JP2004514423A - トランスジェニックｘｅｎｏｍｏｕｓｅ（登録商標）から獲得されるｐｅｕｄｏｍｏｎａｓａｅｒｕｇｉｎｏｓａｌｐｓに対するヒト抗体 - Google Patents

トランスジェニックｘｅｎｏｍｏｕｓｅ（登録商標）から獲得されるｐｅｕｄｏｍｏｎａｓａｅｒｕｇｉｎｏｓａｌｐｓに対するヒト抗体 Download PDF

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JP2004514423A
JP2004514423A JP2002525238A JP2002525238A JP2004514423A JP 2004514423 A JP2004514423 A JP 2004514423A JP 2002525238 A JP2002525238 A JP 2002525238A JP 2002525238 A JP2002525238 A JP 2002525238A JP 2004514423 A JP2004514423 A JP 2004514423A
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antibody
antigen
binding portion
isolated
human
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シュライバー，　ジョン　アール．
カンボジュ，　クルワント　カウアー
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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    • A—HUMAN NECESSITIES
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    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
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    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203—Gram-negative bacteria
    • C07K16/1214—Pseudomonadaceae (F)
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
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    • C07—ORGANIC CHEMISTRY
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    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man

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JP2002525238A 2000-09-07 2001-09-07 トランスジェニックｘｅｎｏｍｏｕｓｅ（登録商標）から獲得されるｐｅｕｄｏｍｏｎａｓａｅｒｕｇｉｎｏｓａｌｐｓに対するヒト抗体 Pending JP2004514423A (ja)

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US23064000P 2000-09-07 2000-09-07
US25947201P 2001-01-03 2001-01-03
PCT/US2001/028019 WO2002020619A2 (en) 2000-09-07 2001-09-07 HUMAN ANTIBODIES AGAINST PSEUDOMONAS AERUGINOSA LPS DERIVED FROM TRANSGENIC XENOMOUSE$m(3)

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JP2004514423A true JP2004514423A (ja) 2004-05-20
JP2004514423A5 JP2004514423A5 (https=) 2008-10-23

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US (3) US7972845B2 (https=)
EP (1) EP1319025A2 (https=)
JP (1) JP2004514423A (https=)
AU (1) AU8886601A (https=)
CA (1) CA2422204A1 (https=)
WO (1) WO2002020619A2 (https=)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013079240A (ja) * 2004-12-08 2013-05-02 Immunomedics Inc 炎症性疾患および免疫調節不全疾患、感染性疾患、病的血管新生およびがんの免疫療法および検出のための方法および組成物
JP2015537034A (ja) * 2012-11-21 2015-12-24 ウーハン ワイゼットワイ バイオファルマ カンパニー リミテッドＷｕｈａｎ Ｙｚｙ Ｂｉｏｐｈａｒｍａ Ｃｏ．， Ｌｔｄ． 二重特異性抗体
JP2019505220A (ja) * 2015-11-10 2019-02-28 ビステラ， インコーポレイテッド リポ多糖に特異的に結合する抗体分子−薬物コンジュゲートおよびその使用
JP2020506685A (ja) * 2017-01-18 2020-03-05 ビステラ， インコーポレイテッド 抗体分子−薬物コンジュゲートおよびその使用
US11969476B2 (en) 2020-04-03 2024-04-30 Visterra, Inc. Antibody molecule-drug conjugates and uses thereof

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004514423A (ja) 2000-09-07 2004-05-20 シュライバー，　ジョン　アール． トランスジェニックｘｅｎｏｍｏｕｓｅ（登録商標）から獲得されるｐｅｕｄｏｍｏｎａｓａｅｒｕｇｉｎｏｓａｌｐｓに対するヒト抗体
EP1479695B1 (en) * 2003-05-14 2010-02-17 Kenta Biotech AG Human monoclonal antibody specific for lipopolysaccharides (LPS) of serotype IATS O6 of Pseudomonas aeruginosa
EP1706425A2 (en) 2003-12-05 2006-10-04 John R. Schreiber Human anti-pseudomonas-aeruginosa antibodies derived from transgenic xenomouse®
US8821884B2 (en) * 2004-07-27 2014-09-02 The Regents Of The University Of California Compositions and methods using MD-2 mutants and chimeric proteins
EP1690875A1 (en) * 2005-02-14 2006-08-16 Kenta Biotech AG Human monoclonal antibody specific for lipopolysaccharides (LPS) of the pseudomonas aeruginosa IATS O11 serotype
IL292311A (en) 2014-04-03 2022-06-01 Igm Biosciences Inc J-chain qualified
EP3824903A1 (en) 2015-09-30 2021-05-26 IGM Biosciences Inc. Binding molecules with modified j-chain
EP3356401B1 (en) 2015-09-30 2020-06-24 IGM Biosciences, Inc. Binding molecules with modified j-chain

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JP2004514423A (ja) 2000-09-07 2004-05-20 シュライバー，　ジョン　アール． トランスジェニックｘｅｎｏｍｏｕｓｅ（登録商標）から獲得されるｐｅｕｄｏｍｏｎａｓａｅｒｕｇｉｎｏｓａｌｐｓに対するヒト抗体
AR039067A1 (es) 2001-11-09 2005-02-09 Pfizer Prod Inc Anticuerpos para cd40
AU2002351208A1 (en) 2001-12-03 2003-06-17 Abgenix, Inc. Antibodies against carbonic anhydrase IX (CA IX) tumor antigen

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JPN6014033899; Ｔｈｅ　Ｊｏｕｒｎａｌ　ｏｆ　Ｉｎｆｅｃｔｉｏｕｓ　Ｄｉｓｅａｓｅｓ Ｖｏｌ．１５５，　Ｎｏ．６, 1987, ｐ．１２８２-１２９１

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013079240A (ja) * 2004-12-08 2013-05-02 Immunomedics Inc 炎症性疾患および免疫調節不全疾患、感染性疾患、病的血管新生およびがんの免疫療法および検出のための方法および組成物
JP2015537034A (ja) * 2012-11-21 2015-12-24 ウーハン ワイゼットワイ バイオファルマ カンパニー リミテッドＷｕｈａｎ Ｙｚｙ Ｂｉｏｐｈａｒｍａ Ｃｏ．， Ｌｔｄ． 二重特異性抗体
JP2019505220A (ja) * 2015-11-10 2019-02-28 ビステラ， インコーポレイテッド リポ多糖に特異的に結合する抗体分子−薬物コンジュゲートおよびその使用
US11168131B2 (en) 2015-11-10 2021-11-09 Visterra, Inc. Antibody molecule-drug conjugates and uses thereof
JP7041628B2 (ja) 2015-11-10 2022-03-24 ビステラ， インコーポレイテッド リポ多糖に特異的に結合する抗体分子－薬物コンジュゲートおよびその使用
JP2020506685A (ja) * 2017-01-18 2020-03-05 ビステラ， インコーポレイテッド 抗体分子−薬物コンジュゲートおよびその使用
JP7303110B2 (ja) 2017-01-18 2023-07-04 ビステラ， インコーポレイテッド 抗体分子－薬物コンジュゲートおよびその使用
US11890319B2 (en) 2017-01-18 2024-02-06 Visterra, Inc. Antibody molecule-drug conjugates and uses thereof
US11969476B2 (en) 2020-04-03 2024-04-30 Visterra, Inc. Antibody molecule-drug conjugates and uses thereof

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AU8886601A (en) 2002-03-22
CA2422204A1 (en) 2002-03-14
US20130156696A1 (en) 2013-06-20
US8986990B2 (en) 2015-03-24
WO2002020619A2 (en) 2002-03-14
WO2002020619A9 (en) 2003-04-17
US20150175680A1 (en) 2015-06-25
WO2002020619A3 (en) 2003-01-23
US20040137001A1 (en) 2004-07-15
US9089557B2 (en) 2015-07-28
US7972845B2 (en) 2011-07-05
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