JP2004506482A5 - - Google Patents
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- JP2004506482A5 JP2004506482A5 JP2002520746A JP2002520746A JP2004506482A5 JP 2004506482 A5 JP2004506482 A5 JP 2004506482A5 JP 2002520746 A JP2002520746 A JP 2002520746A JP 2002520746 A JP2002520746 A JP 2002520746A JP 2004506482 A5 JP2004506482 A5 JP 2004506482A5
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- JP
- Japan
- Prior art keywords
- support structure
- composition
- days
- constructed
- acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 description 29
- 239000000463 material Substances 0.000 description 12
- 239000002253 acid Substances 0.000 description 8
- 230000001150 spermicidal effect Effects 0.000 description 7
- 238000013268 sustained release Methods 0.000 description 7
- 239000012730 sustained-release form Substances 0.000 description 7
- 210000001215 vagina Anatomy 0.000 description 7
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 6
- 239000004222 ferrous gluconate Substances 0.000 description 4
- 235000013924 ferrous gluconate Nutrition 0.000 description 4
- 229960001645 ferrous gluconate Drugs 0.000 description 4
- 230000002401 inhibitory effect Effects 0.000 description 4
- 238000003780 insertion Methods 0.000 description 4
- 230000037431 insertion Effects 0.000 description 4
- VRIVJOXICYMTAG-IYEMJOQQSA-L iron(ii) gluconate Chemical compound [Fe+2].OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O VRIVJOXICYMTAG-IYEMJOQQSA-L 0.000 description 4
- 235000010323 ascorbic acid Nutrition 0.000 description 3
- 229960005070 ascorbic acid Drugs 0.000 description 3
- 239000011668 ascorbic acid Substances 0.000 description 3
- 229920000249 biocompatible polymer Polymers 0.000 description 3
- 229920002988 biodegradable polymer Polymers 0.000 description 3
- 239000004621 biodegradable polymer Substances 0.000 description 3
- 239000003433 contraceptive agent Substances 0.000 description 3
- 230000002254 contraceptive effect Effects 0.000 description 3
- 238000004090 dissolution Methods 0.000 description 3
- 239000000017 hydrogel Substances 0.000 description 3
- 229920000642 polymer Polymers 0.000 description 3
- AEMRFAOFKBGASW-UHFFFAOYSA-N Glycolic acid Polymers OCC(O)=O AEMRFAOFKBGASW-UHFFFAOYSA-N 0.000 description 2
- TWRXJAOTZQYOKJ-UHFFFAOYSA-L Magnesium chloride Chemical compound [Mg+2].[Cl-].[Cl-] TWRXJAOTZQYOKJ-UHFFFAOYSA-L 0.000 description 2
- 229920001244 Poly(D,L-lactide) Polymers 0.000 description 2
- 229920000954 Polyglycolide Polymers 0.000 description 2
- 210000003756 cervix mucus Anatomy 0.000 description 2
- 229920000747 poly(lactic acid) Polymers 0.000 description 2
- 210000000582 semen Anatomy 0.000 description 2
- UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 description 1
- 241000124008 Mammalia Species 0.000 description 1
- 239000001110 calcium chloride Substances 0.000 description 1
- 229910001628 calcium chloride Inorganic materials 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 229920001577 copolymer Polymers 0.000 description 1
- 229910000365 copper sulfate Inorganic materials 0.000 description 1
- ARUVKPQLZAKDPS-UHFFFAOYSA-L copper(II) sulfate Chemical compound [Cu+2].[O-][S+2]([O-])([O-])[O-] ARUVKPQLZAKDPS-UHFFFAOYSA-L 0.000 description 1
- 239000011790 ferrous sulphate Substances 0.000 description 1
- 235000003891 ferrous sulphate Nutrition 0.000 description 1
- 230000003054 hormonal effect Effects 0.000 description 1
- BAUYGSIQEAFULO-UHFFFAOYSA-L iron(2+) sulfate (anhydrous) Chemical compound [Fe+2].[O-]S([O-])(=O)=O BAUYGSIQEAFULO-UHFFFAOYSA-L 0.000 description 1
- 229910000359 iron(II) sulfate Inorganic materials 0.000 description 1
- 229910001629 magnesium chloride Inorganic materials 0.000 description 1
- 239000011976 maleic acid Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 150000007524 organic acids Chemical class 0.000 description 1
- 230000001568 sexual effect Effects 0.000 description 1
- 239000000934 spermatocidal agent Substances 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22774000P | 2000-08-24 | 2000-08-24 | |
| PCT/US2001/026475 WO2002015832A1 (en) | 2000-08-24 | 2001-08-24 | Non-hormonal vaginal contraceptive |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004506482A JP2004506482A (ja) | 2004-03-04 |
| JP2004506482A5 true JP2004506482A5 (OSRAM) | 2008-10-30 |
Family
ID=22854264
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002520746A Pending JP2004506482A (ja) | 2000-08-24 | 2001-08-24 | 非ホルモン性腟内避妊用具 |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US7521064B2 (OSRAM) |
| EP (1) | EP1313422B1 (OSRAM) |
| JP (1) | JP2004506482A (OSRAM) |
| AT (1) | ATE455526T1 (OSRAM) |
| AU (2) | AU8672601A (OSRAM) |
| CA (1) | CA2420348C (OSRAM) |
| DE (1) | DE60141145D1 (OSRAM) |
| WO (1) | WO2002015832A1 (OSRAM) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE455526T1 (de) * | 2000-08-24 | 2010-02-15 | Sidney Lerner | Nicht-hormonales vaginales verhütungsmittel |
| US8404272B2 (en) * | 2003-06-26 | 2013-03-26 | Poly-Med, Inc. | Fiber-reinforced composite rings for intravaginal controlled drug delivery |
| US8399013B2 (en) | 2003-06-26 | 2013-03-19 | Poly-Med, Inc. | Partially absorbable fiber-reinforced composites for controlled drug delivery |
| US20060240071A1 (en) * | 2003-07-31 | 2006-10-26 | Sidney Lerner | Non-hormonal vaginal contraceptive |
| ES2371554T3 (es) * | 2004-12-14 | 2012-01-05 | Poly-Med, Inc. | Dispositivo intravaginal de malla en forma de anillo. |
| JP5265359B2 (ja) * | 2005-08-11 | 2013-08-14 | マサチューセッツ インスティテュート オブ テクノロジー | 膀胱内薬物送達デバイスおよび方法 |
| NZ567203A (en) | 2005-10-18 | 2010-06-25 | Starpharma Pty Ltd | Microbicidal dendrimer composition delivery system for treatment and prevention of sexually transmitted infections |
| US8399012B2 (en) * | 2006-04-17 | 2013-03-19 | Kimberly-Clark Worldwide, Inc. | Degradable therapeutic delivery device |
| US8177706B2 (en) * | 2006-07-10 | 2012-05-15 | Mcneil-Ppc, Inc. | Method of treating urinary incontinence |
| EP3047860B1 (en) | 2006-07-20 | 2024-08-28 | OrbusNeich Medical Pte. Ltd. | Bioabsorbable polymeric composition for a medical device |
| EP2073754A4 (en) | 2006-10-20 | 2012-09-26 | Orbusneich Medical Inc | BIOABSORBABLE POLYMER COMPOSITION AND MEDICAL DEVICE BACKGROUND |
| US7959942B2 (en) | 2006-10-20 | 2011-06-14 | Orbusneich Medical, Inc. | Bioabsorbable medical device with coating |
| MX348005B (es) | 2007-12-11 | 2017-05-23 | Massachusetts Inst Technology | Dispositivo implantable de liberación de fármacos y métodos para tratar la vejiga y otras vesículas o lúmenes corporales. |
| US9034365B2 (en) | 2008-05-20 | 2015-05-19 | Poly-Med, Inc. | Biostable, multipurpose, microbicidal intravaginal devices |
| CA2733468C (en) | 2008-08-09 | 2017-12-05 | Massachusetts Institute Of Technology | Implantable drug delivery device and methods of treating male genitourinary and surrounding tissues |
| JP5913095B2 (ja) | 2009-06-26 | 2016-04-27 | タリス バイオメディカル エルエルシー | 植込み型薬物送達装置及びその作製方法 |
| US9017312B2 (en) | 2009-09-10 | 2015-04-28 | Taris Biomedical Llc | Implantable device for controlled drug delivery |
| NZ599524A (en) | 2009-11-09 | 2014-04-30 | Spotlight Technology Partners Llc | Polysaccharide based hydrogels |
| WO2011057133A1 (en) | 2009-11-09 | 2011-05-12 | Spotlight Technology Partners Llc | Fragmented hydrogels |
| RU2432961C1 (ru) * | 2010-06-08 | 2011-11-10 | Илья Александрович Марков | Лекарственное средство для вагинального применения, обладающее противозачаточным и защитным от инфекционных заболеваний действием |
| US8580294B2 (en) | 2010-10-19 | 2013-11-12 | International Partnership For Microbicides | Platinum-catalyzed intravaginal rings |
| AU2012205654B2 (en) | 2011-01-10 | 2016-09-08 | Allergan, Inc. | Lidocaine regimen for the use of sustained treatment of bladder pain and irritative voiding |
| CA2825399A1 (en) | 2011-02-04 | 2012-08-09 | Taris Biomedical, Inc. | Implantable device for controlled release of low solubility drug |
| JP6517186B2 (ja) | 2013-03-15 | 2019-05-22 | タリス バイオメディカル エルエルシー | 薬物透過性構成部材を備えた薬物送達デバイス、及び方法 |
| WO2015016036A1 (ja) * | 2013-07-29 | 2015-02-05 | 国立大学法人福井大学 | 卵子の受精可能性の検査のためのバイオマーカーおよびそれを用いた判定 |
| CA2919215C (en) | 2013-08-19 | 2022-11-29 | Taris Biomedical Llc | Multi-unit drug delivery devices and methods |
| US10137031B2 (en) | 2013-11-14 | 2018-11-27 | International Partnership For Microbicides, Inc. | Combination therapy intravaginal rings |
| US9622483B2 (en) | 2014-02-19 | 2017-04-18 | Corning Incorporated | Antimicrobial glass compositions, glasses and polymeric articles incorporating the same |
| US11039621B2 (en) | 2014-02-19 | 2021-06-22 | Corning Incorporated | Antimicrobial glass compositions, glasses and polymeric articles incorporating the same |
| US11039620B2 (en) | 2014-02-19 | 2021-06-22 | Corning Incorporated | Antimicrobial glass compositions, glasses and polymeric articles incorporating the same |
| SI3125964T1 (sl) * | 2014-04-01 | 2025-01-31 | Poly-Med, Inc. | Kontraceptiv in povezana naprava |
| US10016361B2 (en) | 2014-10-24 | 2018-07-10 | Francoise Farron | PH change in the vagina as a contraceptive |
| US10894150B2 (en) | 2015-04-23 | 2021-01-19 | Taris Biomedical Llc | Drug delivery devices with drug-permeable component and methods |
| USD935018S1 (en) * | 2020-04-07 | 2021-11-02 | The Population Council, Inc. | Contraceptive |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3545439A (en) * | 1968-01-04 | 1970-12-08 | Upjohn Co | Medicated devices and methods |
| US3803308A (en) * | 1968-09-18 | 1974-04-09 | Searle & Co | Method of contraception with a soluble non-toxic copper or zinc compound |
| US3832252A (en) | 1970-09-29 | 1974-08-27 | T Higuchi | Method of making a drug-delivery device |
| US4155991A (en) * | 1974-10-18 | 1979-05-22 | Schering Aktiengesellschaft | Vaginal ring |
| IL48277A (en) | 1974-10-18 | 1978-03-10 | Schering Ag | Vaginal ring |
| US3977404A (en) * | 1975-09-08 | 1976-08-31 | Alza Corporation | Osmotic device having microporous reservoir |
| US4274410A (en) * | 1976-09-07 | 1981-06-23 | Medi-Coll, Inc. | Intravaginal contraceptive and drug release device and method for making and using same |
| US4402695A (en) * | 1980-01-21 | 1983-09-06 | Alza Corporation | Device for delivering agent in vagina |
| DE3040978A1 (de) * | 1980-10-28 | 1982-05-27 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Vaginalring |
| US4381772A (en) | 1980-11-20 | 1983-05-03 | Guistini Fernando G | Bioerodible diaphragm |
| US4582052A (en) * | 1982-03-23 | 1986-04-15 | Repromed, Inc. | Povidone-iodine dispensing fiber |
| JPS61503003A (ja) | 1984-04-19 | 1986-12-25 | ユニバ−シテイ− オブ クイ−ンスランド | 避妊方法、避妊用製剤及び避妊具 |
| US4867969A (en) | 1986-02-07 | 1989-09-19 | Alza Corporation | Hydrogel formulation for administering non-steroidal drugs |
| US4983393A (en) * | 1987-07-21 | 1991-01-08 | Maximed Corporation | Intra-vaginal device and method for sustained drug release |
| JP2590358B2 (ja) * | 1988-03-01 | 1997-03-12 | 正雄 五十嵐 | 子宮内膜症治療用の子宮内又は膣内投与製剤 |
| US5224493A (en) * | 1991-01-30 | 1993-07-06 | Cadco Corporation | Contraceptive intracervical device and novel nonsystemic agents for the prevention of conception and disease |
| US5211952A (en) * | 1991-04-12 | 1993-05-18 | University Of Southern California | Contraceptive methods and formulations for use therein |
| ZA947572B (en) * | 1993-09-29 | 1995-09-28 | Hampton Roads Medical College | Contraceptive compositions |
| AU4369596A (en) * | 1994-11-21 | 1996-06-17 | Virginia L. Scofield | Sperm as vaccine vectors |
| JPH10279499A (ja) | 1997-04-04 | 1998-10-20 | Takeda Chem Ind Ltd | 子宮粘膜適用製剤 |
| US6015541A (en) * | 1997-11-03 | 2000-01-18 | Micro Therapeutics, Inc. | Radioactive embolizing compositions |
| EP1039843A4 (en) * | 1997-11-21 | 2007-12-26 | Interag | BIODEGRADABLE INTRA-VAGINAL DEVICES |
| ATE246522T1 (de) * | 1998-06-19 | 2003-08-15 | Oxibio Inc | Implantierbare medizinische vorrichtung mit antiinfektiösen und kontrazeptiven eigenschaften |
| ATE455526T1 (de) | 2000-08-24 | 2010-02-15 | Sidney Lerner | Nicht-hormonales vaginales verhütungsmittel |
| US8404272B2 (en) | 2003-06-26 | 2013-03-26 | Poly-Med, Inc. | Fiber-reinforced composite rings for intravaginal controlled drug delivery |
| US20060240071A1 (en) * | 2003-07-31 | 2006-10-26 | Sidney Lerner | Non-hormonal vaginal contraceptive |
-
2001
- 2001-08-24 AT AT01966190T patent/ATE455526T1/de not_active IP Right Cessation
- 2001-08-24 DE DE60141145T patent/DE60141145D1/de not_active Expired - Lifetime
- 2001-08-24 AU AU8672601A patent/AU8672601A/xx active Pending
- 2001-08-24 CA CA002420348A patent/CA2420348C/en not_active Expired - Fee Related
- 2001-08-24 EP EP01966190A patent/EP1313422B1/en not_active Expired - Lifetime
- 2001-08-24 AU AU2001286726A patent/AU2001286726B2/en not_active Ceased
- 2001-08-24 JP JP2002520746A patent/JP2004506482A/ja active Pending
- 2001-08-24 US US10/362,068 patent/US7521064B2/en not_active Expired - Fee Related
- 2001-08-24 WO PCT/US2001/026475 patent/WO2002015832A1/en not_active Ceased
-
2009
- 2009-04-03 US US12/417,963 patent/US8268343B2/en not_active Expired - Fee Related
-
2011
- 2011-12-23 US US13/336,858 patent/US8263111B2/en not_active Expired - Fee Related
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