JP2004506482A5 - - Google Patents
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- JP2004506482A5 JP2004506482A5 JP2002520746A JP2002520746A JP2004506482A5 JP 2004506482 A5 JP2004506482 A5 JP 2004506482A5 JP 2002520746 A JP2002520746 A JP 2002520746A JP 2002520746 A JP2002520746 A JP 2002520746A JP 2004506482 A5 JP2004506482 A5 JP 2004506482A5
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- JP
- Japan
- Prior art keywords
- support structure
- composition
- days
- constructed
- acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 description 29
- 239000000463 material Substances 0.000 description 12
- 239000002253 acid Substances 0.000 description 8
- 230000001150 spermicidal effect Effects 0.000 description 7
- 238000013268 sustained release Methods 0.000 description 7
- 239000012730 sustained-release form Substances 0.000 description 7
- 210000001215 vagina Anatomy 0.000 description 7
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 6
- 239000004222 ferrous gluconate Substances 0.000 description 4
- 235000013924 ferrous gluconate Nutrition 0.000 description 4
- 229960001645 ferrous gluconate Drugs 0.000 description 4
- 230000002401 inhibitory effect Effects 0.000 description 4
- 238000003780 insertion Methods 0.000 description 4
- 230000037431 insertion Effects 0.000 description 4
- VRIVJOXICYMTAG-IYEMJOQQSA-L iron(ii) gluconate Chemical compound [Fe+2].OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O VRIVJOXICYMTAG-IYEMJOQQSA-L 0.000 description 4
- 235000010323 ascorbic acid Nutrition 0.000 description 3
- 229960005070 ascorbic acid Drugs 0.000 description 3
- 239000011668 ascorbic acid Substances 0.000 description 3
- 229920000249 biocompatible polymer Polymers 0.000 description 3
- 229920002988 biodegradable polymer Polymers 0.000 description 3
- 239000004621 biodegradable polymer Substances 0.000 description 3
- 239000003433 contraceptive agent Substances 0.000 description 3
- 230000002254 contraceptive effect Effects 0.000 description 3
- 238000004090 dissolution Methods 0.000 description 3
- 239000000017 hydrogel Substances 0.000 description 3
- 229920000642 polymer Polymers 0.000 description 3
- AEMRFAOFKBGASW-UHFFFAOYSA-N Glycolic acid Polymers OCC(O)=O AEMRFAOFKBGASW-UHFFFAOYSA-N 0.000 description 2
- TWRXJAOTZQYOKJ-UHFFFAOYSA-L Magnesium chloride Chemical compound [Mg+2].[Cl-].[Cl-] TWRXJAOTZQYOKJ-UHFFFAOYSA-L 0.000 description 2
- 229920001244 Poly(D,L-lactide) Polymers 0.000 description 2
- 229920000954 Polyglycolide Polymers 0.000 description 2
- 210000003756 cervix mucus Anatomy 0.000 description 2
- 229920000747 poly(lactic acid) Polymers 0.000 description 2
- 210000000582 semen Anatomy 0.000 description 2
- UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 description 1
- 241000124008 Mammalia Species 0.000 description 1
- 239000001110 calcium chloride Substances 0.000 description 1
- 229910001628 calcium chloride Inorganic materials 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 229920001577 copolymer Polymers 0.000 description 1
- 229910000365 copper sulfate Inorganic materials 0.000 description 1
- ARUVKPQLZAKDPS-UHFFFAOYSA-L copper(II) sulfate Chemical compound [Cu+2].[O-][S+2]([O-])([O-])[O-] ARUVKPQLZAKDPS-UHFFFAOYSA-L 0.000 description 1
- 239000011790 ferrous sulphate Substances 0.000 description 1
- 235000003891 ferrous sulphate Nutrition 0.000 description 1
- 230000003054 hormonal effect Effects 0.000 description 1
- BAUYGSIQEAFULO-UHFFFAOYSA-L iron(2+) sulfate (anhydrous) Chemical compound [Fe+2].[O-]S([O-])(=O)=O BAUYGSIQEAFULO-UHFFFAOYSA-L 0.000 description 1
- 229910000359 iron(II) sulfate Inorganic materials 0.000 description 1
- 229910001629 magnesium chloride Inorganic materials 0.000 description 1
- 239000011976 maleic acid Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 150000007524 organic acids Chemical class 0.000 description 1
- 230000001568 sexual effect Effects 0.000 description 1
- 239000000934 spermatocidal agent Substances 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22774000P | 2000-08-24 | 2000-08-24 | |
| PCT/US2001/026475 WO2002015832A1 (en) | 2000-08-24 | 2001-08-24 | Non-hormonal vaginal contraceptive |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004506482A JP2004506482A (ja) | 2004-03-04 |
| JP2004506482A5 true JP2004506482A5 (enExample) | 2008-10-30 |
Family
ID=22854264
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002520746A Pending JP2004506482A (ja) | 2000-08-24 | 2001-08-24 | 非ホルモン性腟内避妊用具 |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US7521064B2 (enExample) |
| EP (1) | EP1313422B1 (enExample) |
| JP (1) | JP2004506482A (enExample) |
| AT (1) | ATE455526T1 (enExample) |
| AU (2) | AU2001286726B2 (enExample) |
| CA (1) | CA2420348C (enExample) |
| DE (1) | DE60141145D1 (enExample) |
| WO (1) | WO2002015832A1 (enExample) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE60141145D1 (enExample) * | 2000-08-24 | 2010-03-11 | Sidney Lerner | |
| US8404272B2 (en) * | 2003-06-26 | 2013-03-26 | Poly-Med, Inc. | Fiber-reinforced composite rings for intravaginal controlled drug delivery |
| US8399013B2 (en) | 2003-06-26 | 2013-03-19 | Poly-Med, Inc. | Partially absorbable fiber-reinforced composites for controlled drug delivery |
| US20060240071A1 (en) * | 2003-07-31 | 2006-10-26 | Sidney Lerner | Non-hormonal vaginal contraceptive |
| WO2006065873A2 (en) * | 2004-12-14 | 2006-06-22 | Poly-Med, Inc. | Intravaginal ringed mesh device and applicator therefor |
| EP1933810B1 (en) * | 2005-08-11 | 2012-10-10 | Massachusetts Institute of Technology | Intravesical drug delivery device and method |
| KR101451991B1 (ko) | 2005-10-18 | 2014-10-22 | 스타파마 피티와이 리미티드 | 살미생물성 덴드리머 조성물 전달 시스템 |
| US8399012B2 (en) * | 2006-04-17 | 2013-03-19 | Kimberly-Clark Worldwide, Inc. | Degradable therapeutic delivery device |
| US8177706B2 (en) * | 2006-07-10 | 2012-05-15 | Mcneil-Ppc, Inc. | Method of treating urinary incontinence |
| EP3009477B1 (en) | 2006-07-20 | 2024-01-24 | Orbusneich Medical Pte. Ltd | Bioabsorbable polymeric composition for a medical device |
| US8691321B2 (en) | 2006-10-20 | 2014-04-08 | Orbusneich Medical, Inc. | Bioabsorbable polymeric composition and medical device background |
| US7959942B2 (en) | 2006-10-20 | 2011-06-14 | Orbusneich Medical, Inc. | Bioabsorbable medical device with coating |
| JP5560200B2 (ja) | 2007-12-11 | 2014-07-23 | マサチューセッツ インスチテュート オブ テクノロジー | 膀胱および他の身体の小嚢又は管腔を治療するための埋め込み型薬物供給デバイス |
| US9034365B2 (en) | 2008-05-20 | 2015-05-19 | Poly-Med, Inc. | Biostable, multipurpose, microbicidal intravaginal devices |
| CN102176931B (zh) * | 2008-08-09 | 2015-03-04 | 麻省理工学院 | 治疗男性泌尿生殖组织和外周组织的可植入药物递送设备和方法 |
| ES2401008T3 (es) | 2009-06-26 | 2013-04-16 | Taris Biomedical, Inc. | Comprimidos farmacéuticos sólidos para dispositivos implantables para la administración de fármacos |
| US9017312B2 (en) | 2009-09-10 | 2015-04-28 | Taris Biomedical Llc | Implantable device for controlled drug delivery |
| JP5864429B2 (ja) | 2009-11-09 | 2016-02-17 | スポットライト テクノロジー パートナーズ エルエルシーＳｐｏｔｌｉｇｈｔ Ｔｅｃｈｎｏｌｏｇｙ Ｐａｒｔｎｅｒｓ Ｌｌｃ | 架橋ヒドロゲル組成物、ヒドロゲル組成物の形成方法、及びキット |
| JP2013509963A (ja) | 2009-11-09 | 2013-03-21 | スポットライト テクノロジー パートナーズ エルエルシー | 断片化ヒドロゲル |
| RU2432961C1 (ru) * | 2010-06-08 | 2011-11-10 | Илья Александрович Марков | Лекарственное средство для вагинального применения, обладающее противозачаточным и защитным от инфекционных заболеваний действием |
| US8580294B2 (en) | 2010-10-19 | 2013-11-12 | International Partnership For Microbicides | Platinum-catalyzed intravaginal rings |
| SG191893A1 (en) | 2011-01-10 | 2013-08-30 | Taris Biomedical Inc | Lidocaine regimen for the use of sustained treatment of bladder pain and irritative voiding |
| RU2598057C2 (ru) | 2011-02-04 | 2016-09-20 | ТАРИС Биомедикал ЛЛК | Имплантируемое устройство для контролируемого высвобождения лекарственного средства с низкой растворимостью |
| SG11201507294WA (en) | 2013-03-15 | 2015-10-29 | Taris Biomedical Llc | Drug delivery devices with drug-permeable component and methods |
| WO2015016036A1 (ja) * | 2013-07-29 | 2015-02-05 | 国立大学法人福井大学 | 卵子の受精可能性の検査のためのバイオマーカーおよびそれを用いた判定 |
| LT3035991T (lt) | 2013-08-19 | 2020-11-10 | Taris Biomedical Llc | Daugiablokiai vaistų vartojimo įtaisai |
| US10137031B2 (en) | 2013-11-14 | 2018-11-27 | International Partnership For Microbicides, Inc. | Combination therapy intravaginal rings |
| US11039620B2 (en) | 2014-02-19 | 2021-06-22 | Corning Incorporated | Antimicrobial glass compositions, glasses and polymeric articles incorporating the same |
| US9622483B2 (en) | 2014-02-19 | 2017-04-18 | Corning Incorporated | Antimicrobial glass compositions, glasses and polymeric articles incorporating the same |
| US11039621B2 (en) | 2014-02-19 | 2021-06-22 | Corning Incorporated | Antimicrobial glass compositions, glasses and polymeric articles incorporating the same |
| PT3125964T (pt) * | 2014-04-01 | 2024-09-09 | Poly Med Inc | Contracetivo e dispositivo relacionado |
| US10016361B2 (en) | 2014-10-24 | 2018-07-10 | Francoise Farron | PH change in the vagina as a contraceptive |
| EP3285850A1 (en) | 2015-04-23 | 2018-02-28 | TARIS Biomedical LLC | Drug delivery devices with drug-permeable component and methods |
| USD935018S1 (en) | 2020-04-07 | 2021-11-02 | The Population Council, Inc. | Contraceptive |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3545439A (en) * | 1968-01-04 | 1970-12-08 | Upjohn Co | Medicated devices and methods |
| US3803308A (en) * | 1968-09-18 | 1974-04-09 | Searle & Co | Method of contraception with a soluble non-toxic copper or zinc compound |
| US3832252A (en) | 1970-09-29 | 1974-08-27 | T Higuchi | Method of making a drug-delivery device |
| US4155991A (en) | 1974-10-18 | 1979-05-22 | Schering Aktiengesellschaft | Vaginal ring |
| IL48277A (en) | 1974-10-18 | 1978-03-10 | Schering Ag | Vaginal ring |
| US3977404A (en) * | 1975-09-08 | 1976-08-31 | Alza Corporation | Osmotic device having microporous reservoir |
| US4274410A (en) * | 1976-09-07 | 1981-06-23 | Medi-Coll, Inc. | Intravaginal contraceptive and drug release device and method for making and using same |
| US4402695A (en) * | 1980-01-21 | 1983-09-06 | Alza Corporation | Device for delivering agent in vagina |
| DE3040978A1 (de) | 1980-10-28 | 1982-05-27 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Vaginalring |
| US4381772A (en) * | 1980-11-20 | 1983-05-03 | Guistini Fernando G | Bioerodible diaphragm |
| US4582052A (en) * | 1982-03-23 | 1986-04-15 | Repromed, Inc. | Povidone-iodine dispensing fiber |
| JPS61503003A (ja) | 1984-04-19 | 1986-12-25 | ユニバ−シテイ− オブ クイ−ンスランド | 避妊方法、避妊用製剤及び避妊具 |
| US4867969A (en) * | 1986-02-07 | 1989-09-19 | Alza Corporation | Hydrogel formulation for administering non-steroidal drugs |
| US4983393A (en) | 1987-07-21 | 1991-01-08 | Maximed Corporation | Intra-vaginal device and method for sustained drug release |
| JP2590358B2 (ja) * | 1988-03-01 | 1997-03-12 | 正雄 五十嵐 | 子宮内膜症治療用の子宮内又は膣内投与製剤 |
| US5224493A (en) | 1991-01-30 | 1993-07-06 | Cadco Corporation | Contraceptive intracervical device and novel nonsystemic agents for the prevention of conception and disease |
| US5211952A (en) * | 1991-04-12 | 1993-05-18 | University Of Southern California | Contraceptive methods and formulations for use therein |
| ZA947572B (en) * | 1993-09-29 | 1995-09-28 | Hampton Roads Medical College | Contraceptive compositions |
| AU4369596A (en) * | 1994-11-21 | 1996-06-17 | Virginia L. Scofield | Sperm as vaccine vectors |
| JPH10279499A (ja) | 1997-04-04 | 1998-10-20 | Takeda Chem Ind Ltd | 子宮粘膜適用製剤 |
| US6015541A (en) * | 1997-11-03 | 2000-01-18 | Micro Therapeutics, Inc. | Radioactive embolizing compositions |
| WO1999026556A1 (en) * | 1997-11-21 | 1999-06-03 | Interag | Biodegradable intra vaginal devices |
| WO1999065538A1 (en) * | 1998-06-19 | 1999-12-23 | Oxibio, Inc. | Medical device having anti-infective and contraceptive properties |
| DE60141145D1 (enExample) * | 2000-08-24 | 2010-03-11 | Sidney Lerner | |
| US8404272B2 (en) | 2003-06-26 | 2013-03-26 | Poly-Med, Inc. | Fiber-reinforced composite rings for intravaginal controlled drug delivery |
| US20060240071A1 (en) * | 2003-07-31 | 2006-10-26 | Sidney Lerner | Non-hormonal vaginal contraceptive |
-
2001
- 2001-08-24 DE DE60141145T patent/DE60141145D1/de not_active Expired - Lifetime
- 2001-08-24 WO PCT/US2001/026475 patent/WO2002015832A1/en not_active Ceased
- 2001-08-24 CA CA002420348A patent/CA2420348C/en not_active Expired - Fee Related
- 2001-08-24 JP JP2002520746A patent/JP2004506482A/ja active Pending
- 2001-08-24 AU AU2001286726A patent/AU2001286726B2/en not_active Ceased
- 2001-08-24 AU AU8672601A patent/AU8672601A/xx active Pending
- 2001-08-24 AT AT01966190T patent/ATE455526T1/de not_active IP Right Cessation
- 2001-08-24 EP EP01966190A patent/EP1313422B1/en not_active Expired - Lifetime
- 2001-08-24 US US10/362,068 patent/US7521064B2/en not_active Expired - Fee Related
-
2009
- 2009-04-03 US US12/417,963 patent/US8268343B2/en not_active Expired - Fee Related
-
2011
- 2011-12-23 US US13/336,858 patent/US8263111B2/en not_active Expired - Fee Related
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