JP2004518704A5 - - Google Patents

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Publication number
JP2004518704A5
JP2004518704A5 JP2002563162A JP2002563162A JP2004518704A5 JP 2004518704 A5 JP2004518704 A5 JP 2004518704A5 JP 2002563162 A JP2002563162 A JP 2002563162A JP 2002563162 A JP2002563162 A JP 2002563162A JP 2004518704 A5 JP2004518704 A5 JP 2004518704A5
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JP
Japan
Prior art keywords
conjugate
hydrogen
sialyl
compound
lewis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2002563162A
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English (en)
Japanese (ja)
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JP4262480B2 (ja
JP2004518704A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2001/044590 external-priority patent/WO2002062810A2/en
Publication of JP2004518704A publication Critical patent/JP2004518704A/ja
Publication of JP2004518704A5 publication Critical patent/JP2004518704A5/ja
Application granted granted Critical
Publication of JP4262480B2 publication Critical patent/JP4262480B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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JP2002563162A 2000-11-29 2001-11-29 結合能を有するシアリル・ルイスｘ類似物 Expired - Lifetime JP4262480B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25023800P 2000-11-29 2000-11-29
PCT/US2001/044590 WO2002062810A2 (en) 2000-11-29 2001-11-29 Linkable sialyl lewis x analogs

Publications (3)

Publication Number Publication Date
JP2004518704A JP2004518704A (ja) 2004-06-24
JP2004518704A5 true JP2004518704A5 (enExample) 2006-01-12
JP4262480B2 JP4262480B2 (ja) 2009-05-13

Family

ID=22946912

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2002563162A Expired - Lifetime JP4262480B2 (ja) 2000-11-29 2001-11-29 結合能を有するシアリル・ルイスｘ類似物

Country Status (6)

Country Link
US (4) US7422733B2 (enExample)
EP (1) EP1337539A2 (enExample)
JP (1) JP4262480B2 (enExample)
AU (1) AU2002251678A1 (enExample)
CA (1) CA2429781C (enExample)
WO (1) WO2002062810A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11845771B2 (en) 2018-12-27 2023-12-19 Glycomimetics, Inc. Heterobifunctional inhibitors of E-selectin and galectin-3

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JP5183010B2 (ja) 2002-05-16 2013-04-17 グリコミメティクス， インコーポレイテッド セレクチンによって媒介される機能を阻害するための化合物および方法
DE602004011272T2 (de) 2003-11-19 2008-12-24 Glycomimetics, Inc. Spezifischer antagonist sowohl für e- als auch p-selektine
US7205385B2 (en) * 2004-11-12 2007-04-17 General Electric Company Polymerization method for the synthesis of polypeptide imaging agents
WO2007021721A2 (en) 2005-08-09 2007-02-22 Glycomimetics, Inc. Glycomimetic inhibitors of the pa-il lectin, pa-iil lectin or both the lectins from pseudomonas
GB0517077D0 (en) * 2005-08-19 2005-09-28 Isis Innovation Imaging agent
SI2264043T1 (en) 2005-09-02 2018-01-31 Glycomimetics, Inc. HETEROBIFUNCTIONAL PAN-SELECTINE INHIBITORS
US8926945B2 (en) 2005-10-07 2015-01-06 Guerbet Compounds comprising a biological target recognizing part, coupled to a signal part capable of complexing gallium
US8986650B2 (en) 2005-10-07 2015-03-24 Guerbet Complex folate-NOTA-Ga68
US8895510B2 (en) 2008-04-08 2014-11-25 Glycomimetics, Inc. Pan-selectin inhibitor with enhanced pharmacokinetic activity
FR2942227B1 (fr) 2009-02-13 2011-04-15 Guerbet Sa Utilisation de tampons pour la complexation de radionucleides
AU2010241807B2 (en) * 2009-05-01 2014-08-14 Glycomimetics, Inc. Heterobifunctional inhibitors of E-selectins and CXCR4 chemokine receptors
US8921328B2 (en) 2010-09-14 2014-12-30 Glycomimetics, Inc. E-selectin antagonists
WO2012061662A1 (en) * 2010-11-03 2012-05-10 Glycomimetics, Inc. Glycomimetic-peptidomimetic inhibitors of e-selectins and cxcr4 chemokine receptors
WO2012060718A1 (en) * 2010-11-05 2012-05-10 Sally Diana Poppitt Preventing or treating metabolic syndrome by administering a trans fatty acid, or a salt, ester or precursor thereof, or sialic acid in free or bound form
FR2968999B1 (fr) 2010-12-20 2013-01-04 Guerbet Sa Nanoemulsion de chelate pour irm
FR2980364B1 (fr) 2011-09-26 2018-08-31 Guerbet Nanoemulsions et leur utilisation comme agents de contraste
EP2794626B3 (en) 2011-12-22 2020-08-05 GlycoMimetics, Inc. E-selectin antagonist compounds
HUE038423T2 (hu) 2012-12-07 2018-10-29 Glycomimetics Inc E-szelektin antagonistákat felhasználó vegyületek, készítmények és eljárások vérképzõ sejtek mobilizációjára
FR3001154B1 (fr) 2013-01-23 2015-06-26 Guerbet Sa Magneto-emulsion vectorisee
CN106414472A (zh) * 2013-12-06 2017-02-15 现实制药有限公司 用于靶向癌症和产生抗体的抗神经节苷脂化合物
CN107108679B (zh) 2014-12-03 2020-10-23 糖模拟物有限公司 E-选择蛋白和cxcr4趋化因子受体的异双官能抑制剂
EP3170832A1 (en) * 2015-11-17 2017-05-24 Centre National De La Recherche Scientifique Method of preparation of 6-azido-2,4-diacetamido-2,4,6-trideoxy-d-mannose
WO2017127422A1 (en) 2016-01-22 2017-07-27 Glycomimetics, Inc. Glycomimetic inhibitors of pa-il and pa-iil lectins
US11291678B2 (en) 2016-03-02 2022-04-05 Glycomimetics, Inc Methods for the treatment and/or prevention of cardiovascular disease by inhibition of E-selectin
US11433086B2 (en) 2016-08-08 2022-09-06 Glycomimetics, Inc. Combination of T-cell checkpoint inhibitors with inhibitors of e-selectin or CXCR4, or with heterobifunctional inhibitors of both E-selectin and CXCR4
BR112019006642A2 (pt) 2016-10-07 2019-07-02 Glycomimetics Inc antagonistas multiméricos de e-selectina altamente potentes
US11786586B2 (en) 2016-12-23 2023-10-17 Aoa Dx Carbohydrate structures and uses thereof
CA3054605A1 (en) 2017-03-15 2018-09-20 Glycomimetics, Inc. Galactopyranosyl-cyclohexyl derivatives as e-selectin antagonists
EP3717013A1 (en) 2017-11-30 2020-10-07 GlycoMimetics, Inc. Methods of mobilizing marrow infiltrating lymphocytes and uses thereof
US11548908B2 (en) 2017-12-29 2023-01-10 Glycomimetics, Inc. Heterobifunctional inhibitors of E-selectin and galectin-3
AU2019230013A1 (en) 2018-03-05 2020-09-10 Glycomimetics, Inc. Methods for treating acute myeloid leukemia and related conditions
WO2020007822A1 (en) 2018-07-02 2020-01-09 Conservatoire National Des Arts Et Metiers (Cnam) Bismuth metallic (0) nanoparticles, process of manufacturing and uses thereof
CA3223246A1 (fr) * 2021-06-22 2022-12-29 Pauline Poinot Sondes a base de composes organiques volatils et leurs utilisations pour le diagnostic et le pronostic de pathologies

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CA1260393A (en) * 1984-10-16 1989-09-26 Lajos Tarcsay Liposomes of synthetic lipids
US5776093A (en) * 1985-07-05 1998-07-07 Immunomedics, Inc. Method for imaging and treating organs and tissues
MX174467B (es) * 1986-01-23 1994-05-17 Squibb & Sons Inc 1,4,7-triscarboximetil-1,4,7,10-tetraazaciclodo decano substituido en 1 y compuestos analogos
JPH06510745A (ja) 1991-06-10 1994-12-01 グライカムド　インコーポレイテッド 修飾シアリルルイスａ化合物
EP0589951A1 (en) * 1991-06-10 1994-04-06 Glycomed Incorporated Modified sialyl lewis?x compounds
GB9309513D0 (en) 1993-05-08 1993-06-23 Univ Coventry Electrochemical method of modifying biomolecules in particular proteins
CN1125449A (zh) * 1993-05-14 1996-06-26 萨依特尔有限公司 作为细胞粘附抑制剂的唾液基Lex类似物
US5608110A (en) * 1993-06-15 1997-03-04 Bracco International B.V. Heteroatom-bearing ligands and metal complexes thereof
US5662885A (en) * 1994-07-22 1997-09-02 Resolution Pharmaceuticals Inc. Peptide derived radionuclide chelators
US6132764A (en) * 1994-08-05 2000-10-17 Targesome, Inc. Targeted polymerized liposome diagnostic and treatment agents
US6331289B1 (en) * 1996-10-28 2001-12-18 Nycomed Imaging As Targeted diagnostic/therapeutic agents having more than one different vectors

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11845771B2 (en) 2018-12-27 2023-12-19 Glycomimetics, Inc. Heterobifunctional inhibitors of E-selectin and galectin-3

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