JP2004506042A5 - - Google Patents
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- JP2004506042A5 JP2004506042A5 JP2002519424A JP2002519424A JP2004506042A5 JP 2004506042 A5 JP2004506042 A5 JP 2004506042A5 JP 2002519424 A JP2002519424 A JP 2002519424A JP 2002519424 A JP2002519424 A JP 2002519424A JP 2004506042 A5 JP2004506042 A5 JP 2004506042A5
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| AR023659A1 (es) * | 1998-09-18 | 2002-09-04 | Vertex Pharma | Un compuesto inhibidor de p38, una composicion farmaceutica que lo comprende y el uso de dicha composicion en el tratamiento y prevencion de estados patologicos |
| US7351834B1 (en) | 1999-01-13 | 2008-04-01 | Bayer Pharmaceuticals Corporation | ω-Carboxyaryl substituted diphenyl ureas as raf kinase inhibitors |
| EP1158985B1 (en) | 1999-01-13 | 2011-12-28 | Bayer HealthCare LLC | OMEGA-CARBOXY ARYL SUBSTITUTED DIPHENYL UREAS AS p38 KINASE INHIBITORS |
| US8124630B2 (en) | 1999-01-13 | 2012-02-28 | Bayer Healthcare Llc | ω-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors |
| ES2425739T3 (es) | 2002-02-11 | 2013-10-17 | Bayer Healthcare Llc | Sorafenib-tosilato para el tratamiento de enfermedades caracterizadas por angiogénesis anormal |
| AU2003209119A1 (en) | 2002-02-11 | 2003-09-04 | Bayer Pharmaceuticals Corporation | Pyridine, quinoline, and isoquinoline n-oxides as kinase inhibitors |
| US7329502B2 (en) | 2002-04-25 | 2008-02-12 | The United States Of America As Represented By The Department Of Health And Human Services | ZAP-70 expression as a marker for chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) |
| US7304071B2 (en) * | 2002-08-14 | 2007-12-04 | Vertex Pharmaceuticals Incorporated | Protein kinase inhibitors and uses thereof |
| WO2004072038A1 (en) * | 2003-02-10 | 2004-08-26 | Vertex Pharmaceuticals Incorporated | Processes for the preparation of n-heteroaryl-n-aryl-amines by reacting an n-aryl carbamic acid ester with a halo-heteroaryl and analogous processes |
| DE602004011340T2 (de) | 2003-05-20 | 2008-11-06 | Bayer Healthcare Llc | Diaryl-harnstoffe mit kinasehemmender wirkung |
| NZ544920A (en) | 2003-07-23 | 2009-11-27 | Bayer Healthcare Llc | 4{4-[3-(4-chloro-3-trifluoromethylphenyl)-ureido]-3-fluorophenoxy}-pyridine-2-carboxylic acid methylamide and metabolites for the treatment and prevention of diseases and conditions |
| JP2007535565A (ja) | 2004-04-30 | 2007-12-06 | バイエル ファーマシューティカルス コーポレーション | 癌の治療に有用な置換ピラゾリル尿素誘導体 |
| WO2006021848A1 (en) * | 2004-08-27 | 2006-03-02 | Ranbaxy Laboratories Limited | Anti-inflammatory agents |
| JP2010522155A (ja) * | 2007-03-20 | 2010-07-01 | カディラ ファーマシューティカルズ リミテッド | Ｐ３８阻害剤 |
| GB0908317D0 (en) * | 2009-05-14 | 2009-06-24 | Argenta Discovery Ltd | Pharmaceutical compounds and compositions |
| NZ598705A (en) | 2009-09-16 | 2014-06-27 | Celgene Avilomics Res Inc | Protein kinase conjugates and inhibitors |
| ES2917222T3 (es) | 2011-12-28 | 2022-07-07 | Kyoto Prefectural Public Univ Corp | Normalización del cultivo de células endoteliales de la córnea |
| WO2015072580A1 (ja) | 2013-11-14 | 2015-05-21 | 学校法人同志社 | 細胞増殖促進または細胞障害抑制による角膜内皮治療薬 |
| WO2021152587A1 (en) * | 2020-01-30 | 2021-08-05 | Yeda Research And Development Co. Ltd. | Treating acute liver disease with tlr-mik inhibitors |
| WO2021226510A2 (en) * | 2020-05-08 | 2021-11-11 | Georgiamune Llc | Akt3 modulators and methods of use thereof |
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| US5945418A (en) | 1996-12-18 | 1999-08-31 | Vertex Pharmaceuticals Incorporated | Inhibitors of p38 |
| US6147080A (en) * | 1996-12-18 | 2000-11-14 | Vertex Pharmaceuticals Incorporated | Inhibitors of p38 |
| US6608060B1 (en) * | 1996-12-18 | 2003-08-19 | Vertex Pharmaceuticals Incorporated | Inhibitors of p38 |
| MY132496A (en) * | 1998-05-11 | 2007-10-31 | Vertex Pharma | Inhibitors of p38 |
| AR023659A1 (es) | 1998-09-18 | 2002-09-04 | Vertex Pharma | Un compuesto inhibidor de p38, una composicion farmaceutica que lo comprende y el uso de dicha composicion en el tratamiento y prevencion de estados patologicos |
| JP2003528084A (ja) * | 2000-03-22 | 2003-09-24 | バーテックス ファーマシューティカルズ インコーポレイテッド | ｐ３８のインヒビター |
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2001
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- 2001-08-10 MX MXPA03001256A patent/MXPA03001256A/es active IP Right Grant
- 2001-08-10 JP JP2002519424A patent/JP4993838B2/ja not_active Expired - Fee Related
- 2001-08-10 CA CA002418389A patent/CA2418389A1/en not_active Abandoned
- 2001-08-10 AU AU8323701A patent/AU8323701A/xx active Pending
- 2001-08-10 EP EP01962021A patent/EP1309560B1/en not_active Expired - Lifetime
- 2001-08-10 AU AU2001283237A patent/AU2001283237B2/en not_active Ceased
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2003
- 2003-02-11 US US10/365,719 patent/US7186737B2/en not_active Expired - Lifetime
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2007
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2009
- 2009-08-28 US US12/550,042 patent/US7919513B2/en not_active Expired - Fee Related
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2011
- 2011-03-01 US US13/038,025 patent/US20110160163A1/en not_active Abandoned
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2012
- 2012-03-29 JP JP2012077626A patent/JP2012149085A/ja not_active Withdrawn
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