12-13 글리코미메틱스, 인크. E-셀렉틴 길항제 화합물, 조성물, 및 이용 방법
US9867841B2 (en) 2012-12-07 2018-01-16 Glycomimetics, Inc. Compounds, compositions and methods using E-selectin antagonists for mobilization of hematopoietic cells
FR3001154B1 (fr) 2013-01-23 2015-06-26 Guerbet Sa Magneto-emulsion vectorisee
CN106414472A (zh) * 2013-12-06 2017-02-15 现实制药有限公司 用于靶向癌症和产生抗体的抗神经节苷脂化合物
JP6689854B2 (ja) 2014-12-03 2020-04-28 グリコミメティクス， インコーポレイテッド Ｅ−セレクチンおよびｃｘｃｒ４ケモカイン受容体のヘテロ二官能性阻害剤
EP3170832A1 (en) * 2015-11-17 2017-05-24 Centre National De La Recherche Scientifique Method of preparation of 6-azido-2,4-diacetamido-2,4,6-trideoxy-d-mannose
JP2019502727A (ja) 2016-01-22 2019-01-31 グリコミメティクス， インコーポレイテッド Ｐａ−ｉｌおよび／またはｐａ−ｉｉｌレクチンの糖模倣体阻害剤
WO2017151708A1 (en) 2016-03-02 2017-09-08 Glycomimetics, Inc. Methods for the treatment and/or prevention of cardiovescular disease by inhibition of e-selectin
US11433086B2 (en) 2016-08-08 2022-09-06 Glycomimetics, Inc. Combination of T-cell checkpoint inhibitors with inhibitors of e-selectin or CXCR4, or with heterobifunctional inhibitors of both E-selectin and CXCR4
AU2017341065B2 (en) 2016-10-07 2023-04-06 Crescent Biopharma, Inc. Highly potent multimeric E-selectin antagonists
US11786586B2 (en) 2016-12-23 2023-10-17 Aoa Dx Carbohydrate structures and uses thereof
EP3596096A1 (en) 2017-03-15 2020-01-22 GlycoMimetics, Inc. Galactopyranosyl-cyclohexyl derivatives as e-selectin antagonists
JP7275131B2 (ja) 2017-11-30 2023-05-17 グリコミメティクス， インコーポレイテッド 骨髄浸潤リンパ球を動員する方法、およびその使用
KR20200104889A (ko) 2017-12-29 2020-09-04 글리코미메틱스, 인크. E-셀렉틴 및 갈렉틴-3의 이종이기능성 억제제
KR20200128025A (ko) 2018-03-05 2020-11-11 글리코미메틱스, 인크. 급성 골수성 백혈병 및 관련 병태의 치료 방법
WO2020007822A1 (en) 2018-07-02 2020-01-09 Conservatoire National Des Arts Et Metiers (Cnam) Bismuth metallic (0) nanoparticles, process of manufacturing and uses thereof
US20240361317A1 (en) * 2021-06-22 2024-10-31 Centre National De La Recherche Scientifique Probes based on volatile organic compounds and uses thereof for the diagnosis and prognosis of pathological conditions

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EP0589951A1 (en) * 1991-06-10 1994-04-06 Glycomed Incorporated Modified sialyl lewis?x compounds
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11845771B2 (en) 2018-12-27 2023-12-19 Glycomimetics, Inc. Heterobifunctional inhibitors of E-selectin and galectin-3

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