JP2004509858A5 - - Google Patents

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Publication number
JP2004509858A5
JP2004509858A5 JP2002516054A JP2002516054A JP2004509858A5 JP 2004509858 A5 JP2004509858 A5 JP 2004509858A5 JP 2002516054 A JP2002516054 A JP 2002516054A JP 2002516054 A JP2002516054 A JP 2002516054A JP 2004509858 A5 JP2004509858 A5 JP 2004509858A5
Authority
JP
Japan
Prior art keywords
antibody
prp
ungulate
natural
binding affinity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2002516054A
Other languages
English (en)
Japanese (ja)
Other versions
JP2004509858A (ja
Filing date
Publication date
Priority claimed from US09/627,218 external-priority patent/US6537548B1/en
Application filed filed Critical
Publication of JP2004509858A publication Critical patent/JP2004509858A/ja
Publication of JP2004509858A5 publication Critical patent/JP2004509858A5/ja
Pending legal-status Critical Current

Links

JP2002516054A 2000-07-27 2001-07-17 有蹄類PrPに特異的な抗体 Pending JP2004509858A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/627,218 US6537548B1 (en) 2000-07-27 2000-07-27 Antibodies specific for ungulate PrP
PCT/US2001/022648 WO2002010335A2 (en) 2000-07-27 2001-07-17 ANTIBODIES SPECIFIC FOR UNGULATE PrP

Publications (2)

Publication Number Publication Date
JP2004509858A JP2004509858A (ja) 2004-04-02
JP2004509858A5 true JP2004509858A5 (https=) 2005-08-25

Family

ID=24513726

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2002516054A Pending JP2004509858A (ja) 2000-07-27 2001-07-17 有蹄類PrPに特異的な抗体

Country Status (6)

Country Link
US (3) US6537548B1 (https=)
EP (1) EP1368644A2 (https=)
JP (1) JP2004509858A (https=)
AU (2) AU7597701A (https=)
CA (1) CA2416029A1 (https=)
WO (1) WO2002010335A2 (https=)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ536054A (en) * 2002-04-09 2009-10-30 Scripps Research Inst Motif-grafted hybrid polypeptides and uses thereof
US20060035242A1 (en) 2004-08-13 2006-02-16 Michelitsch Melissa D Prion-specific peptide reagents
GB0402123D0 (en) * 2004-01-30 2004-03-03 Protherics Plc Method
US20050256425A1 (en) 2004-05-11 2005-11-17 Inpro Biotechnology, Inc. Device, system and method for extracting and preparing brain tissue
WO2006076683A2 (en) * 2005-01-13 2006-07-20 Novartis Vaccines And Diagnostics Inc. Isolation and detection of pathogenic prions
MX2007008497A (es) * 2005-01-13 2007-09-14 Novartis Vaccines & Diagnostic Ensayos inmunosorbentes enlazados a enzimas usando reactivos de peptidos especificos de prion.
WO2006102099A2 (en) * 2005-03-18 2006-09-28 The Regents Of The University Of California ANTIBODIES SPECIFIC FOR HUMAN AND BOVINE PrP
KR20080048527A (ko) 2005-09-09 2008-06-02 노파르티스 아게 프리온-특이적 펩토이드 시약
CA2721982A1 (en) * 2008-04-30 2009-11-05 Novartis Ag Assay for pathogenic conformers
US10391068B2 (en) 2012-08-06 2019-08-27 Trustees Of Boston University Prion protein ligands as therapeutic agents for neurodegenerative disorders

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL246462A (https=) * 1959-08-06
US4806627A (en) 1987-05-29 1989-02-21 Research Foundation Of Mental Hygiene Inc. Hybrid cell lines producing monoclonal antibodies dircted against scrapie-associated fibril proteins
US5792901A (en) 1994-05-13 1998-08-11 The Regents Of The University Of California Detecting prions in a sample and prion preparation and transgenic animal used for same
US5908969A (en) 1994-05-13 1999-06-01 The Regents Of The University Of California Method of detecting prions in a sample and transgenic animal used for same
DE852011T1 (de) 1995-09-14 2001-10-11 Scripps Res Inst La Jolla Für natives prp-sc spezifische antikörper
US5891641A (en) 1997-02-21 1999-04-06 The Regents Of The University Of California Assay for disease related conformation of a protein
DE1057022T1 (de) * 1998-02-20 2001-10-25 The Regents Of The University Of California, Oakland Assay für spezifische stämme von mit mehreren krankheiten zusammenhängenden proteinkonformationen
US6528269B1 (en) 1998-06-22 2003-03-04 Case Western Reserve University Immunological agents specific for prion protein (PRP)
US6261790B1 (en) 1999-07-15 2001-07-17 The United States Of America As Represented By The Secretary Of Agriculture Monoclonal antibodies and antibody cocktail for detection of prion protein as an indication of transmissible spongiform encephalopathies
WO2001007479A2 (en) 1999-07-27 2001-02-01 Imperial College Innovations Limited Fragments of cellular prion protein and methods useful in the diagnosis and treatment of prion diseases

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