JP2004518704A5 - - Google Patents

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Publication number
JP2004518704A5
JP2004518704A5 JP2002563162A JP2002563162A JP2004518704A5 JP 2004518704 A5 JP2004518704 A5 JP 2004518704A5 JP 2002563162 A JP2002563162 A JP 2002563162A JP 2002563162 A JP2002563162 A JP 2002563162A JP 2004518704 A5 JP2004518704 A5 JP 2004518704A5
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JP
Japan
Prior art keywords
conjugate
hydrogen
sialyl
compound
lewis
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Granted
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JP2002563162A
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English (en)
Japanese (ja)
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JP4262480B2 (ja
JP2004518704A (ja
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Priority claimed from PCT/US2001/044590 external-priority patent/WO2002062810A2/en
Publication of JP2004518704A publication Critical patent/JP2004518704A/ja
Publication of JP2004518704A5 publication Critical patent/JP2004518704A5/ja
Application granted granted Critical
Publication of JP4262480B2 publication Critical patent/JP4262480B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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JP2002563162A 2000-11-29 2001-11-29 結合能を有するシアリル・ルイスｘ類似物 Expired - Lifetime JP4262480B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25023800P 2000-11-29 2000-11-29
PCT/US2001/044590 WO2002062810A2 (en) 2000-11-29 2001-11-29 Linkable sialyl lewis x analogs

Publications (3)

Publication Number Publication Date
JP2004518704A JP2004518704A (ja) 2004-06-24
JP2004518704A5 true JP2004518704A5 (https=) 2006-01-12
JP4262480B2 JP4262480B2 (ja) 2009-05-13

Family

ID=22946912

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2002563162A Expired - Lifetime JP4262480B2 (ja) 2000-11-29 2001-11-29 結合能を有するシアリル・ルイスｘ類似物

Country Status (6)

Country Link
US (4) US7422733B2 (https=)
EP (1) EP1337539A2 (https=)
JP (1) JP4262480B2 (https=)
AU (1) AU2002251678A1 (https=)
CA (1) CA2429781C (https=)
WO (1) WO2002062810A2 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11845771B2 (en) 2018-12-27 2023-12-19 Glycomimetics, Inc. Heterobifunctional inhibitors of E-selectin and galectin-3

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JP5183010B2 (ja) 2002-05-16 2013-04-17 グリコミメティクス， インコーポレイテッド セレクチンによって媒介される機能を阻害するための化合物および方法
WO2005051920A2 (en) 2003-11-19 2005-06-09 Glycomimetics, Inc. Specific antagonist for both e- and p-selectins
US7205385B2 (en) * 2004-11-12 2007-04-17 General Electric Company Polymerization method for the synthesis of polypeptide imaging agents
EP1928892B1 (en) 2005-08-09 2011-10-12 GlycoMimetics, Inc. Glycomimetic inhibitors of the pa-il lectin, pa-iil lectin or both the lectins from pseudomonas
GB0517077D0 (en) * 2005-08-19 2005-09-28 Isis Innovation Imaging agent
SI2264043T1 (en) 2005-09-02 2018-01-31 Glycomimetics, Inc. HETEROBIFUNCTIONAL PAN-SELECTINE INHIBITORS
US8986650B2 (en) 2005-10-07 2015-03-24 Guerbet Complex folate-NOTA-Ga68
EP1940841B9 (fr) 2005-10-07 2017-04-19 Guerbet Composes comprenant une partie de reconnaissance d'une cible biologique, couplee a une partie de signal capable de complexer le gallium
WO2009126556A1 (en) 2008-04-08 2009-10-15 Glycomimetics, Inc. Pan-selectin inhibitor with enhanced pharmacokinetic activity
FR2942227B1 (fr) 2009-02-13 2011-04-15 Guerbet Sa Utilisation de tampons pour la complexation de radionucleides
WO2010126888A1 (en) * 2009-05-01 2010-11-04 Glycomimetics, Inc. Heterobifunctional inhibitors of e-selectins and cxcr4 chemokine receptors
US8921328B2 (en) 2010-09-14 2014-12-30 Glycomimetics, Inc. E-selectin antagonists
WO2012061662A1 (en) * 2010-11-03 2012-05-10 Glycomimetics, Inc. Glycomimetic-peptidomimetic inhibitors of e-selectins and cxcr4 chemokine receptors
WO2012060718A1 (en) * 2010-11-05 2012-05-10 Sally Diana Poppitt Preventing or treating metabolic syndrome by administering a trans fatty acid, or a salt, ester or precursor thereof, or sialic acid in free or bound form
FR2968999B1 (fr) 2010-12-20 2013-01-04 Guerbet Sa Nanoemulsion de chelate pour irm
FR2980364B1 (fr) 2011-09-26 2018-08-31 Guerbet Nanoemulsions et leur utilisation comme agents de contraste
PT2794626T (pt) 2011-12-22 2018-01-12 Glycomimetics Inc Compostos de antagonistas de e-selectina
CA2891514C (en) 2012-12-07 2020-08-25 Glycomimetics, Inc. Compounds, compositions and methods using e-selectin antagonists for mobilization of hematopoietic cells
FR3001154B1 (fr) 2013-01-23 2015-06-26 Guerbet Sa Magneto-emulsion vectorisee
ES2904533T3 (es) 2013-12-06 2022-04-05 Aoa Dx Compuesto antigangliósido para dirigirlo contra el cáncer y generar anticuerpos
ES2754549T3 (es) 2014-12-03 2020-04-20 Glycomimetics Inc Inhibidores heterobifuncionales de E-selectinas y receptores de quimioquinas CXCR4
EP3170832A1 (en) 2015-11-17 2017-05-24 Centre National De La Recherche Scientifique Method of preparation of 6-azido-2,4-diacetamido-2,4,6-trideoxy-d-mannose
JP2019502727A (ja) 2016-01-22 2019-01-31 グリコミメティクス， インコーポレイテッド Ｐａ−ｉｌおよび／またはｐａ−ｉｉｌレクチンの糖模倣体阻害剤
WO2017151708A1 (en) 2016-03-02 2017-09-08 Glycomimetics, Inc. Methods for the treatment and/or prevention of cardiovescular disease by inhibition of e-selectin
EP3497131B1 (en) 2016-08-08 2022-03-09 GlycoMimetics, Inc. Combination of t-cell checkpoint inhibitors with inhibitors of e-selectin or cxcr4, or with heterobifunctional inhibitors of both e-selectin and cxcr4.
US11072625B2 (en) 2016-10-07 2021-07-27 Glycomimetics, Inc. Highly potent multimeric e-selectin antagonists
WO2018112669A1 (en) 2016-12-23 2018-06-28 Realist Pharma, Inc. Ganglioside carbohydrate structures and uses thereof
CA3054605A1 (en) 2017-03-15 2018-09-20 Glycomimetics, Inc. Galactopyranosyl-cyclohexyl derivatives as e-selectin antagonists
WO2019108750A1 (en) 2017-11-30 2019-06-06 Glycomimetics, Inc. Methods of mobilizing marrow infiltrating lymphocytes and uses thereof
CN111566117A (zh) 2017-12-29 2020-08-21 糖模拟物有限公司 E-选择蛋白和半乳凝素-3的异双功能抑制剂
WO2019173229A1 (en) 2018-03-05 2019-09-12 Glycomimetics, Inc. Methods for treating acute myeloid leukemia and related conditions
WO2020007822A1 (en) 2018-07-02 2020-01-09 Conservatoire National Des Arts Et Metiers (Cnam) Bismuth metallic (0) nanoparticles, process of manufacturing and uses thereof
CA3223246A1 (fr) * 2021-06-22 2022-12-29 Pauline Poinot Sondes a base de composes organiques volatils et leurs utilisations pour le diagnostic et le pronostic de pathologies

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WO1992022563A1 (en) 1991-06-10 1992-12-23 Alberta Research Council Modified sialyl lewisa compounds
EP0589951A1 (en) 1991-06-10 1994-04-06 Glycomed Incorporated Modified sialyl lewis?x compounds
GB9309513D0 (en) 1993-05-08 1993-06-23 Univ Coventry Electrochemical method of modifying biomolecules in particular proteins
RO117533B1 (ro) * 1993-05-14 2002-04-30 Cytel Corp San Diego DERIVATI DE ANALOGI SIALIL LeX INHIBITORI AI ADEZIUNII CELULARE SI COMPOZITIE FARMACEUTICA CU ACESTIA
US5608110A (en) * 1993-06-15 1997-03-04 Bracco International B.V. Heteroatom-bearing ligands and metal complexes thereof
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11845771B2 (en) 2018-12-27 2023-12-19 Glycomimetics, Inc. Heterobifunctional inhibitors of E-selectin and galectin-3

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