JP2004518631A - 異種核酸の送達のための微粒子 - Google Patents

異種核酸の送達のための微粒子 Download PDF

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JP2004518631A
JP2004518631A JP2002530039A JP2002530039A JP2004518631A JP 2004518631 A JP2004518631 A JP 2004518631A JP 2002530039 A JP2002530039 A JP 2002530039A JP 2002530039 A JP2002530039 A JP 2002530039A JP 2004518631 A JP2004518631 A JP 2004518631A
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microparticle
antigen
microparticles
hiv
seq
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JP2004518631A5 (https=
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デレック オハガン，
ジリス オッテン，
ジョン ジェイムス ドネリー，
ジョン エム． ポロ，
スーザン バーネット，
マンモハン シン，
ジェフリー ウルマー，
トーマス ダブリュー． ジュニア ダベンスキー，
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カイロン コーポレイション
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    • C12N15/09—Recombinant DNA-technology
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    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
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    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
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    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
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    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
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    • A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6093—Synthetic polymers, e.g. polyethyleneglycol [PEG], Polymers or copolymers of (D) glutamate and (D) lysine
    • C—CHEMISTRY; METALLURGY
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    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16211—Human Immunodeficiency Virus, HIV concerning HIV gagpol
    • C12N2740/16234—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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    • C12N2770/36141—Use of virus, viral particle or viral elements as a vector
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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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JP2002530039A 2000-09-28 2001-09-28 異種核酸の送達のための微粒子 Pending JP2004518631A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US23610500P 2000-09-28 2000-09-28
US31590501P 2001-08-30 2001-08-30
PCT/US2001/030540 WO2002026209A2 (en) 2000-09-28 2001-09-28 Microparticles for delivery of the heterologous nucleic acids

Publications (2)

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JP2004518631A true JP2004518631A (ja) 2004-06-24
JP2004518631A5 JP2004518631A5 (https=) 2008-11-13

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JP2002530039A Pending JP2004518631A (ja) 2000-09-28 2001-09-28 異種核酸の送達のための微粒子

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US (2) US20030138453A1 (https=)
EP (1) EP1322287B1 (https=)
JP (1) JP2004518631A (https=)
CN (1) CN1468089B (https=)
AT (1) ATE320792T1 (https=)
AU (1) AU9489701A (https=)
BR (1) BR0114305A (https=)
CA (1) CA2421683C (https=)
DE (1) DE60118228T2 (https=)
DK (1) DK1322287T3 (https=)
ES (1) ES2260291T3 (https=)
MX (1) MXPA03002640A (https=)
PT (1) PT1322287E (https=)
SG (1) SG137691A1 (https=)
WO (1) WO2002026209A2 (https=)
ZA (1) ZA200301744B (https=)

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JP2009515859A (ja) * 2005-11-14 2009-04-16 サントル ナシオナル ドゥ ラ ルシェルシェサイアンティフィク（セエヌエールエス） コロイド性合成生体吸収性ベクターとウイルスベクターを含む組成物

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