JP2004506042A5 - - Google Patents
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- JP2004506042A5 JP2004506042A5 JP2002519424A JP2002519424A JP2004506042A5 JP 2004506042 A5 JP2004506042 A5 JP 2004506042A5 JP 2002519424 A JP2002519424 A JP 2002519424A JP 2002519424 A JP2002519424 A JP 2002519424A JP 2004506042 A5 JP2004506042 A5 JP 2004506042A5
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| AR023659A1 (es) * | 1998-09-18 | 2002-09-04 | Vertex Pharma | Un compuesto inhibidor de p38, una composicion farmaceutica que lo comprende y el uso de dicha composicion en el tratamiento y prevencion de estados patologicos |
| US7351834B1 (en) | 1999-01-13 | 2008-04-01 | Bayer Pharmaceuticals Corporation | ω-Carboxyaryl substituted diphenyl ureas as raf kinase inhibitors |
| US8124630B2 (en) | 1999-01-13 | 2012-02-28 | Bayer Healthcare Llc | ω-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors |
| EP2298311B1 (en) | 1999-01-13 | 2012-05-09 | Bayer HealthCare LLC | w-Carboxy aryl substituted diphenyl ureas as p38 kinase inhibitors |
| WO2003068229A1 (en) | 2002-02-11 | 2003-08-21 | Bayer Pharmaceuticals Corporation | Pyridine, quinoline, and isoquinoline n-oxides as kinase inhibitors |
| DK1478358T3 (da) | 2002-02-11 | 2013-10-07 | Bayer Healthcare Llc | Sorafenibtosylat til behandling af sygdomme kendetegnet ved unormal angiogenese |
| CA2413475C (en) | 2002-04-25 | 2010-07-27 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Zap-70 expression as a marker for chronic lymphocytic leukemia/small lymphocytic lymphoma (cll/sll) |
| AU2003262642B2 (en) * | 2002-08-14 | 2010-06-17 | Vertex Pharmaceuticals Incorporated | Protein kinase inhibitors and uses thereof |
| CA2755297A1 (en) * | 2003-02-10 | 2004-08-26 | Vertex Pharmaceuticals Incorporated | Processes for the preparation of n-heteroaryl-n-aryl-amines by reacting an n-aryl carbamic acid ester with a halo-heteroaryl and analogous processes |
| EP1636585B2 (en) | 2003-05-20 | 2012-06-13 | Bayer HealthCare LLC | Diaryl ureas with kinase inhibiting activity |
| PL1663978T3 (pl) | 2003-07-23 | 2008-04-30 | Bayer Healthcare Llc | Fluoropodstawiony omega-karboksyarylodifenylomocznik do leczenia i profilaktyki chorób i stanów |
| US7838524B2 (en) | 2004-04-30 | 2010-11-23 | Bayer Healthcare Llc | Substituted pyrazolyl urea derivatives useful in the treatment of cancer |
| WO2006021848A1 (en) * | 2004-08-27 | 2006-03-02 | Ranbaxy Laboratories Limited | Anti-inflammatory agents |
| CA2681420A1 (en) * | 2007-03-20 | 2008-09-25 | Cadila Pharmaceuticals Limited | P38 inhibitors |
| GB0908317D0 (en) * | 2009-05-14 | 2009-06-24 | Argenta Discovery Ltd | Pharmaceutical compounds and compositions |
| CN102713618B (zh) * | 2009-09-16 | 2015-07-15 | 新基阿维罗米克斯研究公司 | 蛋白激酶复合物和抑制剂 |
| US20150044178A1 (en) | 2011-12-28 | 2015-02-12 | Kyoto Prefectural Public University Corporation | Normalization of culture of corneal endothelial cells |
| US10813920B2 (en) | 2013-11-14 | 2020-10-27 | The Doshisha | Drug for treating corneal endothelium by promoting cell proliferation or inhibiting cell damage |
| EP4096647A1 (en) * | 2020-01-30 | 2022-12-07 | Yeda Research and Development Co. Ltd | Treating acute liver disease with tlr-mik inhibitors |
| BR112022022327A2 (pt) * | 2020-05-08 | 2023-01-03 | Georgiamune Llc | Moduladores de akt3 e métodos de uso dos mesmos |
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| US6147080A (en) * | 1996-12-18 | 2000-11-14 | Vertex Pharmaceuticals Incorporated | Inhibitors of p38 |
| US6608060B1 (en) | 1996-12-18 | 2003-08-19 | Vertex Pharmaceuticals Incorporated | Inhibitors of p38 |
| US5945418A (en) | 1996-12-18 | 1999-08-31 | Vertex Pharmaceuticals Incorporated | Inhibitors of p38 |
| MY132496A (en) * | 1998-05-11 | 2007-10-31 | Vertex Pharma | Inhibitors of p38 |
| AR023659A1 (es) | 1998-09-18 | 2002-09-04 | Vertex Pharma | Un compuesto inhibidor de p38, una composicion farmaceutica que lo comprende y el uso de dicha composicion en el tratamiento y prevencion de estados patologicos |
| JP2003528084A (ja) * | 2000-03-22 | 2003-09-24 | バーテックス ファーマシューティカルズ インコーポレイテッド | ｐ３８のインヒビター |
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2001
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- 2001-08-10 AU AU8323701A patent/AU8323701A/xx active Pending
- 2001-08-10 AU AU2001283237A patent/AU2001283237B2/en not_active Ceased
- 2001-08-10 WO PCT/US2001/025015 patent/WO2002014281A1/en not_active Ceased
- 2001-08-10 JP JP2002519424A patent/JP4993838B2/ja not_active Expired - Fee Related
- 2001-08-10 CA CA002418389A patent/CA2418389A1/en not_active Abandoned
- 2001-08-10 EP EP01962021A patent/EP1309560B1/en not_active Expired - Lifetime
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2003
- 2003-02-11 US US10/365,719 patent/US7186737B2/en not_active Expired - Lifetime
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2007
- 2007-02-05 US US11/671,440 patent/US7598277B2/en not_active Expired - Lifetime
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2009
- 2009-08-28 US US12/550,042 patent/US7919513B2/en not_active Expired - Fee Related
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2011
- 2011-03-01 US US13/038,025 patent/US20110160163A1/en not_active Abandoned
-
2012
- 2012-03-29 JP JP2012077626A patent/JP2012149085A/ja not_active Withdrawn
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