JP2004505965A5 - - Google Patents
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- Publication number
- JP2004505965A5 JP2004505965A5 JP2002518202A JP2002518202A JP2004505965A5 JP 2004505965 A5 JP2004505965 A5 JP 2004505965A5 JP 2002518202 A JP2002518202 A JP 2002518202A JP 2002518202 A JP2002518202 A JP 2002518202A JP 2004505965 A5 JP2004505965 A5 JP 2004505965A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- compound
- formula
- salt
- hydrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 125000000217 alkyl group Chemical group 0.000 claims 21
- 150000001875 compounds Chemical class 0.000 claims 19
- 229910052739 hydrogen Inorganic materials 0.000 claims 8
- 239000001257 hydrogen Substances 0.000 claims 8
- 125000004435 hydrogen atom Chemical class [H]* 0.000 claims 8
- 150000003839 salts Chemical class 0.000 claims 8
- 125000003545 alkoxy group Chemical group 0.000 claims 5
- 238000000034 method Methods 0.000 claims 2
- 125000001424 substituent group Chemical group 0.000 claims 2
- 239000002253 acid Substances 0.000 claims 1
- 229940100198 alkylating agent Drugs 0.000 claims 1
- 239000002168 alkylating agent Substances 0.000 claims 1
- 125000003277 amino group Chemical group 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP00402257 | 2000-08-09 | ||
| PCT/GB2001/003561 WO2002012227A2 (en) | 2000-08-09 | 2001-08-08 | Indole, azaindole and indazole derivatives having vegf inhibiting activity |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004505965A JP2004505965A (ja) | 2004-02-26 |
| JP2004505965A5 true JP2004505965A5 (OSRAM) | 2005-03-17 |
Family
ID=8173808
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002518202A Pending JP2004505965A (ja) | 2000-08-09 | 2001-08-08 | 化合物 |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US20030207878A1 (OSRAM) |
| EP (1) | EP1311500A2 (OSRAM) |
| JP (1) | JP2004505965A (OSRAM) |
| KR (1) | KR20030029812A (OSRAM) |
| CN (1) | CN1245402C (OSRAM) |
| AU (2) | AU2001279938B2 (OSRAM) |
| BR (1) | BR0113078A (OSRAM) |
| CA (1) | CA2416525A1 (OSRAM) |
| IL (1) | IL154034A0 (OSRAM) |
| MX (1) | MXPA03000874A (OSRAM) |
| NO (1) | NO20030628L (OSRAM) |
| NZ (1) | NZ523987A (OSRAM) |
| WO (1) | WO2002012227A2 (OSRAM) |
| ZA (1) | ZA200300489B (OSRAM) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TR200500745T2 (tr) | 1999-02-10 | 2005-05-23 | Astrazeneca Ab | Damar gelişimi inhibitörleri olarak kuinazolin türevleri. |
| JP3522727B2 (ja) | 1999-11-05 | 2004-04-26 | アストラゼネカ アクチボラグ | Ｖｅｇｆ阻害剤としてのキナゾリン誘導体 |
| AU2001235804A1 (en) | 2000-03-06 | 2001-09-17 | Astrazeneca Ab | Therapy |
| DE60121931T2 (de) * | 2000-04-07 | 2007-03-01 | Astrazeneca Ab | Chinazolinverbindungen |
| PL371486A1 (en) * | 2002-02-01 | 2005-06-13 | Astrazeneca Ab | Quinazoline compounds |
| TW200400034A (en) | 2002-05-20 | 2004-01-01 | Bristol Myers Squibb Co | Pyrazolo-pyrimidine aniline compounds useful as kinase inhibitors |
| TWI329112B (en) * | 2002-07-19 | 2010-08-21 | Bristol Myers Squibb Co | Novel inhibitors of kinases |
| TWI272271B (en) * | 2002-07-19 | 2007-02-01 | Bristol Myers Squibb Co | Process for preparing certain pyrrolotriazine compounds |
| KR20050056227A (ko) * | 2002-10-03 | 2005-06-14 | 탈자진 인코포레이티드 | 혈관항상성 유지제 및 그의 사용 방법 |
| NZ539408A (en) | 2002-11-04 | 2007-09-28 | Astrazeneca Ab | Quinazoline derivatives as SRC tyrosine kinase inhibitors for treating solid tumours |
| ATE458731T1 (de) | 2002-12-20 | 2010-03-15 | Pfizer Prod Inc | Pyrimidin-derivate zur behandlung von anormalem zellwachstum |
| US7109337B2 (en) | 2002-12-20 | 2006-09-19 | Pfizer Inc | Pyrimidine derivatives for the treatment of abnormal cell growth |
| AU2004218412A1 (en) | 2003-02-28 | 2004-09-16 | Oxigene, Inc. | Compositions and methods with enhanced therapeutic activity |
| US20040266688A1 (en) * | 2003-05-14 | 2004-12-30 | Nayak Nihar R | Methods for modulating endometrium |
| CA2566332A1 (en) | 2004-05-14 | 2005-11-24 | Pfizer Products Inc. | Pyrimidine derivatives for the treatment of abnormal cell growth |
| JP2007537235A (ja) | 2004-05-14 | 2007-12-20 | ファイザー・プロダクツ・インク | 異常細胞増殖の治療用ピリミジン誘導体 |
| EP1758887A1 (en) | 2004-05-14 | 2007-03-07 | Pfizer Products Incorporated | Pyrimidine derivatives for the treatment of abnormal cell growth |
| US7851623B2 (en) | 2006-11-02 | 2010-12-14 | Astrazeneca Ab | Chemical process |
| US20080190689A1 (en) * | 2007-02-12 | 2008-08-14 | Ballard Ebbin C | Inserts for engine exhaust systems |
| AU2010204555B2 (en) | 2009-01-19 | 2013-03-07 | Abbvie Inc. | Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases |
| US8486946B2 (en) | 2009-02-23 | 2013-07-16 | Merck Sharp & Dohme Corp. | Pyrazolo [4,3-c] cinnolin-3-one M1 receptor positive allosteric modulators |
| US8653079B2 (en) | 2011-08-15 | 2014-02-18 | Merck Sharp & Dohme Corp. | Pyrazolo [4,3-C] cinnolin-3-one M1 receptor positive allosteric modulators |
| CA2952857A1 (en) * | 2014-06-19 | 2015-12-23 | Merial, Inc. | Parasiticidal compositions comprising indole derivatives, methods and uses thereof |
| JP2022532379A (ja) * | 2019-05-14 | 2022-07-14 | ザ スクリプス リサーチ インスティテュート | 神経変性および代謝障害の処置のための化合物 |
| CN116406271B (zh) * | 2020-07-14 | 2024-09-24 | 南京再明医药有限公司 | 双环类化合物 |
| MX2023012060A (es) | 2021-04-13 | 2024-01-22 | Nuvalent Inc | Heterociclos con sustitucion amino para tratar canceres con mutaciones de egfr. |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3987332A (en) * | 1975-10-09 | 1976-10-19 | Varian Associates | Gang tuner for multi-cavity klystron |
| US5480883A (en) * | 1991-05-10 | 1996-01-02 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | Bis mono- and bicyclic aryl and heteroaryl compounds which inhibit EGF and/or PDGF receptor tyrosine kinase |
| US5237629A (en) * | 1992-03-19 | 1993-08-17 | The United States Of America As Represented By The United States Department Of Energy | Digitally controlled distributed phase shifter |
| US5440270A (en) * | 1992-07-14 | 1995-08-08 | Linear Technology Corporation | Linear-phase filter having high gain selectivity |
| SE500986C2 (sv) * | 1993-07-20 | 1994-10-17 | Telia Ab | Förfarande och anordning för synkronisering i digitalt transmissionssystem av typen OFDM |
| TW414798B (en) * | 1994-09-07 | 2000-12-11 | Thomae Gmbh Dr K | Pyrimido (5,4-d) pyrimidines, medicaments comprising these compounds, their use and processes for their preparation |
| US5639757A (en) * | 1995-05-23 | 1997-06-17 | Pfizer Inc. | 4-aminopyrrolo[2,3-d]pyrimidines as tyrosine kinase inhibitors |
| US6395733B1 (en) * | 1995-06-07 | 2002-05-28 | Pfizer Inc | Heterocyclic ring-fused pyrimidine derivatives |
| GB9604361D0 (en) * | 1996-02-29 | 1996-05-01 | Pharmacia Spa | 4-Substituted pyrrolopyrimidine compounds as tyrosine kinase inhibitors |
| JP3727406B2 (ja) * | 1996-03-07 | 2005-12-14 | 株式会社日立国際電気 | 関数変換演算器 |
| HRP970371A2 (en) * | 1996-07-13 | 1998-08-31 | Kathryn Jane Smith | Heterocyclic compounds |
| CA2263479A1 (en) * | 1996-09-25 | 1998-04-02 | Zeneca Limited | Quinoline derivatives inhibiting the effect of growth factors such as vegf |
| CO4950519A1 (es) * | 1997-02-13 | 2000-09-01 | Novartis Ag | Ftalazinas, preparaciones farmaceuticas que las comprenden y proceso para su preparacion |
| US6162804A (en) * | 1997-09-26 | 2000-12-19 | Merck & Co., Inc. | Tyrosine kinase inhibitors |
| JP2001522853A (ja) * | 1997-11-11 | 2001-11-20 | ファイザー・プロダクツ・インク | 抗癌剤として有用なチエノピリミジンおよびチエノピリジン誘導体 |
| JPH11259454A (ja) * | 1998-03-09 | 1999-09-24 | Sharp Corp | フーリエ変換装置 |
| BR9912938B1 (pt) * | 1998-08-11 | 2011-06-28 | derivados de isoquinolina, composição que os compreende, processo para preparação e uso dos mesmos. | |
| US20030162795A1 (en) * | 1998-10-22 | 2003-08-28 | Pfizer Inc. | Thienopyrimidine and thienopyridine derivatives useful as anticancer agents |
| KR200212866Y1 (ko) * | 1998-12-26 | 2001-02-15 | 서평원 | 선왜곡 방식 전력증폭기용 능동 왜곡신호 발생회로 |
| NZ516292A (en) * | 1999-05-21 | 2004-01-30 | Bristol Myers Squibb Co | Pyrrolotriazine inhibitors of kinases |
| US6982265B1 (en) * | 1999-05-21 | 2006-01-03 | Bristol Myers Squibb Company | Pyrrolotriazine inhibitors of kinases |
| GT200000158A (es) * | 1999-09-28 | 2002-03-16 | Piridinas y piridacinas sustituidas con actividad de inhibicion de angiogenesis. | |
| MXPA02012034A (es) * | 2000-06-06 | 2003-04-25 | Pfizer Prod Inc | Derivados de tiofeno utiles como agentes anticancerosos. |
-
2001
- 2001-08-08 MX MXPA03000874A patent/MXPA03000874A/es not_active Application Discontinuation
- 2001-08-08 IL IL15403401A patent/IL154034A0/xx unknown
- 2001-08-08 BR BR0113078-1A patent/BR0113078A/pt not_active IP Right Cessation
- 2001-08-08 JP JP2002518202A patent/JP2004505965A/ja active Pending
- 2001-08-08 EP EP01958210A patent/EP1311500A2/en not_active Withdrawn
- 2001-08-08 NZ NZ523987A patent/NZ523987A/en unknown
- 2001-08-08 US US10/343,236 patent/US20030207878A1/en not_active Abandoned
- 2001-08-08 AU AU2001279938A patent/AU2001279938B2/en not_active Ceased
- 2001-08-08 CN CNB018166962A patent/CN1245402C/zh not_active Expired - Fee Related
- 2001-08-08 AU AU7993801A patent/AU7993801A/xx active Pending
- 2001-08-08 KR KR10-2003-7001852A patent/KR20030029812A/ko not_active Ceased
- 2001-08-08 CA CA002416525A patent/CA2416525A1/en not_active Abandoned
- 2001-08-08 WO PCT/GB2001/003561 patent/WO2002012227A2/en not_active Ceased
-
2003
- 2003-01-17 ZA ZA200300489A patent/ZA200300489B/en unknown
- 2003-02-07 NO NO20030628A patent/NO20030628L/no not_active Application Discontinuation
-
2006
- 2006-02-16 US US11/355,006 patent/US20060148819A1/en not_active Abandoned
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